The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration

Biochemical Journal

Volumn 473, Issue 6, 2016, Pages 733-742

  Chen, Kelan ^a,b   Czabotar, Peter E ^a,b   Blewitt, Marnie E ^a,b   Murphy, James M ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Coiled coil; Dimer; Facioscapulohumeral dystrophy (fshd); Protocadherin; Structural maintenance of chromosomes (smc); X inactivation.

Indexed keywords

HOMODIMER; MONOMER; PROTEIN; SMCHD1 PROTEIN; UNCLASSIFIED DRUG; NONHISTONE PROTEIN; RECOMBINANT PROTEIN; SMCHD1 PROTEIN, MOUSE;

ARTICLE; CHROMATIN; CONTROLLED STUDY; EPIGENETIC REPRESSION; FEMALE; GENE SILENCING; HINGE REGION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; ANIMAL; CHEMICAL STRUCTURE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; IMMUNOPRECIPITATION; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CHROMOSOMAL PROTEINS, NON-HISTONE; EPIGENETIC REPRESSION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MICE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84975166639     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20151049     Document Type: Article

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