메뉴 건너뛰기




Volumn 36, Issue 4, 2016, Pages 299-304

Pharmacogenetic tests in psychiatry

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; CYTOCHROME P450; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; RISPERIDONE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 84973299592     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0000000000000522     Document Type: Review
Times cited : (29)

References (60)
  • 1
    • 84924423679 scopus 로고    scopus 로고
    • Some thoughts about medical caring
    • Shader RI. Some thoughts about medical caring. J Clin Psychopharmacol. 2015; 35: 115-116.
    • (2015) J Clin Psychopharmacol , vol.35 , pp. 115-116
    • Shader, R.I.1
  • 2
    • 84857852960 scopus 로고    scopus 로고
    • Evidence-based medicine versus personalized medicine: Are they enemies?
    • de Leon J. Evidence-based medicine versus personalized medicine: are they enemies?. J Clin Psychopharmacol. 2012; 32: 153-164.
    • (2012) J Clin Psychopharmacol , vol.32 , pp. 153-164
    • De Leon, J.1
  • 3
    • 0030822569 scopus 로고    scopus 로고
    • Massively parallel genomics
    • Fodor SP. Massively parallel genomics. Science. 1997; 277: 393-395.
    • (1997) Science , vol.277 , pp. 393-395
    • Fodor, S.P.1
  • 4
    • 13844289378 scopus 로고    scopus 로고
    • Genes arrayed out for you: The amazing world of microarrays
    • Chaudhuri JD. Genes arrayed out for you: the amazing world of microarrays. Med Sci Monit. 2005; 11: RA52-RA62.
    • (2005) Med Sci Monit , vol.11 , pp. RA52-RA62
    • Chaudhuri, J.D.1
  • 5
    • 0031460022 scopus 로고    scopus 로고
    • New research horizons
    • Science
    • Science. New research horizons. Science. 1997; 278: 2039.
    • (1997) Science , vol.278 , pp. 2039
  • 6
    • 0032804249 scopus 로고    scopus 로고
    • Performance of the affymetrix genechip HIV prt 440 platform for antiretroviral drug resistance genotyping of human immunodeficiency virus type 1 clades and viral isolates with length polymorphisms
    • Vahey M, Nau ME, Barrick S, et al. Performance of the Affymetrix GeneChip HIV PRT 440 platform for antiretroviral drug resistance genotyping of human immunodeficiency virus type 1 clades and viral isolates with length polymorphisms. J ClinMicrobiol. 1999; 37: 2533-2537.
    • (1999) J ClinMicrobiol , vol.37 , pp. 2533-2537
    • Vahey, M.1    Nau, M.E.2    Barrick, S.3
  • 7
    • 0032730108 scopus 로고    scopus 로고
    • Double-blind study of clozapine dose response in chronic schizophrenia
    • Simpson GM, Josiassen RC, Stanilla JK, et al. Double-blind study of clozapine dose response in chronic schizophrenia. Am J Psychiatry. 1999; 156: 1744-1750.
    • (1999) Am J Psychiatry , vol.156 , pp. 1744-1750
    • Simpson, G.M.1    Josiassen, R.C.2    Stanilla, J.K.3
  • 8
    • 0027985726 scopus 로고
    • Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test
    • Bertilsson L, Carrillo JA, Dahl ML, et al. Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. Br J Clin Pharmacol. 1994; 38: 471-473.
    • (1994) Br J Clin Pharmacol , vol.38 , pp. 471-473
    • Bertilsson, L.1    Carrillo, J.A.2    Dahl, M.L.3
  • 10
    • 10544248170 scopus 로고    scopus 로고
    • The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: Screening costs and influence on clinical outcomes in psychiatry
    • Chen S, Chou WH, Blouin RA, et al. The cytochrome P450 2D6 (CYP2D6) enzyme polymorphism: screening costs and influence on clinical outcomes in psychiatry. Clin Pharmacol Ther. 1996; 60: 522-534.
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 522-534
    • Chen, S.1    Chou, W.H.2    Blouin, R.A.3
  • 11
    • 0031695414 scopus 로고    scopus 로고
    • Pilot study of the cytochrome P450-2D6 genotype in a psychiatric state hospital
    • de Leon J, Barnhill J, Rogers T, et al. Pilot study of the cytochrome P450-2D6 genotype in a psychiatric state hospital. Am J Psychiatry. 1998; 155: 1278-1280.
