-
1
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher, P. M., Brown, M. A., McCarthy, M. I. & Yang, J. Five years of GWAS discovery. Am. J. Hum. Genet. 90, 7-24 (2012).
-
(2012)
Am. J. Hum. Genet
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
2
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Bernstein, B. E. et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012).
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Bernstein, B.E.1
-
3
-
-
84863337808
-
Is epidemiology ready for epigenetics?
-
Relton, C. L. & Davey Smith, G. Is epidemiology ready for epigenetics? Int. J. Epidemiol. 41, 5-9 (2012).
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 5-9
-
-
Relton, C.L.1
Davey Smith, G.2
-
4
-
-
79960556965
-
Epigenome-wide association studies for common human diseases
-
Rakyan, V. K., Down, T. A., Balding, D. J. & Beck, S. Epigenome-wide association studies for common human diseases. Nature Rev. Genet. 12, 529-541 (2011).
-
(2011)
Nature Rev. Genet
, vol.12
, pp. 529-541
-
-
Rakyan, V.K.1
Down, T.A.2
Balding, D.J.3
Beck, S.4
-
5
-
-
85027954125
-
DNA methylation profiling in the clinic: Applications and challenges
-
Heyn, H. & Esteller, M. DNA methylation profiling in the clinic: applications and challenges. Nature Rev. Genet. 13, 679-692 (2012).
-
(2012)
Nature Rev. Genet
, vol.13
, pp. 679-692
-
-
Heyn, H.1
Esteller, M.2
-
6
-
-
84857727055
-
Genomic imprinting and its relevance to congenital disease, infertility, molar pregnancy and induced pluripotent stem cell
-
Tomizawa, S. & Sasaki, H. Genomic imprinting and its relevance to congenital disease, infertility, molar pregnancy and induced pluripotent stem cell. J. Hum. Genet. 57, 84-91 (2012).
-
(2012)
J. Hum. Genet
, vol.57
, pp. 84-91
-
-
Tomizawa, S.1
Sasaki, H.2
-
7
-
-
80053144962
-
A decade of exploring the cancer epigenome - Biological and translational implications
-
Baylin, S. B. & Jones, P. A. A decade of exploring the cancer epigenome - biological and translational implications. Nature Rev. Cancer 11, 726-734 (2011).
-
(2011)
Nature Rev. Cancer
, vol.11
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
8
-
-
84855956247
-
Epigenetics and the environment: Emerging patterns and implications
-
Feil, R. & Fraga, M. F. Epigenetics and the environment: emerging patterns and implications. Nature Rev. Genet. 12, 97-109 (2011).
-
(2011)
Nature Rev. Genet
, vol.12
, pp. 97-109
-
-
Feil, R.1
Fraga, M.F.2
-
9
-
-
84867251622
-
450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
-
Joubert, B. R. et al. 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. Environ. Health Perspect. 120, 1425-1431 (2012).
-
(2012)
Environ. Health Perspect
, vol.120
, pp. 1425-1431
-
-
Joubert, B.R.1
-
10
-
-
79953706343
-
Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
-
Breitling, L. P., Yang, R., Korn, B., Burwinkel, B. & Brenner, H. Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am. J. Hum. Genet. 88, 450-457 (2011).
-
(2011)
Am. J. Hum. Genet
, vol.88
, pp. 450-457
-
-
Breitling, L.P.1
Yang, R.2
Korn, B.3
Burwinkel, B.4
Brenner, H.5
-
11
-
-
84855839546
-
Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers
-
Monick, M. M. et al. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. Am. J. Med. Genet. B 159, 141-151 (2012).
-
(2012)
Am. J. Med. Genet. B
, vol.159
, pp. 141-151
-
-
Monick, M.M.1
-
12
-
-
84868206265
-
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
-
Landan, G. et al. Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues. Nature Genet. 44, 1207-1214 (2012).
