GCN2 contributes to mTORC1 inhibition by leucine deprivation through an ATF4 independent mechanism

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Averous, Julien ^a,b   Lambert Langlais, Sarah ^a,b   Mesclon, Florent ^a,b   Carraro, Valérie ^a,b   Parry, Laurent ^a,b   Jousse, Céline ^a,b   Bruhat, Alain ^a,b   Maurin, Anne Catherine ^a,b   Pierre, Philippe ^c,d,e,f   Proud, Christopher G ^g,h   Fafournoux, Pierre ^a,b  

^a INRA and University of Auvergne   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d INSERM   (France)

^e CNRS   (France)

^f UNIVERSITY OF AVEIRO   (Portugal)

^g SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE   (Australia)

^h UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ARGININE; EIF2AK4 PROTEIN, MOUSE; INITIATION FACTOR 2; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DEFICIENCY; FIBROBLAST; MAMMALIAN EMBRYO; METABOLISM; MOUSE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; ARGININE; EMBRYO, MAMMALIAN; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; LEUCINE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MICE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84974691273     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep27698     Document Type: Article

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