Pyruvate site of pyruvate phosphate dikinase: Crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis

Biochemistry

Volumn 41, Issue 3, 2002, Pages 780-787

  Herzberg, Osnat ^a   Chen, Celia C H ^a   Liu, Sijiu ^a   Tempczyk, Aleksandra ^a   Howard, Andrew ^b,c   Wei, Min ^d   Ye, Dongmei ^d   Dunaway Mariano, Debra ^d  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

^c ARGONNE NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUBSTRATE BINDING;

BIOCHEMISTRY; CATALYSIS; CRYSTAL STRUCTURE; MUTAGENS;

ENZYME KINETICS;

ADENOSINE TRIPHOSPHATE; MAGNESIUM ION; PYRUVATE KINASE; PYRUVATE PHOSPHATE DIKINASE; PYRUVIC ACID DERIVATIVE;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MUTATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; APOENZYMES; BINDING SITES; CLONING, MOLECULAR; CLOSTRIDIUM; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PYRUVATE, ORTHOPHOSPHATE DIKINASE; PYRUVIC ACID; RECOMBINANT PROTEINS;

EID: 0037154102     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi011799+     Document Type: Article

References (24)