    • (1998) Am J Psychiatry , vol.155 , pp. 1278-1280
    • De Leon, J.1    Barnhill, J.2    Rogers, T.3
  • 12
    • 0027436269 scopus 로고
    • Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects
    • Huang ML, Van Peer A, Woestenborghs R, et al. Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects. Clin Pharmacol Ther. 1993; 54: 257-268.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 257-268
    • Huang, M.L.1    Van Peer, A.2    Woestenborghs, R.3
  • 13
    • 0032776927 scopus 로고    scopus 로고
    • A pilot study on risperidone metabolism: The role of cytochromes P450 2D6 and 3A
    • Bork JA, Rogers T, Wedlund PJ, et al. A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A. J Clin Psychiatry. 1999; 60: 469-476.
    • (1999) J Clin Psychiatry , vol.60 , pp. 469-476
    • Bork, J.A.1    Rogers, T.2    Wedlund, P.J.3
  • 14
    • 0001697297 scopus 로고    scopus 로고
    • Extension of a pilot study: Impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness
    • Chou WH, Yan FX, de Leon J, et al. Extension of a pilot study: impact from the cytochrome P450 2D6 polymorphism on outcome and costs associated with severe mental illness. J Clin Psychopharmacol. 2000; 20: 246-251.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 246-251
    • Chou, W.H.1    Yan, F.X.2    De Leon, J.3
  • 15
    • 13844320650 scopus 로고    scopus 로고
    • The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation
    • de Leon J, Susce MT, Pan RM, et al. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation. J Clin Psychiatry. 2005; 66: 15-27.
    • (2005) J Clin Psychiatry , vol.66 , pp. 15-27
    • De Leon, J.1    Susce, M.T.2    Pan, R.M.3
  • 16
    • 34248597277 scopus 로고    scopus 로고
    • A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels
    • de Leon J, Susce MT, Pan RM, et al. A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels. Pharmacopsychiatry. 2007; 40: 93-102.
    • (2007) Pharmacopsychiatry , vol.40 , pp. 93-102
    • De Leon, J.1    Susce, M.T.2    Pan, R.M.3
  • 17
    • 84941042620 scopus 로고    scopus 로고
    • Addressing phenoconversion: The Achilles' heel of personalized medicine
    • Shah RR, Smith RL. Addressing phenoconversion: the Achilles' heel of personalized medicine. Br J Clin Pharmacol. 2015; 79: 222-240.
    • (2015) Br J Clin Pharmacol , vol.79 , pp. 222-240
    • Shah, R.R.1    Smith, R.L.2
  • 18
    • 84942549635 scopus 로고    scopus 로고
    • Phenoconversion and therapeutic drug monitoring
    • de Leon J. Phenoconversion and therapeutic drug monitoring. Br J Clin Pharmacol. 2015; 80: 777-778.
    • (2015) Br J Clin Pharmacol , vol.80 , pp. 777-778
    • De Leon, J.1
  • 20
    • 0036399255 scopus 로고    scopus 로고
    • Overview of biomarkers and surrogate endpoints in drug development
    • Wagner JA. Overview of biomarkers and surrogate endpoints in drug development. Dis Markers. 2002; 18: 41-46.
    • (2002) Dis Markers , vol.18 , pp. 41-46
    • Wagner, J.A.1
  • 21
    • 84927155719 scopus 로고    scopus 로고
    • Is psychiatry only neurology? or only abnormal psychology?. Déjà vu after 100 years
    • de Leon J. Is psychiatry only neurology?. Or only abnormal psychology?. Déjà vu after 100 years. Acta Neuropsychiatr. 2015; 27: 69-81.
    • (2015) Acta Neuropsychiatr , vol.27 , pp. 69-81
    • De Leon, J.1
  • 22
    • 84893501160 scopus 로고    scopus 로고
    • One hundred years of limited impact of jaspers' general psychopathology on us psychiatry
    • de Leon J. One hundred years of limited impact of Jaspers' General Psychopathology on US psychiatry. J NervMent Dis. 2014; 202: 79-87.