-
(2012)
Nature Genet
, vol.44
, pp. 1207-1214
-
-
Landan, G.1
-
13
-
-
76549135113
-
Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease
-
Feinberg, A. P. & Irizarry, R. A. Evolution in health and medicine Sackler colloquium: stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc. Natl Acad. Sci. USA 107 (Suppl. 1), 1757-1764 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, Issue.SUPPL. 1
, pp. 1757-1764
-
-
Feinberg, A.P.1
Irizarry, R.A.2
-
14
-
-
84865344330
-
Stochastic choice of allelic expression in human neural stem cells
-
Jeffries, A. R. et al. Stochastic choice of allelic expression in human neural stem cells. Stem Cells 30, 1938-1947 (2012).
-
(2012)
Stem Cells
, vol.30
, pp. 1938-1947
-
-
Jeffries, A.R.1
-
15
-
-
79961180449
-
Epidemiology epigenetics and the 'gloomy prospect': Embracing randomness in population health research and practice
-
Smith, G. D. Epidemiology, epigenetics and the 'gloomy prospect': embracing randomness in population health research and practice. Int. J. Epidemiol. 40, 537-562 (2011).
-
(2011)
Int. J. Epidemiol
, vol.40
, pp. 537-562
-
-
Smith, G.D.1
-
16
-
-
77950675978
-
Developmental origins of metabolic disease: Life course and intergenerational perspectives
-
Godfrey, K. M., Gluckman, P. D. & Hanson, M. A. Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol. Metab. 21, 199-205 (2010).
-
(2010)
Trends Endocrinol. Metab
, vol.21
, pp. 199-205
-
-
Godfrey, K.M.1
Gluckman, P.D.2
Hanson, M.A.3
-
17
-
-
3342979802
-
Developmental plasticity and human health
-
DOI 10.1038/nature02725
-
Bateson, P. et al. Developmental plasticity and human health. Nature 430, 419-421 (2004). (Pubitemid 38987896)
-
(2004)
Nature
, vol.430
, Issue.6998
, pp. 419-421
-
-
Bateson, P.1
Barker, D.2
Clutton-Brock, T.3
Deb, D.4
D'Udine, B.5
Foley, R.A.6
Gluckman, P.7
Godfrey, K.8
Kirkwood, T.9
Lahr, M.M.10
McNamara, J.11
Metcalfe, N.B.12
Monaghan, P.13
Spencer, H.G.14
Sultan, S.E.15
-
18
-
-
70349999407
-
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
-
Tobi, E. W. et al. DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum. Mol. Genet. 18, 4046-4053 (2009).
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 4046-4053
-
-
Tobi, E.W.1
-
19
-
-
84859226938
-
An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity
-
Kuehnen, P. et al. An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity. PLoS Genet. 8, e1002543 (2012).
-
(2012)
PLoS Genet
, vol.8
-
-
Kuehnen, P.1
-
20
-
-
84865214259
-
The continuing value of twin studies in the omics era
-
van Dongen, J., Slagboom, P. E., Draisma, H. H., Martin, N. G. & Boomsma, D. I. The continuing value of twin studies in the omics era. Nature Rev. Genet. 13, 640-653 (2012).
-
(2012)
Nature Rev. Genet
, vol.13
, pp. 640-653
-
-
Van Dongen, J.1
Slagboom, P.E.2
Draisma, H.H.3
Martin, N.G.4
Boomsma, D.I.5
-
21
-
-
33847095134
-
Complex disease, gender and epigenetics
-
DOI 10.1080/07853890600989211, PII 768564362
-
Kaminsky, Z., Wang, S. C. & Petronis, A. Complex disease, gender and epigenetics. Ann. Med. 38, 530-544 (2006). (Pubitemid 46292018)
-
(2006)
Annals of Medicine
, vol.38
, Issue.8
, pp. 530-544
-
-
Kaminsky, Z.1
Wang, S.-C.2
Petronis, A.3
-
22
-
-
72449122779
-
Parental origin of sequence variants associated with complex diseases
-
Kong, A. et al. Parental origin of sequence variants associated with complex diseases. Nature 462, 868-874 (2009).
