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Volumn 99, Issue 2, 2008, Pages 375-382

DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma

Author keywords

DLEC1; Mismatch repair; NSCLC; Prognosis; Promoter methylation

Indexed keywords

DNA; PROTEIN MLH1; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; RETINOID X RECEPTOR BETA; DLEC1 PROTEIN, HUMAN; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; RASSF1 PROTEIN, HUMAN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR BETA; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN; ZMYND10 PROTEIN, HUMAN;

EID: 48249117114     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604452     Document Type: Article
Times cited : (95)

References (40)
  • 3
    • 0031807019 scopus 로고    scopus 로고
    • High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer
    • Benachenhou N, Guiral S, Gorska-Flipot I, Labuda D, Sinnett D (1998) High resolution deletion mapping reveals frequent allelic losses at the DNA mismatch repair loci hMLH1 and hMSH3 in non-small cell lung cancer. Int J Cancer 77: 173-180
    • (1998) Int J Cancer , vol.77 , pp. 173-180
    • Benachenhou, N.1    Guiral, S.2    Gorska-Flipot, I.3    Labuda, D.4    Sinnett, D.5
  • 4
    • 20844444590 scopus 로고    scopus 로고
    • RASSF1A is not appropriate as an early detection marker or a prognostic marker for non-small cell lung cancer
    • Choi N, Son DS, Song I, Lee HS, Lim YS, Song MS, Lim DS, Lee J, Kim H, Kim J (2005) RASSF1A is not appropriate as an early detection marker or a prognostic marker for non-small cell lung cancer. Int J Cancer 115: 575-581
    • (2005) Int J Cancer , vol.115 , pp. 575-581
    • Choi, N.1    Son, D.S.2    Song, I.3    Lee, H.S.4    Lim, Y.S.5    Song, M.S.6    Lim, D.S.7    Lee, J.8    Kim, H.9    Kim, J.10
  • 6
    • 0033561527 scopus 로고    scopus 로고
    • Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3
    • Daigo Y, Nishiwaki T, Kawasoe T, Tamari M, Tsuchiya E, Nakamura Y (1999) Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3. Cancer Res 59: 1966-1972
    • (1999) Cancer Res , vol.59 , pp. 1966-1972
    • Daigo, Y.1    Nishiwaki, T.2    Kawasoe, T.3    Tamari, M.4    Tsuchiya, E.5    Nakamura, Y.6
  • 7
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP (2000) Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nature Genet 25: 315-319
    • (2000) Nature Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 8
    • 0033563083 scopus 로고    scopus 로고
    • CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
    • Eads CA, Danenberg KD, Kawakami K, Saltz LB, Danenberg PV, Laird PW (1999) CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res 59: 2302-2306
    • (1999) Cancer Res , vol.59 , pp. 2302-2306
    • Eads, C.A.1    Danenberg, K.D.2    Kawakami, K.3    Saltz, L.B.4    Danenberg, P.V.5    Laird, P.W.6
  • 9
    • 0032894125 scopus 로고    scopus 로고
    • Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
    • Esteller M, Sanchez-Cespedes M, Rosell R, Sidransky D, Baylin SB, Herman JG (1999) Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 59: 67-70
    • (1999) Cancer Res , vol.59 , pp. 67-70
    • Esteller, M.1    Sanchez-Cespedes, M.2    Rosell, R.3    Sidransky, D.4    Baylin, S.B.5    Herman, J.G.6
  • 10
    • 33646369393 scopus 로고    scopus 로고
    • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
    • Frigola J, Song J, Stirzaker C, Hinshelwood RA, Peinado MA, Clark SJ (2006) Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nature Genet 38: 540-549
    • (2006) Nature Genet , vol.38 , pp. 540-549
    • Frigola, J.1    Song, J.2    Stirzaker, C.3    Hinshelwood, R.A.4    Peinado, M.A.5    Clark, S.J.6
  • 11
    • 0036890489 scopus 로고    scopus 로고
    • Current concepts in the staging of non-small cell lung cancer
    • Grondin SC, Liptay MJ (2002) Current concepts in the staging of non-small cell lung cancer. Surg Oncol 11: 181-190
    • (2002) Surg Oncol , vol.11 , pp. 181-190
    • Grondin, S.C.1    Liptay, M.J.2
  • 13
    • 23044491195 scopus 로고    scopus 로고
    • Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer
    • Hsu HS, Wen CK, Tang YA, Lin RK, Li WY, Hsu WH, Wang YC (2005) Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer. Clin Cancer Res 11: 5410-5416
    • (2005) Clin Cancer Res , vol.11 , pp. 5410-5416
    • Hsu, H.S.1    Wen, C.K.2    Tang, Y.A.3    Lin, R.K.4    Li, W.Y.5    Hsu, W.H.6    Wang, Y.C.7
  • 14
    • 0028815929 scopus 로고
    • Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma
    • Hung J, Kishimoto Y, Sugio K, Virmani A, McIntire DD, Minna JD, Gazdar AF (1995) Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma. JAMA 273: 558-563
    • (1995) JAMA , vol.273 , pp. 558-563
    • Hung, J.1    Kishimoto, Y.2    Sugio, K.3    Virmani, A.4    McIntire, D.D.5    Minna, J.D.6    Gazdar, A.F.7
  • 15
    • 0031588601 scopus 로고    scopus 로고
    • Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line
    • Ishikawa S, Kai M, Tamari M, Takei Y, Takeuchi K, Bandou H, Yamane Y, Ogawa M, Nakamura Y (1997) Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line. DNA Res 4: 35-43
