The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models

Cell Metabolism

Volumn 20, Issue 1, 2014, Pages 145-157

  Knight, Adam L ^a,e,f   Yan, Xiaohui ^a   Hamamichi, Shusei ^a   Ajjuri, Rami R ^a   Mazzulli, Joseph R ^c,h   Zhang, Mike W ^a   Daigle, J Gavin ^a,g   Zhang, Siyuan ^a   Borom, Akeem R ^a   Roberts, Lindsay R ^a   Lee, S Kyle ^a   DeLeon, Susan M ^a   Viollet Djelassi, Coralie ^d   Krainc, Dimitri ^c,h   O'Donnell, Janis M ^a   Caldwell, Kim A ^a,b   Caldwell, Guy A ^a,b  

^a UNIVERSITY OF ALABAMA   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e BABRAHAM INSTITUTE   (United Kingdom)

^f NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^g LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; GLUCOSE 6 PHOSPHATE ISOMERASE; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; GLYCOLYTIC ENZYME; GPI ENZYME; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; CHICO PROTEIN, DROSOPHILA; CYTOKINE; DAF-16 PROTEIN, C ELEGANS; DAF-2 PROTEIN, C ELEGANS; DROSOPHILA PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; GLUCOSE; GPI1 PROTEIN, MOUSE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; SMALL INTERFERING RNA; SOMATOMEDIN C; TRANSCRIPTION FACTOR;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DROSOPHILA; ENERGY YIELD; GENETIC ASSOCIATION; GENETIC CROSS; GENETIC SCREENING; GLUCOSE METABOLISM; HUMAN; MALE; MOUSE; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; NUCLEIC ACID METABOLISM; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN HOMEOSTASIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WORM; ANIMAL TISSUE; CELL PROTECTION; DOPAMINERGIC NERVE CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NEUROPROTECTION; PHENOTYPE; PROTEIN FOLDING; RNA INTERFERENCE; AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; CYTOLOGY; DISEASE MODEL; GENETICS; GLYCOLYSIS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS;

AGING; ALPHA-SYNUCLEIN; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; DROSOPHILA; DROSOPHILA PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; GLUCOSE-6-PHOSPHATE ISOMERASE; GLYCOLYSIS; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; PARKINSON DISEASE; RECEPTOR, INSULIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84904035981     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.04.017     Document Type: Article

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