-
1
-
-
84927172971
-
2014 FDA drug approvals
-
A. Mullard 2014 FDA drug approvals Nat. Rev. Drug Discov. 14 2015 77 81
-
(2015)
Nat. Rev. Drug Discov.
, vol.14
, pp. 77-81
-
-
Mullard, A.1
-
2
-
-
84934999252
-
2014 prescription medications in the United States: Tremendous growth, specialty/orphan drug expansion, and dispensed prescriptions continue to increase
-
C.W. Lindsley 2014 prescription medications in the United States: tremendous growth, specialty/orphan drug expansion, and dispensed prescriptions continue to increase ACS Chem. Neurosci. 6 2015 811 812
-
(2015)
ACS Chem. Neurosci.
, vol.6
, pp. 811-812
-
-
Lindsley, C.W.1
-
3
-
-
0030154874
-
Sildenafil: An orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction
-
M. Boolell, and et al. Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction Int. J. Impot. Res. 8 1996 47 52
-
(1996)
Int. J. Impot. Res.
, vol.8
, pp. 47-52
-
-
Boolell, M.1
-
4
-
-
34248598317
-
Inhibition of angiogenesis by the antifungal drug itraconazole
-
C.R. Chong, and et al. Inhibition of angiogenesis by the antifungal drug itraconazole ACS Chem. Biol. 2 2007 263 270
-
(2007)
ACS Chem. Biol.
, vol.2
, pp. 263-270
-
-
Chong, C.R.1
-
5
-
-
84876411054
-
Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer
-
C.M. Rudin, and et al. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer J. Thorac. Oncol. 8 2013 619 623
-
(2013)
J. Thorac. Oncol.
, vol.8
, pp. 619-623
-
-
Rudin, C.M.1
-
6
-
-
84927614039
-
A Phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease
-
H.B. Nygaard, and et al. A Phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer's disease Alzheimers Res. Ther. 7 2015 35
-
(2015)
Alzheimers Res. Ther.
, vol.7
, pp. 35
-
-
Nygaard, H.B.1
-
7
-
-
84930042702
-
Fyn inhibition rescues established memory and synapse loss in Alzheimer mice
-
A.C. Kaufman, and et al. Fyn inhibition rescues established memory and synapse loss in Alzheimer mice Annal. Neurol. 77 2015 953 971
-
(2015)
Annal. Neurol.
, vol.77
, pp. 953-971
-
-
Kaufman, A.C.1
-
8
-
-
84945366208
-
Essential medicines are still essential
-
A.L. Gray, and et al. Essential medicines are still essential Lancet 386 2015 1601 1603
-
(2015)
Lancet
, vol.386
, pp. 1601-1603
-
-
Gray, A.L.1
-
9
-
-
84886953565
-
Phenotypic screens as a renewed approach for drug discovery
-
W. Zheng, and et al. Phenotypic screens as a renewed approach for drug discovery Drug Discov. Today 18 2013 1067 1073
-
(2013)
Drug Discov. Today
, vol.18
, pp. 1067-1073
-
-
Zheng, W.1
-
11
-
-
84938059590
-
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling
-
A.M. Sandercock, and et al. Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling Mol. Cancer 14 2015 147
-
(2015)
Mol. Cancer
, vol.14
, pp. 147
-
-
Sandercock, A.M.1
-
12
-
-
84906754009
-
Chemical signatures and new drug targets for gametocytocidal drug development
-
W. Sun, and et al. Chemical signatures and new drug targets for gametocytocidal drug development Sci. Rep. 4 2014 3743
-
(2014)
Sci. Rep.
, vol.4
, pp. 3743
-
-
Sun, W.1
-
13
-
-
85056067711
-
High-throughput multiplexed quantitation of protein aggregation and cytotoxicity in a Huntington's disease model
-
S.A. Titus, and et al. High-throughput multiplexed quantitation of protein aggregation and cytotoxicity in a Huntington's disease model Curr. Chem. Genom. 6 2012 79 86
-
(2012)
Curr. Chem. Genom.
