Attenuation of diabetic nephropathy by Chaihuang-Yishen granule through anti-inflammatory mechanism in streptozotocin-induced rat model of diabetics

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 556-564

  Zhang, Haojun ^a   Zhao, Tingting ^a   Gong, Yuewen ^b   Dong, Xi ^a   Zhang, Weiku ^a   Sun, Sifan ^a   Wang, Hua ^a   Gu, Yanting ^a   Lu, Xiaoguang ^c   Yan, Meihua ^a   Li, Ping ^a  

^a CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^b UNIVERSITY OF MANITOBA   (Canada)

^c INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

Anti inflammatory; Chinese herbs; Diabetic nephropathy; NF B

Indexed keywords

ALBUMIN; CHAIHUANG YISHEN; CHOLESTEROL; CREATININE; FOSINOPRIL; GLUCOSE; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; GLOMERULUS CAPILLARY; GLUCOSE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; KIDNEY FUNCTION; KIDNEY HYPERTROPHY; KIDNEY INJURY; KIDNEY STRUCTURE; KIDNEY TUBULE PRESSURE; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; PROTEINURIA; RAT; RAT MODEL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; UNINEPHRECTOMY; UREA NITROGEN BLOOD LEVEL; URINARY EXCRETION;

RATTUS;

ACEI; ANGIOTENSIN CONVERTING ENZYME INHIBITOR; ANGIOTENSIN RECEPTOR BLOCKER; ANTI-INFLAMMATORY; ARB; BMPRII; BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE II; BUN; CHAIHUANG-YISHEN GRANULE; CHINESE HERBS; CHYS; CRE; CREATININE; DIABETIC NEPHROPATHY; DN; EMT; EPITHELIAL-MESENCHYMAL TRANSITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY.; HPLC; IL-1Β; INHIBITORY PROTEINS OF NUCLEAR FACTOR KAPPAB; INTERLEUKIN-1BETA; IΚB; MCP-1; MONOCYTE CHEMOTACTIC PEPTIDE-1; NF-ΚB; NUCLEAR FACTOR KAPPAB; PAN; PUROMYCIN AMINONUCLEOSIDE; STREPTOZOTOCIN; STZ; TC; TCM; TG; TGF-Β1; TNF-Α; TOTAL CHOLESTEROL; TRADITIONAL CHINESE MEDICINE; TRANSFORMING GROWTH FACTOR-BETA1; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA; UREA NITROGEN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOOD GLUCOSE; CHEMOKINE CCL2; DIABETES MELLITUS, EXPERIMENTAL; DRUG ADMINISTRATION SCHEDULE; DRUGS, CHINESE HERBAL; FOSINOPRIL; GENE EXPRESSION REGULATION; HYPOGLYCEMIC AGENTS; KIDNEY; MALE; MOLECULAR STRUCTURE; RATS; RATS, WISTAR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84891495679     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.11.020     Document Type: Article

References (48)