-
(2009)
Nature
, vol.462
, pp. 868-874
-
-
Kong, A.1
-
23
-
-
84858681550
-
Commentary: The seven plagues of epigenetic epidemiology
-
Heijmans, B. T. & Mill, J. Commentary: the seven plagues of epigenetic epidemiology. Int. J. Epidemiol. 41, 74-78 (2012).
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 74-78
-
-
Heijmans, B.T.1
Mill, J.2
-
24
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
The Wellcome Trust Case Control Consortium
-
The Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
25
-
-
84860572791
-
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
-
Bell, J. T. et al. Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet. 8, e1002629 (2012).
-
(2012)
PLoS Genet
, vol.8
-
-
Bell, J.T.1
-
26
-
-
84860637797
-
DNA methylation arrays as surrogate measures of cell mixture distribution
-
Houseman, E. A. et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics 13, 86 (2012).
-
(2012)
BMC Bioinformatics
, vol.13
, pp. 86
-
-
Houseman, E.A.1
-
27
-
-
77956873627
-
Tackling the widespread and critical impact of batch effects in high-throughput data
-
Leek, J. T. et al. Tackling the widespread and critical impact of batch effects in high-throughput data. Nature Rev. Genet. 11, 733-739 (2010).
-
(2010)
Nature Rev. Genet
, vol.11
, pp. 733-739
-
-
Leek, J.T.1
-
28
-
-
84858648623
-
Two-step epigenetic Mendelian randomization: A strategy for establishing the causal role of epigenetic processes in pathways to disease
-
Relton, C. L. & Davey Smith, G. Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease. Int. J. Epidemiol. 41, 161-176 (2012).
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 161-176
-
-
Relton, C.L.1
Davey Smith, G.2
-
29
-
-
84856297910
-
Current status and future prospects for epigenetic psychopharmacology
-
Boks, M. P. et al. Current status and future prospects for epigenetic psychopharmacology. Epigenetics 7, 20-28 (2012).
-
(2012)
Epigenetics
, vol.7
, pp. 20-28
-
-
Boks, M.P.1
-
30
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird, P. W. Principles and challenges of genomewide DNA methylation analysis. Nature Rev. Genet. 11, 191-203 (2010).
-
(2010)
Nature Rev. Genet
, vol.11
, pp. 191-203
-
-
Laird P., .W.1
-
31
-
-
79958754527
-
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
-
Sandoval, J. et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics 6, 692-702 (2011).
-
(2011)
Epigenetics
, vol.6
, pp. 692-702
-
-
Sandoval, J.1
-
32
-
-
84863469546
-
The role of longitudinal cohort studies in epigenetic epidemiology: Challenges and opportunities
-
Ng, J. W. et al. The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. Genome Biol. 13, 246 (2012).
-
(2012)
Genome Biol
, vol.13
, pp. 246
-
-
Ng, J.W.1
-
33
-
-
84858055958
-
Acute exercise remodels promoter methylation in human skeletal muscle
-
Barres, R. et al. Acute exercise remodels promoter methylation in human skeletal muscle. Cell. Metab. 15, 405-411 (2012).
-
(2012)
Cell. Metab
, vol.15
, pp. 405-411
-
-
Barres, R.1
-
34
-
-
84864610761
-
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence
-
Gordon, L. et al. Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res. 22, 1395-1406 (2012).
-
(2012)
Genome Res
, vol.22
, pp. 1395-1406
-
-
Gordon, L.1
-
35
-
-
84859222932
-
Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: A study of a unique resource in the Gambia
-
Khulan, B. et al. Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in the epigenome: a study of a unique resource in the Gambia. Hum. Mol. Genet. 21, 2086-2101 (2012).
-
(2012)
Hum. Mol. Genet
, vol.21
, pp. 2086-2101
-
-
Khulan, B.1
-
36
-
-
84871688621
-
Analysing and interpreting DNA methylation data
-
Bock, C. Analysing and interpreting DNA methylation data. Nature Rev. Genet. 13, 705-719 (2012).
