DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Kalmár, Alexandra ^a,b   Péterfia, Bálint ^a,b   Hollósi, Péter ^a,b   Galamb, Orsolya ^b   Spisák, Sándor ^b   Wichmann, Barnabás ^b   Bodor, András ^c   Tóth, Kinga ^a   Patai, Árpád V ^a   Valcz, Gábor ^b   Nagy, Zsófia Brigitta ^a   Kubák, Vivien ^a   Tulassay, Zsolt ^a,b   Kovalszky, Ilona ^a   Molnár, Béla ^a,b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Colorectal cancer; DNA methylation; Gene expression; Laser capture microdissection; Pyrosequencing

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; SUPPRESSOR OF CYTOKINE SIGNALING 3; IMMUNOGLOBULIN RECEPTOR; MAL PROTEIN, HUMAN; MEMBRANE PROTEIN; MYELIN AND LYMPHOCYTE PROTEIN; NERVE PROTEIN; PRIMA1 PROTEIN, HUMAN; PROSTAGLANDIN D2 RECEPTOR; PROSTAGLANDIN RECEPTOR; SFRP1 PROTEIN, HUMAN; SIGNAL PEPTIDE; TUMOR MARKER;

ARTICLE; BCL2 GENE; COL1A2 GENE; COLON BIOPSY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA METHYLATION; EPITHELIUM CELL; GENE; GENE EXPRESSION PROFILING; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER CAPTURE MICRODISSECTION; MAJOR CLINICAL STUDY; MAL GENE; MICROARRAY ANALYSIS; PRIMA1 GENE; PTGDR GENE; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; SFRP1 GENE; SFRP2 GENE; SOCS3 GENE; STROMA CELL; THBS2 GENE; UPREGULATION; ADENOMA; BIOSYNTHESIS; COLORECTAL TUMOR; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION; PROMOTER REGION; TUMOR CELL LINE;

ADENOMA; BIOMARKERS, TUMOR; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MYELIN AND LYMPHOCYTE-ASSOCIATED PROTEOLIPID PROTEINS; NERVE TISSUE PROTEINS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RECEPTORS, IMMUNOLOGIC; RECEPTORS, PROSTAGLANDIN; RNA, MESSENGER;

EID: 84945182799     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1687-x     Document Type: Article

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