MTB, the murine homolog of condensin II subunit CAP-G2, represses transcription and promotes erythroid cell differentiation

Leukemia

Volumn 20, Issue 7, 2006, Pages 1261-1269

  Xu, Y ^a   Leung, C G ^a   Lee, D C ^b   Kennedy, B K ^b   Crispino, J D ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Condensin; Erythropoiesis; Repression; SCL; Transcription

Indexed keywords

CHROMOSOME PROTEIN; CONDENSIN; HELIX LOOP HELIX PROTEIN; PROTEIN CAP G2; PROTEIN MTB; PROTEIN SUBUNIT; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CHROMOSOME CONDENSATION; CHROMOSOME STRUCTURE; CONTROLLED STUDY; ERYTHROID CELL; ERYTHROPOIESIS; GENE OVEREXPRESSION; GENETIC CODE; HEMATOPOIETIC STEM CELL; IMMUNOFLUORESCENCE TEST; IMMUNOPRECIPITATION; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 33745212722     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404252     Document Type: Article

References (27)

1. Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T. Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells. Cell 2003; 115: 109-121.
2. Legagneux V, Cubizolles F, Watrin E. Multiple roles of condensins: A complex story. Biol Cell 2004; 96: 201-213.
3. Hirano T. Condensins: Organizing and segregating the genome. Curr Biol 2005; 15: R265-R275.
4. Chuang PT, Albertson DG, Meyer BJ. DPY-27: A chromosome condensation protein homolog that regulates C. elegans dosage compensation through association with the X chromosome. Cell 1994; 79: 459-474.
5. Lieb JD, Albrecht MR, Chuang PT, Meyer BJ. MIX-1: An essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation. Cell 1998; 92: 265-277.
6. Lupo R, Breiling A, Bianchi ME, Orlando V. Drosophila chromosome condensation proteins Topoisomerase II and Barren colocalize with Polycomb and maintain Fab-7 PRE silencing. Mol Cell 2001; 7: 127-136.
7. Aono N, Sutani T, Tomonaga T, Mochida S, Yanagida M. Cnd2 has dual roles in mitotic condensation and interphase. Nature 2002; 417: 197-202.
8. Grigoryev SA, Woodcock CL. Stage-specific expression and localization of MENT, a nuclear protein associated with chromatin condensation in terminally differentiating avian erythroid cells. Exp Cell Res 1993; 206: 335-343.
9. Grigoryev SA, Solovieva VO, Spirin KS, Krasheninnikov IA. A novel nonhistone protein (MENT) promotes nuclear collapse at the terminal stage of avian erythropoiesis. Exp Cell Res 1992; 198: 268-275.
10. Smith ED, Xu Y, Tomson BN, Leung CG, Fujiwara Y, Orkin SH et al. More than blood, a novel gene required for mammalian postimplantation development. Mol Cell Biol 2004; 24: 1168-1173.
11. Lecuyer E, Hoang T. SCL: From the origin of hematopoiesis to stem cells and leukemia. Exp Hematol 2004; 32: 11-24.
12. Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y et al. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature 2003; 421: 547-551.
13. Huang S, Brandt SJ. mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. Mol Cell Biol 2000; 20: 2248-2259.
14. Schuh AH, Tipping AJ, Clark AJ, Hamlett I, Guyot B, Iborra FJ et al. ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis. Mol Cell Biol 2005; 25: 10235-10250.
15. Goardon N, Lambert JA, Rodriguez P, Nissaire P, Herblot S, Thibault P et al. ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. EMBO J 2006; 25: 357-366.
16. Porcher C, Liao EC, Fujiwara Y, Zon LI, Orkin SH. Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development 1999; 126: 4603-4615.
17. Crispino JD, Lodish MB, MacKay JP, Orkin SH. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex. Mol Cell 1999; 3: 219-228.
18. Huang DC, Cory S, Strasser A. Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene 1997; 14: 405-414.
19. Kennedy BK, Liu OW, Dick FA, Dyson N, Harlow E, Vidal M. Histone deacetylase-dependent transcriptional repression by pRB in yeast occurs independently of interaction through the LXCXE binding cleft. Proc Natl Acad Sci USA 2001; 98: 8720-8725.
20. Ryan MP, Jones R, Morse RH. SWI-SNF complex participation in transcriptional activation at a step subsequent to activator binding. Mol Cell Biol 1998; 18: 1774-1782.
21. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Srping Harbor Laboratory Press: New York, 1989, pp 16.66-16.67.
22. Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood 2005; 106: 1223-1231.
23. Ono T, Fang Y, Spector DL, Hirano T. Spatial and temporal regulation of condensins I and II in mitotic chromosome assembly in human cells. Mol Biol Cell 2004; 15: 3296-3308.
24. Hirota T, Gerlich D, Koch B, Ellenberg J, Peters JM. Distinct functions of condensin I and II in mitotic chromosome assembly. J Cell Sci 2004; 117 (Part 26): 6435-6445.
25. Uddin S, Ah-Kang J, Ulaszek J, Mahmud D, Wickrema A. Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells. Proc Natl Acad Sci USA 2004; 101: 147-152.
26. Lecuyer E, Herblot S, Saint-Denis M, Martin R, Begley CG, Porcher C et al. The SCL-complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1. Blood 2002; 100: 2430-2440.
27. Wen J, Huang S, Pack SD, Yu X, Brandt SJ, Noguchi CT. Tal1/SCL binding to pericentromeric DNA represses transcription. J Biol Chem 2005; 280: 12956-12966.