-
(2012)
Nature Rev. Genet
, vol.13
, pp. 705-719
-
-
Bock, C.1
-
37
-
-
0031617319
-
-
(eds Chadwick, D. K. & Cardew, G.)
-
Riggs, A. D., Xiong, Z., Wang, L. & LeBon, J. M. in Novartis Foundation Symposium 214 - Epigenetics (eds Chadwick, D. K. & Cardew, G.) 214-232 (1998).
-
(1998)
Novartis Foundation Symposium 214 - Epigenetics
, pp. 214-232
-
-
Riggs, A.D.1
Xiong, Z.2
Wang, L.3
Lebon, J.M.4
-
38
-
-
84862210732
-
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood
-
Davies, M. N. et al. Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol. 13, R43 (2012).
-
(2012)
Genome Biol
, vol.13
-
-
Davies, M.N.1
-
39
-
-
79551616746
-
Epigenetics: Prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage
-
Vanhees, K. et al. Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage. FASEB J. 25, 797-807 (2011).
-
(2011)
FASEB J
, vol.25
, pp. 797-807
-
-
Vanhees, K.1
-
40
-
-
84864019015
-
Epigenetic variation during the adult lifespan: Cross-sectional and longitudinal data on monozygotic twin pairs
-
Talens, R. P. et al. Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell 11, 694-703 (2012).
-
(2012)
Aging Cell
, vol.11
, pp. 694-703
-
-
Talens, R.P.1
-
41
-
-
84863386102
-
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies
-
Jaffe, A. E. et al. Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int. J. Epidemiol. 41, 200-209 (2012).
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 200-209
-
-
Jaffe, A.E.1
-
42
-
-
84863366233
-
DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth
-
Lee, H. et al. DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. Int. J. Epidemiol. 41, 188-199 (2012).
-
(2012)
Int. J. Epidemiol
, vol.41
, pp. 188-199
-
-
Lee, H.1
-
43
-
-
84865836579
-
Widespread plasticity in CTCF occupancy linked to DNA methylation
-
Wang, H. et al. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res. 22, 1680-1688 (2012).
-
(2012)
Genome Res
, vol.22
, pp. 1680-1688
-
-
Wang, H.1
-
44
-
-
38849090146
-
The thrifty epigenotype: An acquired and heritable predisposition for obesity and diabetes?
-
DOI 10.1002/bies.20700
-
Stoger, R. The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes? Bioessays 30, 156-166 (2008). (Pubitemid 351196950)
-
(2008)
BioEssays
, vol.30
, Issue.2
, pp. 156-166
-
-
Stoger, R.1
-
45
-
-
84866868744
-
Aging effects on DNA methylation modules in human brain and blood tissue
-
Horvath, S. et al. Aging effects on DNA methylation modules in human brain and blood tissue. Genome Biol. 13, R97 (2012).
-
(2012)
Genome Biol
, vol.13
-
-
Horvath, S.1
-
46
-
-
33847304609
-
Gene body-specific methylation on the active X chromosome
-
DOI 10.1126/science.1136352
-
Hellman, A. & Chess, A. Gene body-specific methylation on the active X chromosome. Science 315, 1141-1143 (2007). (Pubitemid 46328027)
-
(2007)
Science
, vol.315
, Issue.5815
, pp. 1141-1143
-
-
Hellman, A.1
Chess, A.2
-
47
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea, A. K. et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 466, 253-257 (2010).
-
(2010)
Nature
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
-
48
-
-
84877108379
-
DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure
-
Gelfman, S., Cohen, N., Yearim, A. & Ast, G. DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon-intron structure. Genome Res. 23, 789-799 (2013).
-
(2013)
Genome Res
, vol.23
, pp. 789-799
-
-
Gelfman, S.1
Cohen, N.2
Yearim, A.3
Ast, G.4
-
49
-
-
84874816208
-
DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes
-
Aran, D., Sabato, S. & Hellman, A. DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes. Genome Biol. 14, R21 (2013).
