메뉴 건너뛰기




Volumn 17, Issue 5, 2016, Pages 265-275

Gene-disease association with human IFNL locus polymorphisms extends beyond hepatitis C virus infections

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; IL28B PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE;

EID: 84973376124     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2016.24     Document Type: Review
Times cited : (20)

References (109)
  • 1
    • 0037243222 scopus 로고    scopus 로고
    • IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
    • Kotenko SV, Gallagher G, Baurin VV, Lewis-Antes A, Shen M, Shah NK et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat Immunol 2002; 4: 69-77.
    • (2002) Nat Immunol , vol.4 , pp. 69-77
    • Kotenko, S.V.1    Gallagher, G.2    Baurin, V.V.3    Lewis-Antes, A.4    Shen, M.5    Shah, N.K.6
  • 3
    • 77955860021 scopus 로고    scopus 로고
    • IL-28A, IL-28B, and IL-29: Promising cytokines with type I interferon-like properties
    • Witte K, Witte E, Sabat R, Wolk K. IL-28A, IL-28B, and IL-29: promising cytokines with type I interferon-like properties. Cytokine Growth Factor Rev 2010; 21: 237-251.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 237-251
    • Witte, K.1    Witte, E.2    Sabat, R.3    Wolk, K.4
  • 4
    • 1642370060 scopus 로고    scopus 로고
    • Viral infection and Toll like receptor agonists induce a differential expression of type I andλ interferons in human plasmacytoid and monocyte-derived dendritic cells
    • Coccia EM, Severa M, Giacomini E, E, Monneron D, Remoli ME, Julkunen I et al. Viral infection and Toll like receptor agonists induce a differential expression of type I andλ interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur J Immunol 2004; 34: 796-805.
    • (2004) Eur J Immunol , vol.34 , pp. 796-805
    • Coccia, E.M.1    Severa, M.2    Giacomini, E.E.3    Monneron, D.4    Remoli, M.E.5    Julkunen, I.6
  • 5
    • 42949160129 scopus 로고    scopus 로고
    • IFN-lambda (IFN-λ) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo
    • Sommereyns C, Paul S, Staeheli P, Michiels T. IFN-lambda (IFN-λ) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo. PLoS Pathog 2008; 4: e1000017.
    • (2008) PLoS Pathog , vol.4 , pp. e1000017
    • Sommereyns, C.1    Paul, S.2    Staeheli, P.3    Michiels, T.4
  • 7
    • 42149152139 scopus 로고    scopus 로고
    • An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity
    • Ank N, Iversen MB, Bartholdy C, Staeheli P, Hartmann R, Jensen UB et al. An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity. J Immunol 2008; 180: 2474-2485.
    • (2008) J Immunol , vol.180 , pp. 2474-2485
    • Ank, N.1    Iversen, M.B.2    Bartholdy, C.3    Staeheli, P.4    Hartmann, R.5    Jensen, U.B.6
  • 8
    • 84929493527 scopus 로고    scopus 로고
    • Leukocytederived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections
    • Mahlakoiv T, Hernandez P, Gronke K, Diefenbach A, Staeheli P. Leukocytederived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections. PLoS Pathog 2015; 11: e1004782.
    • (2015) PLoS Pathog , vol.11 , pp. e1004782
    • Mahlakoiv, T.1    Hernandez, P.2    Gronke, K.3    Diefenbach, A.4    Staeheli, P.5
  • 9
    • 84922480732 scopus 로고    scopus 로고
    • Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity
    • Nice TJ, Baldridge MT, McCune BT, Norman JM, Lazear HM, Artyomov M et al. Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity. Science 2015; 347: 269-273.
    • (2015) Science , vol.347 , pp. 269-273
    • Nice, T.J.1    Baldridge, M.T.2    McCune, B.T.3    Norman, J.M.4    Lazear, H.M.5    Artyomov, M.6
  • 10
    • 84937779845 scopus 로고    scopus 로고
    • Guarding the frontiers: The biology of type III interferons
    • Wack A, Terczyńska-Dyla E, Hartmann R. Guarding the frontiers: the biology of type III interferons. Nat Immunol 2015; 16: 802-809.
    • (2015) Nat Immunol , vol.16 , pp. 802-809
    • Wack, A.1    Terczyńska-Dyla, E.2    Hartmann, R.3
  • 11
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461: 399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3    Simon, J.S.4    Shianna, K.V.5    Urban, T.J.6
  • 12
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G, Berg T, Weltman M, Abate ML et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet 2009; 41: 1100-1104.
    • (2009) Nat Genet , vol.41 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3    Berg, T.4    Weltman, M.5    Abate, M.L.6
  • 13
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009; 41: 1105-1109.
    • (2009) Nat Genet , vol.41 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3    Kurosaki, M.4    Matsuura, K.5    Sakamoto, N.6
  • 14
    • 84873083416 scopus 로고    scopus 로고
    • Avariant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
    • Prokunina-Olsson L, Muchmore B, Tang W, Pfeiffer RM, Park H, Dickensheets H et al. Avariant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat Genet 2013; 45: 164-171.
    • (2013) Nat Genet , vol.45 , pp. 164-171
    • Prokunina-Olsson, L.1    Muchmore, B.2    Tang, W.3    Pfeiffer, R.M.4    Park, H.5    Dickensheets, H.6
  • 15
    • 84903767054 scopus 로고    scopus 로고
    • Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions
    • Chinnaswamy S. Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions. J Interferon Cytokine Res 2014; 34: 479-497.
    • (2014) J Interferon Cytokine Res , vol.34 , pp. 479-497
    • Chinnaswamy, S.1
  • 17
    • 84908335988 scopus 로고    scopus 로고
    • Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)
    • Key FM, Peter B, Dennis MY, Huerta-Sánchez E, Tang W, Prokunina-Olsson L et al. Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4). PLoS Genet 2014; 10: e1004681.
