SCOPUS 정보 검색 플랫폼

MedChemComm

Volumn 7, Issue 5, 2016, Pages 990-998

Synthesis and evaluation of donepezil-ferulic acid hybrids as multi-target-directed ligands against Alzheimer's disease

(7) Xu, Wei a Wang, Xiao Bing a Wang, Zhi Min a Wu, Jia Jia a Li, Fan a Wang, Jin a Kong, Ling Yi a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; CURCUMIN; DONEPEZIL; FERULIC ACID; LIGAND; TROLOX C;

ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING SITE; BLOOD BRAIN BARRIER; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC50; IN VITRO STUDY; MOLECULAR DOCKING; NEUROPROTECTION; PC12 CELL LINE; PRIORITY JOURNAL;

EID: 84971357218 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c6md00053c Document Type: Article

Times cited : (50)

References (49)

1
- 84941331228
- Alzheimer's Disease International, London
- M. Prince, A. Wimo, M. Guerchet, G.-C. Ali, Y.-T. Wu and M. Prina, World Alzheimer Report 2015, Alzheimer's Disease International, London, 2015
- (2015) World Alzheimer Report 2015
- Prince, M.¹ Wimo, A.² Guerchet, M.³ Ali, G.-C.⁴ Wu, Y.-T.⁵ Prina, M.⁶

2
- 0042020173
- E. Scarpini P. Scheltens H. Feldman Lancet Neurol. 2003 2 539 547
- (2003) Lancet Neurol. , vol.2 , pp. 539-547
- Scarpini, E.¹ Scheltens, P.² Feldman, H.³

3
- 84899495020
- Characterization of biometal profiles in neurological disorders
- S. Pfaender A. M. Grabrucker Characterization of biometal profiles in neurological disorders Metallomics 2014 6 960 977
- (2014) Metallomics , vol.6 , pp. 960-977
- Pfaender, S.¹ Grabrucker, A.M.²

4
- 67649678412
- V. P. Reddy X. Zhu G. Perry M. A. Smith J. Alzheimers Dis. 2009 16 763 774
- (2009) J. Alzheimers Dis. , vol.16 , pp. 763-774
- Reddy, V.P.¹ Zhu, X.² Perry, G.³ Smith, M.A.⁴

5
- 70349923038
- R. Jakob-Roetne H. Jacobsen Angew. Chem.; Int. Ed. 2009 48 3030 3059
- (2009) Angew. Chem.; Int. Ed. , vol.48 , pp. 3030-3059
- Jakob-Roetne, R.¹ Jacobsen, H.²

6
- 84862619683
- Winchester, England
- M. Bond, G. Rogers, J. Peters, R. Anderson, M. Hoyle, A. Miners, T. Moxham, S. Davis, P. Thokala, A. Wailoo, M. Jeffreys and C. Hyde, Health technology assessment, Winchester, England, 2012, vol. 16, pp. 1-470
- (2012) Health Technology Assessment , vol.16 , pp. 1-470
- Bond, M.¹ Rogers, G.² Peters, J.³ Anderson, R.⁴ Hoyle, M.⁵ Miners, A.⁶ Moxham, T.⁷ Davis, S.⁸ Thokala, P.⁹ Wailoo, A.¹⁰ Jeffreys, M.¹¹ Hyde, C.¹²

7
- 84896706419
- D. Wilkinson Y. Wirth C. Goebel Dementia Geriatr. Cognit. Disord. 2014 37 71 85
- (2014) Dementia Geriatr. Cognit. Disord. , vol.37 , pp. 71-85
- Wilkinson, D.¹ Wirth, Y.² Goebel, C.³

8
- 10044270820
- B. Schmitt T. Bernhardt H. J. Moeller I. Heuser L. Frolich CNS Drugs 2004 18 827 844
- (2004) CNS Drugs , vol.18 , pp. 827-844
- Schmitt, B.¹ Bernhardt, T.² Moeller, H.J.³ Heuser, I.⁴ Frolich, L.⁵

9
- 84964310836
- S.-S. Xie J.-S. Lan X.-B. Wang N. Jiang G. Dong Z.-R. Li K. D. G. Wang P.-P. Guo L.-Y. Kong Eur. J. Med. Chem. 2015 93 42 50
- (2015) Eur. J. Med. Chem. , vol.93 , pp. 42-50
- Xie, S.-S.¹ Lan, J.-S.² Wang, X.-B.³ Jiang, N.⁴ Dong, G.⁵ Li, Z.-R.⁶ Wang, K.D.G.⁷ Guo, P.-P.⁸ Kong, L.-Y.⁹

