-
1
-
-
0031594639
-
Functions of the BRCA1 and BRCA2 genes
-
9529600 10.1016/S0959-437X(98)80056-7 1:CAS:528:DyaK1cXit1Gmsbc%3D
-
D Bertwistle A Ashworth 1998 Functions of the BRCA1 and BRCA2 genes Curr Opin Genet Dev 8 1 14 20 9529600 10.1016/S0959-437X(98)80056-7 1:CAS:528:DyaK1cXit1Gmsbc%3D
-
(1998)
Curr Opin Genet Dev
, vol.8
, Issue.1
, pp. 14-20
-
-
Bertwistle, D.1
Ashworth, A.2
-
2
-
-
0032441791
-
The genetics of breast cancer susceptibility
-
9928476 10.1146/annurev.genet.32.1.95 1:CAS:528:DyaK1MXjvFWmtQ%3D%3D
-
N Rahman MR Stratton 1998 The genetics of breast cancer susceptibility Annu Rev Genet 32 95 121 9928476 10.1146/annurev.genet.32.1.95 1:CAS:528:DyaK1MXjvFWmtQ%3D%3D
-
(1998)
Annu Rev Genet
, vol.32
, pp. 95-121
-
-
Rahman, N.1
Stratton, M.R.2
-
3
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
10749912 10.1093/jnci/92.7.564 1:CAS:528:DC%2BD3cXivFWqtr8%3D
-
M Esteller JM Silva G Dominguez F Bonilla X Matias-Guiu E Lerma E Bussaglia J Prat IC Harkes EA Repasky E Gabrielson M Schutte SB Baylin JG Herman 2000 Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors J Natl Cancer Inst 92 7 564 569 10749912 10.1093/jnci/92.7.564 1:CAS:528:DC%2BD3cXivFWqtr8%3D
-
(2000)
J Natl Cancer Inst
, vol.92
, Issue.7
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
Bonilla, F.4
Matias-Guiu, X.5
Lerma, E.6
Bussaglia, E.7
Prat, J.8
Harkes, I.C.9
Repasky, E.A.10
Gabrielson, E.11
Schutte, M.12
Baylin, S.B.13
Herman, J.G.14
-
4
-
-
0031874053
-
An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers
-
9699523 10.1002/(SICI)1097-0215(19980821)79:4<334::AID-IJC5>3.0. CO;2-W 1:CAS:528:DyaK1cXltVegsrc%3D
-
J Taylor M Lymboura PE Pace RP A'Hern AJ Desai S Shousha RC Coombes S Ali 1998 An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers Int J Cancer 79 4 334 342 9699523 10.1002/(SICI)1097-0215(19980821)79:4<334::AID-IJC5>3.0. CO;2-W 1:CAS:528:DyaK1cXltVegsrc%3D
-
(1998)
Int J Cancer
, vol.79
, Issue.4
, pp. 334-342
-
-
Taylor, J.1
Lymboura, M.2
Pace, P.E.3
A'Hern, R.P.4
Desai, A.J.5
Shousha, S.6
Coombes, R.C.7
Ali, S.8
-
5
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
17016441 10.1038/sj.onc.1210014 1:CAS:528:DC%2BD2sXjsFSiu7c%3D
-
NC Turner JS Reis-Filho AM Russell RJ Springall K Ryder D Steele K Savage CE Gillett FC Schmitt A Ashworth AN Tutt 2007 BRCA1 dysfunction in sporadic basal-like breast cancer Oncogene 26 14 2126 2132 17016441 10.1038/sj.onc. 1210014 1:CAS:528:DC%2BD2sXjsFSiu7c%3D
-
(2007)
Oncogene
, vol.26
, Issue.14
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
Springall, R.J.4
Ryder, K.5
Steele, D.6
Savage, K.7
Gillett, C.E.8
Schmitt, F.C.9
Ashworth, A.10
Tutt, A.N.11
-
6
-
-
47549090640
-
Estrogen receptor alpha, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers
-
17932744 10.1007/s10549-007-9766-6 1:CAS:528:DC%2BD1cXos1Wnsbk%3D
-
M Wei J Xu J Dignam R Nanda L Sveen J Fackenthal TA Grushko OI Olopade 2008 Estrogen receptor alpha, BRCA1, and FANCF promoter methylation occur in distinct subsets of sporadic breast cancers Breast Cancer Res Treat 111 1 113 120 17932744 10.1007/s10549-007-9766-6 1:CAS:528:DC%2BD1cXos1Wnsbk%3D
-
(2008)
Breast Cancer Res Treat
, vol.111
, Issue.1
, pp. 113-120
-
-
Wei, M.1
Xu, J.2
Dignam, J.3
Nanda, R.4
Sveen, L.5
Fackenthal, J.6
Grushko, T.A.7
Olopade, O.I.8
-
7
-
-
0033281717
-
The pathology of familial breast cancer: How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology?
