Microencapsulation of cells, including islets, within stable ultra-thin membranes of maleimide-conjugated PEG-lipid with multifunctional crosslinkers

Biomaterials

Volumn 34, Issue 11, 2013, Pages 2683-2693

  Teramura, Yuji ^a   Oommen, Oommen P ^b   Olerud, Johan ^a   Hilborn, Jöns ^b   Nilsson, Bo ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Bioartificial pancreas; Cell surface modification; Diabetes; Islets; Microencapsulation; Poly(ethylene glycol) lipid (PEG lipid)

Indexed keywords

BIO-ARTIFICIAL PANCREAS; CELL SURFACES; CELL SUSPENSION; CROSS-LINKERS; DIFFUSION LIMITATIONS; ENCAPSULATED CELL; EQUILIBRIUM STATE; IMMUNOSUPPRESSIVE THERAPY; INSULIN RELEASE; ISLET TRANSPLANTATION; ISLETS; ISLETS OF LANGERHANS; MALEIMIDE GROUP; MEMBRANE FORMATION; MEMBRANE THICKNESS; MICROENCAPSULATION; MICROMETER LEVELS; POLYMER MEMBRANE; SEMI-PERMEABLE MEMBRANES; THROMBOGENICITY; ULTRA-THIN; ULTRA-THIN MEMBRANES; WHOLE BLOOD;

CELL CULTURE; CELL MEMBRANES; CONJUGATED POLYMERS; FUNCTIONAL POLYMERS; GLUCOSE; GRAFTS; INSULIN; MEDICAL PROBLEMS; MEMBRANES; MICELLES; OXYGEN PERMEABLE MEMBRANES; PACKAGING; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; THICKNESS MEASUREMENT; TISSUE;

ENCAPSULATION;

GLUCOSE; INSULIN; MACROGOL; MALEIMIDE; POLY(ETHYLENE GLYCOL) LIPID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; CELL MEMBRANE; CELL STRUCTURE; CELL SURFACE; CONTROLLED STUDY; INSULIN RELEASE; MEMBRANE PERMEABILITY; MICELLE; MICROENCAPSULATION; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL;

ANIMALS; APYRASE; CELL MEMBRANE; CELLS, IMMOBILIZED; ENDOTHELIAL CELLS; ENZYMES, IMMOBILIZED; ERYTHROCYTES; GRAFT SURVIVAL; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; LIPIDS; MALE; MALEIMIDES; MATERIALS TESTING; MICE; MICE, INBRED C57BL; PERMEABILITY; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; RABBITS; SWINE; THROMBIN;

EID: 84873086882     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.015     Document Type: Article

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