Ginseng inhibits cardiomyocyte hypertrophy and heart failure via nhe-1 inhibition and attenuation of calcineurin activation

Circulation: Heart Failure

Volumn 4, Issue 1, 2011, Pages 79-88

  Guo, Juan ^a,b   Gan, Xiaohong Tracey ^a   Haist, James V ^a   Rajapurohitam, Venkatesh ^a   Zeidan, Asad ^a   Said Faruq, Nazo ^a   Karmazyn, Morris ^a  

^a WESTERN UNIVERSITY   (Canada)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Calcineurin; Ginsenosides; Heart failure; NHE 1; Phenylephrine

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; CALCINEURIN; PHENYLEPHRINE; SODIUM CALCIUM EXCHANGE PROTEIN; TRANSCRIPTION FACTOR GATA 4; CALCIUM; GROWTH FACTOR ACTIVATABLE NA H EXCHANGER NHE 1; GROWTH FACTOR-ACTIVATABLE NA-H EXCHANGER NHE-1; PLANT EXTRACT; SODIUM; SODIUM PROTON EXCHANGE PROTEIN; TRANSCRIPTION FACTOR NFAT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; GENE EXPRESSION; GINSENG; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE CELL; HYPERTROPHIC CARDIOMYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HYPERTROPHY; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CALCINEURIN; CALCIUM; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GATA4 TRANSCRIPTION FACTOR; HEART FAILURE; HYPERTROPHY; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; PANAX; PHENYLEPHRINE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM; SODIUM-HYDROGEN ANTIPORTER;

EID: 79952256605     PISSN: 19413289     EISSN: 19413297     Source Type: Journal    
DOI: 10.1161/CIRCHEARTFAILURE.110.957969     Document Type: Article

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