메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; HISTONE; CHROMATIN;

EID: 84939207207     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0719-9     Document Type: Article
Times cited : (40)

References (59)
  • 1
    • 84881086323 scopus 로고    scopus 로고
    • Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
    • Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer. 2013;13:497-510.
    • (2013) Nat Rev Cancer , vol.13 , pp. 497-510
    • Timp, W.1    Feinberg, A.P.2
  • 2
    • 34547765951 scopus 로고    scopus 로고
    • Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis
    • Clark SJ. Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet. 2007;16:R88-95.
    • (2007) Hum Mol Genet , vol.16 , pp. R88-95
    • Clark, S.J.1
  • 3
    • 77649271805 scopus 로고    scopus 로고
    • Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
    • Coolen MW, Stirzaker C, Song JZ, Statham AL, Kassir Z, Moreno CS, et al. Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity. Nat Cell Biol. 2010;12:235-46.
    • (2010) Nat Cell Biol , vol.12 , pp. 235-246
    • Coolen, M.W.1    Stirzaker, C.2    Song, J.Z.3    Statham, A.L.4    Kassir, Z.5    Moreno, C.S.6
  • 4
    • 84936863131 scopus 로고    scopus 로고
    • Neighboring genes show correlated evolution in gene expression
    • Ghanbarian AT, Hurst LD. Neighboring genes show correlated evolution in gene expression. Mol Biol Evol. 2015;32:1748-66.
    • (2015) Mol Biol Evol , vol.32 , pp. 1748-1766
    • Ghanbarian, A.T.1    Hurst, L.D.2
  • 5
    • 25844496592 scopus 로고    scopus 로고
    • The role of chromatin structure in regulating the expression of clustered genes
    • Sproul D, Gilbert N, Bickmore WA. The role of chromatin structure in regulating the expression of clustered genes. Nat Rev Genet. 2005;6:775-81.
    • (2005) Nat Rev Genet , vol.6 , pp. 775-781
    • Sproul, D.1    Gilbert, N.2    Bickmore, W.A.3
  • 6
    • 84882737017 scopus 로고    scopus 로고
    • Chromatin position effects assayed by thousands of reporters integrated in parallel
    • Akhtar W, de Jong J, Pindyurin AV, Pagie L, Meuleman W, de Ridder J, et al. Chromatin position effects assayed by thousands of reporters integrated in parallel. Cell. 2013;154:914-27.
    • (2013) Cell , vol.154 , pp. 914-927
    • Akhtar, W.1    Jong, J.2    Pindyurin, A.V.3    Pagie, L.4    Meuleman, W.5    Ridder, J.6
  • 7
    • 84861100147 scopus 로고    scopus 로고
    • Spatial partitioning of the regulatory landscape of the X-inactivation centre
    • Nora EP, Lajoie BR, Schulz EG, Giorgetti L, Okamoto I, Servant N, et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature. 2012;485:381-5.
    • (2012) Nature , vol.485 , pp. 381-385
    • Nora, E.P.1    Lajoie, B.R.2    Schulz, E.G.3    Giorgetti, L.4    Okamoto, I.5    Servant, N.6
  • 10
    • 33646369393 scopus 로고    scopus 로고
    • Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
    • Frigola J, Song J, Stirzaker C, Hinshelwood RA, Peinado MA, Clark SJ. Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nat Genet. 2006;38:540-9.
    • (2006) Nat Genet , vol.38 , pp. 540-549
    • Frigola, J.1    Song, J.2    Stirzaker, C.3    Hinshelwood, R.A.4    Peinado, M.A.5    Clark, S.J.6
  • 11
  • 12
    • 73649141296 scopus 로고    scopus 로고
    • Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor
    • Dallosso AR, Hancock AL, Szemes M, Moorwood K, Chilukamarri L, Tsai HH, et al. Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor. PLoS Genet. 2009;5:e1000745.
    • (2009) PLoS Genet , vol.5
    • Dallosso, A.R.1    Hancock, A.L.2    Szemes, M.3    Moorwood, K.4    Chilukamarri, L.5    Tsai, H.H.6
  • 13
    • 82455162772 scopus 로고    scopus 로고
    • Identification of DNA methylation changes associated with human gastric cancer
    • Park JH, Park J, Choi JK, Lyu J, Bae MG, Lee YG, et al. Identification of DNA methylation changes associated with human gastric cancer. BMC Med Genomics. 2011;4:82.
    • (2011) BMC Med Genomics , vol.4 , pp. 82
    • Park, J.H.1    Park, J.2    Choi, J.K.3    Lyu, J.4    Bae, M.G.5    Lee, Y.G.6
  • 14
    • 84867233454 scopus 로고    scopus 로고
    • Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways
    • Dallosso AR, Øster B, Greenhough A, Thorsen K, Curry TJ, Owen C, et al. Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways. Oncogene. 2012;31:4409-19.