1. E.M. Abdel-Rahman, L. Saadulla, W.B. Reeves, and A.S. Awad Therapeutic modalities in diabetic nephropathy: standard and emerging approaches J. Gen. Internal Med. 27 2012 458 468
2. H. Abe, T. Matsubara, H. Arai, and T. Doi Role of Smad1 in diabetic nephropathy: molecular mechanisms and implications as a diagnostic marker Histol. Histopathol. 26 2011 531 541
3. W.W. Chao, Y.H. Hong, M.L. Chen, and B.F. Lin Inhibitory effects of Angelica sinensis ethyl acetate extract and major compounds on NF-kappaB trans-activation activity and LPS-induced inflammation J. Ethnopharmacol. 129 2010 244 249
4. F.Y. Chow, D.J. Nikolic-Paterson, F.Y. Ma, E. Ozols, B.J. Rollins, and G.H. Tesch Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice Diabetologia 50 2007 471 480
5. F.Y. Chow, D.J. Nikolic-Paterson, E. Ozols, R.C. Atkins, B.J. Rollin, and G.H. Tesch Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice Kidney Int. 69 2006 73 80
6. M.E. Cooper Diabetes: treating diabetic nephropathy-still an unresolved issue Nat. Rev. Endocrinol. 8 2012 515 516
7. K. DiPetrillo, B. Coutermarsh, and F.A. Gesek Urinary tumor necrosis factor contributes to sodium retention and renal hypertrophy during diabetes Am. J. Physiol. Renal Physiol. 284 2003 F113 121
8. A.A. Elmarakby, R. Abdelsayed, J. Yao Liu, and M.S. Mozaffari Inflammatory cytokines as predictive markers for early detection and progression of diabetic nephropathy EPMA J. 1 2010 117 129
9. M. Gao, J.H. Zhang, F.X. Zhou, C.H. Xie, G. Han, S.Q. Fang, and Y.F. Zhou Angelica sinensis suppresses human lung adenocarcinoma A549 cell metastasis by regulating MMPs/TIMPs and TGF-beta1 Oncol. Rep. 27 2011 585 593
10. C.E. Hills, and P.E. Squires The role of TGF-beta and epithelial-to mesenchymal transition in diabetic nephropathy Cytokine Growth Factor Rev. 22 2011 131 139
11. M.A. Hofmann, S. Schiekofer, B. Isermann, M. Kanitz, M. Henkels, M. Joswig, A. Treusch, M. Morcos, T. Weiss, V. Borcea, A.K. Abdel Khalek, J. Amiral, H. Tritschler, E. Ritz, P. Wahl, R. Ziegler, A. Bierhaus, and P.P. Nawroth Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB Diabetologia 42 1999 222 232
12. R.L. Hoo, J.Y. Wong, C. Qiao, A. Xu, H. Xu, and K.S. Lam The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity Nutr. Metab. (London) 7 2010 67
13. M. Iwamoto, S. Mizuiri, M. Arita, and H. Hemmi Nuclear factor-kappaB activation in diabetic rat kidney: evidence for involvement of P-selectin in diabetic nephropathy Tohoku J. Exp. Med. 206 2005 163 171
14. Y.W. Jiang, H. Li, Y.Y. Zhang, W. Li, Y.F. Jiang, Y.Y. Ou, and D.F. Chen Beneficial effect of Bupleurum polysaccharides on autoimmune-prone MRL-lpr mice Clin. Dev. Immunol. 2012 2012 842928
15. H. Kanamori, T. Matsubara, A. Mima, E. Sumi, K. Nagai, T. Takahashi, H. Abe, N. Iehara, A. Fukatsu, H. Okamoto, T. Kita, T. Doi, and H. Arai Inhibition of MCP-1/CCR2 pathway ameliorates the development of diabetic nephropathy Biochem. Biophys. Res. Commun. 360 2007 772 777
16. M.J. Kim, H.N. Kim, K.S. Kang, N.I. Baek, D.K. Kim, Y.S. Kim, B.H. Jeon, and S.H. Kim Methanol extract of Dioscoreae Rhizoma inhibits pro-inflammatory cytokines and mediators in the synoviocytes of rheumatoid arthritis Int. Immunopharmacol. 4 2004 1489 1497