    • (1997) DNA Res , vol.4 , pp. 35-43
    • Ishikawa, S.1    Kai, M.2    Tamari, M.3    Takei, Y.4    Takeuchi, K.5    Bandou, H.6    Yamane, Y.7    Ogawa, M.8    Nakamura, Y.9
  • 16
    • 21144446552 scopus 로고    scopus 로고
    • Frequent inactivation of RASSF1A, BLU, and SEMA3B on 3p21.3 by promoter hypermethylation and allele loss in non-small cell lung cancer
    • Ito M, Ito G, Kondo M, Uchiyama M, Fukui T, Mori S, Yoshioka H, Ueda Y, Shimokata K, Sekido Y (2005) Frequent inactivation of RASSF1A, BLU, and SEMA3B on 3p21.3 by promoter hypermethylation and allele loss in non-small cell lung cancer. Cancer Lett 225: 131-139
    • (2005) Cancer Lett , vol.225 , pp. 131-139
    • Ito, M.1    Ito, G.2    Kondo, M.3    Uchiyama, M.4    Fukui, T.5    Mori, S.6    Yoshioka, H.7    Ueda, Y.8    Shimokata, K.9    Sekido, Y.10
  • 17
    • 33644758237 scopus 로고    scopus 로고
    • Promoter hypermethylation of the O(6)-methylguanine DNA methyltransferase gene and microsatellite instability in metastatic melanoma
    • Kohonen-Corish MR, Cooper WA, Saab J, Thompson JF, Trent RJ, Millward MJ (2006) Promoter hypermethylation of the O(6)-methylguanine DNA methyltransferase gene and microsatellite instability in metastatic melanoma. J Inv Dermatol 126: 167-171
    • (2006) J Inv Dermatol , vol.126 , pp. 167-171
    • Kohonen-Corish, M.R.1    Cooper, W.A.2    Saab, J.3    Thompson, J.F.4    Trent, R.J.5    Millward, M.J.6
  • 21
    • 33646434223 scopus 로고    scopus 로고
    • Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer
    • Kwong J, Lee JY, Wong KK, Zhou X, Wong DT, Lo KW, Welch WR, Berkowitz RS, Mok SC (2006) Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer. Neoplasia 8: 268-278
    • (2006) Neoplasia , vol.8 , pp. 268-278
    • Kwong, J.1    Lee, J.Y.2    Wong, K.K.3    Zhou, X.4    Wong, D.T.5    Lo, K.W.6    Welch, W.R.7    Berkowitz, R.S.8    Mok, S.C.9
  • 22
    • 0036311221 scopus 로고    scopus 로고
    • Methylation sequencing from limiting DNA: Embryonic, fixed, and microdissected cells
    • Millar DS, Warnecke PM, Melki JR, Clark SJ (2002) Methylation sequencing from limiting DNA: embryonic, fixed, and microdissected cells. Methods 27: 108-113
    • (2002) Methods , vol.27 , pp. 108-113
    • Millar, D.S.1    Warnecke, P.M.2    Melki, J.R.3    Clark, S.J.4
  • 23
    • 21644444740 scopus 로고    scopus 로고
    • The profile of hMLH1 methylation and microsatellite instability in colorectal and non-small cell lung cancer
    • Okuda T, Kawakami K, Ishiguro K, Oda M, Omura K, Watanabe G (2005) The profile of hMLH1 methylation and microsatellite instability in colorectal and non-small cell lung cancer. Int J Mol Med 15: 85-90
    • (2005) Int J Mol Med , vol.15 , pp. 85-90
    • Okuda, T.1    Kawakami, K.2    Ishiguro, K.3    Oda, M.4    Omura, K.5    Watanabe, G.6
  • 26
    • 0036264815 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
    • Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA (2002) The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol Cell Biol 22: 4309-4318
    • (2002) Mol Cell Biol , vol.22 , pp. 4309-4318
    • Shivakumar, L.1    Minna, J.2    Sakamaki, T.3    Pestell, R.4    White, M.A.5
  • 31
    • 0034178010 scopus 로고    scopus 로고
    • RARbeta2 specificity in mediating RA inhibition of growth of lung cancer-derived cells
    • Toulouse A, Morin J, Dion PA, Houle B, Bradley WE (2000) RARbeta2 specificity in mediating RA inhibition of growth of lung cancer-derived cells. Lung Cancer 28: 127-137
    • (2000) Lung Cancer , vol.28 , pp. 127-137
    • Toulouse, A.1    Morin, J.2    Dion, P.A.3    Houle, B.4    Bradley, W.E.5
  • 33
  • 36
    • 19244370711 scopus 로고    scopus 로고
    • Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, Fondon III JW, Garner HR, McKay B, Latif F, Lerman MI, Lam S, Gazdar AF, Minna JD (2000) High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60: 1949-1960
    • Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, Fondon III JW, Garner HR, McKay B, Latif F, Lerman MI, Lam S, Gazdar AF, Minna JD (2000) High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60: 1949-1960
  • 38
    • 0042563143 scopus 로고    scopus 로고
    • Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers
    • Yanagawa N, Tamura G, Oizumi H, Takahashi N, Shimazaki Y, Motoyama T (2003) Promoter hypermethylation of tumor suppressor and tumor-related genes in non-small cell lung cancers. Cancer Sci 94: 589-592
    • (2003) Cancer Sci , vol.94 , pp. 589-592
    • Yanagawa, N.1    Tamura, G.2    Oizumi, H.3    Takahashi, N.4    Shimazaki, Y.5    Motoyama, T.6
  • 39
    • 0037037787 scopus 로고    scopus 로고
    • Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers
    • Zabarovsky ER, Lerman MI, Minna JD (2002) Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene 21: 6915-6935
    • (2002) Oncogene , vol.21 , pp. 6915-6935
    • Zabarovsky, E.R.1    Lerman, M.I.2    Minna, J.D.3


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