-
1
-
-
77955472579
-
Evolving challenges in hepatic fibrosis
-
Friedman SL. Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol 2010;7:425-436.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 425-436
-
-
Friedman, S.L.1
-
2
-
-
84926301373
-
Resetting the transcription factor network reverses terminal chronic hepatic failure
-
Nishikawa T, Bell A, Brooks JM, Setoyama K, Melis M, Han B, et al. Resetting the transcription factor network reverses terminal chronic hepatic failure. J Clin Invest 2015;125:1533-1544.
-
(2015)
J Clin Invest
, vol.125
, pp. 1533-1544
-
-
Nishikawa, T.1
Bell, A.2
Brooks, J.M.3
Setoyama, K.4
Melis, M.5
Han, B.6
-
3
-
-
84928209791
-
Liver sinusoidal endothelial cells in hepatic fibrosis
-
DeLeve LD. Liver sinusoidal endothelial cells in hepatic fibrosis. Hepatology 2015;61:1740-1746.
-
(2015)
Hepatology
, vol.61
, pp. 1740-1746
-
-
DeLeve, L.D.1
-
4
-
-
84954055301
-
Normal and Fibrotic rat livers demonstrate shear strain softening and compression stiffening: a model for soft tissue mechanics
-
Perepelyuk M, Chin L, Cao X, van Oosten A, Shenoy VB, Janmey PA, et al. Normal and Fibrotic rat livers demonstrate shear strain softening and compression stiffening: a model for soft tissue mechanics. PLoS One 2016;11:e0146588.
-
(2016)
PLoS One
, vol.11
-
-
Perepelyuk, M.1
Chin, L.2
Cao, X.3
van Oosten, A.4
Shenoy, V.B.5
Janmey, P.A.6
-
5
-
-
84878527104
-
Smoothened is a master regulator of adult liver repair
-
Michelotti GA, Xie G, Swiderska M, Choi SS, Karaca G, Krüger L, et al. Smoothened is a master regulator of adult liver repair. J Clin Invest 2013;123:2380-2394.
-
(2013)
J Clin Invest
, vol.123
, pp. 2380-2394
-
-
Michelotti, G.A.1
Xie, G.2
Swiderska, M.3
Choi, S.S.4
Karaca, G.5
Krüger, L.6
-
6
-
-
84865571180
-
Yes-associated protein regulates the hepatic response after bile duct ligation
-
Bai H, Zhang N, Xu Y, Chen Q, Khan M, Potter JJ, et al. Yes-associated protein regulates the hepatic response after bile duct ligation. Hepatology 2012;56:1097-1107.
-
(2012)
Hepatology
, vol.56
, pp. 1097-1107
-
-
Bai, H.1
Zhang, N.2
Xu, Y.3
Chen, Q.4
Khan, M.5
Potter, J.J.6
-
7
-
-
84983102616
-
The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
-
Mannaerts I, Leite SB, Verhulst S, Claerhout S, Eysackers N, Thoen LF et al. The Hippo pathway effector YAP controls mouse hepatic stellate cell activation. J Hepatol 2015;63:679-688.
-
(2015)
J Hepatol
, vol.63
, pp. 679-688
-
-
Mannaerts, I.1
Leite, S.B.2
Verhulst, S.3
Claerhout, S.4
Eysackers, N.5
Thoen, L.F.6
-
8
-
-
84904317272
-
Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration
-
Grijalva JL, Huizenga M, Mueller K, Rodriguez S, Brazzo J, Camargo F, et al. Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration. Am J Physiol Gastrointest Liver Physiol 2014;307:G196-G204.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.307
, pp. G196-G204
-
-
Grijalva, J.L.1
Huizenga, M.2
Mueller, K.3
Rodriguez, S.4
Brazzo, J.5
Camargo, F.6
-
9
-
-
84904060793
-
Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy
-
Swiderska-Syn M, Syn WK, Xie G, Krüger L, Machado MV, Karaca G, et al. Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. Gut 2014;63:1333-1344.
-
(2014)
Gut
, vol.63
, pp. 1333-1344
-
-
Swiderska-Syn, M.1
Syn, W.K.2
Xie, G.3
Krüger, L.4
Machado, M.V.5
Karaca, G.6
-
10
-
-
84942980967
-
Developmental biology: on the origin of liver regeneration
-
Ray K. Developmental biology: on the origin of liver regeneration. Nat Rev Gastroenterol Hepatol 2015;12:549.
-
(2015)
Nat Rev Gastroenterol Hepatol
, vol.12
, pp. 549
-
-
Ray, K.1
-
11
-
-
84893143662
-
Liver renewal: detecting misrepair and optimizing regeneration
-
Machado MV, Diehl AM. Liver renewal: detecting misrepair and optimizing regeneration. Mayo Clin Proc 2014;89:120-130.
