Chitosan-Decorated Doxorubicin-Encapsulated Nanoparticle Targets and Eliminates Tumor Reinitiating Cancer Stem-like Cells

ACS Nano

Volumn 9, Issue 6, 2015, Pages 5725-5740

  Rao, Wei ^a,b   Wang, Hai ^a,b,c   Han, Jianfeng ^c,d   Zhao, Shuting ^a,b   Dumbleton, Jenna ^a,b   Agarwal, Pranay ^a,b   Zhang, Wujie ^e   Zhao, Gang ^f   Yu, Jianhua ^c,d   Zynger, Debra L ^d   Lu, Xiongbin ^g   He, Xiaoming ^a,b,c  

^a The Ohio State University   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e MILWAUKEE SCHOOL OF ENGINEERING   (United States)

^f UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^g UNIVERSITY OF TEXAS   (United States)

Author keywords

cancer stem like cell; CD44; chitosan; EPR; nanoparticle; targeting

Indexed keywords

CELLS; CHEMOTHERAPY; CHITIN; CHITOSAN; CYTOLOGY; DISEASES; MOBILE SECURITY; PARAMAGNETIC RESONANCE; PATIENT TREATMENT; TOXICITY; TUMORS;

ACIDIC ENVIRONMENT; CD44; ENCAPSULATED NANOPARTICLES; NANOPARTICLE SYSTEMS; POLYMERIC NANOPARTICLES; SYSTEMIC TOXICITIES; TARGETING; TUMOR MICROENVIRONMENT;

NANOPARTICLES;

ANTINEOPLASTIC ANTIBIOTIC; CHITOSAN; DOXORUBICIN; NANOPARTICLE;

ANIMAL; CANCER STEM CELL; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; FEMALE; HUMAN; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF 7 CELL LINE; MOUSE; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE; STRUCTURE ACTIVITY RELATION; TUMOR CELL CULTURE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; CHITOSAN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; MICE; MICE, INBRED NOD; MICE, SCID; NANOPARTICLES; NEOPLASTIC STEM CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84935022493     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn506928p     Document Type: Article

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