The miR-322-TRAF3 circuit mediates the pro-apoptotic effect of high glucose on neural stem cells

Toxicological Sciences

Volumn 144, Issue 1, 2015, Pages 186-196

  Gu, Hui ^a,b   Yu, Jingwen ^a   Dong, Daoying ^a   Zhou, Qun ^a   Wang, Jian Ying ^a   Yang, Peixin ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; High glucose; MicroRNA 322; Neural stem cells; Oxidative stress; TRAF3

Indexed keywords

CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; GLUCOSE; MESSENGER RNA; MICRORNA; MICRORNA 322; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; ANTIOXIDANT; CASP3 PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; MIRN322 MICRORNA, MOUSE; SUPEROXIDE DISMUTASE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING SITE; CELL LYSATE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; MATERNAL DIABETES MELLITUS; MOUSE; NEURAL STEM CELL; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BLOOD; C57BL MOUSE; CELL LINE; DRUG EFFECTS; ENZYME ACTIVATION; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PATHOLOGY; PREGNANCY; PREGNANCY DIABETES MELLITUS; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

3' UNTRANSLATED REGIONS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BINDING SITES; BLOOD GLUCOSE; CASPASE 3; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; NEURAL STEM CELLS; OXIDATIVE STRESS; PREGNANCY; PREGNANCY IN DIABETICS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TNF RECEPTOR-ASSOCIATED FACTOR 3; TRANSFECTION;

EID: 84924506715     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu271     Document Type: Article

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