    • (2014) J NervMent Dis , vol.202 , pp. 79-87
    • De Leon, J.1
  • 23
    • 29544447266 scopus 로고    scopus 로고
    • The AmpliChip CYP450 genotyping test: Integrating a new clinical tool
    • de Leon J, Susce MT, Murray-Carmichael E. The AmpliChip CYP450 genotyping test: integrating a new clinical tool. Mol Diagn Ther. 2006; 10: 135-151.
    • (2006) Mol Diagn Ther , vol.10 , pp. 135-151
    • De Leon, J.1    Susce, M.T.2    Murray-Carmichael, E.3
  • 24
    • 85046914149 scopus 로고    scopus 로고
    • Pharmacogenomics: The implementation phase
    • SadeeW. Pharmacogenomics: the implementation phase. AAPS PharmSci. 2002; 4: E5.
    • (2002) AAPS PharmSci , vol.4 , pp. E5
    • Sadee, W.1
  • 25
  • 26
    • 57649139354 scopus 로고    scopus 로고
    • Pharmacogenomics: The promise of personalized medicine for CNS disorders
    • de Leon J. Pharmacogenomics: the promise of personalized medicine for CNS disorders. Neuropsychopharmacology. 2009; 34: 159-172.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 159-172
    • De Leon, J.1
  • 27
    • 33745944880 scopus 로고    scopus 로고
    • AmpliChip CYP450 test: Personalized medicine has arrived in psychiatry
    • de Leon J. AmpliChip CYP450 test: personalized medicine has arrived in psychiatry. Expert Rev Mol Diagn. 2006; 6: 277-286.
    • (2006) Expert Rev Mol Diagn , vol.6 , pp. 277-286
    • De Leon, J.1
  • 28
    • 57149135263 scopus 로고    scopus 로고
    • Pharmacogenetic testing in psychiatry: A review of features and clinical realities
    • de Leon J, Arranz MJ, Ruaño G. Pharmacogenetic testing in psychiatry: a review of features and clinical realities. Clin Lab Med. 2008; 28: 599-617.
    • (2008) Clin Lab Med , vol.28 , pp. 599-617
    • De Leon, J.1    Arranz, M.J.2    Ruaño, G.3
  • 29
    • 33845439872 scopus 로고    scopus 로고
    • Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays
    • Melis R, Lyon E, McMillin GA. Determination of CYP2D6, CYP2C9 and CYP2C19 genotypes with Tag-It mutation detection assays. Expert Rev Mol Diagn. 2006; 6: 811-820.
    • (2006) Expert Rev Mol Diagn , vol.6 , pp. 811-820
    • Melis, R.1    Lyon, E.2    McMillin, G.A.3
  • 30
    • 84959208572 scopus 로고    scopus 로고
    • Practical interpretation of CYP2D6 haplotypes: Comparison and integration of automated and expert calling
    • Ruaño G, Kocherla M, Graydon JS, et al. Practical interpretation of CYP2D6 haplotypes: comparison and integration of automated and expert calling. Clin Chim Acta. 2016; 456: 7-14.
    • (2016) Clin Chim Acta , vol.456 , pp. 7-14
    • Ruaño, G.1    Kocherla, M.2    Graydon, J.S.3
  • 31
    • 84898047653 scopus 로고    scopus 로고
    • Pharmacogenomic testing for neuropsychiatric drugs: Current status of drug labeling, guidelines for using genetic information and test options
    • Drozda K, Müller DJ, Bishop JR. Pharmacogenomic testing for neuropsychiatric drugs: current status of drug labeling, guidelines for using genetic information and test options. Pharmacotherapy. 2014; 34: 166-184.
    • (2014) Pharmacotherapy , vol.34 , pp. 166-184
    • Drozda, K.1    Müller, D.J.2    Bishop, J.R.3
  • 32
    • 84894473210 scopus 로고    scopus 로고
    • Pharmacogenomics in psychiatry: From therapeutic drug monitoring to genomic medicine
    • Crettol S, de Leon J, Hiemke C, et al. Pharmacogenomics in psychiatry: from therapeutic drug monitoring to genomic medicine. Clin Pharmacol Ther. 2014; 95: 254-257.