-
(2014)
Mayo Clin Proc
, vol.89
, pp. 120-130
-
-
Machado, M.V.1
Diehl, A.M.2
-
12
-
-
77951436593
-
Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice
-
Ochoa B, Syn WK, Delgado I, Karaca GF, Jung Y, Wang J, et al. Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice. Hepatology 2010;51:1712-1723.
-
(2010)
Hepatology
, vol.51
, pp. 1712-1723
-
-
Ochoa, B.1
Syn, W.K.2
Delgado, I.3
Karaca, G.F.4
Jung, Y.5
Wang, J.6
-
13
-
-
84942194781
-
Yes-associated protein in the liver: regulation of hepatic development, repair, cell fate determination and tumorigenesis
-
Nguyen Q, Anders RA, Alpini G, Bai H. Yes-associated protein in the liver: regulation of hepatic development, repair, cell fate determination and tumorigenesis. Dig Liver Dis 2015;47:826-835.
-
(2015)
Dig Liver Dis
, vol.47
, pp. 826-835
-
-
Nguyen, Q.1
Anders, R.A.2
Alpini, G.3
Bai, H.4
-
14
-
-
84942822765
-
Morphogen-related therapeutic targets for liver fibrosis
-
Fung E, Tsukamoto H. Morphogen-related therapeutic targets for liver fibrosis. Clin Res Hepatol Gastroenterol 2015;39(Suppl 1):S69-S74.
-
(2015)
Clin Res Hepatol Gastroenterol
, vol.39
, pp. S69-S74
-
-
Fung, E.1
Tsukamoto, H.2
-
15
-
-
84878633534
-
Hepatic stellate cells—the pericytes in the liver
-
Hellerbrand C. Hepatic stellate cells—the pericytes in the liver. Pflugers Arch 2013;465:775-778.
-
(2013)
Pflugers Arch
, vol.465
, pp. 775-778
-
-
Hellerbrand, C.1
-
16
-
-
0001276586
-
Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
-
Higgins G, Anderson R. Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal. Arch Pathol 1931;12:186-202.
-
(1931)
Arch Pathol
, vol.12
, pp. 186-202
-
-
Higgins, G.1
Anderson, R.2
-
17
-
-
77952336576
-
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
-
Lee KP, Lee JH, Kim TS, Park HD, Byun JS, Kim MC, et al. The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proc Natl Acad Sci U S A 2010;107:8248-8253.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8248-8253
-
-
Lee, K.P.1
Lee, J.H.2
Kim, T.S.3
Park, H.D.4
Byun, J.S.5
Kim, M.C.6
-
18
-
-
84951086299
-
Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer
-
Yimlamai D, Fowl BH, Camargo FD. Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer. J Hepatol 2015;63:1491-1501.
-
(2015)
J Hepatol
, vol.63
, pp. 1491-1501
-
-
Yimlamai, D.1
Fowl, B.H.2
Camargo, F.D.3
-
19
-
-
84942194781
-
Yes-associated protein in the liver: regulation of hepatic development, repair, cell fate determination and tumorigenesis
-
Nguyen Q, Anders RA, Alpini G, Bai H. Yes-associated protein in the liver: regulation of hepatic development, repair, cell fate determination and tumorigenesis. Dig Liver Dis 2015;47:826-835.
-
(2015)
Dig Liver Dis
, vol.47
, pp. 826-835
-
-
Nguyen, Q.1
Anders, R.A.2
Alpini, G.3
Bai, H.4
-
20
-
-
84904024982
-
KRAS and YAP1 converge to regulate EMT and tumor survival
-
Shao DD, Xue W, Krall EB, Bhutkar A, Piccionie F, Wang X, et al. KRAS and YAP1 converge to regulate EMT and tumor survival. Cell 2014;158:171-184.
-
(2014)
Cell
, vol.158
, pp. 171-184
-
-
Shao, D.D.1
Xue, W.2
Krall, E.B.3
Bhutkar, A.4
Piccionie, F.5
Wang, X.6
-
21
-
-
70350534843
-
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Katoh Y, Katoh M. Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. Curr Mol Med 2009;9:873-886.
-
(2009)
Curr Mol Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
22
-
-
84907996370
-
Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation
-
Alder O, Cullum R, Lee S, Kan AC, Wei W, Yi Y, et al. Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation. Cell Rep 2014;9:261-271.