    • (2014) PLoS Genet , vol.10 , pp. e1004681
    • Key, F.M.1    Peter, B.2    Dennis, M.Y.3    Huerta-Sánchez, E.4    Tang, W.5    Prokunina-Olsson, L.6
  • 18
    • 0346157290 scopus 로고    scopus 로고
    • Innate immunity: An overview
    • Beutler B. Innate immunity: an overview. Mol Immunol 2004; 40: 845-859.
    • (2004) Mol Immunol , vol.40 , pp. 845-859
    • Beutler, B.1
  • 19
    • 66449088641 scopus 로고    scopus 로고
    • Pathogen recognition and inflammatory signaling in innate immune defenses
    • Mogensen TH. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 2009; 22: 240-273.
    • (2009) Clin Microbiol Rev , vol.22 , pp. 240-273
    • Mogensen, T.H.1
  • 20
    • 58049202272 scopus 로고    scopus 로고
    • Innate immunity to virus infection
    • Takeuchi O, Akira S. Innate immunity to virus infection. Immunol Rev 2009; 227: 75-86.
    • (2009) Immunol Rev , vol.227 , pp. 75-86
    • Takeuchi, O.1    Akira, S.2
  • 21
    • 84896851032 scopus 로고    scopus 로고
    • Intestinal epithelial cells: Regulators of barrier function and immune homeostasis
    • Peterson LW, Artis D. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat Rev Immunol 2014; 14: 141-153.
    • (2014) Nat Rev Immunol , vol.14 , pp. 141-153
    • Peterson, L.W.1    Artis, D.2
  • 22
    • 84936892270 scopus 로고    scopus 로고
    • Innate lymphoid cells in the initiation, regulation and resolution of inflammation
    • Sonnenberg GF, Artis D. Innate lymphoid cells in the initiation, regulation and resolution of inflammation. Nat Med 2015; 21: 698-708.
    • (2015) Nat Med , vol.21 , pp. 698-708
    • Sonnenberg, G.F.1    Artis, D.2
  • 23
    • 84922607138 scopus 로고    scopus 로고
    • The biology of innate lymphoid cells
    • Artis D, Spits H. The biology of innate lymphoid cells. Nature 2015; 517: 293-301.
    • (2015) Nature , vol.517 , pp. 293-301
    • Artis, D.1    Spits, H.2
  • 24
    • 84924548071 scopus 로고    scopus 로고
    • The 3 major types of innate and adaptive cell-mediated effector immunity
    • Annunziato F, Romagnani C, Romagnani S. The 3 major types of innate and adaptive cell-mediated effector immunity. J Allergy Clin Immunol 2015; 135: 626-635.
    • (2015) J Allergy Clin Immunol , vol.135 , pp. 626-635
    • Annunziato, F.1    Romagnani, C.2    Romagnani, S.3
  • 26
    • 84905098795 scopus 로고    scopus 로고
    • Human innate lymphoid cells
    • Hazenberg MD, Spits H. Human innate lymphoid cells. Blood 2014; 124: 700-709.
    • (2014) Blood , vol.124 , pp. 700-709
    • Hazenberg, M.D.1    Spits, H.2
  • 27
    • 84896804302 scopus 로고    scopus 로고
    • Regulation of the adaptive immune system by innate lymphoid cells
    • Hepworth MR, Sonnenberg GF. Regulation of the adaptive immune system by innate lymphoid cells. Curr Opin Immunol 2014; 27: 75-82.
    • (2014) Curr Opin Immunol , vol.27 , pp. 75-82
    • Hepworth, M.R.1    Sonnenberg, G.F.2
  • 28
    • 84937722616 scopus 로고    scopus 로고
    • Interferon-λ: Immune functions at barrier surfaces and beyond
    • Lazear HM, Nice TJ, Diamond MS. Interferon-λ: Immune functions at barrier surfaces and beyond. Immunity 2015; 43: 15-28.
    • (2015) Immunity , vol.43 , pp. 15-28
    • Lazear, H.M.1    Nice, T.J.2    Diamond, M.S.3
  • 29
    • 84867636023 scopus 로고    scopus 로고
    • Innate lymphoid cells: Balancing immunity, inflammation and tissue repair in the intestine
    • Wojno EDT, Artis D. Innate lymphoid cells: balancing immunity, inflammation and tissue repair in the intestine. Cell Host Microbe 2012; 12: 445-457.
    • (2012) Cell Host Microbe , vol.12 , pp. 445-457
    • Wojno, E.D.T.1    Artis, D.2
  • 30
    • 84888876575 scopus 로고    scopus 로고
    • Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses
    • Hamming OJ, Terczyńska-Dyla E, Vieyres G, Dijkman R, Jørgensen SE, Akhtar H. Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses. EMBO J 2013; 32: 3055-3065.
    • (2013) EMBO J , vol.32 , pp. 3055-3065
    • Hamming, O.J.1    Terczyńska-Dyla, E.2    Vieyres, G.3    Dijkman, R.4    Jørgensen, S.E.5    Akhtar, H.6
  • 31
    • 84888241256 scopus 로고    scopus 로고
    • Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia
    • Crotta S, Davidson S, Mahlakoiv T, Desmet CJ, Buckwalter MR, Albert ML et al. Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia. PLoS Pathog 2013; 9: e1003773.
    • (2013) PLoS Pathog , vol.9 , pp. e1003773
    • Crotta, S.1    Davidson, S.2    Mahlakoiv, T.3    Desmet, C.J.4    Buckwalter, M.R.5    Albert, M.L.6
  • 32
    • 13544263585 scopus 로고    scopus 로고
    • IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28 and IL-29
    • Siren J, Pirhonen J, Jullkunen I, Matikainen S. IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28 and IL-29. J Immunol 2005; 174: 1932-1937.
    • (2005) J Immunol , vol.174 , pp. 1932-1937
    • Siren, J.1    Pirhonen, J.2    Jullkunen, I.3    Matikainen, S.4
  • 33
    • 84866163478 scopus 로고    scopus 로고
    • Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells
    • Yin Z, Dai J, Deng J, Sheikh F, Natalia M, Shih T et al. Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells. J Immunol 2012; 189: 2735-2745.