, vol.6
, pp. 79-86
-
-
Titus, S.A.1
-
14
-
-
77951879452
-
Human stem cells and drug screening: Opportunities and challenges
-
A.D. Ebert, and C.N. Svendsen Human stem cells and drug screening: opportunities and challenges Nat. Rev. Drug Discov. 9 2010 367 372
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 367-372
-
-
Ebert, A.D.1
Svendsen, C.N.2
-
15
-
-
84887878750
-
Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy
-
C. Carlson, and et al. Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy J. Biomol. Screen. 18 2013 1203 1211
-
(2013)
J. Biomol. Screen.
, vol.18
, pp. 1203-1211
-
-
Carlson, C.1
-
16
-
-
84898034713
-
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons
-
B.J. Wainger, and et al. Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons Cell Rep. 7 2014 1 11
-
(2014)
Cell Rep.
, vol.7
, pp. 1-11
-
-
Wainger, B.J.1
-
17
-
-
79961240592
-
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets
-
J. Yuan, and et al. Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets Science 333 2011 724 729
-
(2011)
Science
, vol.333
, pp. 724-729
-
-
Yuan, J.1
-
18
-
-
77649188974
-
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs
-
J. Mu, and et al. Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs Nat. Genet. 42 2010 268 271
-
(2010)
Nat. Genet.
, vol.42
, pp. 268-271
-
-
Mu, J.1
-
19
-
-
84884472431
-
Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs
-
M. Shen, and et al. Identification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugs PLoS One 8 2013 e75252
-
(2013)
PLoS One
, vol.8
, pp. e75252
-
-
Shen, M.1
-
20
-
-
84869223163
-
Delta-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders
-
M. Xu, and et al. delta-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders J. Biol. Chem. 287 2012 39349 39360
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 39349-39360
-
-
Xu, M.1
-
21
-
-
84924964870
-
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs
-
J. Kouznetsova, and et al. Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs Emerg. Microbes Infect. 3 2014 e84
-
(2014)
Emerg. Microbes Infect.
, vol.3
, pp. e84
-
-
Kouznetsova, J.1
-
22
-
-
33750339228
-
A network dysfunction perspective on neurodegenerative diseases
-
J.J. Palop, and et al. A network dysfunction perspective on neurodegenerative diseases Nature 443 2006 768 773
-
(2006)
Nature
, vol.443
, pp. 768-773
-
-
Palop, J.J.1
-
23
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
A.L. Barabasi, and et al. Network medicine: a network-based approach to human disease Nat. Rev. Genet. 12 2011 56 68
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 56-68
-
-
Barabasi, A.L.1
-
24
-
-
84877931785
-
Polypharmacology in a single drug: Multitarget drugs
-
M.L. Bolognesi Polypharmacology in a single drug: multitarget drugs Curr. Med. Chem. 20 2013 1639 1645
-
(2013)
Curr. Med. Chem.
, vol.20
, pp. 1639-1645
-
-
Bolognesi, M.L.1
-
25
-
-
84940029055
-
Computational polypharmacology comes of age
-
G. Rastelli, and L. Pinzi Computational polypharmacology comes of age Front. Pharmacol. 6 2015 157
-
(2015)
Front. Pharmacol.
, vol.6
, pp. 157
-
-
Rastelli, G.1
Pinzi, L.2
-
26
-
-
84888872073
-
A novel QSAR model of Salmonella mutagenicity and its application in the safety assessment of drug impurities
-
A. Valencia, and et al. A novel QSAR model of Salmonella mutagenicity and its application in the safety assessment of drug impurities Toxicol. Appl. Pharmacol. 273 2013 427 434
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.273
, pp. 427-434
-
-
Valencia, A.1
-
27
-
-
33749335282
-
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
-
J. Lamb, and et al. The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease Science 313 2006 1929 1935
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
-
28
-
-
84945272320
-
Relating chemical structure to cellular response: An integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds
-
B. Chen, and et al. Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11,000 compounds CPT Pharmacometrics Syst. Pharmacol. 4 2015 576 584
-
(2015)
CPT Pharmacometrics Syst. Pharmacol.
, vol.4
, pp. 576-584
-
-
Chen, B.1
-
29
-
-
84898653013
-
Multi-objective molecular de novo design by adaptive fragment prioritization
-
M. Reutlinger, and et al. Multi-objective molecular de novo design by adaptive fragment prioritization Angewandte Chemie 53 2014 4244 4248
-
(2014)
Angewandte Chemie
, vol.53
, pp. 4244-4248
-
-
Reutlinger, M.1
-
30
-
-
84921491980
-
Multidimensional de novo design reveals 5-HT2B receptor-selective ligands
-
T. Rodrigues, and et al. Multidimensional de novo design reveals 5-HT2B receptor-selective ligands Angew. Chem. 54 2015 1551 1555
-
(2015)
Angew. Chem.