    • (2014) Clin Pharmacol Ther , vol.95 , pp. 254-257
    • Crettol, S.1    De Leon, J.2    Hiemke, C.3
  • 33
    • 30344457586 scopus 로고    scopus 로고
    • A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
    • Sim SC, Risinger C, Dahl ML, et al. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther. 2006; 79: 103-113.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 103-113
    • Sim, S.C.1    Risinger, C.2    Dahl, M.L.3
  • 34
    • 62449286261 scopus 로고    scopus 로고
    • DNA microarray technology in the clinical environment: The amplichip cyp450 test for cyp2d6 and cyp2c19 genotyping
    • de Leon J, Susce MT, Johnson M, et al. DNA microarray technology in the clinical environment: the AmpliChip CYP450 test for CYP2D6 and CYP2C19 genotyping. CNS Spectr. 2009; 14: 19-34.
    • (2009) CNS Spectr , vol.14 , pp. 19-34
    • De Leon, J.1    Susce, M.T.2    Johnson, M.3
  • 35
    • 31044442759 scopus 로고    scopus 로고
    • Pharmacogenetics in drug regulation: Promise, potential and pitfalls
    • Shah RR. Pharmacogenetics in drug regulation: promise, potential and pitfalls. Philos Trans R Soc Lond B Biol Sci. 2005; 360: 1617-1638.
    • (2005) Philos Trans R Soc Lond B Biol Sci , vol.360 , pp. 1617-1638
    • Shah, R.R.1
  • 36
    • 84978066281 scopus 로고    scopus 로고
    • The Secretary's Advisory Committee on Genetics Health and Society (SACGHS Available at Accessed May 21, 2016
    • The Secretary's Advisory Committee on Genetics, Health and Society (SACGHS). Coverage and Reimbursement of Genetic Tests and Services February 2006. Available at: http://osp.od.nih.gov/office-clinical-researchand-bioethics-policy/genetics-health-And-society/sacghs-Archives/.documents. Accessed May 21, 2016.
    • Coverage and Reimbursement of Genetic Tests and Services February 2006
  • 37
    • 84959559740 scopus 로고    scopus 로고
    • What is needed to incorporate clinical pharmacogenetic tests into the practice of psychopharmacotherapy?
    • de Leon J, Spina E.What is needed to incorporate clinical pharmacogenetic tests into the practice of psychopharmacotherapy?. Expert Rev Clin Pharmacol. 2016; 9: 351-354.
    • (2016) Expert Rev Clin Pharmacol , vol.9 , pp. 351-354
    • De Leon, J.1    Spina, E.2
  • 38
    • 84927574016 scopus 로고    scopus 로고
    • Focusing on drug versus disease mechanisms and on clinical subgrouping to advance personalised medicine in psychiatry
    • de Leon J. Focusing on drug versus disease mechanisms and on clinical subgrouping to advance personalised medicine in psychiatry. Acta Neuropsychiatr. 2014; 26: 327-333.
    • (2014) Acta Neuropsychiatr , vol.26 , pp. 327-333
    • De Leon, J.1
  • 39
    • 84895822855 scopus 로고    scopus 로고
    • Serotonin transporter gene (5-HTTLPR) polymorphism and efficacy of selective serotonin reuptake inhibitors-do we have sufficient evidence for clinical practice
    • Karlović D, Karlović D. Serotonin transporter gene (5-HTTLPR) polymorphism and efficacy of selective serotonin reuptake inhibitors-do we have sufficient evidence for clinical practice. Acta Clin Croat. 2013; 52: 353-362.
    • (2013) Acta Clin Croat , vol.52 , pp. 353-362
    • Karlović, D.1    Karlović, D.2
  • 40
    • 84857236103 scopus 로고    scopus 로고
    • Meta-Analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • Porcelli S, Fabbri C, Serretti A.Meta-Analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy. Eur Neuropsychopharmacol. 2012 22 239-258.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 42
    • 30044439732 scopus 로고    scopus 로고
    • Effect of a triallelic functional polymorphism of the serotonin-Transporter-linked promoter region on expression of serotonin transporter in the human brain
    • Parsey RV, Hastings RS, Oquendo MA, et al. Effect of a triallelic functional polymorphism of the serotonin-Transporter-linked promoter region on expression of serotonin transporter in the human brain. Am J Psychiatry. 2006; 163: 48-51.