    • (2012) J Immunol , vol.189 , pp. 2735-2745
    • Yin, Z.1    Dai, J.2    Deng, J.3    Sheikh, F.4    Natalia, M.5    Shih, T.6
  • 34
    • 84866428295 scopus 로고    scopus 로고
    • Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligandand cell-dependent
    • Hillyer P, Mane VP, Schramm LM, Puig M, Verthelyi D, Chen A et al. Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligandand cell-dependent. Immunol Cell Biol 2012; 90: 774-783.
    • (2012) Immunol Cell Biol , vol.90 , pp. 774-783
    • Hillyer, P.1    Mane, V.P.2    Schramm, L.M.3    Puig, M.4    Verthelyi, D.5    Chen, A.6
  • 35
    • 73849130903 scopus 로고    scopus 로고
    • Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: Implications for therapeutic applications of these cytokines
    • Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W et al. Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines. Genes Immun 2009; 10: 702-714.
    • (2009) Genes Immun , vol.10 , pp. 702-714
    • Witte, K.1    Gruetz, G.2    Volk, H.D.3    Looman, A.C.4    Asadullah, K.5    Sterry, W.6
  • 36
    • 84941022104 scopus 로고    scopus 로고
    • Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells
    • Lauber C, Vieyres G, Terczyńska-Dyla E, Anggakusuma, Dijkman R, Gad HH et al. Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes Immun 2015; 16: 414-421.
    • (2015) Genes Immun , vol.16 , pp. 414-421
    • Lauber, C.1    Vieyres, G.2    Terczyńska-Dyla, E.3    Anggakusuma4    Dijkman, R.5    Gad, H.H.6
  • 37
    • 84903779440 scopus 로고    scopus 로고
    • The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections
    • Egli A, Santer DM, ÓShea D, Tyrell DL, Houghton M. The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Emerg Microbes Infect 2014; 3: e51.
    • (2014) Emerg Microbes Infect , vol.3 , pp. e51
    • Egli, A.1    Santer, D.M.2    ÓShea, D.3    Tyrell, D.L.4    Houghton, M.5
  • 38
  • 39
    • 79957896032 scopus 로고    scopus 로고
    • IL-28 A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease
    • Koltsida O, Hausding M, Stavropoulos A, Koch S, Tzelepis G, Ubel C et al. IL-28 A (IFN-λ2) modulates lung DC function to promote Th1 immune skewing and suppress allergic airway disease. EMBO Mol Med 2011; 3: 348-361.
    • (2011) EMBO Mol Med , vol.3 , pp. 348-361
    • Koltsida, O.1    Hausding, M.2    Stavropoulos, A.3    Koch, S.4    Tzelepis, G.5    Ubel, C.6
  • 40
    • 84931569282 scopus 로고    scopus 로고
    • Interferon-l and interleukin 22act synergistically for the induction of interferonstimulated genes and control of rotavirus infection
    • Hernandez PP, Mahlakoiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F et al. Interferon-l and interleukin 22act synergistically for the induction of interferonstimulated genes and control of rotavirus infection. Nat Immunol 2015; 16: 698-707.
    • (2015) Nat Immunol , vol.16 , pp. 698-707
    • Hernandez, P.P.1    Mahlakoiv, T.2    Yang, I.3    Schwierzeck, V.4    Nguyen, N.5    Guendel, F.6
  • 41
    • 84920910019 scopus 로고    scopus 로고
    • Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden
    • Lu YF, Goldstein DB, Urban TJ, Bradrick SS. Interferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burden. Virology 2015; 476: 334-340.
    • (2015) Virology , vol.476 , pp. 334-340
    • Lu, Y.F.1    Goldstein, D.B.2    Urban, T.J.3    Bradrick, S.S.4
  • 42
    • 84902687808 scopus 로고    scopus 로고
    • Interferon lambda-2 levels in sputum of patients with pulmonary Mycobacterium tuberculosis infection
    • Travar M, Vucic M, Petkovic M. Interferon lambda-2 levels in sputum of patients with pulmonary Mycobacterium tuberculosis infection. Scand J Immunol 2014; 80: 43-49.
    • (2014) Scand J Immunol , vol.80 , pp. 43-49
    • Travar, M.1    Vucic, M.2    Petkovic, M.3
  • 43
    • 84902261904 scopus 로고    scopus 로고
    • Interferon lambda 1 expression in cervical cells differs between low-risk and high-risk human papillomavirus-positive women
    • Cannella F, Scagnolari C, Selvaggi C, Stentella P, Recine N, Antonelli G et al. Interferon lambda 1 expression in cervical cells differs between low-risk and high-risk human papillomavirus-positive women. Med Microbiol Immunol 2014; 203: 177-184.
    • (2014) Med Microbiol Immunol , vol.203 , pp. 177-184
    • Cannella, F.1    Scagnolari, C.2    Selvaggi, C.3    Stentella, P.4    Recine, N.5    Antonelli, G.6
  • 44
    • 84959511733 scopus 로고    scopus 로고
    • Influenza virus activation of the interferon system
    • Killip MJ, Fodor E, Randall RE. Influenza virus activation of the interferon system. Virus Res 2015; 209: 11-22.
    • (2015) Virus Res , vol.209 , pp. 11-22
    • Killip, M.J.1    Fodor, E.2    Randall, R.E.3
  • 46
    • 84906938384 scopus 로고    scopus 로고
    • Interferon-λ in the context of viral infections: Production, response and therapeutic implications
    • Hermant P, Michiels T. Interferon-λ in the context of viral infections: production, response and therapeutic implications. J Innate Immun 2014; 6: 563-574.
    • (2014) J Innate Immun , vol.6 , pp. 563-574
    • Hermant, P.1    Michiels, T.2
  • 47
    • 84907424313 scopus 로고    scopus 로고
    • Immunomodulatory function of interleukin 28B during primary infection with cytomegalovirus
    • Egli A, Levin A, Santer DM, Joyce M, ÓShea D, Thomas BS et al. Immunomodulatory function of interleukin 28B during primary infection with cytomegalovirus. J Infect Dis 2014; 210: 717-727.