-
(2013)
Genome Biol
, vol.14
-
-
Aran, D.1
Sabato, S.2
Hellman, A.3
-
50
-
-
38449102144
-
Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
-
Klug, M. & Rehli, M. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 1, 127-130 (2006).
-
(2006)
Epigenetics
, vol.1
, pp. 127-130
-
-
Klug, M.1
Rehli, M.2
-
51
-
-
79955970344
-
Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
-
Bocker, M. T. et al. Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood 117, e182-189 (2011).
-
(2011)
Blood
, vol.117
-
-
Bocker, M.T.1
-
52
-
-
78449231434
-
Gestational low protein diet in the rat mediates Igf2 gene expression in male offspring via altered hepatic DNA methylation
-
Gong, L., Pan, Y. X. & Chen, H. Gestational low protein diet in the rat mediates Igf2 gene expression in male offspring via altered hepatic DNA methylation. Epigenetics 5, 619-626 (2010).
-
(2010)
Epigenetics
, vol.5
, pp. 619-626
-
-
Gong, L.1
Pan, Y.X.2
Chen, H.3
-
53
-
-
77957940722
-
The NIH roadmap epigenomics mapping consortium
-
Bernstein, B. E. et al. The NIH Roadmap Epigenomics Mapping Consortium. Nature Biotech. 28, 1045-1048 (2010).
-
(2010)
Nature Biotech
, vol.28
, pp. 1045-1048
-
-
Bernstein, B.E.1
-
54
-
-
76249121728
-
Time for the epigenome
-
[No authors listed.]
-
[No authors listed.] Time for the epigenome. Nature 463, 587 (2010).
-
(2010)
Nature
, vol.463
, pp. 587
-
-
-
55
-
-
81855183787
-
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
-
Dempster, E. L. et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum. Mol. Genet. 20, 4786-4796 (2011).
-
(2011)
Hum. Mol. Genet
, vol.20
, pp. 4786-4796
-
-
Dempster, E.L.1
-
56
-
-
84875700729
-
A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
-
Guintivano, J., Aryee, M. J. & Kaminsky, Z. A. A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics 8, 290-302 (2013).
-
(2013)
Epigenetics
, vol.8
, pp. 290-302
-
-
Guintivano, J.1
Aryee, M.J.2
Kaminsky, Z.A.3
-
57
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
Liu, Y. et al. Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nature Biotech. 31, 142-147 (2013).
-
(2013)
Nature Biotech
, vol.31
, pp. 142-147
-
-
Liu, Y.1
-
58
-
-
84874175265
-
Transgenerational epigenetic inheritance: How important is it?
-
Grossniklaus, U., Kelly, B., Ferguson-Smith, A. C., Pembrey, M. & Lindquist, S. Transgenerational epigenetic inheritance: how important is it? Nature Rev. Genet. 14, 228-235 (2013).
-
(2013)
Nature Rev. Genet
, vol.14
, pp. 228-235
-
-
Grossniklaus, U.1
Kelly, B.2
Ferguson-Smith, A.C.3
Pembrey, M.4
Lindquist, S.5
-
59
-
-
78650061153
-
Transgenerational epigenetic inheritance: More questions than answers
-
Daxinger, L. & Whitelaw, E. Transgenerational epigenetic inheritance: more questions than answers. Genome Res. 20, 1623-1628 (2010).
-
(2010)
Genome Res
, vol.20
, pp. 1623-1628
-
-
Daxinger, L.1
Whitelaw, E.2
-
60
-
-
84857189974
-
Understanding transgenerational epigenetic inheritance via the gametes in mammals
-
Daxinger, L. & Whitelaw, E. Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nature Rev. Genet. 13, 153-162 (2012).
-
(2012)
Nature Rev. Genet
, vol.13
, pp. 153-162
-
-
Daxinger, L.1
Whitelaw, E.2
-
61
-
-
78649929055
-
Male-line transgenerational responses in humans
-
Pembrey, M. E. Male-line transgenerational responses in humans. Hum. Fertil. 13, 268-271 (2010).