, vol.54
, pp. 1551-1555
-
-
Rodrigues, T.1
-
31
-
-
84897548931
-
Exploiting polypharmacology for drug target deconvolution
-
T.S. Gujral, and et al. Exploiting polypharmacology for drug target deconvolution Proc. Natl. Acad. Sci. U. S. A. 111 2014 5048 5053
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 5048-5053
-
-
Gujral, T.S.1
-
32
-
-
84946045336
-
The RCSB Protein Data Bank: Views of structural biology for basic and applied research and education
-
P.W. Rose, and et al. The RCSB Protein Data Bank: views of structural biology for basic and applied research and education Nucleic Acids Res. 43 2015 D345 D356
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D345-D356
-
-
Rose, P.W.1
-
33
-
-
84937517878
-
The role of electronic healthcare record databases in paediatric drug safety surveillance: A retrospective cohort study
-
S. de Bie, and et al. The role of electronic healthcare record databases in paediatric drug safety surveillance: a retrospective cohort study Br. J. Clin. Pharmacol. 80 2015 304 314
-
(2015)
Br. J. Clin. Pharmacol.
, vol.80
, pp. 304-314
-
-
De Bie, S.1
-
34
-
-
84957882302
-
Combination therapies in oncology
-
R.M. Webster Combination therapies in oncology Nat. Rev. Drug Discov. 15 2016 81 82
-
(2016)
Nat. Rev. Drug Discov.
, vol.15
, pp. 81-82
-
-
Webster, R.M.1
-
35
-
-
59349083179
-
Mechanisms of drug combinations: Interaction and network perspectives
-
J. Jia, and et al. Mechanisms of drug combinations: interaction and network perspectives Nat. Rev. Drug Discov. 8 2009 111 128
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 111-128
-
-
Jia, J.1
-
36
-
-
75149130051
-
Targeting the cancer kinome through polypharmacology
-
Z.A. Knight, and et al. Targeting the cancer kinome through polypharmacology Nat. Rev. Cancer 10 2010 130 137
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 130-137
-
-
Knight, Z.A.1
-
37
-
-
84857090723
-
Phase i study of bosutinib, a Src/Abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors
-
A.I. Daud, and et al. Phase I study of bosutinib, a Src/Abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors Clin. Cancer Res. 18 2012 1092 1100
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 1092-1100
-
-
Daud, A.I.1
-
38
-
-
84946066788
-
Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo
-
Z. Yu, and et al. Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo Oncotarget 6 2015 32930 32943
-
(2015)
Oncotarget
, vol.6
, pp. 32930-32943
-
-
Yu, Z.1
-
39
-
-
84919443958
-
Patient-derived models of acquired resistance can identify effective drug combinations for cancer
-
A.S. Crystal, and et al. Patient-derived models of acquired resistance can identify effective drug combinations for cancer Science 346 2014 1480 1486
-
(2014)
Science
, vol.346
, pp. 1480-1486
-
-
Crystal, A.S.1
-
40
-
-
0029095483
-
Time to hit HIV, early and hard
-
D.D. Ho Time to hit HIV, early and hard N. Eng. J. Med. 333 1995 450 451
-
(1995)
N. Eng. J. Med.
, vol.333
, pp. 450-451
-
-
Ho, D.D.1
-
41
-
-
84929439166
-
A 4-drug combination (Viekira Pak) for hepatitis C
-
M. Abramowicz, and et al. A 4-drug combination (Viekira Pak) for hepatitis C JAMA 313 2015 1857 1858
-
(2015)
JAMA
, vol.313
, pp. 1857-1858
-
-
Abramowicz, M.1
-
42
-
-
84904892931
-
Spread of artemisinin resistance in Plasmodium falciparum malaria
-
E.A. Ashley, and et al. Spread of artemisinin resistance in Plasmodium falciparum malaria N. Eng. J. Med. 371 2014 411 423
-
(2014)
N. Eng. J. Med.
, vol.371
, pp. 411-423
-
-
Ashley, E.A.1
-
43
-
-
84942583278
-
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
-
B.T. Mott, and et al. High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations Sci. Rep. 5 2015 13891
-
(2015)
Sci. Rep.
