In vivo antitumor effect of CD40L-transduced tumor cells as a vaccine for B-cell lymphoma

Cancer Research

Volumn 62, Issue 11, 2002, Pages 3195-3199

  Briones, Javier ^a   Timmerman, John ^a   Levy, Ronald ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; B7 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD86 ANTIGEN; FAS ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; TUMOR VACCINE;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXICITY; DNA MODIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSDUCTION; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR CELL; TUMOR GROWTH;

ADENOVIRIDAE; ANIMALS; ANTIBODY FORMATION; CANCER VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; IMMUNOTHERAPY, ACTIVE; LYMPHOMA, B-CELL; MICE; MICE, INBRED BALB C; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0036606585     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Costimulatory wars: The tumor menace
2. Follicular lymphomas can be induced to present alloantigen efficiently: A conceptual model to improve their tumor immunogenicity
3. Functional expression of adhesion receptors and costimulatory molecules by fresh and immortalized B-cell non-Hodgkin's lymphoma cells
4. Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells
5. Structural characteristics of CD40 ligand that determine biological function
6. The CD40 antigen and its ligand
7. Functions of CD40 on B cells, dendritic cells and other cells
8. CD40-CD40 ligand interactions stimulate B cell antigen processing
9. CD40-activated human B cells: An alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy
10. CD40 triggering of chronic lymphocytic leukemia B cells results in efficient allogeneic presentation and cytotoxic T lymphocyte induction by up-regulation of CD80 and CD86 costimulatory molecules
11. Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia
12. CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia
13. Establishment and characterization of BALB/c lymphoma lines with B cell properties
14. Recombinant adenovirus vaccine encoding a chimeric T-cell antigen receptor induces protective immunity against a T-cell lymphoma
15. Immunostimulatory effects of a plasmid expressing CD40 ligand (CD154) on gene immunization
16. Idiotype-encoding recombinant adenoviruses provide protective immunity against murine B-cell lymphomas
17. Tumor immunotherapy: The tumor cell as antigen-presenting cell
18. Gene transfer as cancer therapy
19. Paracrine cytokine adjuvants in cancer immunotherapy
20. Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro
21. T cell activation following infection of primary follicle center lymphoma B cells with adenovirus encoding CD154
22. CD40 ligand induces an antileukemia immune response in vivo
23. Leukemia cells transduced with HSV-1 amplicons expressing CD70 and IL-2 stimulate a protective anti-leukemic response in vivo
24. Cardoso TARC are secreted by malignant B-cell precursors following CD40 ligation and support the migration of leukemia-specific T cells
25. Expression of costimulatory molecules in tumor cells by recombinant viruses stimulates antitumor immunity against B-cell lymphoma in vivo
26. A mechanism for selective recruitment of CD8 T cells into B7-1-transfected plasmacytoma
27. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
28. Antitumor responses induced by transgenic expression of CD40 ligand
29. An oral CD40 ligand gene therapy against lymphoma using attenuated Salmonella typhimurium
30. CD4+ T-cell induction of Fas-mediated apoptosis in Burkitt's lymphoma cells
31. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLS
32. Conversion of tumor-specific CD4+ T-cell tolerance to T-cell printing through in vivo ligation of CD40