-
(2010)
Hum. Fertil
, vol.13
, pp. 268-271
-
-
Pembrey, M.E.1
-
62
-
-
34250781054
-
Transgenerational response to nutrition, early life circumstances and longevity
-
DOI 10.1038/sj.ejhg.5201832, PII 5201832
-
Kaati, G., Bygren, L. O., Pembrey, M. & Sjostrom, M. Transgenerational response to nutrition, early life circumstances and longevity. Eur. J. Hum. Genet. 15, 784-790 (2007). (Pubitemid 46965412)
-
(2007)
European Journal of Human Genetics
, vol.15
, Issue.7
, pp. 784-790
-
-
Kaati, G.1
Bygren, L.O.2
Pembrey, M.3
Sjostrom, M.4
-
63
-
-
38349100549
-
Epigenetic events in mammalian germ-cell development: Reprogramming and beyond
-
Sasaki, H. & Matsui, Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nature Rev. Genet. 9, 129-140 (2008).
-
(2008)
Nature Rev. Genet
, vol.9
, pp. 129-140
-
-
Sasaki, H.1
Matsui, Y.2
-
64
-
-
3342989681
-
Epigenetic programming by maternal behavior
-
DOI 10.1038/nn1276
-
Weaver, I. C. et al. Epigenetic programming by maternal behavior. Nature Neurosci. 7, 847-854 (2004). (Pubitemid 38989508)
-
(2004)
Nature Neuroscience
, vol.7
, Issue.8
, pp. 847-854
-
-
Weaver, I.C.G.1
Cervoni, N.2
Champagne, F.A.3
D'Alessio, A.C.4
Sharma, S.5
Seckl, J.R.6
Dymov, S.7
Szyf, M.8
Meaney, M.J.9
-
65
-
-
84861909717
-
Epigenetic transgenerational inheritance of altered stress responses
-
Crews, D. et al. Epigenetic transgenerational inheritance of altered stress responses. Proc. Natl Acad. Sci. USA 109, 9143-9148 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 9143-9148
-
-
Crews, D.1
-
66
-
-
84871702441
-
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
-
Seisenberger, S. et al. The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol. Cell 48, 849-862 (2012).
-
(2012)
Mol. Cell
, vol.48
, pp. 849-862
-
-
Seisenberger, S.1
-
67
-
-
78649459828
-
Targets and dynamics of promoter DNA methylation during early mouse development
-
Borgel, J. et al. Targets and dynamics of promoter DNA methylation during early mouse development. Nature Genet. 42, 1093-1100 (2010).
-
(2010)
Nature Genet
, vol.42
, pp. 1093-1100
-
-
Borgel, J.1
-
68
-
-
70349326221
-
Epigenetic inheritance and the missing heritability problem
-
Slatkin, M. Epigenetic inheritance and the missing heritability problem. Genetics 182, 845-850 (2009).
-
(2009)
Genetics
, vol.182
, pp. 845-850
-
-
Slatkin, M.1
-
69
-
-
76049126281
-
Allelic skewing of DNA methylation is widespread across the genome
-
Schalkwyk, L. C. et al. Allelic skewing of DNA methylation is widespread across the genome. Am. J. Hum. Genet. 86, 196-212 (2010).
-
(2010)
Am. J. Hum. Genet
, vol.86
, pp. 196-212
-
-
Schalkwyk, L.C.1
-
70
-
-
84884212298
-
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants
-
Gamazon, E. R. et al. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psych. 18, 340-346 (2012).
-
(2012)
Mol Psych
, vol.18
, pp. 340-346
-
-
Gamazon, E.R.1
-
71
-
-
77957911410
-
Allele-specific methylation in the human genome: Implications for genetic studies of complex disease
-
Meaburn, E. L., Schalkwyk, L. C. & Mill, J. Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics 5, 578-582 (2010).
