High salt promotes autoimmunity by TET2-induced DNA demethylation and driving the differentiation of Tfh cells

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Wu, Haijing ^a   Huang, Xin ^a   Qiu, Hong ^a   Zhao, Ming ^a   Liao, Wei ^a   Yuan, Shuguang ^a   Xie, Yubing ^b   Dai, Yong ^c   Chang, Christopher ^d   Yoshimura, Akihiko ^e   Lu, Qianjin ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Changsha Blood Center   (China)

^c SHENZHEN PEOPLE'S HOSPITAL   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; ONCOPROTEIN; STAT5 PROTEIN; TET2 PROTEIN, MOUSE;

ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOIMMUNITY; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL POLARITY; CYTOLOGY; DNA DEMETHYLATION; DRUG EFFECTS; GENETICS; HELPER CELL; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; MORTALITY; MOUSE; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE; PATHOLOGY; PHARMACOLOGY; RNA INTERFERENCE; SALT INTAKE; SURVIVAL RATE; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL POLARITY; CELLS, CULTURED; DNA DEMETHYLATION; DNA-BINDING PROTEINS; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MAP KINASE KINASE KINASE 1; MICE; MICE, INBRED BALB C; MICE, INBRED MRL LPR; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; SODIUM CHLORIDE, DIETARY; STAT5 TRANSCRIPTION FACTOR; SURVIVAL RATE; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84976274975     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep28065     Document Type: Article

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