-
11250682 10.1186/bcr12 1:CAS:528:DC%2BD3cXlsFKgsbY%3D
-
D Bertwistle A Ashworth 1999 The pathology of familial breast cancer: How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology? Breast Cancer Res 1 1 41 47 11250682 10.1186/bcr12 1:CAS:528:DC%2BD3cXlsFKgsbY%3D
-
(1999)
Breast Cancer Res
, vol.1
, Issue.1
, pp. 41-47
-
-
Bertwistle, D.1
Ashworth, A.2
-
8
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
12787778 10.1016/S0955-0674(03)00042-5 1:CAS:528:DC%2BD3sXkt1KnsLo%3D
-
LM Starita JD Parvin 2003 The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair Curr Opin Cell Biol 15 3 345 350 12787778 10.1016/S0955-0674(03)00042-5 1:CAS:528:DC%2BD3sXkt1KnsLo%3D
-
(2003)
Curr Opin Cell Biol
, vol.15
, Issue.3
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
9
-
-
33645003172
-
BRCA1: Cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
-
16522651 10.1093/nar/gkl010 1:CAS:528:DC%2BD28XjtFSrs74%3D
-
CX Deng 2006 BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution Nucleic Acids Res 34 5 1416 1426 16522651 10.1093/nar/gkl010 1:CAS:528:DC%2BD28XjtFSrs74%3D
-
(2006)
Nucleic Acids Res
, vol.34
, Issue.5
, pp. 1416-1426
-
-
Deng, C.X.1
-
10
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
10.1038/nrm2831 1:CAS:528:DC%2BD1MXhsF2hs7fF
-
MS Huen SM Sy J Chen 2010 BRCA1 and its toolbox for the maintenance of genome integrity Natl Rev Mol Cell Biol 11 2 138 148 10.1038/nrm2831 1:CAS:528:DC%2BD1MXhsF2hs7fF
-
(2010)
Natl Rev Mol Cell Biol
, vol.11
, Issue.2
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
11
-
-
0141885140
-
Novel consensus DNA-binding sequence for BRCA1 protein complexes
-
14502648 10.1002/mc.10148 1:CAS:528:DC%2BD3sXotlWiur0%3D
-
PL Cable CA Wilson FJ Calzone FJ Rauscher 3rd R Scully DM Livingston L Li CB Blackwell PA Futreal CA Afshari 2003 Novel consensus DNA-binding sequence for BRCA1 protein complexes Mol Carcinog 38 2 85 96 14502648 10.1002/mc.10148 1:CAS:528:DC%2BD3sXotlWiur0%3D
-
(2003)
Mol Carcinog
, vol.38
, Issue.2
, pp. 85-96
-
-
Cable, P.L.1
Wilson, C.A.2
Calzone, F.J.3
Rauscher III, F.J.4
Scully, R.5
Livingston, D.M.6
Li, L.7
Blackwell, C.B.8
Futreal, P.A.9
Afshari, C.A.10
-
12
-
-
0029830051
-
Transcriptional activation by BRCA1
-
8751436 10.1038/382678a0 1:CAS:528:DyaK28Xlt1ylsbg%3D
-
MS Chapman IM Verma 1996 Transcriptional activation by BRCA1 Nature 382 6593 678 679 8751436 10.1038/382678a0 1:CAS:528:DyaK28Xlt1ylsbg%3D
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 678-679
-
-
Chapman, M.S.1
Verma, I.M.2
-
13
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
19763153 10.1038/nrg2634 1:CAS:528:DC%2BD1MXhtFCqurjE
-
CM Croce 2009 Causes and consequences of microRNA dysregulation in cancer Nat Rev Genet 10 10 704 714 19763153 10.1038/nrg2634 1:CAS:528: DC%2BD1MXhtFCqurjE
-
(2009)
Nat Rev Genet
, vol.10
, Issue.10
, pp. 704-714
-
-
Croce, C.M.1
-
14
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
15944708 10.1038/nature03702 1:CAS:528:DC%2BD2MXkvVGgsLc%3D
-
J Lu G Getz EA Miska E Alvarez-Saavedra J Lamb D Peck A Sweet-Cordero BL Ebert RH Mak AA Ferrando JR Downing T Jacks HR Horvitz TR Golub 2005 MicroRNA expression profiles classify human cancers Nature 435 7043 834 838 15944708 10.1038/nature03702 1:CAS:528:DC%2BD2MXkvVGgsLc%3D
-
(2005)
Nature
, vol.435
, Issue.7043
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
15
-
-
33747334621
-
Extensive post-transcriptional regulation of microRNAs and its implications for cancer
-
16882971 10.1101/gad.1444406 1:CAS:528:DC%2BD28XoslWqu70%3D
-