    • (2012) Oncogene , vol.31 , pp. 4409-4419
    • Dallosso, A.R.1    Øster, B.2    Greenhough, A.3    Thorsen, K.4    Curry, T.J.5    Owen, C.6
  • 15
  • 16
    • 84892742949 scopus 로고    scopus 로고
    • PRC2-independent chromatin compaction and transcriptional repression in cancer
    • Vallot C, Hérault A, Boyle S, Bickmore WA, Radvanyi F. PRC2-independent chromatin compaction and transcriptional repression in cancer. Oncogene. 2015;34:741-51.
    • (2015) Oncogene , vol.34 , pp. 741-751
    • Vallot, C.1    Hérault, A.2    Boyle, S.3    Bickmore, W.A.4    Radvanyi, F.5
  • 20
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006;10:515-27.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 21
    • 77952966794 scopus 로고    scopus 로고
    • Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping
    • Hsu PY, Hsu HK, Singer GAC, Yan PS, Rodriguez BAT, Liu JC, et al. Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping. Genome Res. 2010;20:733-44.
    • (2010) Genome Res , vol.20 , pp. 733-744
    • Hsu, P.Y.1    Hsu, H.K.2    Singer, G.A.C.3    Yan, P.S.4    Rodriguez, B.A.T.5    Liu, J.C.6
  • 22
    • 78149477701 scopus 로고    scopus 로고
    • Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
    • Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Holm K, Hegardt C, et al. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics. Breast Cancer Res. 2010;12:R42.
    • (2010) Breast Cancer Res , vol.12 , pp. R42
    • Jönsson, G.1    Staaf, J.2    Vallon-Christersson, J.3    Ringnér, M.4    Holm, K.5    Hegardt, C.6
  • 24
    • 84882704380 scopus 로고    scopus 로고
    • Gene-specific transcriptional mechanisms at the histone gene cluster revealed by single-cell imaging
    • Guglielmi B, La Rochelle N, Tjian R. Gene-specific transcriptional mechanisms at the histone gene cluster revealed by single-cell imaging. Mol Cell. 2013;51:480-92.
    • (2013) Mol Cell , vol.51 , pp. 480-492
    • Guglielmi, B.1    Rochelle, N.2    Tjian, R.3
  • 26
    • 80455164549 scopus 로고    scopus 로고
    • Mediator-dependent nuclear receptor function
    • Chen W, Roeder RG. Mediator-dependent nuclear receptor function. Seminars Cell Develop Biol. 2011;22:749-58.
    • (2011) Seminars Cell Develop Biol , vol.22 , pp. 749-758
    • Chen, W.1    Roeder, R.G.2
  • 27
    • 84870886414 scopus 로고    scopus 로고
    • Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
    • Sotgia F, Whitaker-Menezes D, Martinez-Outschoorn UE, Salem AF, Tsirigos A, Lamb R, et al. Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. Cell Cycle. 2012;11:4390-401.
    • (2012) Cell Cycle , vol.11 , pp. 4390-4401
    • Sotgia, F.1    Whitaker-Menezes, D.2    Martinez-Outschoorn, U.E.3    Salem, A.F.4    Tsirigos, A.5    Lamb, R.6
  • 28
    • 74849113364 scopus 로고    scopus 로고
    • Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue
    • Chen DT, Nasir A, Culhane A, Venkataramu C, Fulp W, Rubio R, et al. Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue. Breast Cancer Res Treat. 2010;119:335-46.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 335-346
    • Chen, D.T.1    Nasir, A.2    Culhane, A.3    Venkataramu, C.4    Fulp, W.5    Rubio, R.6
  • 30
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98:10869-74.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sørlie, T.1    Perou, C.M.2    Tibshirani, R.3    Aas, T.4    Geisler, S.5    Johnsen, H.6
  • 31
    • 2442695407 scopus 로고    scopus 로고
    • Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription
    • Chambeyron S, Bickmore WA. Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev. 2004;18:1119-30.
    • (2004) Genes Dev , vol.18 , pp. 1119-1130
    • Chambeyron, S.1    Bickmore, W.A.2
  • 32
    • 77951947926 scopus 로고    scopus 로고
    • Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination
    • Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, et al. Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 2010;38:452-64.