10
- 39149091398
- A. Cavalli M. L. Bolognesi A. Minarini M. Rosini V. Tumiatti M. Recanatini C. Melchiorre J. Med. Chem. 2008 51 347 372
- (2008) J. Med. Chem. , vol.51 , pp. 347-372
- Cavalli, A.¹ Bolognesi, M.L.² Minarini, A.³ Rosini, M.⁴ Tumiatti, V.⁵ Recanatini, M.⁶ Melchiorre, C.⁷

11
- 84856914519
- M. I. Fernandez-Bachiller C. Perez L. Monjas J. Rademann M. I. Rodriguez-Franco J. Med. Chem. 2012 55 1303 1317
- (2012) J. Med. Chem. , vol.55 , pp. 1303-1317
- Fernandez-Bachiller, M.I.¹ Perez, C.² Monjas, L.³ Rademann, J.⁴ Rodriguez-Franco, M.I.⁵

12
- 0019972810
- R. T. Bartus R. L. Dean, 3rd B. Beer A. S. Lippa Science 1982 217 408 414
- (1982) Science , vol.217 , pp. 408-414
- Bartus, R.T.¹ Dean, R.L.² Beer, B.³ Lippa, A.S.⁴

13
- 0032910197
- P. T. Francis A. M. Palmer M. Snape G. K. Wilcock J. Neurol.; Neurosurg. Psychiatry 1999 66 137 147
- (1999) J. Neurol.; Neurosurg. Psychiatry , vol.66 , pp. 137-147
- Francis, P.T.¹ Palmer, A.M.² Snape, M.³ Wilcock, G.K.⁴

14
- 0035661483
- D. N. H. Greig T. Utsuki Q. S. Yu X. X. Zhu H. W. Holloway T. Perry B. Lee D. K. Ingram D. K. Lahiri Curr. Med. Res. Opin. 2001 17 159 165
- (2001) Curr. Med. Res. Opin. , vol.17 , pp. 159-165
- Greig, D.N.H.¹ Utsuki, T.² Yu, Q.S.³ Zhu, X.X.⁴ Holloway, H.W.⁵ Perry, T.⁶ Lee, B.⁷ Ingram, D.K.⁸ Lahiri, D.K.⁹

15
- 84877665106
- A. Nordberg C. Ballard R. Bullock T. Darreh-Shori M. Somogyi Prim. Care Companion CNS Disord. 2013 15 10.4088/PCC.12r01412
- (2013) Prim. Care Companion CNS Disord. , vol.15
- Nordberg, A.¹ Ballard, C.² Bullock, R.³ Darreh-Shori, T.⁴ Somogyi, M.⁵

16
- 45749094206
- M. Harel L. K. Sonoda I. Silman J. L. Sussman T. L. Rosenberry J. Am. Chem. Soc. 2008 130 7856 7861
- (2008) J. Am. Chem. Soc. , vol.130 , pp. 7856-7861
- Harel, M.¹ Sonoda, L.K.² Silman, I.³ Sussman, J.L.⁴ Rosenberry, T.L.⁵

17
- 0025778840
- J. L. Sussman M. Harel F. Frolow C. Oefner A. Goldman L. Toker I. Silman Science 1991 253 872 879
- (1991) Science , vol.253 , pp. 872-879
- Sussman, J.L.¹ Harel, M.² Frolow, F.³ Oefner, C.⁴ Goldman, A.⁵ Toker, L.⁶ Silman, I.⁷

18
- 84861048527
- Y. Chen J. Sun L. Fang M. Liu S. Peng H. Liao J. Lehmann Y. Zhang J. Med. Chem. 2012 55 4309 4321
- (2012) J. Med. Chem. , vol.55 , pp. 4309-4321
- Chen, Y.¹ Sun, J.² Fang, L.³ Liu, M.⁴ Peng, S.⁵ Liao, H.⁶ Lehmann, J.⁷ Zhang, Y.⁸

19
- 0032507788
- S. L. Rogers R. S. Doody R. C. Mohs L. T. Friedhoff G. Donepezil Study Arch. Intern. Med. 1998 158 1021 1031
- (1998) Arch. Intern. Med. , vol.158 , pp. 1021-1031
- Rogers, S.L.¹ Doody, R.S.² Mohs, R.C.³ Friedhoff, L.T.⁴ Donepezil Study, G.⁵