JM Thomson M Newman JS Parker EM Morin-Kensicki T Wright SM Hammond 2006 Extensive post-transcriptional regulation of microRNAs and its implications for cancer Genes Dev 20 16 2202 2207 16882971 10.1101/gad.1444406 1:CAS:528:DC%2BD28XoslWqu70%3D
-
(2006)
Genes Dev
, vol.20
, Issue.16
, pp. 2202-2207
-
-
Thomson, J.M.1
Newman, M.2
Parker, J.S.3
Morin-Kensicki, E.M.4
Wright, T.5
Hammond, S.M.6
-
16
-
-
78650686123
-
MicroRNA regulation of core apoptosis pathways in cancer
-
21145728 10.1016/j.ejca.2010.11.005 1:CAS:528:DC%2BC3MXptVOj
-
RT Lima S Busacca GM Almeida G Gaudino DA Fennell MH Vasconcelos 2011 MicroRNA regulation of core apoptosis pathways in cancer Eur J Cancer 47 2 163 174 21145728 10.1016/j.ejca.2010.11.005 1:CAS:528:DC%2BC3MXptVOj
-
(2011)
Eur J Cancer
, vol.47
, Issue.2
, pp. 163-174
-
-
Lima, R.T.1
Busacca, S.2
Almeida, G.M.3
Gaudino, G.4
Fennell, D.A.5
Vasconcelos, M.H.6
-
17
-
-
55149109188
-
Regulation of microRNA processing in development, differentiation and cancer
-
18752632 10.1111/j.1582-4934.2008.00483.x 1:CAS:528:DC%2BD1cXhsVOgu7zJ
-
TD Schmittgen 2008 Regulation of microRNA processing in development, differentiation and cancer J Cell Mol Med 12 5B 1811 1819 18752632 10.1111/j.1582-4934.2008.00483.x 1:CAS:528:DC%2BD1cXhsVOgu7zJ
-
(2008)
J Cell Mol Med
, vol.12
, Issue.5 B
, pp. 1811-1819
-
-
Schmittgen, T.D.1
-
18
-
-
37549024511
-
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
-
17922911 10.1186/gb-2007-8-10-r214
-
C Blenkiron LD Goldstein NP Thorne I Spiteri SF Chin MJ Dunning NL Barbosa-Morais AE Teschendorff AR Green IO Ellis S Tavare C Caldas EA Miska 2007 MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype Genome Biol 8 10 R214 17922911 10.1186/gb-2007-8-10-r214
-
(2007)
Genome Biol
, vol.8
, Issue.10
, pp. 214
-
-
Blenkiron, C.1
Goldstein, L.D.2
Thorne, N.P.3
Spiteri, I.4
Chin, S.F.5
Dunning, M.J.6
Barbosa-Morais, N.L.7
Teschendorff, A.E.8
Green, A.R.9
Ellis, I.O.10
Tavare, S.11
Caldas, C.12
Miska, E.A.13
-
19
-
-
76249103552
-
MRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer
-
19723326 10.1186/gb-2009-10-9-r90
-
C Cheng X Fu P Alves M Gerstein 2009 mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer Genome Biol 10 9 R90 19723326 10.1186/gb-2009-10-9-r90
-
(2009)
Genome Biol
, vol.10
, Issue.9
, pp. 90
-
-
Cheng, C.1
Fu, X.2
Alves, P.3
Gerstein, M.4
-
20
-
-
79952049614
-
MiRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
-
21364938 10.1371/journal.pone.0016915 1:CAS:528:DC%2BC3MXivVylsrk%3D
-
E Enerly I Steinfeld K Kleivi SK Leivonen MR Aure HG Russnes JA Ronneberg H Johnsen R Navon E Rodland R Makela B Naume M Perala O Kallioniemi VN Kristensen Z Yakhini AL Borresen-Dale 2011 miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors PLoS ONE 6 2 e16915 21364938 10.1371/journal.pone.0016915 1:CAS:528:DC%2BC3MXivVylsrk%3D
-
(2011)
PLoS ONE
, vol.6
, Issue.2
, pp. 16915
-
-
Enerly, E.1
Steinfeld, I.2
Kleivi, K.3
Leivonen, S.K.4
Aure, M.R.5
Russnes, H.G.6
Ronneberg, J.A.7
Johnsen, H.8
Navon, R.9
Rodland, E.10
Makela, R.11
Naume, B.12
Perala, M.13
Kallioniemi, O.14
Kristensen, V.N.15
Yakhini, Z.16
Borresen-Dale, A.L.17
-
21
-
-
18544368238
-
BRCA1 regulates the interferon gamma-mediated apoptotic response
-
12011077 10.1074/jbc.M201316200 1:CAS:528:DC%2BD38XlsFKrtL4%3D
-
HN Andrews PB Mullan S McWilliams S Sebelova JE Quinn PM Gilmore N McCabe A Pace B Koller PG Johnston DA Haber DP Harkin 2002 BRCA1 regulates the interferon gamma-mediated apoptotic response J Biol Chem 277 29 26225 26232 12011077 10.1074/jbc.M201316200 1:CAS:528:DC%2BD38XlsFKrtL4%3D
-
(2002)
J Biol Chem
, vol.277
, Issue.29