    • (2010) Mol Cell , vol.38 , pp. 452-464
    • Eskeland, R.1    Leeb, M.2    Grimes, G.R.3    Kress, C.4    Boyle, S.5    Sproul, D.6
  • 33
    • 84880802221 scopus 로고    scopus 로고
    • FGF signalling regulates chromatin organisation during neural differentiation via mechanism(s) that can be uncoupled from transcription
    • Patel NS, Rhinn M, Halley PA, Dolle P, Bickmore WA, Storey KG. FGF signalling regulates chromatin organisation during neural differentiation via mechanism(s) that can be uncoupled from transcription. PLoS Genet. 2013;9:e1003614.
    • (2013) PLoS Genet , vol.9
    • Patel, N.S.1    Rhinn, M.2    Halley, P.A.3    Dolle, P.4    Bickmore, W.A.5    Storey, K.G.6
  • 34
    • 84884730929 scopus 로고    scopus 로고
    • Regional chromatin decompaction in Cornelia de Lange syndrome associated with NIPBL disruption can be uncoupled from cohesion and CTCF
    • Nolen LD, Boyle S, Ansari M, Pritchard E, Bickmore WA. Regional chromatin decompaction in Cornelia de Lange syndrome associated with NIPBL disruption can be uncoupled from cohesion and CTCF. Hum Mol Genet. 2013;22:4180-93.
    • (2013) Hum Mol Genet , vol.22 , pp. 4180-4193
    • Nolen, L.D.1    Boyle, S.2    Ansari, M.3    Pritchard, E.4    Bickmore, W.A.5
  • 35
    • 0025191263 scopus 로고
    • Characterization of the estrogen receptor in two antiestrogen-resistant cell lines, LY2 and T47D
    • Mullick A, Chambon P. Characterization of the estrogen receptor in two antiestrogen-resistant cell lines, LY2 and T47D. Cancer Res. 1990;50:333-8.
    • (1990) Cancer Res , vol.50 , pp. 333-338
    • Mullick, A.1    Chambon, P.2
  • 36
    • 0035177216 scopus 로고    scopus 로고
    • Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    • Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 2001;15:50-65.
    • (2001) Genes Dev , vol.15 , pp. 50-65
    • Elenbaas, B.1    Spirio, L.2    Koerner, F.3    Fleming, M.D.4    Zimonjic, D.B.5    Donaher, J.L.6
  • 38
    • 78651250284 scopus 로고    scopus 로고
    • FOXA1 is a key determinant of estrogen receptor function and endocrine response
    • Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet. 2011;43:27-33.
    • (2011) Nat Genet , vol.43 , pp. 27-33
    • Hurtado, A.1    Holmes, K.A.2    Ross-Innes, C.S.3    Schmidt, D.4    Carroll, J.S.5
  • 39
    • 33845605456 scopus 로고    scopus 로고
    • Hormonal regulation of PKC: estrogen up-regulates PKCeta expression in estrogen-responsive breast cancer cells
    • Karp G, Maissel A, Livneh E. Hormonal regulation of PKC: estrogen up-regulates PKCeta expression in estrogen-responsive breast cancer cells. Cancer Lett. 2007;246:173-81.
    • (2007) Cancer Lett , vol.246 , pp. 173-181
    • Karp, G.1    Maissel, A.2    Livneh, E.3
  • 40
    • 52949133457 scopus 로고    scopus 로고
    • The meaning of gene positioning
    • Takizawa T, Meaburn KJ, Misteli T. The meaning of gene positioning. Cell. 2008;135:9-13.
    • (2008) Cell , vol.135 , pp. 9-13
    • Takizawa, T.1    Meaburn, K.J.2    Misteli, T.3
  • 41
    • 0035253606 scopus 로고    scopus 로고
    • The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells
    • Boyle S, Gilchrist S, Bridger JM, Mahy NL, Ellis JA, Bickmore WA. The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet. 2001;10:211-9.
    • (2001) Hum Mol Genet , vol.10 , pp. 211-219
    • Boyle, S.1    Gilchrist, S.2    Bridger, J.M.3    Mahy, N.L.4    Ellis, J.A.5    Bickmore, W.A.6
  • 42
    • 84875190221 scopus 로고    scopus 로고
    • Genome architecture: domain organization of interphase chromosomes
    • Bickmore WA, van Steensel B. Genome architecture: domain organization of interphase chromosomes. Cell. 2013;152:1270-84.
    • (2013) Cell , vol.152 , pp. 1270-1284
    • Bickmore, W.A.1    Steensel, B.2
  • 43
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • Dixon JR, Selvaraj S, Yue F, Kim A, Li Y, Shen Y, et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature. 2012;485:376-80.