    • (2006) Am J Psychiatry , vol.163 , pp. 48-51
    • Parsey, R.V.1    Hastings, R.S.2    Oquendo, M.A.3
  • 43
    • 84897894099 scopus 로고    scopus 로고
    • Pharmacogenomics in psychiatry: The relevance of receptor and transporter polymorphisms
    • Reynolds GP, McGowan OO, Dalton CF. Pharmacogenomics in psychiatry: the relevance of receptor and transporter polymorphisms. Br J Clin Pharmacol. 2014; 77: 654-672.
    • (2014) Br J Clin Pharmacol , vol.77 , pp. 654-672
    • Reynolds, G.P.1    McGowan, O.O.2    Dalton, C.F.3
  • 44
    • 79955463893 scopus 로고    scopus 로고
    • Pharmacogenetics: From bench to byte-An update of guidelines
    • Swen JJ, Nijenhuis M, de Boer A, et al. Pharmacogenetics: from bench to byte-An update of guidelines. Clin Pharmacol Ther. 2011; 89: 662-673.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 662-673
    • Swen, J.J.1    Nijenhuis, M.2    De Boer, A.3
  • 45
    • 84876665512 scopus 로고    scopus 로고
    • Clinical pharmacogenetics implementation consortium guideline for cyp2d6 and cyp2c19 genotypes and dosing of tricyclic antidepressants
    • Hicks JK, Swen JJ, Thorn CF, et al. Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants. Clin Pharmacol Ther. 2013; 93: 402-408.
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 402-408
    • Hicks, J.K.1    Swen, J.J.2    Thorn, C.F.3
  • 46
    • 84962294272 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 and CYP2C19 genotypes and dosing of selective serotonin reuptake inhibitors
    • Hicks JK, Bishop JR, Sangkuhl K, et al. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 and CYP2C19 genotypes and dosing of selective serotonin reuptake inhibitors. Clin Pharmacol Ther. 2015; 98: 127-134.
    • (2015) Clin Pharmacol Ther , vol.98 , pp. 127-134
    • Hicks, J.K.1    Bishop, J.R.2    Sangkuhl, K.3
  • 47
    • 84866479743 scopus 로고    scopus 로고
    • CYP2D6 genotype information to guide pimozide treatment in adult and pediatric patients: Basis for the US Food and Drug Administration's new dosing recommendations
    • Rogers HL, Bhattaram A, Zineh I, et al. CYP2D6 genotype information to guide pimozide treatment in adult and pediatric patients: basis for the U.S. Food and Drug Administration's new dosing recommendations. J Clin Psychiatry. 2012; 73: 1187-1190.
    • (2012) J Clin Psychiatry , vol.73 , pp. 1187-1190
    • Rogers, H.L.1    Bhattaram, A.2    Zineh, I.3
  • 48
    • 68449088877 scopus 로고    scopus 로고
    • ABCB1 and cytochrome P450 polymorphisms: Clinical pharmacogenetics of clozapine
    • Jaquenoud Sirot E, Knezevic B, Morena GP, et al. ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine. J Clin Psychopharmacol. 2009; 29: 319-326.
    • (2009) J Clin Psychopharmacol , vol.29 , pp. 319-326
    • Jaquenoud Sirot, E.1    Knezevic, B.2    Morena, G.P.3
  • 49
    • 84879563161 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: Implications for personalized medicine
    • Preskorn SH, Kane CP, Lobello K, et al. Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: implications for personalized medicine. J Clin Psychiatry. 2013; 74: 614-621.
    • (2013) J Clin Psychiatry , vol.74 , pp. 614-621
    • Preskorn, S.H.1    Kane, C.P.2    Lobello, K.3
  • 50
    • 84931059701 scopus 로고    scopus 로고
    • Translating pharmacogenetics to clinical practice: Do cytochrome P450 2D6 ultrarapid metabolizers need higher atomoxetine doses?
    • de Leon J. Translating pharmacogenetics to clinical practice: do cytochrome P450 2D6 ultrarapid metabolizers need higher atomoxetine doses?. J Am Acad Child Adolesc Psychiatry. 2015; 54: 532-534.
    • (2015) J Am Acad Child Adolesc Psychiatry , vol.54 , pp. 532-534
    • De Leon, J.1
  • 51
    • 84929032233 scopus 로고    scopus 로고
    • Clinical applications of CYP genotyping in psychiatry
    • Spina E, de Leon J. Clinical applications of CYP genotyping in psychiatry. J Neural Transm (Vienna). 2015; 122: 5-28.