-
(2014)
Cell Rep
, vol.9
, pp. 261-271
-
-
Alder, O.1
Cullum, R.2
Lee, S.3
Kan, A.C.4
Wei, W.5
Yi, Y.6
-
23
-
-
84907033777
-
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
-
Saha SK, Parachoniak CA, Ghanta KS, Fitmant J, Ross KN, Najem MS, et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature 2014;513:110-114.
-
(2014)
Nature
, vol.513
, pp. 110-114
-
-
Saha, S.K.1
Parachoniak, C.A.2
Ghanta, K.S.3
Fitmant, J.4
Ross, K.N.5
Najem, M.S.6
-
24
-
-
84879432007
-
Principles of liver regeneration and growth homeostasis
-
Michalopoulos GK. Principles of liver regeneration and growth homeostasis. Compr Physiol 2013;3:485-513.
-
(2013)
Compr Physiol
, vol.3
, pp. 485-513
-
-
Michalopoulos, G.K.1
-
25
-
-
84915755718
-
Hepatic stellate cells contribute to progenitor cells and liver regeneration
-
Kordes C, Sawitza I, Gotze S, Herebian D, Haussinger D. Hepatic stellate cells contribute to progenitor cells and liver regeneration. J Clin Invest 2014;124:5503-5515.
-
(2014)
J Clin Invest
, vol.124
, pp. 5503-5515
-
-
Kordes, C.1
Sawitza, I.2
Gotze, S.3
Herebian, D.4
Haussinger, D.5
-
26
-
-
84930654452
-
Hepatic fibrosis: concept to treatment
-
Trautwein C, Friedman SL, Schuppan D, Pinzani M. Hepatic fibrosis: concept to treatment. J Hepatol 2015;62(1 Suppl):S15-S24.
-
(2015)
J Hepatol
, vol.62
, Issue.1
, pp. S15-S24
-
-
Trautwein, C.1
Friedman, S.L.2
Schuppan, D.3
Pinzani, M.4
-
27
-
-
72549090299
-
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
-
Fernandez LA, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S, et al. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev 2009;23:2729-2741.
-
(2009)
Genes Dev
, vol.23
, pp. 2729-2741
-
-
Fernandez, L.A.1
Northcott, P.A.2
Dalton, J.3
Fraga, C.4
Ellison, D.5
Angers, S.6
-
28
-
-
37349005990
-
Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis
-
Danovi SA, Rossi M, Gudmundsdottir K, Yuan M, Melino G, Basu S. Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis. Cell Death Differ 2008;15:217-219.
-
(2008)
Cell Death Differ
, vol.15
, pp. 217-219
-
-
Danovi, S.A.1
Rossi, M.2
Gudmundsdottir, K.3
Yuan, M.4
Melino, G.5
Basu, S.6
-
29
-
-
0037168526
-
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration
-
Wang X, Kiyokawa H, Dennewitz MB, Costa RH. The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A 2002;99:16881-16886.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 16881-16886
-
-
Wang, X.1
Kiyokawa, H.2
Dennewitz, M.B.3
Costa, R.H.4
-
30
-
-
0027445066
-
Cyclin and cyclin-dependent kinase 1 mRNA expression in models of regenerating liver and human liver diseases
-
Albrecht JH, Hoffman JS, Kren BT, Steer CJ. Cyclin and cyclin-dependent kinase 1 mRNA expression in models of regenerating liver and human liver diseases. Am J Physiol 1993;265(5 Pt 1):G857-G864.
-
(1993)
Am J Physiol
, vol.265
, Issue.5
, pp. G857-G864
-
-
Albrecht, J.H.1
Hoffman, J.S.2
Kren, B.T.3
Steer, C.J.4
-
31
-
-
14944386541
-
Amphiregulin: an early trigger of liver regeneration in mice
-
Berasain C, García-Trevijano ER, Castillo J, Erroba E, Lee DC, Prieto J, et al. Amphiregulin: an early trigger of liver regeneration in mice. Gastroenterology 2005;128:424-432.
-
(2005)
Gastroenterology
, vol.128
, pp. 424-432
-
-
Berasain, C.1
García-Trevijano, E.R.2
Castillo, J.3
Erroba, E.4
Lee, D.C.5
Prieto, J.6
-
32
-
-
82455210238
-
Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation
-
Urtasun R, Latasa MU, Demartis MI, Balzani S, Goni S, Garcia-Irigoyen O, et al. Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation. Hepatology 2011;54:2149-2158.
-
(2011)
Hepatology
, vol.54
, pp. 2149-2158
-
-
Urtasun, R.1
Latasa, M.U.2
Demartis, M.I.3
Balzani, S.4
Goni, S.5
Garcia-Irigoyen, O.6
|