, pp. 26225-26232
-
-
Andrews, H.N.1
Mullan, P.B.2
McWilliams, S.3
Sebelova, S.4
Quinn, J.E.5
Gilmore, P.M.6
McCabe, N.7
Pace, A.8
Koller, B.9
Johnston, P.G.10
Haber, D.A.11
Harkin, D.P.12
-
22
-
-
33745713176
-
Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature
-
16843262 10.1016/j.ccr.2006.05.022 1:CAS:528:DC%2BD28XnsFOhsrY%3D
-
S Furuta JM Wang S Wei YM Jeng X Jiang B Gu PL Chen EY Lee WH Lee 2006 Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature Cancer Cell 10 1 13 24 16843262 10.1016/j.ccr.2006.05.022 1:CAS:528: DC%2BD28XnsFOhsrY%3D
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 13-24
-
-
Furuta, S.1
Wang, J.M.2
Wei, S.3
Jeng, Y.M.4
Jiang, X.5
Gu, B.6
Chen, P.L.7
Lee, E.Y.8
Lee, W.H.9
-
23
-
-
0033612303
-
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
-
10367887 10.1016/S0092-8674(00)80769-2 1:CAS:528:DyaK1MXjs1yqtb0%3D
-
DP Harkin JM Bean D Miklos YH Song VB Truong C Englert FC Christians LW Ellisen S Maheswaran JD Oliner DA Haber 1999 Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1 Cell 97 5 575 586 10367887 10.1016/S0092-8674(00)80769-2 1:CAS:528:DyaK1MXjs1yqtb0%3D
-
(1999)
Cell
, vol.97
, Issue.5
, pp. 575-586
-
-
Harkin, D.P.1
Bean, J.M.2
Miklos, D.3
Song, Y.H.4
Truong, V.B.5
Englert, C.6
Christians, F.C.7
Ellisen, L.W.8
Maheswaran, S.9
Oliner, J.D.10
Haber, D.A.11
-
24
-
-
0036724986
-
BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair
-
12195423 10.1038/ng953 1:CAS:528:DC%2BD38Xms1ajsLg%3D
-
AR Hartman JM Ford 2002 BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair Nat Genet 32 1 180 184 12195423 10.1038/ng953 1:CAS:528:DC%2BD38Xms1ajsLg%3D
-
(2002)
Nat Genet
, vol.32
, Issue.1
, pp. 180-184
-
-
Hartman, A.R.1
Ford, J.M.2
-
25
-
-
76249108620
-
BRCA1 represses amphiregulin gene expression
-
20103632 10.1158/0008-5472.CAN-09-2842 1:CAS:528:DC%2BC3cXht12qs78%3D
-
EP Lamber AA Horwitz JD Parvin 2010 BRCA1 represses amphiregulin gene expression Cancer Res 70 3 996 1005 20103632 10.1158/0008-5472.CAN-09-2842 1:CAS:528:DC%2BC3cXht12qs78%3D
-
(2010)
Cancer Res
, vol.70
, Issue.3
, pp. 996-1005
-
-
Lamber, E.P.1
Horwitz, A.A.2
Parvin, J.D.3
-
26
-
-
0034723347
-
BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
-
10644742 10.1074/jbc.275.4.2777 1:CAS:528:DC%2BD3cXpvFCmtA%3D%3D
-
TK MacLachlan K Somasundaram M Sgagias Y Shifman RJ Muschel KH Cowan WS El-Deiry 2000 BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression J Biol Chem 275 4 2777 2785 10644742 10.1074/jbc.275.4.2777 1:CAS:528:DC%2BD3cXpvFCmtA%3D%3D
-
(2000)
J Biol Chem
, vol.275
, Issue.4
, pp. 2777-2785
-
-
MacLachlan, T.K.1
Somasundaram, K.2
Sgagias, M.3
Shifman, Y.4
Muschel, R.J.5
Cowan, K.H.6
El-Deiry, W.S.7
-
27
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
12024039 10.1128/MCB.22.12.4280-4292.2002 1:CAS:528:DC%2BD38XktlSlsr4%3D
-
TK MacLachlan R Takimoto WS El-Deiry 2002 BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets Mol Cell Biol 22 12 4280 4292 12024039 10.1128/MCB.22.12.4280-4292.2002 1:CAS:528:DC%2BD38XktlSlsr4%3D
-
(2002)
Mol Cell Biol
, vol.22
, Issue.12
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
28
-
-
77954656203
-
Mantle cell lymphoma: Transcriptional regulation by microRNAs
-
20485376 10.1038/leu.2010.91 1:CAS:528:DC%2BC3cXovFKmsrc%3D
-
L Di Lisio G Gomez-Lopez M Sanchez-Beato C Gomez-Abad ME Rodriguez R Villuendas BI Ferreira A Carro D Rico M Mollejo MA Martinez J Menarguez A Diaz-Alderete J Gil JC Cigudosa DG Pisano MA Piris N Martinez 2010 Mantle cell lymphoma: transcriptional regulation by microRNAs Leukemia 24 7 1335 1342 20485376 10.1038/leu.2010.91 1:CAS:528:DC%2BC3cXovFKmsrc%3D