-
(2010)
Epigenetics
, vol.5
, pp. 578-582
-
-
Meaburn, E.L.1
Schalkwyk, L.C.2
Mill, J.3
-
73
-
-
35548941189
-
Epigenetic epidemiology of the developmental origins hypothesis
-
DOI 10.1146/annurev.nutr.27.061406.093705
-
Waterland, R. A. & Michels, K. B. Epigenetic epidemiology of the developmental origins hypothesis. Annu. Rev. Nutr. 27, 363-388 (2007). (Pubitemid 351373362)
-
(2007)
Annual Review of Nutrition
, vol.27
, pp. 363-388
-
-
Waterland, R.A.1
Michels, K.B.2
-
74
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou, V. W., Goren, A. & Bernstein, B. E. Charting histone modifications and the functional organization of mammalian genomes. Nature Rev. Genet. 12, 7-18 (2011).
-
(2011)
Nature Rev. Genet
, vol.12
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
75
-
-
84865061978
-
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase
-
Raiber, E. A. et al. Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol. 13, R69 (2012).
-
(2012)
Genome Biol
, vol.13
-
-
Raiber, E.A.1
-
76
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu, M. et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 149, 1368-1380 (2012).
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
-
77
-
-
77954061853
-
Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA
-
Nestor, C., Ruzov, A., Meehan, R. & Dunican, D. Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA. Biotechniques 48, 317-319 (2010).
-
(2010)
Biotechniques
, vol.48
, pp. 317-319
-
-
Nestor, C.1
Ruzov, A.2
Meehan, R.3
Dunican, D.4
-
78
-
-
0043093697
-
Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
-
DOI 10.1128/MCB.23.15.5293-5300.2003
-
Waterland, R. A. & Jirtle, R. L. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol. Cell. Biol. 23, 5293-5300 (2003). (Pubitemid 36950884)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.15
, pp. 5293-5300
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
79
-
-
77956481228
-
Tissue-specific dysregulation of DNA methylation in aging
-
Thompson, R. F. et al. Tissue-specific dysregulation of DNA methylation in aging. Aging Cell 9, 506-518 (2010).
-
(2010)
Aging Cell
, vol.9
, pp. 506-518
-
-
Thompson, R.F.1
-
80
-
-
37049020951
-
Cohort profile: The Dutch Hunger Winter families study
-
DOI 10.1093/ije/dym126
-
Lumey, L. H. et al. Cohort profile: the Dutch Hunger Winter Families Study. Int. J. Epidemiol. 36, 1196-1204 (2007). (Pubitemid 350244404)
-
(2007)
International Journal of Epidemiology
, vol.36
, Issue.6
, pp. 1196-1204
-
-
Lumey, L.H.1
Stein, A.D.2
Kahn, H.S.3
Van Der Pal-de Bruin, K.M.4
Blauw, G.J.5
Zybert, P.A.6
Susser, E.S.7
-
81
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
Heijmans, B. T. et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc. Natl Acad. Sci. USA 105, 17046-17049 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
-
82
-
-
84861605111
-
Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19
-
Tobi, E. W. et al. Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS ONE 7, e37933 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Tobi, E.W.1
-
83
-
-
84875619270
-
Cohort profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
-
Fraser, A. et al. Cohort profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. Int. J. Epidemiol. 42, 97-110 (2013).
-
(2013)
Int. J. Epidemiol
, vol.42
, pp. 97-110
-
-
Fraser, A.1
-
84
-
-
84863012079
-
Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass
-
Groom, A. et al. Postnatal growth and DNA methylation are associated with differential gene expression of the TACSTD2 gene and childhood fat mass. Diabetes 61, 391-400 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 391-400
-
-
Groom, A.1
-
85
-
-
84859586172
-
DNA methylation patterns in cord blood DNA and body size in childhood
-
Relton, C. L. et al. DNA methylation patterns in cord blood DNA and body size in childhood. PLoS ONE 7, e31821 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Relton, C.L.1
-
86
-
-
77957353569
-
A longitudinal study of epigenetic variation in twins
-
Wong, C. C. et al. A longitudinal study of epigenetic variation in twins. Epigenetics 5, 516-526 (2010).
