Toll-like receptor 4 deficiency impairs microglial phagocytosis of degenerating axons

GLIA

Volumn 62, Issue 12, 2014, Pages 1982-1991

  Rajbhandari, Labchan ^a   Tegenge, Million Adane ^a   Shrestha, Shiva ^a   Ganesh Kumar, Nishant ^a   Malik, Adeel ^a   Mithal, Aditya ^a   Hosmane, Suneil ^a   Venkatesan, Arun ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Axon degeneration; Microglia; Multiple sclerosis; Phagocytosis; Regeneration

Indexed keywords

INTERFERON; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; PURINERGIC P2X7 RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CD11B ANTIGEN; CYTOKINE; ETHYL 6-(N-(2-CHLORO-4-FLUOROPHENYL)SULFAMOYL)CYCLOHEX-1-ENE-1-CARBOXYLATE; SULFONAMIDE; TLR4 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MICROGLIA; MOUSE; NERVE FIBER; NERVE FIBER DEGENERATION; NERVE FIBER TRANSECTION; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT; WALLERIAN DEGENERATION; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; COCULTURE; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; METABOLISM; MICROFLUIDIC ANALYSIS; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, CD11B; AXONS; CALCIUM-BINDING PROTEINS; COCULTURE TECHNIQUES; CYTOKINES; EMBRYO, MAMMALIAN; HIPPOCAMPUS; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROGLIA; NERVE DEGENERATION; NEURONS; PHAGOCYTOSIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2X7; SIGNAL TRANSDUCTION; SULFONAMIDES; TOLL-LIKE RECEPTOR 4;

EID: 84924115599     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22719     Document Type: Article

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