    • (2015) J Neural Transm (Vienna , vol.122 , pp. 5-28
    • Spina, E.1    De Leon, J.2
  • 52
    • 1842784823 scopus 로고    scopus 로고
    • Medical genetics: A marker for Stevens-Johnson syndrome
    • Chung WH, Hung SI, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature. 2004; 428: 486.
    • (2004) Nature , vol.428 , pp. 486
    • Chung, W.H.1    Hung, S.I.2    Hong, H.S.3
  • 53
    • 79953216429 scopus 로고    scopus 로고
    • Carbamazepine-induced toxic effects and HLA-B 1502 screening in Taiwan
    • Chen P, Lin JJ, Lu CS, et al. Carbamazepine-induced toxic effects and HLA-B 1502 screening in Taiwan. N Engl J Med. 2011; 364: 1126-1133.
    • (2011) N Engl J Med , vol.364 , pp. 1126-1133
    • Chen, P.1    Lin, J.J.2    Lu, C.S.3
  • 54
    • 84952774045 scopus 로고    scopus 로고
    • FDA regulation of LDTs-An update
    • Jones PM. FDA regulation of LDTs-An update. MLO Med Lab Obs. 2015; 47: 18-19.
    • (2015) MLO Med Lab Obs , vol.47 , pp. 18-19
    • Jones, P.M.1
  • 55
    • 84959165252 scopus 로고    scopus 로고
    • Clinically significant pharmacokinetic drug interactions of antiepileptics drugs with new antidepressants and new antipsychotics
    • Spina E, Pisani F, de Leon J. Clinically significant pharmacokinetic drug interactions of antiepileptics drugs with new antidepressants and new antipsychotics. Pharmacol Res. 2016; 106: 72-86.
    • (2016) Pharmacol Res , vol.106 , pp. 72-86
    • Spina, E.1    Pisani, F.2    De Leon, J.3
  • 56
    • 84907423727 scopus 로고    scopus 로고
    • Paradoxes of US psychopharmacology practice in 2013: Undertreatment of severe mental illness and overtreatment of minor psychiatric problems
    • de Leon J. Paradoxes of US psychopharmacology practice in 2013: undertreatment of severe mental illness and overtreatment of minor psychiatric problems. J Clin Psychopharmacol. 2014; 34: 545-548.
    • (2014) J Clin Psychopharmacol , vol.34 , pp. 545-548
    • De Leon, J.1
  • 57
    • 84952981712 scopus 로고    scopus 로고
    • Antidepressants: Conundrums and complexities of efficacy studies
    • Pies RW. Antidepressants: conundrums and complexities of efficacy studies. J Clin Psychopharmacol. 2016; 36: 1-4.
    • (2016) J Clin Psychopharmacol , vol.36 , pp. 1-4
    • Pies, R.W.1
  • 58
    • 84957436286 scopus 로고    scopus 로고
    • Meta-Analyses with industry involvement are massively published and report no caveats for antidepressants
    • Ebrahim S, Bance S, Athale A, et al. Meta-Analyses with industry involvement are massively published and report no caveats for antidepressants. J Clin Epidemiol. 2016; 70: 155-163.
    • (2016) J Clin Epidemiol , vol.70 , pp. 155-163
    • Ebrahim, S.1    Bance, S.2    Athale, A.3
  • 59
    • 84871909017 scopus 로고    scopus 로고
    • Psychiatry, the pharmaceutical industry, and the road to better therapeutics
    • Fibiger HC. Psychiatry, the pharmaceutical industry, and the road to better therapeutics. Schizophr Bull. 2012; 38: 649-650.
    • (2012) Schizophr Bull , vol.38 , pp. 649-650
    • Fibiger, H.C.1
  • 60
    • 80052511566 scopus 로고    scopus 로고
    • Central nervous system drug development, basic, and clinical research thinking outside the box
    • Klein DF, Glick ID, Shader RI. Central nervous system drug development, basic, and clinical research thinking outside the box. J Clin Psychopharmacol. 2011; 31: 553-554.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 553-554
    • Klein, D.F.1    Glick, I.D.2    Shader, R.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.