A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans

Cell Death and Disease

Volumn 6, Issue 10, 2015, Pages

  Martinez, B A ^a   Kim, H ^a   Ray, A ^a   Caldwell, G A ^a,b   Caldwell, K A ^a,b  

^a UNIVERSITY OF ALABAMA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; ANTIOXIDANT; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CAENORHABDITIS ELEGANS PROTEIN; GLUTATHIONE; PINK 1 PROTEIN; PROTEASOME; UBIQUITIN E3 LIGASE PDR 1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BACTERIAL TOXIN; PINK1 PROTEIN, C ELEGANS; PROTEIN SERINE THREONINE KINASE;

ALLELE; ARTICLE; BACTERIAL GENETICS; BACTERIAL METABOLISM; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FLUORESCENCE MICROSCOPY; GENETIC BACKGROUND; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; PROTEOSTASIS DEFICIENCY; STREPTOMYCES VENEZUELAE; XENOPHAGY; ANIMAL; AUTOPHAGY; CHEMISTRY; DEGENERATIVE DISEASE; DRUG EFFECTS; ENZYMOLOGY; HOMEOSTASIS; METABOLISM; MICROBIOLOGY; MITOCHONDRION; NERVE CELL; PHYSIOLOGY; STREPTOMYCES;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; BACTERIAL TOXINS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GLUTATHIONE; HOMEOSTASIS; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTEOSTASIS DEFICIENCIES; STREPTOMYCES;

EID: 84975248873     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.270     Document Type: Article

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