Rational design of a carrier protein for the production of recombinant toxic peptides in Escherichia coli

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Pane, Katia ^a   Durante, Lorenzo ^a   Pizzo, Elio ^a   Varcamonti, Mario ^a   Zanfardino, Anna ^a   Sgambati, Valeria ^a   Di Maro, Antimo ^b   Carpentieri, Andrea ^a   Izzo, Viviana ^c   Di Donato, Alberto ^a   Cafaro, Valeria ^a   Notomista, Eugenio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; AMPICILLIN; ANTIINFECTIVE AGENT; ANTIMICROBIAL PEPTIDE GKY20; CARRIER PROTEIN; COLISTIN; CYSTEINE; DRUG CARRIER; METHIONINE; ONCONASE DCLESS H6; ONCONASE PEPTIDE GKY20 FUSION PROTEIN; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE; RANPIRNASE; RECOMBINANT PROTEIN; THROMBIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIMICROBIAL CATIONIC PEPTIDE; RIBONUCLEASE;

ACID CLEAVAGE; AMINO TERMINAL SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPARAGYL GLYCYL SEQUENCE; ASPARTYL PROLYL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG PURIFICATION; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; EXPRESSION VECTOR; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; NONHUMAN; PEPTIDE SYNTHESIS; PH; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SOLUBILITY; STRUCTURE ACTIVITY RELATION; GENETICS; HUMAN; METABOLISM;

ANTIMICROBIAL CATIONIC PEPTIDES; CARRIER PROTEINS; ESCHERICHIA COLI; HUMANS; RECOMBINANT PROTEINS; RIBONUCLEASES;

EID: 84973296281     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0146552     Document Type: Article

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