Identification of a regulatory domain controlling the Nppa-Nppb gene cluster during heart development and stress

Development (Cambridge)

Volumn 143, Issue 12, 2016, Pages 2135-2146

  Sergeeva, Irina A ^a   Hooijkaas, Ingeborg B ^a   Ruijter, Jan M ^a   van der Made, Ingeborg ^a   de Groot, Nina E ^a   van de Werken, Harmen J G ^b   Creemers, Esther E ^a   Christoffels, Vincent M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b ERASMUS MC CANCER INSTITUTE   (Netherlands)

Author keywords

Atrial and brain natriuretic peptide; Chromosome conformation; Epigenetics; Heart development; Hypertrophy; Mouse

Indexed keywords

LUCIFERASE; TRANSCRIPTION FACTOR CTCF; ATRIAL NATRIURETIC FACTOR RECEPTOR; HISTONE; LYSINE; NATRIURETIC PEPTIDE RECEPTOR B; NATRIURETIC PEPTIDE TYPE C; NPPA PROTEIN, MOUSE; PROTEIN PRECURSOR; RNA POLYMERASE II;

ACETYLATION; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CHROMATIN; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENHANCER REGION; EPIGENETICS; GENE; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; HEART DEVELOPMENT; HEART VENTRICLE CONTRACTION; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; MALE; MOUSE; NONHUMAN; NPPA GENE; NPPB GENE; PRIORITY JOURNAL; PROMOTER REGION; STRESS; TRANSIENT TRANSFECTION; TRANSVERSE AORTIC CONSTRICTION; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC EPIGENESIS; GENETICS; HEART; METABOLISM; MULTIGENE FAMILY; PHYSIOLOGICAL STRESS;

ACETYLATION; ANIMALS; ENHANCER ELEMENTS, GENETIC; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC LOCI; HEART; HISTONES; LYSINE; MICE; MODELS, BIOLOGICAL; MULTIGENE FAMILY; NATRIURETIC PEPTIDE, C-TYPE; PROMOTER REGIONS, GENETIC; PROTEIN PRECURSORS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; RNA POLYMERASE II; STRESS, PHYSIOLOGICAL;

EID: 84974794775     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.132019     Document Type: Article

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