Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations

Genome Research

Volumn 26, Issue 6, 2016, Pages 719-731

  Taberlay, Phillippa C ^a,b   Achinger Kawecka, Joanna ^a,b   Lun, Aaron T L ^c,d   Buske, Fabian A ^a   Sabir, Kenneth ^a   Gould, Cathryn M ^a   Zotenko, Elena ^a,b   Bert, Saul A ^a   Giles, Katherine A ^a   Bauer, Denis C ^e   Smyth, Gordon K ^c,d   Stirzaker, Clare ^a,b   O'Donoghue, Sean I ^a,e   Clark, Susan J ^a,b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR CTCF; CCCTC-BINDING FACTOR; CHROMATIN; HISTONE; PROTEIN BINDING; REPRESSOR PROTEIN;

ARTICLE; CANCER CELL; CANCER GENETICS; CELL INTERACTION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; CHROMOSOME DELETION; COPY NUMBER VARIATION; ENHANCER REGION; EPIGENETICS; FEMALE; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENE SILENCING; HISTONE MODIFICATION; HUMAN; HUMAN CELL; OVERLAPPING GENE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM CELL; RECURRENCE FREE SURVIVAL; TRANSCRIPTION INITIATION SITE; CHROMATIN; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; METABOLISM; MOLECULAR GENETICS; NEOPLASM; PHYSIOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

CELL LINE, TUMOR; CHROMATIN; ENHANCER ELEMENTS, GENETIC; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HISTONES; HUMANS; MOLECULAR SEQUENCE ANNOTATION; NEOPLASMS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPRESSOR PROTEINS;

EID: 84973305064     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.201517.115     Document Type: Article

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