    • (2014) J Infect Dis , vol.210 , pp. 717-727
    • Egli, A.1    Levin, A.2    Santer, D.M.3    Joyce, M.4    ÓShea, D.5    Thomas, B.S.6
  • 48
    • 84928008269 scopus 로고    scopus 로고
    • Association between individual and combined SNPs in genes related to innate immunity and incidence of CMV infection in seropositive kidney transplant patients
    • Fernández-Ruiz M, Corrales I, Arias M, Campistol JM, Giménez E, Crespo J et al. Association between individual and combined SNPs in genes related to innate immunity and incidence of CMV infection in seropositive kidney transplant patients. Am J Transplant 2015; 15: 1323-1335.
    • (2015) Am J Transplant , vol.15 , pp. 1323-1335
    • Fernández-Ruiz, M.1    Corrales, I.2    Arias, M.3    Campistol, J.M.4    Giménez, E.5    Crespo, J.6
  • 49
    • 84895922314 scopus 로고    scopus 로고
    • Effect of the IL28B Rs12979860 C/T polymorphism on the incidence and features of active cytomegalovirus infection in allogeneic stem cell transplant patients
    • Bravo D, Solano C, Giménez E, Remigia MJ, Corrales I, Amat P et al. Effect of the IL28B Rs12979860 C/T polymorphism on the incidence and features of active cytomegalovirus infection in allogeneic stem cell transplant patients. J Med Virol 2014; 86: 838-844.
    • (2014) J Med Virol , vol.86 , pp. 838-844
    • Bravo, D.1    Solano, C.2    Giménez, E.3    Remigia, M.J.4    Corrales, I.5    Amat, P.6
  • 50
    • 84906557493 scopus 로고    scopus 로고
    • The IFNL3/4 Δg variant increases susceptibility to cytomegalovirus retinitis among HIV-infected patients
    • Bibert S, Wojtowicz A, Taffé P, Manuel O, Bernasconi E, Furrer H et al. The IFNL3/4 ΔG variant increases susceptibility to cytomegalovirus retinitis among HIV-infected patients. AIDS 2014; 28: 1885-1889.
    • (2014) AIDS , vol.28 , pp. 1885-1889
    • Bibert, S.1    Wojtowicz, A.2    Taffé, P.3    Manuel, O.4    Bernasconi, E.5    Furrer, H.6
  • 51
    • 84924359602 scopus 로고    scopus 로고
    • Influence of IFNL3/4 polymorphisms on the incidence of cytomegalovirus infection after solid-organ transplantation
    • Manuel O, Wójtowicz A, Bibert S, Mueller NJ, van Delden C, Hirsch HH et al. Influence of IFNL3/4 polymorphisms on the incidence of cytomegalovirus infection after solid-organ transplantation. J Infect Dis 2015; 211: 906-914.
    • (2015) J Infect Dis , vol.211 , pp. 906-914
    • Manuel, O.1    Wójtowicz, A.2    Bibert, S.3    Mueller, N.J.4    Van Delden, C.5    Hirsch, H.H.6
  • 52
    • 84862180818 scopus 로고    scopus 로고
    • Development of tropical spastic paraparesis in human T-lymphotropic virus type 1 carriers is influenced by interleukin 28B gene polymorphisms
    • Treviño A, Lopez M, Vispo E, Aquilera A, Ramos JM, Benito R. Development of tropical spastic paraparesis in human T-lymphotropic virus type 1 carriers is influenced by interleukin 28B gene polymorphisms. Clin Infect Dis 2012; 55: e1-e4.
    • (2012) Clin Infect Dis , vol.55 , pp. e1-e4
    • Treviño, A.1    Lopez, M.2    Vispo, E.3    Aquilera, A.4    Ramos, J.M.5    Benito, R.6
  • 54
    • 84872566566 scopus 로고    scopus 로고
    • Lack of evidence to support the association of a single IL28B genotype SNP rs12979860 with the HTLV-1 clinical outcomes and proviral load
    • Sanabani SS, Nukui Y, Pereira J, de Costa AC, de Oliveira AC, Pessôa R et al. Lack of evidence to support the association of a single IL28B genotype SNP rs12979860 with the HTLV-1 clinical outcomes and proviral load. BMC Infect Dis 2012; 12: 374.
    • (2012) BMC Infect Dis , vol.12 , pp. 374
    • Sanabani, S.S.1    Nukui, Y.2    Pereira, J.3    De Costa, A.C.4    De Oliveira, A.C.5    Pessôa, R.6
  • 55
    • 84947483813 scopus 로고    scopus 로고
    • HTLV-1-associated myelopathy/tropical spastic paraparesis is not associated with SNP rs12979860 of the IL-28B gene
    • Vallinoto AC, Santana BB, Sá KS, Ferreira TC, Sousa RC, Azevedo VN et al. HTLV-1-associated myelopathy/tropical spastic paraparesis is not associated with SNP rs12979860 of the IL-28B gene. Mediators Inflamm 2015; 2015: 804167.
    • (2015) Mediators Inflamm , vol.2015 , pp. 804167
    • Vallinoto, A.C.1    Santana, B.B.2    Sá, K.S.3    Ferreira, T.C.4    Sousa, R.C.5    Azevedo, V.N.6
  • 56
    • 84946423327 scopus 로고    scopus 로고
    • IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy
    • de Sá KS, Santana BB, de Souza Ferreira TC, Sousa RC, Caldas CA, Azevedo VN et al. IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy. Cytokine 2016; 77: 79-87.
    • (2016) Cytokine , vol.77 , pp. 79-87
    • De Sá, K.S.1    Santana, B.B.2    De Souza-Ferreira, T.C.3    Sousa, R.C.4    Caldas, C.A.5    Azevedo, V.N.6
  • 57
    • 84857022067 scopus 로고    scopus 로고
    • Paradoxical expression of IL-28B mRNA in peripheral blood in human T-cell leukemia virus type-1 mono-infection and co-infection with hepatitis C virus
    • Kamihira S, Usui T, Ichikawa T, Ono N, Morinaga Y, Mori S et al. Paradoxical expression of IL-28B mRNA in peripheral blood in human T-cell leukemia virus type-1 mono-infection and co-infection with hepatitis C virus. Virol J 2012; 9: 40.