20
- 84946570790
- K. O. Yerdelen M. Koca B. Anil H. Sevindik Z. Kasap Z. Halici K. Turkaydin G. Gunesacar Bioorg. Med. Chem. Lett. 2015 25 5576 5582
- (2015) Bioorg. Med. Chem. Lett. , vol.25 , pp. 5576-5582
- Yerdelen, K.O.¹ Koca, M.² Anil, B.³ Sevindik, H.⁴ Kasap, Z.⁵ Halici, Z.⁶ Turkaydin, K.⁷ Gunesacar, G.⁸

21
- 11144354610
- J. L. Marco C. de los Rios A. G. Garcia M. Villarroya M. C. Carreiras C. Martins A. Eleuterio A. Morreale M. Orozco F. J. Luque Bioorg. Med. Chem. 2004 12 2199 2218
- (2004) Bioorg. Med. Chem. , vol.12 , pp. 2199-2218
- Marco, J.L.¹ De Los Rios, C.² Garcia, A.G.³ Villarroya, M.⁴ Carreiras, M.C.⁵ Martins, C.⁶ Eleuterio, A.⁷ Morreale, A.⁸ Orozco, M.⁹ Luque, F.J.¹⁰

22
- 84903304059
- X. Wang W. Wang L. Li G. Perry H.-G. Lee X. Zhu Biochim. Biophys. Acta, Mol. Basis Dis. 2014 1842 1240 1247
- (2014) Biochim. Biophys. Acta, Mol. Basis Dis. , vol.1842 , pp. 1240-1247
- Wang, X.¹ Wang, W.² Li, L.³ Perry, G.⁴ Lee, H.-G.⁵ Zhu, X.⁶

23
- 75949121583
- M. A. Ansari S. W. Scheff J. Neuropathol. Exp. Neurol. 2010 69 155 167
- (2010) J. Neuropathol. Exp. Neurol. , vol.69 , pp. 155-167
- Ansari, M.A.¹ Scheff, S.W.²

24
- 77957237705
- K. Beking A. Vieira Public Health Nutr. 2010 13 1403 1409
- (2010) Public Health Nutr. , vol.13 , pp. 1403-1409
- Beking, K.¹ Vieira, A.²

25
- 84889246292
- Z. Luo J. Sheng Y. Sun C. Lu J. Yan A. Liu H.-B. Luo L. Huang X. Li J. Med. Chem. 2013 56 9089 9099
- (2013) J. Med. Chem. , vol.56 , pp. 9089-9099
- Luo, Z.¹ Sheng, J.² Sun, Y.³ Lu, C.⁴ Yan, J.⁵ Liu, A.⁶ Luo, H.-B.⁷ Huang, L.⁸ Li, X.⁹

26
- 84923350577
- M. Benchekroun M. Bartolini J. Egea A. Romero E. Soriano M. Pudlo V. Luzet V. Andrisano M.-L. Jimeno M. G. Lopez S. Wehle T. Gharbi B. Refouvelet L. de Andres C. Herrera-Arozamena B. Monti M. L. Bolognesi M. Isabel Rodriguez-Franco M. Decker J. Marco-Contelles L. Ismaili ChemMedChem 2015 10 523 539
- (2015) ChemMedChem , vol.10 , pp. 523-539
- Benchekroun, M.¹ Bartolini, M.² Egea, J.³ Romero, A.⁴ Soriano, E.⁵ Pudlo, M.⁶ Luzet, V.⁷ Andrisano, V.⁸ Jimeno, M.-L.⁹ Lopez, M.G.¹⁰ Wehle, S.¹¹ Gharbi, T.¹² Refouvelet, B.¹³ De Andres, L.¹⁴ Herrera-Arozamena, C.¹⁵ Monti, B.¹⁶ Bolognesi, M.L.¹⁷ Isabel Rodriguez-Franco, M.¹⁸ Decker, M.¹⁹ Marco-Contelles, J.²⁰ Ismaili, L.²¹ more..

27
- 84937680699
- R. Farina L. Pisani M. Catto O. Nicolotti D. Gadaleta N. Denora R. Soto-Otero E. Mendez-Alvarez C. S. Passos G. Muncipinto C. D. Altomare A. Nurisso P.-A. Carrupt A. Carotti J. Med. Chem. 2015 58 5561 5578
- (2015) J. Med. Chem. , vol.58 , pp. 5561-5578
- Farina, R.¹ Pisani, L.² Catto, M.³ Nicolotti, O.⁴ Gadaleta, D.⁵ Denora, N.⁶ Soto-Otero, R.⁷ Mendez-Alvarez, E.⁸ Passos, C.S.⁹ Muncipinto, G.¹⁰ Altomare, C.D.¹¹ Nurisso, A.¹² Carrupt, P.-A.¹³ Carotti, A.¹⁴

