Mesenchymal stem cells deliver exogenous MicroRNA-let7c via exosomes to attenuate renal fibrosis

Molecular Therapy

Volumn 24, Issue 7, 2016, Pages 1290-1301

  Wang, Bo ^a   Yao, Kevin ^a   Huuskes, Brooke M ^a   Shen, Hsin Hui ^a   Zhuang, Junli ^a   Godson, Catherine ^b   Brennan, Eoin P ^b   Wilkinson Berka, Jennifer L ^a   Wise, Andrea F ^a   Ricardo, Sharon D ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1 ALPHA 1; COLLAGEN TYPE 4; COLLAGEN TYPE 4 ALPHA 1; FIBRONECTIN; GELATINASE B; MICRORNA; MICRORNA LET7C; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ACTIN; COLLAGEN; EPIDERMAL GROWTH FACTOR RECEPTOR;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BIOLUMINESCENCE IMAGING; CELL COMMUNICATION; CELL ENGINEERING; CELL HOMING; COCULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; EPITHELIUM CELL; EXOSOME; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMAGING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULAR EPITHELIAL CELL; MALE; MESENCHYMAL STEM CELL; MORPHOMETRICS; NONHUMAN; PROTEIN EXPRESSION; RAT; UPREGULATION; VIRAL GENE DELIVERY SYSTEM; ANIMAL; DISEASE MODEL; FIBROSIS; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; GENETICS; KIDNEY DISEASES; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ACTINS; ANIMALS; BIOLOGICAL TRANSPORT; CELL ENGINEERING; COLLAGEN; DISEASE MODELS, ANIMAL; EXOSOMES; EXTRACELLULAR VESICLES; FIBROSIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; HUMANS; KIDNEY DISEASES; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSDUCTION, GENETIC;

EID: 84975267334     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2016.90     Document Type: Article

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