    • (2012) Virol J , vol.9 , pp. 40
    • Kamihira, S.1    Usui, T.2    Ichikawa, T.3    Ono, N.4    Morinaga, Y.5    Mori, S.6
  • 58
    • 84979235473 scopus 로고    scopus 로고
    • Absence of association of IFNL3/IL28B rs 12979860 and IFNL4 ss 469415590 polymorphisms with the neurological status of HTLV-1 Afro-Caribbean subjects in Martinique
    • Jeannin S, Costa JM, Poveda JD, Belrose G, Lezin A, Cabie A et al. Absence of association of IFNL3/IL28B rs 12979860 and IFNL4 ss 469415590 polymorphisms with the neurological status of HTLV-1 Afro-Caribbean subjects in Martinique. Retrovirology 2015; 2(Suppl 1): P 61.
    • (2015) Retrovirology , vol.2 , pp. 61
    • Jeannin, S.1    Costa, J.M.2    Poveda, J.D.3    Belrose, G.4    Lezin, A.5    Cabie, A.6
  • 59
    • 84979284699 scopus 로고    scopus 로고
    • Nucleic acid sensors involved in the recognition of HBV in the liver-specific in vivo transfection mouse models-Pattern recognition receptors and sensors for HBV
    • Leong CR, Oshiumi H, Suzuki T, Matsumoto M, Seya T. Nucleic acid sensors involved in the recognition of HBV in the liver-specific in vivo transfection mouse models-Pattern recognition receptors and sensors for HBV. Med Sci 2015; 3: 16-24.
    • (2015) Med Sci , vol.3 , pp. 16-24
    • Leong, C.R.1    Oshiumi, H.2    Suzuki, T.3    Matsumoto, M.4    Seya, T.5
  • 60
    • 84880285547 scopus 로고    scopus 로고
    • Regulation of hepatic innate immunity by hepatitis C virus
    • Horner Jr SM, Gale M. Regulation of hepatic innate immunity by hepatitis C virus. Nat Med 2013; 19: 879-888.
    • (2013) Nat Med , vol.19 , pp. 879-888
    • Horner, S.M.1    Gale, M.2
  • 61
    • 84894562959 scopus 로고    scopus 로고
    • Systematic review with meta-analysis: Do interferon lambda 3 polymorphisms predict the outcome of interferon-therapy in hepatitis B infection?
    • Galmozzi E, Viganó M, Lampertico P. Systematic review with meta-analysis: do interferon lambda 3 polymorphisms predict the outcome of interferon-therapy in hepatitis B infection? Aliment. Pharmacol Ther 2014; 39: 569-578.
    • (2014) Aliment. Pharmacol Ther , vol.39 , pp. 569-578
    • Galmozzi, E.1    Viganó, M.2    Lampertico, P.3
  • 62
    • 84874462216 scopus 로고    scopus 로고
    • One more piece in the interleukin 28B gene puzzle? The case of hepatitis B
    • Jilg N, Chung RT. One more piece in the interleukin 28B gene puzzle? The case of hepatitis B. Hepatology 2013; 57: 870-872.
    • (2013) Hepatology , vol.57 , pp. 870-872
    • Jilg, N.1    Chung, R.T.2
  • 63
    • 84909579830 scopus 로고    scopus 로고
    • Interleukin 28B genetic polymorphism and hepatitis B virus infection
    • Takahashi T. Interleukin 28B genetic polymorphism and hepatitis B virus infection. World J Gastroenterol 2014; 20: 12026-12030.
    • (2014) World J Gastroenterol , vol.20 , pp. 12026-12030
    • Takahashi, T.1
  • 65
    • 84908111464 scopus 로고    scopus 로고
    • Effects of polymorphisms in interferon λ3 (interleukin 28B) on sustained virologic response to therapy in patients with chronic hepatitis D virus infection
    • Yilmaz E, Baran B, Soyer OM, Onel M, Onel D, Ormeci AC et al. Effects of polymorphisms in interferon λ3 (interleukin 28B) on sustained virologic response to therapy in patients with chronic hepatitis D virus infection. Clin Gastroenterol Hepatol 2014; 12: 1753-1758.
    • (2014) Clin Gastroenterol Hepatol , vol.12 , pp. 1753-1758
    • Yilmaz, E.1    Baran, B.2    Soyer, O.M.3    Onel, M.4    Onel, D.5    Ormeci, A.C.6
  • 66
    • 77954348400 scopus 로고    scopus 로고
    • Hepatitis C infection in HIV-1 viral suppressors
    • Sajadi MM, Shakeri N, Talwani R, Redfield RR. Hepatitis C infection in HIV-1 viral suppressors. AIDS 2010; 24: 1689-1695.
    • (2010) AIDS , vol.24 , pp. 1689-1695
    • Sajadi, M.M.1    Shakeri, N.2    Talwani, R.3    Redfield, R.R.4
  • 68
    • 78649619461 scopus 로고    scopus 로고
    • IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection
    • Martin MP, Qi Y, Goedert JJ, Hussain SK, Kirk GD, Hoots WK et al. IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection. J Infect Dis 2010; 202: 1749-1753.
    • (2010) J Infect Dis , vol.202 , pp. 1749-1753
    • Martin, M.P.1    Qi, Y.2    Goedert, J.J.3    Hussain, S.K.4    Kirk, G.D.5    Hoots, W.K.6
  • 69
    • 78650883762 scopus 로고    scopus 로고
    • Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline
    • Rallon NI, Restrepo C, Naggie S, Lopez M, Del Romero J, Goldstein D et al. Interleukin-28B gene polymorphisms do not influence the susceptibility to HIV-infection or CD4 cell decline. AIDS 2011; 25: 269-271.
    • (2011) AIDS , vol.25 , pp. 269-271
    • Rallon, N.I.1    Restrepo, C.2    Naggie, S.3    Lopez, M.4    Del Romero, J.5    Goldstein, D.6
  • 70
    • 79551578079 scopus 로고    scopus 로고
    • Protective interleukin-28B genotype affects hepatitis C virus clearance, but does not contribute to HIV-1 control in a cohort of African-American elite controllers/suppressors
    • Salgado M, Kirk GD, Cox A, Rutebemberwa A, Huggins Y, Astemborski J et al. Protective interleukin-28B genotype affects hepatitis C virus clearance, but does not contribute to HIV-1 control in a cohort of African-American elite controllers/suppressors. AIDS 2011; 25: 385-387.