28
- 84921395943
- M. Benchekroun L. Ismaili M. Pudlo V. Luzet T. Gharbi B. Refouvelet J. Marco-Contelles Future Med. Chem. 2015 7 15 21
- (2015) Future Med. Chem. , vol.7 , pp. 15-21
- Benchekroun, M.¹ Ismaili, L.² Pudlo, M.³ Luzet, V.⁴ Gharbi, T.⁵ Refouvelet, B.⁶ Marco-Contelles, J.⁷

29
- 61849147931
- E. Barone V. Calabrese C. Mancuso Biogerontology 2009 10 97 108
- (2009) Biogerontology , vol.10 , pp. 97-108
- Barone, E.¹ Calabrese, V.² Mancuso, C.³

30
- 0036264981
- J. Kanski M. Aksenova A. Stoyanova D. A. Butterfield J. Nutr. Biochem. 2002 13 273 281
- (2002) J. Nutr. Biochem. , vol.13 , pp. 273-281
- Kanski, J.¹ Aksenova, M.² Stoyanova, A.³ Butterfield, D.A.⁴

31
- 84937422538
- A. Sgarbossa D. Giacomazza M. di Carlo Nutrients 2015 7 5764 5782
- (2015) Nutrients , vol.7 , pp. 5764-5782
- Sgarbossa, A.¹ Giacomazza, D.² Di Carlo, M.³

32
- 84928390457
- A. Al Maruf H. Lip H. Wong P. J. O'Brien Chem.-Biol. Interact. 2015 234 96 104
- (2015) Chem.-Biol. Interact. , vol.234 , pp. 96-104
- Al Maruf, A.¹ Lip, H.² Wong, H.³ O'Brien, P.J.⁴

33
- 84994406793
- Y. Shen H. Zhang L. Wang H. Qian Y. Qi X. Miao L. Cheng X. Qi Cell. Mol. Biol. 2016 62 109 116
- (2016) Cell. Mol. Biol. , vol.62 , pp. 109-116
- Shen, Y.¹ Zhang, H.² Wang, L.³ Qian, H.⁴ Qi, Y.⁵ Miao, X.⁶ Cheng, L.⁷ Qi, X.⁸

34
- 0016531540
- U. Reichman K. A. Watanabe J. J. Fox Carbohydr. Res. 1975 42 233 240
- (1975) Carbohydr. Res. , vol.42 , pp. 233-240
- Reichman, U.¹ Watanabe, K.A.² Fox, J.J.³

35
- 84906266231
- J. E. Chojnacki K. Liu X. Yan S. Toldo T. Selden M. Estrada M. Isabel Rodriguez-Franco M. S. Halquist D. Ye S. Zhang ACS Chem. Neurosci. 2014 5 690 699
- (2014) ACS Chem. Neurosci. , vol.5 , pp. 690-699
- Chojnacki, J.E.¹ Liu, K.² Yan, X.³ Toldo, S.⁴ Selden, T.⁵ Estrada, M.⁶ Isabel Rodriguez-Franco, M.⁷ Halquist, M.S.⁸ Ye, D.⁹ Zhang, S.¹⁰

36
- 44749093175
- H. Hatcher R. Planalp J. Cho F. M. Tortia S. V. Torti Cell. Mol. Life Sci. 2008 65 1631 1652
- (2008) Cell. Mol. Life Sci. , vol.65 , pp. 1631-1652
- Hatcher, H.¹ Planalp, R.² Cho, J.³ Tortia, F.M.⁴ Torti, S.V.⁵

37
- 84880540065
- A. Stergiou A. Bariotaki D. Kalaitzakis I. Smonou J. Org. Chem. 2013 78 7268 7273
- (2013) J. Org. Chem. , vol.78 , pp. 7268-7273
- Stergiou, A.¹ Bariotaki, A.² Kalaitzakis, D.³ Smonou, I.⁴

38
- 33644811612
- G. L. Ellman K. D. Courtney V. Andres Jr. R. M. Feather-Stone Biochem. Pharmacol. 1961 7 88 95
- (1961) Biochem. Pharmacol. , vol.7 , pp. 88-95
- Ellman, G.L.¹ Courtney, K.D.² Andres, V.³ Feather-Stone, R.M.⁴

39
- 0030902648
- N. J. Miller C. A. RiceEvans Free Radical Res. 1997 26 195 199
- (1997) Free Radical Res. , vol.26 , pp. 195-199
- Miller, N.J.¹ RiceEvans, C.A.²

