Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy

Laboratory Investigation

Volumn 96, Issue 6, 2016, Pages 610-622

  Cao, Ai Li ^a   Wang, Li ^a   Chen, Xia ^a   Wang, Yun Man ^a   Guo, Heng Jiang ^a   Chu, Shuang ^a   Liu, Cheng ^a   Zhang, Xue Mei ^b   Peng, Wen ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 PHENYLBUTYRIC ACID; ACTIVATING TRANSCRIPTION FACTOR 6; ALBUMIN; BECLIN 1; CASPASE 12; CASPASE 3; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; INSULIN; PROTEIN IRE1; URSODEOXYCHOLIC ACID; X BOX BINDING PROTEIN 1; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; LEPTIN RECEPTOR; LEPTIN RECEPTOR, MOUSE;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BODY WEIGHT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; EXPERIMENTAL DIABETIC NEPHROPATHY; FLUID INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; KIDNEY HYPERTROPHY; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION; SYSTOLIC BLOOD PRESSURE; URINE VOLUME; ANIMAL; BLOOD; C57BL MOUSE; CELL CULTURE; DIABETIC NEPHROPATHIES; DRUG EFFECTS; GENETICS; INSULIN RESISTANCE; METABOLISM; MUTANT MOUSE STRAIN; MUTATION; PATHOLOGY;

ALBUMINURIA; ANIMALS; APOPTOSIS; AUTOPHAGY; CELLS, CULTURED; DIABETIC NEPHROPATHIES; ENDOPLASMIC RETICULUM STRESS; GLUCOSE TOLERANCE TEST; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTATION; PHENYLBUTYRATES; PODOCYTES; RECEPTORS, LEPTIN; URSODEOXYCHOLIC ACID;

EID: 84970998207     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2016.44     Document Type: Article

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