Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

Nature

Volumn 534, Issue 7605, 2016, Pages 119-123

  Tao, Ge ^a   Kahr, Peter C ^a   Morikawa, Yuka ^b   Zhang, Min ^a   Rahmani, Mahdis ^b   Heallen, Todd R ^b   Li, Lele ^a   Sun, Zhao ^c   Olson, Eric N ^d   Amendt, Brad A ^c   Martin, James F ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS HEART INSTITUTE   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR PITX2; ANTIOXIDANT; HIPPO PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; NFE2L2 PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SCAVENGER; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR; YAP PROTEIN, MOUSE;

ANTIOXIDANT; CARDIOLOGY; CARDIOVASCULAR DISEASE; EXPERIMENTAL STUDY; GENE EXPRESSION; GENETIC ANALYSIS; INJURY; MAMMAL; PROTEIN; REGENERATION; RODENT; SCAVENGER;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; GENE TARGETING; HEART INFARCTION; HEART INJURY; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; TISSUE INJURY; ANIMAL; CARDIAC MUSCLE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; ELECTRON TRANSPORT; GENETICS; HEART VENTRICLE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REGENERATION; WOUND HEALING;

MAMMALIA; VERTEBRATA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT; FEMALE; FREE RADICAL SCAVENGERS; HEART INJURIES; HEART VENTRICLES; HOMEODOMAIN PROTEINS; MALE; MICE; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; NF-E2-RELATED FACTOR 2; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; REGENERATION; TRANSCRIPTION FACTORS; WOUND HEALING;

EID: 84973630830     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17959     Document Type: Article

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