17. H.Y. Lan Transforming growth factor-beta/Smad signalling in diabetic nephropathy Clin. Exp. Pharmacol. Physiol. 39 2012 731 738
18. P. Li, J. Yan, Y. Sun, F.J. Burczynski, and Y. Gong Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins Nephrology (Carlton) 12 2007 466 473
19. W.L. Li, H.C. Zheng, J. Bukuru, and N. De Kimpe Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus J. Ethnopharmacol. 92 2004 1 21
20. A.K. Lim, and G.H. Tesch Inflammation in diabetic nephropathy Mediators Inflamm. 2012 2012 146154
21. B. Lu, Y. Xu, L. Xu, X. Cong, L. Yin, H. Li, and J. Peng Mechanism investigation of dioscin against CCl4-induced acute liver damage in mice Environ. Toxicol. Pharmacol. 34 2012 127 135
22. D. Luis-Rodriguez, A. Martinez-Castelao, J.L. Gorriz, F. De-Alvaro, and J.F. Navarro-Gonzalez Pathophysiological role and therapeutic implications of inflammation in diabetic nephropathy World J. Diabetes 3 2012 7 18
23. T.A. McGowan, Y. Zhu, and K. Sharma Transforming growth factor-beta: a clinical target for the treatment of diabetic nephropathy Curr. Diabetes Rep. 4 2004 447 454
24. S. Mezzano, C. Aros, A. Droguett, M.E. Burgos, L. Ardiles, C. Flores, H. Schneider, M. Ruiz-Ortega, and J. Egido NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy Nephrol. Dialysis, Transplantation 19 2004 2505 2512
25. S.W. Min, S.N. Ryu, and D.H. Kim Anti-inflammatory effects of black rice, cyanidin-3-O-beta-d-glycoside, and its metabolites, cyanidin and protocatechuic acid Int. Immunopharmacol. 10 2010 959 966
26. Y. Moriwaki, T. Inokuchi, A. Yamamoto, T. Ka, Z. Tsutsumi, S. Takahashi, and T. Yamamoto Effect of TNF-alpha inhibition on urinary albumin excretion in experimental diabetic rats Acta Diabetol. 44 2007 215 218
27. B.Y. Nam, J. Paeng, S.H. Kim, S.H. Lee, Kim do, H. Kang, H.Y. Li, J.J. Kwak, S.J. Park, J.T. Yoo, T.H. Han, S.H. Kim, and D.K. Kang, S.W. The MCP-1/CCR2 axis in podocytes is involved in apoptosis induced by diabetic conditions Apoptosis 17 2012 1 13
28. J.F. Navarro-Gonzalez, A. Jarque, M. Muros, C. Mora, and J. Garcia Tumor necrosis factor-alpha as a therapeutic target for diabetic nephropathy Cytokine Growth Factor Rev. 20 2009 165 173
29. J. Park, D.R. Ryu, J.J. Li, D.S. Jung, S.J. Kwak, S.H. Lee, T.H. Yoo, S.H. Han, J.E. Lee, D.K. Kim, S.J. Moon, K. Kim, D.S. Han, and S.W. Kang MCP-1/CCR2 system is involved in high glucose-induced fibronectin and type IV collagen expression in cultured mesangial cells Am. J. Physiol. Renal Physiol. 295 2008 F749 757
30. A.O. Phillips, N. Topley, R. Steadman, K. Morrisey, and J.D. Williams Induction of TGF-beta 1 synthesis in d-glucose primed human proximal tubular cells by IL-1 beta and TNF alpha Kidney Int. 50 1996 1546 1554
31. Q. Qin, J. Niu, Z. Wang, W. Xu, Z. Qiao, and Y. Gu Astragalus membranaceus inhibits inflammation via phospho-P38 mitogen-activated protein kinase (MAPK) and nuclear factor (NF)-kappaB pathways in advanced glycation end product-stimulated macrophages Int. J. Mol. Sci. 13 2012 8379 8387
32. A.B. Sanz, M.D. Sanchez-Nino, A.M. Ramos, J.A. Moreno, B. Santamaria, M. Ruiz-Ortega, J. Egido, and A. Ortiz NF-kappaB in renal inflammation J. Am. Soc. Nephrol. 21 2010 1254 1262
