Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-versus-Host Disease and Retains Graft-versus-Leukemia Activity

ACS Nano

Volumn 10, Issue 6, 2016, Pages 6189-6200

  Zhao, Shuting ^a,b   Zhang, Lingling ^c,f   Han, Jianfeng ^c   Chu, Jianhong ^c,g   Wang, Hai ^a,b   Chen, Xilin ^c   Wang, Youwei ^c   Tun, Norm ^c   Lu, Lanchun ^d   Bai, Xue Feng ^d   Yearsley, Martha ^d   Devine, Steven ^c,e   He, Xiaoming ^a,b,c   Yu, Jianhua ^c,e  

^a The Ohio State University   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d Department of Radiation Oncology ^*  (United States)

^e THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^f ANHUI MEDICAL UNIVERSITY   (China)

^g SOOCHOW UNIVERSITY   (China)

Author keywords

alginate; chitosan; graft versus host disease; graft versus leukemia; immunoisolation; nanomaterials; T cells

Indexed keywords

ALGINATE; BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; CHITIN; CHITOSAN; CYTOLOGY; DISEASES; GRAFT VS. HOST REACTIONS; GRAFTING (CHEMICAL); GRAFTS; NANOSTRUCTURED MATERIALS; NANOTECHNOLOGY; POROUS MATERIALS; STEM CELLS; T-CELLS;

BONE MARROW CELLS; CYTOKINE SECRETIONS; EFFECTIVE APPROACHES; GRAFT VERSUS HOST DISEASE; HEMATOLOGICAL MALIGNANCIES; HEMATOPOIETIC STEM CELLS; IMMUNO-ISOLATION; NANO-ENCAPSULATION;

CELLS;

NANOCOMPOSITE;

ALLOTRANSPLANTATION; ANIMAL; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; LEUKEMIA; MOUSE; T LYMPHOCYTE;

ANIMALS; GRAFT VS HOST DISEASE; GRAFT VS LEUKEMIA EFFECT; LEUKEMIA; MICE; NANOCOMPOSITES; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS;

EID: 84976530404     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.6b02206     Document Type: Article

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