, vol.5
, pp. 13891
-
-
Mott, B.T.1
-
44
-
-
84905487382
-
Synergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruzi
-
J.D. Planer, and et al. Synergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruzi PLoS Negl. Trop. Dis. 8 2014 e2977
-
(2014)
PLoS Negl. Trop. Dis.
, vol.8
, pp. e2977
-
-
Planer, J.D.1
-
45
-
-
84895780454
-
Miltefosine and polyhexamethylene biguanide: A new drug combination for the treatment of Acanthamoeba keratitis
-
Z.A. Polat, and et al. Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis Clin. Experiment. Ophthalmol. 42 2014 151 158
-
(2014)
Clin. Experiment. Ophthalmol.
, vol.42
, pp. 151-158
-
-
Polat, Z.A.1
-
46
-
-
79955551409
-
Successful treatment of adult onset Langerhans cell histiocytosis with multi-drug combination therapy
-
E. Matsuki, and et al. Successful treatment of adult onset Langerhans cell histiocytosis with multi-drug combination therapy Int. Med. 50 2011 909 914
-
(2011)
Int. Med.
, vol.50
, pp. 909-914
-
-
Matsuki, E.1
-
47
-
-
84979562049
-
An exploratory randomised double-blind and placebo-controlled Phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A
-
S. Attarian, and et al. An exploratory randomised double-blind and placebo-controlled Phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A Orphanet J. Rare Dis. 9 2014 199
-
(2014)
Orphanet J. Rare Dis.
, vol.9
, pp. 199
-
-
Attarian, S.1
-
48
-
-
84926343938
-
Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: A retrospective cohort study
-
M.D. Zilberberg, and et al. Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: a retrospective cohort study Crit. Care 18 2014 596
-
(2014)
Crit. Care
, vol.18
, pp. 596
-
-
Zilberberg, M.D.1
-
49
-
-
84872732888
-
Ceftazidime-avibactam: A novel cephalosporin/beta-lactamase inhibitor combination
-
G.G. Zhanel, and et al. Ceftazidime-avibactam: a novel cephalosporin/beta-lactamase inhibitor combination Drugs 73 2013 159 177
-
(2013)
Drugs
, vol.73
, pp. 159-177
-
-
Zhanel, G.G.1
-
50
-
-
19944434201
-
CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
-
Y. Jin, and et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment J. Natl. Cancer Inst. 97 2005 30 39
-
(2005)
J. Natl. Cancer Inst.
, vol.97
, pp. 30-39
-
-
Jin, Y.1
-
51
-
-
76649089656
-
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: A population based cohort study
-
C.M. Kelly, and et al. Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study BMJ 340 2010 c693
-
(2010)
BMJ
, vol.340
, pp. c693
-
-
Kelly, C.M.1
-
52
-
-
84885308430
-
Drug-drug interactions during antiviral therapy for chronic hepatitis C
-
J.J. Kiser, and et al. Drug-drug interactions during antiviral therapy for chronic hepatitis C Nat. Rev. Gastroenterol. Hepatol. 10 2013 596 606
-
(2013)
Nat. Rev. Gastroenterol. Hepatol.
, vol.10
, pp. 596-606
-
-
Kiser, J.J.1
-
53
-
-
80051920720
-
Second-wave protease inhibitors: Choosing an heir
-
S. Ciesek, and et al. Second-wave protease inhibitors: choosing an heir Clin. Liver Dis. 15 2011 597 609
-
(2011)
Clin. Liver Dis.