    • (2011) AIDS , vol.25 , pp. 385-387
    • Salgado, M.1    Kirk, G.D.2    Cox, A.3    Rutebemberwa, A.4    Huggins, Y.5    Astemborski, J.6
  • 74
    • 84975108685 scopus 로고    scopus 로고
    • IFNL4 rs368234815 polymorphism is associated with innate resistance to HIV-1 infection
    • Real LM, Herrero R, Rivero-Juárez A, Camacho A, Macías J, Vic S et al. IFNL4 rs368234815 polymorphism is associated with innate resistance to HIV-1 infection. AIDS 2015; 29: 1895-1897.
    • (2015) AIDS , vol.29 , pp. 1895-1897
    • Real, L.M.1    Herrero, R.2    Rivero-Juárez, A.3    Camacho, A.4    Macías, J.5    Vic, S.6
  • 75
    • 84883428456 scopus 로고    scopus 로고
    • A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication
    • Griffiths SJ, Koegl M, Boutell C, Zenner HL, Crump CM, Pica F et al. A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication. PLoS Pathog 2013; 9: e1003514.
    • (2013) PLoS Pathog , vol.9 , pp. e1003514
    • Griffiths, S.J.1    Koegl, M.2    Boutell, C.3    Zenner, H.L.4    Crump, C.M.5    Pica, F.6
  • 76
    • 84947295110 scopus 로고    scopus 로고
    • Interferon lambda 4 genotype is not associated with recurrence of oral or genital herpes
    • Lang Kuhs KA, Kuniholm MH, Pfeiffer RM, Chen S, Desai S, Edlin BR et al. Interferon lambda 4 genotype is not associated with recurrence of oral or genital herpes. PLoS One 2015; 10: e0138827.
    • (2015) PLoS One , vol.10 , pp. e0138827
    • Lang Kuhs, K.A.1    Kuniholm, M.H.2    Pfeiffer, R.M.3    Chen, S.4    Desai, S.5    Edlin, B.R.6
  • 77
    • 84861201337 scopus 로고    scopus 로고
    • IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with nonalcoholic fatty liver disease
    • Petta S, Grimaudo S, Cammá C, Cabibi D, Di Marco V, Licata G et al. IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with nonalcoholic fatty liver disease. J Hepatol 2012; 56: 1356-1362.
    • (2012) J Hepatol , vol.56 , pp. 1356-1362
    • Petta, S.1    Grimaudo, S.2    Cammá, C.3    Cabibi, D.4    Di Marco, V.5    Licata, G.6
  • 78
    • 79952425482 scopus 로고    scopus 로고
    • Genome wideassociation study identifies IL28B polymorphism to be associated with baseline Alt and hepatic necro-inflammatory activity in chronic hepatitis C patients enrolled in the ideal study
    • Thompson AJ, Clark PJ, Zhu M, Zhu Q, Ge D, Sulkowski MS et al. Genome wideassociation study identifies IL28B polymorphism to be associated with baseline Alt and hepatic necro-inflammatory activity in chronic hepatitis C patients enrolled in the ideal study. Hepatology 2010; 52: 1220 A-1221 A.
    • (2010) Hepatology , vol.52 , pp. 1220-1221
    • Thompson, A.J.1    Clark, P.J.2    Zhu, M.3    Zhu, Q.4    Ge, D.5    Sulkowski, M.S.6
  • 79
    • 84872379217 scopus 로고    scopus 로고
    • IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian north American patients
    • Garrett ME, Abdelmalek MF, Ashley-Koch A, Hauser MA, Moylan CA, Pang H et al. IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian north American patients. J Hepatol 2013; 58: 402-403.
    • (2013) J Hepatol , vol.58 , pp. 402-403
    • Garrett, M.E.1    Abdelmalek, M.F.2    Ashley-Koch, A.3    Hauser, M.A.4    Moylan, C.A.5    Pang, H.6
  • 80
    • 84872382244 scopus 로고    scopus 로고
    • Reply to: "iL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of caucasian North American patients"
    • Petta S, Craxi A. Reply to: "IL28B rs12979860 is not associated with histologic features of NAFLD in a cohort of Caucasian north American patients". J Hepatol 2013; 58: 403-404.
    • (2013) J Hepatol , vol.58 , pp. 403-404
    • Petta, S.1    Craxi, A.2
  • 81
    • 84924362729 scopus 로고    scopus 로고
    • Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease
    • Eslam M, Hashem AM, Leung R, Romero-Gomez M, Berg T, Dore GJ et al. Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nat Commun 2015; 6: 6422.
    • (2015) Nat Commun , vol.6 , pp. 6422
    • Eslam, M.1    Hashem, A.M.2    Leung, R.3    Romero-Gomez, M.4    Berg, T.5    Dore, G.J.6
  • 83
    • 84879118789 scopus 로고    scopus 로고
    • Anti-viral agents: Potential utility in exacerbations of asthma
    • Dhariwal J, Edwards MR, Johnston SL. Anti-viral agents: potential utility in exacerbations of asthma. Curr Opin Pharmacol 2013; 13: 331-336.
    • (2013) Curr Opin Pharmacol , vol.13 , pp. 331-336
    • Dhariwal, J.1    Edwards, M.R.2    Johnston, S.L.3
  • 84
    • 84859442243 scopus 로고    scopus 로고
    • Evaluation of interleukin 28B single nucleotide polymorphisms in infants suffering from bronchiolitis
    • Scagnolari C, Midulla F, Riva E, Monteleone K, Solimini A, Bonci E et al. Evaluation of interleukin 28B single nucleotide polymorphisms in infants suffering from bronchiolitis. Virus Res 2012; 165: 236-240.
