Rifampin phosphotransferase is an unusual antibiotic resistance kinase

Nature Communications

Volumn 7, Issue , 2016, Pages

  Stogios, Peter J ^a   Cox, Georgina ^b   Spanogiannopoulos, Peter ^b   Pillon, Monica C ^c   Waglechner, Nicholas ^b   Skarina, Tatiana ^b   Koteva, Kalinka ^b   Guarné, Alba ^c   Savchenko, Alexei ^a   Wright, Gerard D ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; PHOSPHOTRANSFERASE; RIFAMPICIN; ADENOSINE TRIPHOSPHATE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; BACTERIUM; CATALYSIS; CHEMICAL BINDING; ENZYME ACTIVITY; MUTATION; REACTION KINETICS; SPATIAL DISTRIBUTION; X-RAY SPECTROSCOPY;

ANTIBIOTIC RESISTANCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME CONFORMATION; IN VITRO STUDY; LISTERIA MONOCYTOGENES; MUTAGENESIS; NONHUMAN; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; BINDING SITE; BIOTRANSFORMATION; CHEMISTRY; CLASSIFICATION; DRUG EFFECTS; ENZYMOLOGY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; PHYLOGENY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BINDING SITES; BIOTRANSFORMATION; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION; LISTERIA MONOCYTOGENES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOTRANSFERASES; PHYLOGENY; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RIFAMPIN; SEQUENCE ALIGNMENT;

EID: 84971669517     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11343     Document Type: Article

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