, vol.15
, pp. 597-609
-
-
Ciesek, S.1
-
54
-
-
15044349115
-
The efficiency of multi-target drugs: The network approach might help drug design
-
P. Csermely, and et al. The efficiency of multi-target drugs: the network approach might help drug design Trends Pharmacol. Sci. 26 2005 178 182
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 178-182
-
-
Csermely, P.1
-
55
-
-
33750546736
-
The trouble with making combination drugs
-
S. Frantz The trouble with making combination drugs Nat. Rev. Drug Discov. 5 2006 881 882
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 881-882
-
-
Frantz, S.1
-
56
-
-
84901357361
-
Toward better drug repositioning: Prioritizing and integrating existing methods into efficient pipelines
-
G.X. Jin, and S.T.C. Wong Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines Drug Discov. Today 19 2014 637 644
-
(2014)
Drug Discov. Today
, vol.19
, pp. 637-644
-
-
Jin, G.X.1
Wong, S.T.C.2
-
57
-
-
84961318149
-
Optimization of drug combinations using feedback system control
-
P. Nowak-Sliwinska, and et al. Optimization of drug combinations using feedback system control Nat. Protocols 11 2016 302 315
-
(2016)
Nat. Protocols
, vol.11
, pp. 302-315
-
-
Nowak-Sliwinska, P.1
-
58
-
-
84960392064
-
Updates on drug-target network; Facilitating polypharmacology and data integration by growth of DrugBank database
-
pii: bbv094
-
F. Barneh, and et al. Updates on drug-target network; facilitating polypharmacology and data integration by growth of DrugBank database Brief. Bioinf. 2015 pii: bbv094
-
(2015)
Brief. Bioinf.
-
-
Barneh, F.1
-
59
-
-
84866067701
-
Literature based drug interaction prediction with clinical assessment using electronic medical records: Novel myopathy associated drug interactions
-
J.D. Duke, and et al. Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions PLoS Comput. Biol. 8 2012 e1002614
-
(2012)
PLoS Comput. Biol.
, vol.8
, pp. e1002614
-
-
Duke, J.D.1
-
60
-
-
84948671877
-
A novel algorithm for analyzing drug-drug interactions from MEDLINE literature
-
Y. Lu, and et al. A novel algorithm for analyzing drug-drug interactions from MEDLINE literature Sci. Rep. 5 2015 17357
-
(2015)
Sci. Rep.
, vol.5
, pp. 17357
-
-
Lu, Y.1
-
61
-
-
84907027073
-
Similarity-based modeling in large-scale prediction of drug-drug interactions
-
S. Vilar, and et al. Similarity-based modeling in large-scale prediction of drug-drug interactions Nat. Protocols 9 2014 2147 2163
-
(2014)
Nat. Protocols
, vol.9
, pp. 2147-2163
-
-
Vilar, S.1
-
62
-
-
84862510972
-
Large-scale prediction and testing of drug activity on side-effect targets
-
E. Lounkine, and et al. Large-scale prediction and testing of drug activity on side-effect targets Nature 486 2012 361 367
-
(2012)
Nature
, vol.486
, pp. 361-367
-
-
Lounkine, E.1
-
63
-
-
84901502098
-
A randomized open-label study of 3-versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals
-
M. Markowitz, and et al. A randomized open-label study of 3-versus 5-drug combination antiretroviral therapy in newly HIV-1-infected individuals JAIDS 66 2014 140 147
-
(2014)
JAIDS
, vol.66
, pp. 140-147
-
-
Markowitz, M.1
-
64
-
-
33746381549
-
A clinical drug library screen identifies astemizole as an antimalarial agent
-
C.R. Chong, and et al. A clinical drug library screen identifies astemizole as an antimalarial agent Nat. Chem. Biol. 2 2006 415 416
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 415-416
-
-
Chong, C.R.1
-
65
-
-
79955428497
-
The NCGC pharmaceutical collection: A comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
-
R. Huang, and et al. The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics Sci. Transl. Med. 3 2011 80ps16
-
(2011)
Sci. Transl. Med.
, vol.3
, pp. 80ps16
-
-
Huang, R.1
-
66
-
-
33947280523
-
Lead-like, drug-like or Pub-like: How different are they?
-
T.I. Oprea, and et al. Lead-like, drug-like or Pub-like: how different are they? J. Comput. Aided Mol. Des. 21 2007 113 119
-
(2007)
J. Comput. Aided Mol. Des.
, vol.21
, pp. 113-119
-
-
Oprea, T.I.1
-
67
-
-
12944335007
-
Reversal of a full-length mutant Huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation
-
J. Wang, and et al. Reversal of a full-length mutant Huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation BMC Neurosci. 6 2005 1
-
(2005)
BMC Neurosci.
, vol.6
, pp. 1
-
-
Wang, J.1
|