40
- 72949088677
- R. A. Himes G. Y. Park G. S. Siluvai N. J. Blackburn K. D. Karlin Angew. Chem.; Int. Ed. 2008 47 9224 9227
- (2008) Angew. Chem.; Int. Ed. , vol.47 , pp. 9224-9227
- Himes, R.A.¹ Park, G.Y.² Siluvai, G.S.³ Blackburn, N.J.⁴ Karlin, K.D.⁵

41
- 84951761938
- M. Y. Wu G. Esteban S. Brogi M. Shionoya L. Wang G. Campiani M. Unzeta T. Inokuchi S. Butini J. Marco-Contelles Eur. J. Med. Chem. 2015 10.1016/j.ejmech.2015.10.001
- (2015) Eur. J. Med. Chem.
- Wu, M.Y.¹ Esteban, G.² Brogi, S.³ Shionoya, M.⁴ Wang, L.⁵ Campiani, G.⁶ Unzeta, M.⁷ Inokuchi, T.⁸ Butini, S.⁹ Marco-Contelles, J.¹⁰

42
- 84055217642
- I. Bolea J. Juarez-Jimenez C. de Los Rios M. Chioua R. Pouplana F. J. Luque M. Unzeta J. Marco-Contelles A. Samadi J. Med. Chem. 2011 54 8251 8270
- (2011) J. Med. Chem. , vol.54 , pp. 8251-8270
- Bolea, I.¹ Juarez-Jimenez, J.² De Los Rios, C.³ Chioua, M.⁴ Pouplana, R.⁵ Luque, F.J.⁶ Unzeta, M.⁷ Marco-Contelles, J.⁸ Samadi, A.⁹

43
- 2442457913
- R. Sultana S. Newman H. Mohmmad-Abdul J. N. Keller D. A. Butterfield Free Radical Res. 2004 38 449 458
- (2004) Free Radical Res. , vol.38 , pp. 449-458
- Sultana, R.¹ Newman, S.² Mohmmad-Abdul, H.³ Keller, J.N.⁴ Butterfield, D.A.⁵

44
- 80051842687
- S.-L. Hwang G.-C. Yen J. Agric. Food Chem. 2008 56 859 864
- (2008) J. Agric. Food Chem. , vol.56 , pp. 859-864
- Hwang, S.-L.¹ Yen, G.-C.²

45
- 77953940704
- J. A. Duce A. I. Bush Prog. Neurobiol. 2010 92 1 18
- (2010) Prog. Neurobiol. , vol.92 , pp. 1-18
- Duce, J.A.¹ Bush, A.I.²

46
- 84880915278
- C. Lu Y. Guo J. Yan Z. Luo H.-B. Luo M. Yan L. Huang X. Li J. Med. Chem. 2013 56 5843 5859
- (2013) J. Med. Chem. , vol.56 , pp. 5843-5859
- Lu, C.¹ Guo, Y.² Yan, J.³ Luo, Z.⁴ Luo, H.-B.⁵ Yan, M.⁶ Huang, L.⁷ Li, X.⁸

47
- 84900336722
- B. López-Iglesias C. Pérez J. A. Morales-García S. Alonso-Gil A. Pérez-Castillo A. Romero M. G. López M. Villarroya S. Conde M. I. Rodríguez-Franco J. Med. Chem. 2014 57 3773 3785
- (2014) J. Med. Chem. , vol.57 , pp. 3773-3785
- López-Iglesias, B.¹ Pérez, C.² Morales-García, J.A.³ Alonso-Gil, S.⁴ Pérez-Castillo, A.⁵ Romero, A.⁶ López, M.G.⁷ Villarroya, M.⁸ Conde, S.⁹ Rodríguez-Franco, M.I.¹⁰

48
- 84939424664
- F. Ehret M. Bubrin S. Záliš W. Kaim Chem.-Eur. J. 2015 21 12275 12278
- (2015) Chem.-Eur. J. , vol.21 , pp. 12275-12278
- Ehret, F.¹ Bubrin, M.² Záliš, S.³ Kaim, W.⁴

49
- 84962359573
- L. Di E. H. Kerns K. Fan O. J. McConnell G. T. Carter Eur. J. Med. Chem. 2003 38 223 232
- (2003) Eur. J. Med. Chem. , vol.38 , pp. 223-232
- Di, L.¹ Kerns, E.H.² Fan, K.³ McConnell, O.J.⁴ Carter, G.T.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.