TLR4 deficiency impairs oligodendrocyte formation in the injured spinal cord

Journal of Neuroscience

Volumn 36, Issue 23, 2016, Pages 6352-6364

  Church, Jamie S ^a   Kigerl, Kristina A ^a   Lerch, Jessica K ^a   Popovich, Phillip G ^a   McTigue, Dana M ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Growth factor; Inflammation; Macrophage; Microglia; Myelin; Phagocytosis

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; FERRITIN; FIBROBLAST GROWTH FACTOR 2; INHIBITOR OF DIFFERENTIATION 4; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; MESSENGER RNA; MYELIN; NEURON GLIAL ANTIGEN 2; PLATELET DERIVED GROWTH FACTOR A; SOMATOMEDIN B; SOMATOMEDIN C; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; TLR4 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRDU ASSAY; CELL LOSS; CONTROLLED STUDY; GENOTYPE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; IRON STORAGE; LOCOMOTION; MALE; MOUSE; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; RNA ISOLATION; SPINAL CORD INJURY; TUNEL ASSAY; ANIMAL; AXON; C3H MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONVALESCENCE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GENETICS; MACROPHAGE; METABOLISM; NERVE REGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; AXONS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; MACROPHAGES; MALE; MICE; MICE, INBRED C3H; MICE, TRANSGENIC; NERVE REGENERATION; OLIGODENDROGLIA; PHAGOCYTOSIS; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; TOLL-LIKE RECEPTOR 4;

EID: 84973277692     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0353-16.2016     Document Type: Article

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