Atrial natriuretic factor in the developing heart: A signpost for cardiac morphogenesis

Canadian Journal of Physiology and Pharmacology

Volumn 89, Issue 8, 2011, Pages 533-537

  Bruneau, Benoit G ^a,b,c  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atrial natriuretic factor; Congenital heart disease; Embryology; Gene expression; Heart; Patterning; Transcription factors

Indexed keywords

ATRIAL NATRIURETIC FACTOR; DNA; MYOCYTE ENHANCER FACTOR 2; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TBX5; TROPONIN I;

ARTICLE; CONGENITAL HEART MALFORMATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEART MUSCLE CELL; HUMAN; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE;

ANIMALS; ATRIAL NATRIURETIC FACTOR; HEART; HEART DEFECTS, CONGENITAL; HUMANS; MORPHOGENESIS;

EID: 79961198756     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/y11-051     Document Type: Article

References (27)

1. Al-Baradie, R., Yamada, K., St Hilaire, C., Chan, W.M., Andrews, C., McIntosh, N., et al. 2002. Duane radial ray syndrome (Okihiro syndrome) maps to 20q13 and results from mutations in SALL4, a new member of the SAL family. Am. J. Hum. Genet. 71(5): 1195-1199. doi:10.1086/343821. PMID:12395297.
2. Argentin, S., Ardati, A., Tremblay, S., Lihrmann, I., Robitaille, L., Drouin, J., and Nemer, M. 1994. Developmental stage-specific regulation of atrial natriuretic factor gene transcription in cardiac cells. Mol. Cell. Biol. 14(1): 777-790. PMID:8264645.
3. Bruneau, B.G. 2008. The developmental genetics of congenital heart disease. Nature, 451(7181): 943-948. doi:10.1038/nature06801. PMID:18288184.
4. Bruneau, B.G., Nemer, G., Schmitt, J.P., Charron, F., Robitaille, L., Caron, S., et al. 2001. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogen-esis and disease. Cell, 106(6): 709-721. doi:10.1016/S0092-8674 (01)00493-7. PMID:11572777.
5. Christoffels, V.M., Habets, P.E., Franco, D., Campione, M., de Jong, F., Lamers, W.H., et al. 2000. Chamber formation and morphogenesis in the developing mammalian heart. Dev. Biol. 223(2): 266-278. doi:10.1006/dbio.2000.9753. PMID:10882515.
6. Durocher, D., and Nemer, M. 1998. Combinatorial interactions regulating cardiac transcription. Dev. Genet. 22(3): 250-262. doi:10.1002/(SICI)1520-6408(1998)22:3<250::AID-DVG7>3.0. CO;2-5. PMID:9621432.
7. Durocher, D., Chen, C.Y., Ardati, A., Schwartz, R.J., and Nemer, M. 1996. The atrial natriuretic factor promoter is a downstream target for Nkx- 2.5 in the myocardium. Mol. Cell. Biol. 16(9): 4648-4655. PMID:8756621.
8. Durocher, D., Charron, F., Warren, R., Schwartz, R.J., and Nemer, M. 1997. The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors. EMBO J. 16(18): 5687-5696. doi:10.1093/ emboj/16.18.5687. PMID:9312027.
9. Habets, P.E., Moorman, A.F., Clout, D.E., van Roon, M.A., Lingbeek, M., van Lohuizen, M., et al. 2002. Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev. 16(10): 1234-1246. doi:10.1101/gad.222902. PMID:12023302.
10. Habets, P.E., Moorman, A.F., and Christoffels, V.M. 2003. Regulatory modules in the developing heart. Cardiovasc. Res. 58(2): 246-263. doi:10.1016/S0008-6363(02)00784-8. PMID:12757861.
11. Hiroi, Y., Kudoh, S., Monzen, K., Ikeda, Y., Yazaki, Y., Nagai, R., and Komuro, I. 2001. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat. Genet. 28(3): 276-280. doi:10.1038/90123. PMID:11431700.