    • (2012) Virus Res , vol.165 , pp. 236-240
    • Scagnolari, C.1    Midulla, F.2    Riva, E.3    Monteleone, K.4    Solimini, A.5    Bonci, E.6
  • 86
  • 88
    • 84881658991 scopus 로고    scopus 로고
    • Interferon induction and function at the mucosal surface
    • Durbin RK, Kotenko SV, Durbin JE. Interferon induction and function at the mucosal surface. Immunol Rev 2013; 255: 25-39.
    • (2013) Immunol Rev , vol.255 , pp. 25-39
    • Durbin, R.K.1    Kotenko, S.V.2    Durbin, J.E.3
  • 89
    • 84954142118 scopus 로고    scopus 로고
    • Roles for transcription factors Sp1, NF-κB, IRF3, and IRF7 in expression of the human IFNL4 gene
    • Chinnaswamy S, Bhushan A, Behera AK, Ghosh S, Rampurkar V, Chandra V et al. Roles for transcription factors Sp1, NF-κB, IRF3, and IRF7 in expression of the human IFNL4 gene. Viral Immunol 2016; 29: 49-63.
    • (2016) Viral Immunol , vol.29 , pp. 49-63
    • Chinnaswamy, S.1    Bhushan, A.2    Behera, A.K.3    Ghosh, S.4    Rampurkar, V.5    Chandra, V.6
  • 90
    • 84880688112 scopus 로고    scopus 로고
    • IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction
    • Bibert S, Roger T, Calandra T, Bochud M, Cerny A, Semmo N et al. IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction. J Exp Med 2013; 210: 1109-1116.
    • (2013) J Exp Med , vol.210 , pp. 1109-1116
    • Bibert, S.1    Roger, T.2    Calandra, T.3    Bochud, M.4    Cerny, A.5    Semmo, N.6
  • 91
    • 80052153278 scopus 로고    scopus 로고
    • Identification of improved IL28B SNPs and haplotypes for prediction of drug response inn treatment of hepatitis C using massively parallel sequencing in a crosssectional European cohort
    • Smith KR, Suppiah V, O'Connor K, Berg T, Weltman M, Abate ML et al. Identification of improved IL28B SNPs and haplotypes for prediction of drug response inn treatment of hepatitis C using massively parallel sequencing in a crosssectional European cohort. Genome Med 2011; 3: 57.
    • (2011) Genome Med , vol.3 , pp. 57
    • Smith, K.R.1    Suppiah, V.2    O'Connor, K.3    Berg, T.4    Weltman, M.5    Abate, M.L.6
  • 92
    • 84893430467 scopus 로고    scopus 로고
    • Interferon-λ4 (IFNL4) transcript expression in human liver tissue samples
    • Amanzada A, Kopp W, Spengler U, Ramadori G, Mihm S. Interferon-λ4 (IFNL4) transcript expression in human liver tissue samples. PLoS One 2013; 8: e84026.
    • (2013) PLoS One , vol.8 , pp. e84026
    • Amanzada, A.1    Kopp, W.2    Spengler, U.3    Ramadori, G.4    Mihm, S.5
  • 93
    • 84928317740 scopus 로고    scopus 로고
    • Impaired induction of interleukin 28B and expression of interferon λ4 associated with nonresponse to interferon-based therapy in chronic hepatitis C
    • Murakawa M, Asahina Y, Nakagawa M, Sakamoto N, Nitta S, Kusano-Kitazume A et al. Impaired induction of interleukin 28B and expression of interferon λ4 associated with nonresponse to interferon-based therapy in chronic hepatitis C. J Gastroenterol Hepatol 2015; 30: 1075-1084.
    • (2015) J Gastroenterol Hepatol , vol.30 , pp. 1075-1084
    • Murakawa, M.1    Asahina, Y.2    Nakagawa, M.3    Sakamoto, N.4    Nitta, S.5    Kusano-Kitazume, A.6
  • 94
    • 84937816422 scopus 로고    scopus 로고
    • Hepatic expression levels of interferons and interferon-stimulated genes in patients with chronic hepatitis C: A phenotype-genotype correlation study
    • Noureddin M, Rotman Y, Zhang F, Park H, Rehermann B, Thomas E et al. Hepatic expression levels of interferons and interferon-stimulated genes in patients with chronic hepatitis C: a phenotype-genotype correlation study. Genes Immun 2015; 16: 321-329.
    • (2015) Genes Immun , vol.16 , pp. 321-329
    • Noureddin, M.1    Rotman, Y.2    Zhang, F.3    Park, H.4    Rehermann, B.5    Thomas, E.6
  • 95
    • 84901057804 scopus 로고    scopus 로고
    • Interferon-lambda4 genetic polymorphism is associated with the therapy response for hepatitis C virus recurrence after a living donor liver transplant
    • Konishi H, Motomura T, Matsumoto Y, Harimoto N, Ikegami T, Yoshizumi T et al. Interferon-lambda4 genetic polymorphism is associated with the therapy response for hepatitis C virus recurrence after a living donor liver transplant. J Viral Hepat 2014; 21: 397-404.
    • (2014) J Viral Hepat , vol.21 , pp. 397-404
    • Konishi, H.1    Motomura, T.2    Matsumoto, Y.3    Harimoto, N.4    Ikegami, T.5    Yoshizumi, T.6
  • 96
    • 84896740050 scopus 로고    scopus 로고
    • Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes
    • Honda M, Shirasaki T, Shimakami T, Sakai A, Horii R, Arai K et al. Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes. Hepatology 2014; 59: 828-838.
    • (2014) Hepatology , vol.59 , pp. 828-838
    • Honda, M.1    Shirasaki, T.2    Shimakami, T.3    Sakai, A.4    Horii, R.5    Arai, K.6
  • 97
    • 84885091523 scopus 로고    scopus 로고
    • A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB mediated gene transcription
    • Chinnaswamy S, Chatterjee S, Boopathi R, Mukherjee S, Bhattacharjee S, Kundu SK. A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB mediated gene transcription. PLoS One 2013; 8: e75495.