-
(2010)
Leukemia
, vol.24
, Issue.7
, pp. 1335-1342
-
-
Di Lisio, L.1
Gomez-Lopez, G.2
Sanchez-Beato, M.3
Gomez-Abad, C.4
Rodriguez, M.E.5
Villuendas, R.6
Ferreira, B.I.7
Carro, A.8
Rico, D.9
Mollejo, M.10
Martinez, M.A.11
Menarguez, J.12
Diaz-Alderete, A.13
Gil, J.14
Cigudosa, J.C.15
Pisano, D.G.16
Piris, M.A.17
Martinez, N.18
-
29
-
-
0032571569
-
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways
-
9559646 10.1016/S0014-5793(98)00226-9 1:CAS:528:DyaK1cXhvFGqsbc%3D
-
I Carpentier W Declercq NL Malinin D Wallach W Fiers R Beyaert 1998 TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways FEBS Lett 425 2 195 198 9559646 10.1016/S0014-5793(98)00226-9 1:CAS:528:DyaK1cXhvFGqsbc%3D
-
(1998)
FEBS Lett
, vol.425
, Issue.2
, pp. 195-198
-
-
Carpentier, I.1
Declercq, W.2
Malinin, N.L.3
Wallach, D.4
Fiers, W.5
Beyaert, R.6
-
30
-
-
34249854866
-
A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase
-
17420471 10.1073/pnas.0610481104 1:CAS:528:DC%2BD2sXkvFSqu7g%3D
-
AA Horwitz B Affar el GF Heine Y Shi JD Parvin 2007 A mechanism for transcriptional repression dependent on the BRCA1 E3 ubiquitin ligase Proc Natl Acad Sci USA 104 16 6614 6619 17420471 10.1073/pnas.0610481104 1:CAS:528:DC%2BD2sXkvFSqu7g%3D
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.16
, pp. 6614-6619
-
-
Horwitz, A.A.1
Affar El, B.2
Heine, G.F.3
Shi, Y.4
Parvin, J.D.5
-
31
-
-
33646829794
-
Direct stimulation of transcription initiation by BRCA1 requires both its amino and carboxyl termini
-
16473884 10.1074/jbc.C500475200 1:CAS:528:DC%2BD28XivVCgtLg%3D
-
AA Horwitz S Sankaran JD Parvin 2006 Direct stimulation of transcription initiation by BRCA1 requires both its amino and carboxyl termini J Biol Chem 281 13 8317 8320 16473884 10.1074/jbc.C500475200 1:CAS:528:DC%2BD28XivVCgtLg%3D
-
(2006)
J Biol Chem
, vol.281
, Issue.13
, pp. 8317-8320
-
-
Horwitz, A.A.1
Sankaran, S.2
Parvin, J.D.3
-
32
-
-
53349120042
-
A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
-
18660546 10.1093/carcin/bgn172 1:CAS:528:DC%2BD1cXht1SitLrN
-
J Shen CB Ambrosone RA DiCioccio K Odunsi SB Lele H Zhao 2008 A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis Carcinogenesis 29 10 1963 1966 18660546 10.1093/carcin/bgn172 1:CAS:528:DC%2BD1cXht1SitLrN
-
(2008)
Carcinogenesis
, vol.29
, Issue.10
, pp. 1963-1966
-
-
Shen, J.1
Ambrosone, C.B.2
Dicioccio, R.A.3
Odunsi, K.4
Lele, S.B.5
Zhao, H.6
-
33
-
-
74049088856
-
Lost in translation: An assessment and perspective for computational microRNA target identification
-
19789267 10.1093/bioinformatics/btp565 1:CAS:528:DC%2BD1MXhsVGlsb7M
-
P Alexiou M Maragkakis GL Papadopoulos M Reczko AG Hatzigeorgiou 2009 Lost in translation: an assessment and perspective for computational microRNA target identification Bioinformatics 25 23 3049 3055 19789267 10.1093/bioinformatics/btp565 1:CAS:528:DC%2BD1MXhsVGlsb7M
-
(2009)
Bioinformatics
, vol.25
, Issue.23
, pp. 3049-3055
-
-
Alexiou, P.1
Maragkakis, M.2
Papadopoulos, G.L.3
Reczko, M.4
Hatzigeorgiou, A.G.5
-
34
-
-
34249025114
-
Prediction of microRNA targets
-
17532529 10.1016/j.drudis.2007.04.002 1:CAS:528:DC%2BD2sXlvVart7o%3D
-
P Maziere AJ Enright 2007 Prediction of microRNA targets Drug Discov Today 12 11-12 452 458 17532529 10.1016/j.drudis.2007.04.002 1:CAS:528:DC%2BD2sXlvVart7o%3D
-
(2007)
Drug Discov Today
, vol.12
, Issue.1112
, pp. 452-458
-
-
Maziere, P.1
Enright, A.J.2
-
35
-
-
0034522714
-
Overexpression of mitogen-activated protein kinase superfamily proteins unrelated to Ras and AF-1 of estrogen receptor alpha mutation in advanced stage human breast cancer