33. H. Schmid, A. Boucherot, Y. Yasuda, A. Henger, B. Brunner, F. Eichinger, A. Nitsche, E. Kiss, M. Bleich, H.J. Grone, P.J. Nelson, D. Schlondorff, C.D. Cohen, and M. Kretzler Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy Diabetes 55 2006 2993 3003
34. J. Shan, J. Fu, Z. Zhao, X. Kong, H. Huang, L. Luo, and Z. Yin Chlorogenic acid inhibits lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 cells through suppressing NF-kappaB and JNK/AP-1 activation Int. Immunopharmacol. 9 2009 1042 1048
35. F.W. Tam, B.L. Riser, K. Meeran, J. Rambow, C.D. Pusey, and A.H. Frankel Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy Cytokine 47 2009 37 42
36. G.H. Tesch MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy Am. J. Physiol. Renal Physiol. 294 2008 F697 701
37. G.H. Tesch, and T.J. Allen Rodent models of streptozotocin-induced diabetic nephropathy Nephrology (Carlton) 12 2007 261 266
38. S.M. Titan, J.M. Vieira Jr., W.V. Dominguez, S.R. Moreira, A.B. Pereira, R.T. Barros, and R. Zatz Urinary MCP-1 and RBP: independent predictors of renal outcome in macroalbuminuric diabetic nephropathy J. Diabetes Complications 26 2012 546 553
39. J. Wada, and H. Makino Inflammation and the pathogenesis of diabetic nephropathy Clin. Sci. (London) 124 2013 139 152
40. T. Wada, K. Furuichi, N. Sakai, Y. Iwata, K. Yoshimoto, M. Shimizu, S.I. Takeda, K. Takasawa, M. Yoshimura, H. Kida, K.I. Kobayashi, N. Mukaida, T. Naito, K. Matsushima, and H. Yokoyama Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy Kidney Int. 58 2000 1492 1499
41. Y. Wang, Y. Zhu, L. Gao, H. Yin, Z. Xie, D. Wang, Z. Zhu, and X. Han Formononetin attenuates IL-1beta-induced apoptosis and NF-kappaB activation in INS-1 cells Molecules 17 2012 10052 10064
42. J.A. Wei, X. Zeng, L. Han, and Y. Huang The regulatory effects of polyporus polysaccharide on the nuclear factor kappa B signal pathway of bladder cancer cells stimulated by Bacillus Calmette-Guerin Chin. J. Integr. Med. 17 2011 531 536
43. C.H. Xie, M.S. Zhang, Y.F. Zhou, G. Han, Z. Cao, F.X. Zhou, G. Zhang, Z.G. Luo, J.P. Wu, H. Liu, J. Chen, and W.J. Zhang Chinese medicine Angelica sinensis suppresses radiation-induced expression of TNF-alpha and TGF-beta1 in mice Oncol. Rep. 15 2006 1429 1436
44. J.Y. Xie, H.Y. Di, H. Li, X.Q. Cheng, Y.Y. Zhang, and D.F. Chen Bupleurum chinense DC polysaccharides attenuates lipopolysaccharide-induced acute lung injury in mice Phytomedicine 19 2011 130 137
45. W. Xie, Y. Zhao, and Y. Zhang Traditional Chinese medicines in treatment of patients with type 2 diabetes mellitus Evid. Based Complementary Altern. Med. 2011 2011 726723
46. Y. Xu, L. Feng, S. Wang, Q. Zhu, J. Lin, C. Lou, P. Xiang, B. He, Z. Zheng, D. Tang, and G. Zuo Phytoestrogen calycosin-7-O-beta-d-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage J. Cell. Biochem. 112 2011 2953 2965
47. S.H. Yang, S.J. Shin, J.E. Oh, J.Z. Jin, N.H. Chung, C.S. Lim, S. Kim, and Y.S. Kim The protective role of uteroglobin through the modulation of tissue transglutaminase in the experimental crescentic glomerulonephritis Nephrol Dialysis, Transplantation 23 2008 3437 3445
48. H. Yuan, L. Lanting, Z.G. Xu, S.L. Li, P. Swiderski, S. Putta, M. Jonnalagadda, M. Kato, and R. Natarajan Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes Am. J. Physiol. Renal Physiol. 295 2008 F605 617