By suppressing the expression of anterior pharynx-defective-1α and -1β and inhibiting the aggregation of β-amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice

FASEB Journal

Volumn 29, Issue 12, 2015, Pages 5044-5058

  Yu, Xin ^a   Guan, Pei Pei ^a   Guo, Jing Wen ^a   Wang, Yue ^a   Cao, Long Long ^a   Xu, Guo Biao ^a   Konstantopoulos, Konstantinos ^b,c,d   Wang, Zhan You ^a   Wang, Pu ^a  

^a NORTHEASTERN UNIVERSITY   (China)

^b Johns Hopkins University   (United States)

^c Johns Hopkins University   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Cerebrospinal fluid; ERK1 2; Magnesium L threonate; PPAR

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1ALPHA PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1BETA PROTEIN; MAGNESIUM DERIVATIVE; MAGNESIUM LEVO THREONATE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOMER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PRESENILIN 1; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; APH1A PROTEIN, MOUSE; APH1B PROTEIN, MOUSE; MAGNESIUM; PRESENILIN 1, MOUSE; PROTEINASE;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DENTATE GYRUS; DOWN REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR PATHOLOGY; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; COGNITION DISORDERS; GENETICS; MAZE TEST; METABOLISM; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE, TUMOR; COGNITION DISORDERS; ENDOPEPTIDASES; HUMANS; MAGNESIUM; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; PRESENILIN-1;

EID: 84973413793     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-275578     Document Type: Article

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