12. Horsthuis, T., Houweling, A.C., Habets, P.E., de Lange, F.J., el Azzouzi, H., Clout, D.E., et al. 2008. Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ. Res. 102(7): 849-859. doi:10.1161/CIRCRESAHA.107.170571. PMID: 18276916.
13. Houweling, A.C., Somi, S., Massink, M.P., Groenen, M.A., Moorman, A.F., and Christoffels, V.M. 2005a. Comparative analysis of the natriuretic peptide precursor gene cluster in vertebrates reveals loss of ANF and retention of CNP-3 in chicken. Dev. Dyn. 233(3): 1076-1082. doi:10.1002/dvdy.20423. PMID:15895405.
14. Houweling, A.C., van Borren, M.M., Moorman, A.F., and Chris-toffels, V.M. 2005b. Expression and regulation of the atrial natriuretic factor encoding gene Nppa during development and disease. Cardiovasc. Res. 67(4): 583-593. doi:10.1016/j.cardiores. 2005.06.013. PMID:16002056.
15. Kohlhase, J., Heinrich, M., Schubert, L., Liebers, M., Kispert, A., Laccone, F., et al. 2002. Okihiro syndrome is caused by SALL4 mutations. Hum. Mol. Genet. 11(23): 2979-2987. doi:10.1093/ hmg/11.23.2979. PMID:12393809.
16. Kohlhase, J., Schubert, L., Liebers, M., Rauch, A., Becker, K., Mohammed, S.N., et al. 2003. Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy. J. Med. Genet. 40(7): 473-478. doi:10.1136/jmg.40.7.473. PMID:12843316.
17. Koshiba-Takeuchi, K., Takeuchi, J.K., Arruda, E.P., Kathiriya, I.S., Mo, R., Hui, C.C., et al. 2006. Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart. Nat. Genet. 38(2): 175-183. doi:10.1038/ng1707. PMID: 16380715.
18. Koshiba-Takeuchi, K., Mori, A.D., Kaynak, B., Cebra-Thomas, J., Sukonnik, T., Georges, R.O., et al. 2009. Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature, 461(7260): 95-98. doi:10.1038/nature08324. PMID:19727199.
19. Lickert, H., Takeuchi, J.K., von Both, I., Walls, J.R., McAuliffe, F., Adamson, S.L., et al. 2004. Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature, 432(7013): 107-112. doi:10.1038/nature03071. PMID: 15525990.
20. Lin, Q., Schwarz, J., Bucana, C., and Olson, E.N. 1997. Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science, 276(5317): 1404-1407. doi:10.1126/ science.276.5317.1404. PMID:9162005.
21. Mori, A.D., and Bruneau, B.G. 2004. TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed. Curr. Opin. Cardiol. 19(3): 211-215. doi:10.1097/00001573-200405000-00004. PMID:15096952.
22. Morin, S., Charron, F., Robitaille, L., and Nemer, M. 2000. GATA-dependent recruitment of MEF2 proteins to target promoters. EMBO J. 19(9): 2046-2055. doi:10.1093/emboj/19.9.2046. PMID:10790371.
23. Srivastava, D. 2006. Making or breaking the heart: from lineage determination to morphogenesis. Cell, 126(6): 1037-1048. doi:10. 1016/j.cell.2006.09.003. PMID:16990131.
24. Takeuchi, J.K., and Bruneau, B.G. 2009. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature, 459(7247): 708-711. doi:10.1038/nature08039. PMID:19396158.
25. Takeuchi, J.K., Lou, X., Alexander, J.M., Sugizaki, H., Delgado-Olguin, P., Holloway, A.K., et al. 2011. Chromatin remodeling complex dosage modulates transcription factor function in heart development. Nat. Commun. 2: 187. doi:10.1038/ncomms1187. PMID:21304516.
26. Tanaka, M., Chen, Z., Bartunkova, M., Yamasaki, N., and Izumo, S. 1999. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development, 126(6): 1269-1280. PMID:10021345.
27. Zeller, R., Bloch, K.D., Williams, B.S., Arceci, R.J., and Seidman, C.E. 1987. Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis. Genes Dev. 1(7): 693-698. doi:10.1101/gad.1.7.693. PMID:2962900.