    • (2013) PLoS One , vol.8 , pp. e75495
    • Chinnaswamy, S.1    Chatterjee, S.2    Boopathi, R.3    Mukherjee, S.4    Bhattacharjee, S.5    Kundu, S.K.6
  • 98
    • 84890951661 scopus 로고    scopus 로고
    • The favourable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced micro RNAs
    • McFarland AP, Horner SM, Jarret A, Joslyn RC, Bindewald E, Shapiro BA et al. The favourable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced micro RNAs. Nat Immunol 2014; 15: 72-79.
    • (2014) Nat Immunol , vol.15 , pp. 72-79
    • McFarland, A.P.1    Horner, S.M.2    Jarret, A.3    Joslyn, R.C.4    Bindewald, E.5    Shapiro, B.A.6
  • 99
    • 79955102638 scopus 로고    scopus 로고
    • Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance
    • du lulio J, Ciuffi A, Fitzmaurice K, Kelleher D, Rotger M, Fellay J et al. Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance. Hepatology 2011; 53: 1446-1454.
    • (2011) Hepatology , vol.53 , pp. 1446-1454
    • Du lulio, J.1    Ciuffi, A.2    Fitzmaurice, K.3    Kelleher, D.4    Rotger, M.5    Fellay, J.6
  • 100
    • 84946204708 scopus 로고    scopus 로고
    • IFNL3 mRNA structure is remodelled by a functional non-coding polymorphism associated with hepatitis C virus clearance
    • Lu YF, Mauger DM, Goldstein DB, Urban TJ, Weeks KM, Bradrick SS. IFNL3 mRNA structure is remodelled by a functional non-coding polymorphism associated with hepatitis C virus clearance. Sci Rep 2015; 5: 16037.
    • (2015) Sci Rep , vol.5 , pp. 16037
    • Lu, Y.F.1    Mauger, D.M.2    Goldstein, D.B.3    Urban, T.J.4    Weeks, K.M.5    Bradrick, S.S.6
  • 101
    • 80055029005 scopus 로고    scopus 로고
    • Genetic variation of the IL-28B promoter affecting gene expression
    • Sugiyama M, Tanaka Y, Wakita T, Nakanishi M, Mizokami M. Genetic variation of the IL-28B promoter affecting gene expression. PLoS One 2011; 6: e26620.
    • (2011) PLoS One , vol.6 , pp. e26620
    • Sugiyama, M.1    Tanaka, Y.2    Wakita, T.3    Nakanishi, M.4    Mizokami, M.5
  • 102
    • 84929095185 scopus 로고    scopus 로고
    • Prevalence of thymine-adenine dinucleotide repeat, IL28B and IFNL4 in Thai population and correlation with spontaneous clearance and treatment outcome of hepatitis C infection
    • Thong VD, Wasitthankasem R, Tangkijvanich P, Vongpunsawad S, Poovorawan Y. Prevalence of thymine-adenine dinucleotide repeat, IL28B and IFNL4 in Thai population and correlation with spontaneous clearance and treatment outcome of hepatitis C infection. PLoS One 2015; 10: e0125400.
    • (2015) PLoS One , vol.10 , pp. e0125400
    • Thong, V.D.1    Wasitthankasem, R.2    Tangkijvanich, P.3    Vongpunsawad, S.4    Poovorawan, Y.5
  • 103
    • 84929030416 scopus 로고    scopus 로고
    • Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C
    • Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N et al. Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C. J Gastroenterol Hepatol 2014; 29: 1996-2005.
    • (2014) J Gastroenterol Hepatol , vol.29 , pp. 1996-2005
    • Masaki, N.1    Sugiyama, M.2    Shimada, N.3    Tanaka, Y.4    Nakamuta, M.5    Izumi, N.6
  • 104
    • 84943199680 scopus 로고    scopus 로고
    • A thymineadenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus
    • Hiramine S, Sugiyama M, Furusyo N, Uto H, Ido A, Tsubouchi H et al. A thymineadenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus. J Gastroenterol 2015; 50: 1069-1077.
    • (2015) J Gastroenterol , vol.50 , pp. 1069-1077
    • Hiramine, S.1    Sugiyama, M.2    Furusyo, N.3    Uto, H.4    Ido, A.5    Tsubouchi, H.6
  • 105
    • 84973875527 scopus 로고    scopus 로고
    • IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes
    • Kurbanov F, Kim Y, Latanich R, Chaudhari P, El-Diwany R, Knabel M et al. IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes. Antivir Ther 2015; 20: 805-814.
    • (2015) Antivir Ther , vol.20 , pp. 805-814
    • Kurbanov, F.1    Kim, Y.2    Latanich, R.3    Chaudhari, P.4    El-Diwany, R.5    Knabel, M.6
  • 106
    • 84936848014 scopus 로고    scopus 로고
    • Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes
    • Terczyńska-Dyla E, Bibert S, Duong FH, Krol I, Jørgensen S, Collinet E et al. Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nat Commun 2014; 5: 5699.
    • (2014) Nat Commun , vol.5 , pp. 5699
    • Terczyńska-Dyla, E.1    Bibert, S.2    Duong, F.H.3    Krol, I.4    Jørgensen, S.5    Collinet, E.6
  • 107
  • 108
    • 84861370971 scopus 로고    scopus 로고
    • IL-28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population
    • Shi X, Pan Y, Wang M, Wang D, Li W, Jiang T et al. IL-28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population. PLoS One 2012; 7: e37054.
    • (2012) PLoS One , vol.7 , pp. e37054
    • Shi, X.1    Pan, Y.2    Wang, M.3    Wang, D.4    Li, W.5    Jiang, T.6
  • 109
    • 84859620461 scopus 로고    scopus 로고
    • Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV
    • Rallón NI, Soriano V, Naggie S, Restrepo C, Hutchison J, Vispo E et al. Impact of IL28B gene polymorphisms on interferon-λ3 plasma levels during pegylated interferon-α/ribavirin therapy for chronic hepatitis C in patients coinfected with HIV. J Antimicrob Chemother 2012; 67: 1246-1249.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 1246-1249
    • Rallón, N.I.1    Soriano, V.2    Naggie, S.3    Restrepo, C.4    Hutchison, J.5    Vispo, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.