-
(2010)
Epigenetics
, vol.5
, pp. 516-526
-
-
Wong, C.C.1
-
87
-
-
84897111264
-
Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits
-
Wong, C. C. et al. Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol. Psych. http://dx.doi.org/10.1038/mp.2013.41 (2013).
-
(2013)
Mol. Psych
-
-
Wong, C.C.1
-
88
-
-
84872132897
-
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
-
Heyn, H. et al. DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker. Carcinogenesis http://dx.doi.org/10.1093/carcin/bgs321 (2012).
-
(2012)
Carcinogenesis
-
-
Heyn, H.1
-
89
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
Javierre, B. M. et al. Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res. 20, 170-179 (2010).
-
(2010)
Genome Res
, vol.20
, pp. 170-179
-
-
Javierre, B.M.1
-
90
-
-
68949096744
-
Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease
-
Mastroeni, D., McKee, A., Grover, A., Rogers, J. & Coleman, P. D. Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease. PLoS ONE 4, e6617 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Mastroeni, D.1
McKee, A.2
Grover, A.3
Rogers, J.4
Coleman, P.D.5
-
91
-
-
80053457972
-
Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis
-
Rakyan, V. K. et al. Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis. PLoS Genet. 7, e1002300 (2011).
-
(2011)
PLoS Genet
, vol.7
-
-
Rakyan, V.K.1
-
92
-
-
84873909354
-
The Peri/Postnatal Epigenetic Twins Study (PETS)
-
Loke, Y. J. et al. The Peri/Postnatal Epigenetic Twins Study (PETS). Twin Res. Hum. Genet. 16, 13-20 (2013).
-
(2013)
Twin Res. Hum. Genet
, vol.16
, pp. 13-20
-
-
Loke, Y.J.1
-
93
-
-
32144452906
-
Cohort profile: The Southampton Women's Survey
-
DOI 10.1093/ije/dyi202
-
Inskip, H. M. et al. Cohort profile: the Southampton women's survey. Int. J. Epidemiol. 35, 42-48 (2006). (Pubitemid 43205441)
-
(2006)
International Journal of Epidemiology
, vol.35
, Issue.1
, pp. 42-48
-
-
Inskip, H.M.1
Godfrey, K.M.2
Robinson, S.M.3
Law, C.M.4
Barker, D.J.P.5
Cooper, C.6
-
94
-
-
79957834770
-
Epigenetic gene promoter methylation at birth is associated with child's later adiposity
-
Godfrey, K. M. et al. Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes 60, 1528-1534 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 1528-1534
-
-
Godfrey, K.M.1
-
95
-
-
0032870739
-
The Danish in vitro fertilisation (IVF) register
-
Andersen, A. N., Westergaard, H. B. & Olsen, J. The Danish in vitro fertilisation (IVF) register. Dan. Med. Bull. 46, 357-360 (1999). (Pubitemid 29439150)
-
(1999)
Danish Medical Bulletin
, vol.46
, Issue.4
, pp. 357-360
-
-
Andersen, A.N.1
Westergaard, H.B.2
Olsen, J.3
-
96
-
-
18744381061
-
Imprinting diseases and IVF: Danish National IVF cohort study
-
DOI 10.1093/humrep/deh714
-
Lidegaard, O., Pinborg, A. & Andersen, A. N. Imprinting diseases and IVF: Danish National IVF cohort study. Hum. Reprod. 20, 950-954 (2005). (Pubitemid 40674198)
-
(2005)
Human Reproduction
, vol.20
, Issue.4
, pp. 950-954
-
-
Lidegaard, O.1
Pinborg, A.2
Andersen, A.N.3
-
97
-
-
78650446334
-
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals
-
Carone, B. R. et al. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell 143, 1084-1096 (2010).
-
(2010)
Cell
, vol.143
, pp. 1084-1096
-
-
Carone, B.R.1
-
98
-
-
84868103364
-
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
-
Beyan, H. et al. Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res. 22, 2138-2145 (2012).
-
(2012)
Genome Res
, vol.22
, pp. 2138-2145
-
-
Beyan, H.1
|