Human thrombin-derived host defense peptides inhibit neutrophil recruitment and tissue injury in severe acute pancreatitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 307, Issue 9, 2014, Pages G914-G921

  Merza, Mohammed ^a   Rahman, Milladur ^a   Zhang, Songen ^a   Hwaiz, Rundk ^a   Regner, Sara ^a   Schmidtchen, Artur ^a,b   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY   (Sweden)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Amylase; Chemokines; Inflammation; Leukocytes; Pancreas

Indexed keywords

AMYLASE; ANTIINFLAMMATORY AGENT; ARGININE; CXCL2 CHEMOKINE; GKY20 PEPTIDE; GKY25 PEPTIDE; HISTONE H3; HISTONE H4; INTERLEUKIN 6; MYELOPEROXIDASE; PEPTIDE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG; WFF25 PEPTIDE; CD11B ANTIGEN; CXCL2 PROTEIN, MOUSE; HISTONE; PEPTIDE FRAGMENT; PEROXIDASE; THROMBIN;

ACUTE PANCREATITIS; AMYLASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLEEDING; BLOOD LEVEL; CHEMOTAXIS; CONTROLLED STUDY; DRUG PROTEIN BINDING; EDEMA; IN VITRO STUDY; MOUSE; NECROSIS; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; TISSUE INJURY; AMINO ACID SEQUENCE; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGY; MALE; METABOLISM; MOLECULAR GENETICS; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PATHOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CHEMOKINE CXCL2; HISTONES; HUMANS; INTERLEUKIN-6; MACROPHAGE-1 ANTIGEN; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NEUTROPHIL INFILTRATION; NEUTROPHILS; PANCREAS; PANCREATITIS, ACUTE NECROTIZING; PEPTIDE FRAGMENTS; PEROXIDASE; THROMBIN;

EID: 84908360947     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00237.2014     Document Type: Article

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