-
11156322 10.1016/S0344-0338(00)80081-3 1:CAS:528:DC%2BD3MXps1Whtw%3D%3D
-
M Hori S Inagawa J Shimazaki M Itabashi 2000 Overexpression of mitogen-activated protein kinase superfamily proteins unrelated to Ras and AF-1 of estrogen receptor alpha mutation in advanced stage human breast cancer Pathol Res Pract 196 12 817 826 11156322 10.1016/S0344-0338(00)80081-3 1:CAS:528:DC%2BD3MXps1Whtw%3D%3D
-
(2000)
Pathol Res Pract
, vol.196
, Issue.12
, pp. 817-826
-
-
Hori, M.1
Inagawa, S.2
Shimazaki, J.3
Itabashi, M.4
-
36
-
-
77449145601
-
Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development
-
19818165 10.1186/bcr2361
-
J Whyte O Bergin A Bianchi S McNally F Martin 2009 Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development Breast Cancer Res 11 5 209 19818165 10.1186/bcr2361
-
(2009)
Breast Cancer Res
, vol.11
, Issue.5
, pp. 209
-
-
Whyte, J.1
Bergin, O.2
Bianchi, A.3
McNally, S.4
Martin, F.5
-
37
-
-
0029874138
-
The NF-kappa B and i kappa B proteins: New discoveries and insights
-
8717528 10.1146/annurev.immunol.14.1.649 1:CAS:528:DyaK28XitlCgtbc%3D
-
AS Baldwin Jr 1996 The NF-kappa B and I kappa B proteins: new discoveries and insights Annu Rev Immunol 14 649 683 8717528 10.1146/annurev.immunol.14.1. 649 1:CAS:528:DyaK28XitlCgtbc%3D
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin Jr., A.S.1
-
38
-
-
0029976817
-
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
-
8864118 10.1126/science.274.5288.782 1:CAS:528:DyaK28XmsFOhu70%3D
-
AA Beg D Baltimore 1996 An essential role for NF-kappaB in preventing TNF-alpha-induced cell death Science 274 5288 782 784 8864118 10.1126/science.274.5288.782 1:CAS:528:DyaK28XmsFOhu70%3D
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
39
-
-
0029992609
-
Suppression of TNF-alpha-induced apoptosis by NF-kappaB
-
8864120 10.1126/science.274.5288.787
-
DJ Van Antwerp SJ Martin T Kafri DR Green IM Verma 1996 Suppression of TNF-alpha-induced apoptosis by NF-kappaB Science 274 5288 787 789 8864120 10.1126/science.274.5288.787
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
40
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
8864119 10.1126/science.274.5288.784 1:CAS:528:DyaK28XmsFOhu7Y%3D
-
CY Wang MW Mayo AS Baldwin Jr 1996 TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB Science 274 5288 784 787 8864119 10.1126/science.274.5288.784 1:CAS:528:DyaK28XmsFOhu7Y%3D
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
41
-
-
68149164689
-
NFkappaB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation
-
19276662 10.4161/cbt.8.9.8105 1:CAS:528:DC%2BD1MXovFOns7Y%3D
-
R Madhusoodhanan M Natarajan J Veeraraghavan TS Herman N Aravindan 2009 NFkappaB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation Cancer Biol Ther 8 9 765 773 19276662 10.4161/cbt.8.9.8105 1:CAS:528:DC%2BD1MXovFOns7Y%3D
-
(2009)
Cancer Biol Ther
, vol.8
, Issue.9
, pp. 765-773
-
-
Madhusoodhanan, R.1
Natarajan, M.2
Veeraraghavan, J.3
Herman, T.S.4
Aravindan, N.5
-
42
-
-
14644422665
-
Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers
-
15743683 10.1016/j.biocel.2004.09.006 1:CAS:528:DC%2BD2MXhvVGjsr8%3D
-
Y Zhou S Eppenberger-Castori C Marx C Yau GK Scott U Eppenberger CC Benz 2005 Activation of nuclear factor-kappaB (NFkappaB) identifies a high-risk subset of hormone-dependent breast cancers Int J Biochem Cell Biol 37 5 1130 1144 15743683 10.1016/j.biocel.2004.09.006 1:CAS:528:DC%2BD2MXhvVGjsr8%3D
-
(2005)
Int J Biochem Cell Biol
, vol.37
, Issue.5
, pp. 1130-1144
-
-
Zhou, Y.1
Eppenberger-Castori, S.2
Marx, C.3