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1    Selvaraj, S.2    Yue, F.3    Kim, A.4    Li, Y.5    Shen, Y.6
  • 44
    • 84907512608 scopus 로고    scopus 로고
    • Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation
    • Le Dily F, Baù D, Pohl A, Vicent GP, Serra F, Soronellas D, et al. Distinct structural transitions of chromatin topological domains correlate with coordinated hormone-induced gene regulation. Genes Dev. 2014;28:2151-62.
    • (2014) Genes Dev , vol.28 , pp. 2151-2162
    • Dily, F.1    Baù, D.2    Pohl, A.3    Vicent, G.P.4    Serra, F.5    Soronellas, D.6
  • 45
    • 33845295138 scopus 로고    scopus 로고
    • Human heterochromatin proteins form large domains containing KRAB-ZNF genes
    • Vogel MJ, Guelen L, de Wit E, Peric-Hupkes D, Lodén M, Talhout W, et al. Human heterochromatin proteins form large domains containing KRAB-ZNF genes. Genome Res. 2006;16:1493-504.
    • (2006) Genome Res , vol.16 , pp. 1493-1504
    • Vogel, M.J.1    Guelen, L.2    Wit, E.3    Peric-Hupkes, D.4    Lodén, M.5    Talhout, W.6
  • 46
    • 84918510740 scopus 로고    scopus 로고
    • Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization
    • Williamson I, Berlivet S, Eskeland R, Boyle S, Illingworth RS, Paquette D, et al. Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization. Genes Dev. 2014;28:2778-91.
    • (2014) Genes Dev , vol.28 , pp. 2778-2791
    • Williamson, I.1    Berlivet, S.2    Eskeland, R.3    Boyle, S.4    Illingworth, R.S.5    Paquette, D.6
  • 49
    • 69249137029 scopus 로고    scopus 로고
    • Biological determinants of endocrine resistance in breast cancer
    • Musgrove EA, Sutherland RL. Biological determinants of endocrine resistance in breast cancer. Nat Rev Cancer. 2009;9:631-43.
    • (2009) Nat Rev Cancer , vol.9 , pp. 631-643
    • Musgrove, E.A.1    Sutherland, R.L.2
  • 50
    • 84896546116 scopus 로고    scopus 로고
    • Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance
    • Morrison G, Fu X, Shea M, Nanda S, Giuliano M, Wang T, et al. Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance. Breast Cancer Res Treat. 2014;144:263-72.
    • (2014) Breast Cancer Res Treat , vol.144 , pp. 263-272
    • Morrison, G.1    Fu, X.2    Shea, M.3    Nanda, S.4    Giuliano, M.5    Wang, T.6
  • 51
    • 84865190335 scopus 로고    scopus 로고
    • Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor aα target gene activation
    • Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, et al. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor aα target gene activation. Proc Natl Acad Sci U S A. 2012;109:13331-6.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13331-13336
    • Zhang, X.1    Bolt, M.2    Guertin, M.J.3    Chen, W.4    Zhang, S.5    Cherrington, B.D.6
  • 53
    • 84918539650 scopus 로고    scopus 로고
    • Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells
    • Therizols P, Illingworth RS, Courilleau C, Boyle S, Wood AJ, Bickmore WA. Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells. Science. 2014;346:1238-42.
    • (2014) Science , vol.346 , pp. 1238-1242
    • Therizols, P.1    Illingworth, R.S.2    Courilleau, C.3    Boyle, S.4    Wood, A.J.5    Bickmore, W.A.6
  • 55
    • 74049123435 scopus 로고    scopus 로고
    • Disease-specific gene repositioning in breast cancer. Disease-specific gene repositioning in breast cancer
    • Meaburn KJ, Gudla PR, Khan S, Lockett SJ, Misteli T. Disease-specific gene repositioning in breast cancer. Disease-specific gene repositioning in breast cancer. J Cell Biol. 2009;187:801-12.
    • (2009) J Cell Biol , vol.187 , pp. 801-812
    • Meaburn, K.J.1    Gudla, P.R.2    Khan, S.3    Lockett, S.J.4    Misteli, T.5
  • 57
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • Quinlan AR, Hall IM. BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics. 2010;26:841-2.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 58
    • 84939170621 scopus 로고    scopus 로고
    • BACPAC Resources Center. http://bacpac.chori.org/.
  • 59
    • 34248593510 scopus 로고    scopus 로고
    • Nuclear reorganisation and chromatin decondensation are conserved, but distinct, mechanisms linked to Hox gene activation
    • Morey C, Da Silva NR, Perry P, Bickmore WA. Nuclear reorganisation and chromatin decondensation are conserved, but distinct, mechanisms linked to Hox gene activation. Development. 2007;134:909-19.
    • (2007) Development , vol.134 , pp. 909-919
    • Morey, C.1    Silva, N.R.2    Perry, P.3    Bickmore, W.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.