Yau, C.4
Scott, G.K.5
Eppenberger, U.6
Benz, C.C.7
-
43
-
-
51649112926
-
NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells
-
17965935 10.1007/s10549-007-9798-y 1:CAS:528:DC%2BD1cXhtV2js7bI
-
J Zhou H Zhang P Gu J Bai JB Margolick Y Zhang 2008 NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells Breast Cancer Res Treat 111 3 419 427 17965935 10.1007/s10549-007-9798-y 1:CAS:528: DC%2BD1cXhtV2js7bI
-
(2008)
Breast Cancer Res Treat
, vol.111
, Issue.3
, pp. 419-427
-
-
Zhou, J.1
Zhang, H.2
Gu, P.3
Bai, J.4
Margolick, J.B.5
Zhang, Y.6
-
44
-
-
0037962488
-
BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit
-
12700228 10.1074/jbc.M303076200 1:CAS:528:DC%2BD3sXltlKru74%3D
-
M Benezra N Chevallier DJ Morrison TK MacLachlan WS El-Deiry JD Licht 2003 BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit J Biol Chem 278 29 26333 26341 12700228 10.1074/jbc.M303076200 1:CAS:528:DC%2BD3sXltlKru74%3D
-
(2003)
J Biol Chem
, vol.278
, Issue.29
, pp. 26333-26341
-
-
Benezra, M.1
Chevallier, N.2
Morrison, D.J.3
MacLachlan, T.K.4
El-Deiry, W.S.5
Licht, J.D.6
-
45
-
-
52149102044
-
Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
-
18504431 10.1038/onc.2008.171 1:CAS:528:DC%2BD1cXhtFant7%2FE
-
D Bhaumik GK Scott S Schokrpur CK Patil J Campisi CC Benz 2008 Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells Oncogene 27 42 5643 5647 18504431 10.1038/onc.2008.171 1:CAS:528:DC%2BD1cXhtFant7%2FE
-
(2008)
Oncogene
, vol.27
, Issue.42
, pp. 5643-5647
-
-
Bhaumik, D.1
Scott, G.K.2
Schokrpur, S.3
Patil, C.K.4
Campisi, J.5
Benz, C.C.6
-
46
-
-
33747608638
-
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
16885212 10.1073/pnas.0605298103 1:CAS:528:DC%2BD28Xos1Kqt7g%3D
-
KD Taganov MP Boldin KJ Chang D Baltimore 2006 NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses Proc Natl Acad Sci USA 103 33 12481 12486 16885212 10.1073/pnas.0605298103 1:CAS:528:DC%2BD28Xos1Kqt7g%3D
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.33
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
Baltimore, D.4
-
47
-
-
70349944338
-
Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis
-
19826428 10.1038/sj.bjc.6605275 1:CAS:528:DC%2BD1MXht1GnurzN
-
R Fernandez-Ramires X Sole L De Cecco G Llort A Cazorla N Bonifaci MJ Garcia T Caldes I Blanco M Gariboldi MA Pierotti MA Pujana J Benitez A Osorio 2009 Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis Br J Cancer 101 8 1469 1480 19826428 10.1038/sj.bjc.6605275 1:CAS:528:DC%2BD1MXht1GnurzN
-
(2009)
Br J Cancer
, vol.101
, Issue.8
, pp. 1469-1480
-
-
Fernandez-Ramires, R.1
Sole, X.2
De Cecco, L.3
Llort, G.4
Cazorla, A.5
Bonifaci, N.6
Garcia, M.J.7
Caldes, T.8
Blanco, I.9
Gariboldi, M.10
Pierotti, M.A.11
Pujana, M.A.12
Benitez, J.13
Osorio, A.14
-
48
-
-
0031962348
-
4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB
-
9418902 1:CAS:528:DyaK1cXjtFSjug%3D%3D
-
RH Arch CB Thompson 1998 4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB Mol Cell Biol 18 1 558 565 9418902 1:CAS:528:DyaK1cXjtFSjug%3D%3D
-
(1998)
Mol Cell Biol
, vol.18
, Issue.1
, pp. 558-565
-
-
Arch, R.H.1
Thompson, C.B.2
-
49
-
-
0031029220
-
Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2
-
9032281 1:CAS:528:DyaK2sXhtlyltrc%3D
-
CS Duckett RW Gedrich MC Gilfillan CB Thompson 1997 Induction of nuclear factor kappaB by the CD30 receptor is mediated by TRAF1 and TRAF2 Mol Cell Biol 17 3 1535 1542 9032281 1:CAS:528:DyaK2sXhtlyltrc%3D
-
(1997)
Mol Cell Biol
, vol.17
, Issue.3
, pp. 1535-1542
-
-
Duckett, C.S.1
Gedrich, R.W.2
Gilfillan, M.C.3
Thompson, C.B.4
-
50
-
-
0030032106
-
TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
-
8565075 10.1016/S0092-8674(00)80984-8 1:CAS:528:DyaK28Xnt1egtA%3D%3D
-
H Hsu HB Shu MG Pan DV Goeddel 1996 TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways Cell 84 2 299 308 8565075 10.1016/S0092-8674(00)80984-8 1:CAS:528: DyaK28Xnt1egtA%3D%3D
-
(1996)
Cell
, vol.84
, Issue.2
, pp. 299-308
-
-
Hsu, H.1
Shu, H.B.2
Pan, M.G.3
Goeddel, D.V.4
-
51
-
-
0031048067
-
Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2
-
9118946 10.1093/emboj/16.5.1080 1:CAS:528:DyaK2sXitF2ls7g%3D
-
C Reinhard B Shamoon V Shyamala LT Williams 1997 Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2 EMBO J 16 5 1080 1092 9118946 10.1093/emboj/16.5.1080 1:CAS:528:DyaK2sXitF2ls7g%3D
-
(1997)
EMBO J
, vol.16
, Issue.5
, pp. 1080-1092
-
-
Reinhard, C.1
Shamoon, B.2
Shyamala, V.3
Williams, L.T.4
-
52
-
-
0028978626
-
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
-
7544915 10.1126/science.7544915 1:CAS:528:DyaK2MXnvFCkt74%3D
-
M Rothe V Sarma VM Dixit DV Goeddel 1995 TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 Science 269 5229 1424 1427 7544915 10.1126/science.7544915 1:CAS:528:DyaK2MXnvFCkt74%3D
-
(1995)
Science
, vol.269
, Issue.5229
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
53
-
-
0029786304
-
Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins
-
8702708 10.1074/jbc.271.33.19935 1:CAS:528:DyaK28XltVKrsLs%3D
-
M Takeuchi M Rothe DV Goeddel 1996 Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins J Biol Chem 271 33 19935 19942 8702708 10.1074/jbc.271.33. 19935 1:CAS:528:DyaK28XltVKrsLs%3D
-
(1996)
J Biol Chem
, vol.271
, Issue.33
, pp. 19935-19942
-
-
Takeuchi, M.1
Rothe, M.2
Goeddel, D.V.3
-
54
-
-
0030298294
-
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
-
8898208 10.1016/S0092-8674(00)81375-6 1:CAS:528:DyaK28XmvVOqtLo%3D
-
ZG Liu H Hsu DV Goeddel M Karin 1996 Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death Cell 87 3 565 576 8898208 10.1016/S0092-8674(00) 81375-6 1:CAS:528:DyaK28XmvVOqtLo%3D
-
(1996)
Cell
, vol.87
, Issue.3
, pp. 565-576
-
-
Liu, Z.G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
55
-
-
0031013545
-
Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
-
8985011 10.1126/science.275.5297.200 1:CAS:528:DyaK2sXksFyiug%3D%3D
-
G Natoli A Costanzo A Ianni DJ Templeton JR Woodgett C Balsano M Levrero 1997 Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway Science 275 5297 200 203 8985011 10.1126/science.275. 5297.200 1:CAS:528:DyaK2sXksFyiug%3D%3D
-
(1997)
Science
, vol.275
, Issue.5297
, pp. 200-203
-
-
Natoli, G.1
Costanzo, A.2
Ianni, A.3
Templeton, D.J.4
Woodgett, J.R.5
Balsano, C.6
Levrero, M.7
-
56
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
8599092 10.1126/science.271.5252.1128 1:CAS:528:DyaK28Xht1Gktr8%3D
-
Z Cao WJ Henzel X Gao 1996 IRAK: a kinase associated with the interleukin-1 receptor Science 271 5252 1128 1131 8599092 10.1126/science.271. 5252.1128 1:CAS:528:DyaK28Xht1Gktr8%3D
-
(1996)
Science
, vol.271
, Issue.5252
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
57
-
-
12644272789
-
Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
-
9275204 10.1073/pnas.94.18.9792 1:CAS:528:DyaK2sXlvVWms7k%3D
-
HY Song CH Regnier CJ Kirschning DV Goeddel M Rothe 1997 Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2 Proc Natl Acad Sci USA 94 18 9792 9796 9275204 10.1073/pnas.94.18.9792 1:CAS:528:DyaK2sXlvVWms7k%3D
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.18
, pp. 9792-9796
-
-
Song, H.Y.1
Regnier, C.H.2
Kirschning, C.J.3
Goeddel, D.V.4
Rothe, M.5
|