Hydrophobically modified inulin as an amphiphilic carbohydrate polymer for micellar delivery of paclitaxel for intravenous route

International Journal of Pharmaceutics

Volumn 500, Issue 1-2, 2016, Pages 32-41

  Muley, Pratik ^a   Kumar, Sunny ^a   El Kourati, Fadoua ^a   Kesharwani, Siddharth S ^a   Tummala, Hemachand ^a  

^a SOUTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Carbohydrate polymer; Inulin; Inutec SP1 ; Melanoma; Micelles; Paclitaxel; Xenograft

Indexed keywords

CARBAMIC ACID DERIVATIVE; CARBOHYDRATE; CREMOPHOR; INULIN; PACLITAXEL; POLYMER; ANTINEOPLASTIC AGENT; DRUG CARRIER; MICELLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; ENCAPSULATION; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICELLE; MICELLIZATION; MICROENVIRONMENT; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; TUMOR VOLUME; ZETA POTENTIAL; ANIMAL; C57BL MOUSE; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; ERYTHROCYTE; HEMOLYSIS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MELANOMA, EXPERIMENTAL; PATHOLOGY; TUMOR CELL LINE;

ADMINISTRATION, INTRAVENOUS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG LIBERATION; ERYTHROCYTES; HEMOLYSIS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INULIN; MALE; MELANOMA, EXPERIMENTAL; MICE, INBRED C57BL; MICELLES; PACLITAXEL; TUMOR BURDEN;

EID: 84970925777     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.01.005     Document Type: Article

References (42)

1. A.H. Abouzeid, N.R. Patel, and V.P. Torchilin Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer Int. J. Pharm. 464 2014 178 184
2. 1H NMR and solid-state thermal properties of inulin-d-α-tocopherol succinate (INVITE) micelles as drug delivery systems for hydrophobic drugs Macromol. Chem. Phys. 215 2014 2084 2096
3. Z. Daman, S. Ostad, M. Amini, and K. Gilani Preparation, optimization and in vitro characterization of stearoyl-gemcitabine polymeric micelles: A comparison with its self-assembled nanoparticles Int. J. Pharm. 468 2014 142 151
4. H. Deng, J. Liu, X. Zhao, Y. Zhang, J. Liu, S. Xu, L. Deng, A. Dong, and J. Zhang PEG-b-PCL Copolymer Micelles with the Ability of pH-controlled Negative-to-positive Charge Reversal for Intracellular Delivery of Doxorubicin Biomacromolecules 15 2014 4281 4292
5. H.H.P. Duong, and L.-Y.L. Yung Synergistic co-delivery of doxorubicin and paclitaxel using multi-functional micelles for cancer treatment Int. J. Pharm. 454 2013 486 495
6. ASTM F756-00 Standard Practice for Assessment of Hemolytic Properties of Materials 2000 ASTM International West Conshohocken PA, USA
7. A. Fischer, M.C. Houzelle, P. Hubert, M.A.V. Axelos, C. Geoffroy-Chapotot, M.C. Carré, M.L. Viriot, and E. Dellacherie Detection of intramolecular associations in hydrophobically modified pectin derivatives using fluorescent probes Langmuir 14 1998 4482 4488
8. H. Gelderblom, J. Verweij, K. Nooter, and A. Sparreboom Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation Eur. J. Cancer 37 2001 1590 1598
9. J. Gong, M. Huo, J. Zhou, Y. Zhang, X. Peng, D. Yu, H. Zhang, and J. Li Synthesis, characterization, drug-loading capacity and safety of novel octyl modified serum albumin micelles Int. J. Pharm. 376 2009 161 168
10. H. Hatakeyama, H. Akita, and H. Harashima A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma Adv. Drug Deliv. Rev. 63 2011 152 160
11. C. Jiang, H. Wang, X. Zhang, Z. Sun, F. Wang, J. Cheng, H. Xie, B. Yu, and L. Zhou Deoxycholic acid-modified chitooligosaccharide/mPEG-PDLLA mixed micelles loaded with paclitaxel for enhanced antitumor efficacy Int. J. Pharm. 475 2014 60 68
12. K. Kataoka, T. Matsumoto, M. Yokoyama, T. Okano, Y. Sakurai, S. Fukushima, K. Okamoto, and G.S. Kwon Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance J. Control. Release 64 2000 143 153
13. H. Koide, T. Asai, K. Hatanaka, T. Urakami, T. Ishii, E. Kenjo, M. Nishihara, M. Yokoyama, T. Ishida, H. Kiwada, and N. Oku Particle size-dependent triggering of accelerated blood clearance phenomenon Int. J. Pharm. 362 2008 197 200
14. S. Kumar, S.S. Kesharwani, H. Mathur, M. Tyagi, G.J. Bhat, and H. Tummala Molecular complexation of curcumin with pH sensitive cationic copolymer enhances the aqueous solubility, stability and bioavailability of curcumin Eur. J. Pharm. Sci. 82 2015 86 96
15. M. Kurecic, M. Sfiligoj Smole, and K. Stana-Kleinschek Use of polysaccharide based surfactants to stabilize organically modified clay particles aqueous dispersion Carbohydr. Polym. 94 2013 687 694
16. G.S. Kwon, and T. Okano Polymeric micelles as new drug carriers Adv. Drug Deliv. Rev. 21 1996 107 116
17. N. Liang, S. Sun, X. Li, H. Piao, H. Piao, F. Cui, and L. Fang α-Tocopherol succinate-modified chitosan as a micellar delivery system for paclitaxel: preparation, characterization and in vitro/in vivo evaluations Int. J. Pharm. 423 2012 480 488
18. R.T. Liggins, W.L. Hunter, and H.M. Burt Solid-state characterization of paclitaxel J. Pharm. Sci. 86 1997 1458 1463
19. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 2000 271 284
20. M. Mahmoudzadeh, A. Fassihi, J. Emami, N.M. Davies, and F. Dorkoosh Physicochemical, pharmaceutical and biological approaches toward designing optimized and efficient hydrophobically modified chitosan-based polymeric micelles as a nanocarrier system for targeted delivery of anticancer drugs J. Drug Target. 21 2013 693 709
21. D. Mandracchia, G. Tripodo, A. Latrofa, and R. Dorati Amphiphilic inulin-d-α-tocopherol succinate (INVITE) bioconjugates for biomedical applications Carbohydr. Polym. 103 2014 46 54
22. K. Na, T. Bum Lee, K.-H. Park, E.-K. Shin, Y.-B. Lee, and H.-K. Choi Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anti-cancer drug delivery system Eur. J. Pharm. Sci. 18 2003 165 173
23. M. Nichifor, G. Mocanu, and M.C. Stanciu Micelle-like association of polysaccharides with hydrophobic end groups Carbohydr. Polym. 110 2014 209 218
24. T. Nishikawa, K. Akiyoshi, and J. Sunamoto Macromolecular complexation between bovine serum albumin and the self-assembled hydrogel nanoparticle of hydrophobized polysaccharides J. Am. Chem. Soc. 118 1996 6110 6115
25. K.N. Prasad, T.T. Luong, A.T. FlorenceJoelle Paris, C. Vaution, M. Seiller, and F. Puisieux Surface activity and association of ABA polyoxyethylene - polyoxypropylene block copolymers in aqueous solution J. Colloid Interface Sci. 69 1979 225 232
26. A. Sharma, R.M. Straubinger, I. Ojima, and R.J. Bernacki Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice J. Pharm. Sci. 84 1995 1400 1404
27. K. Shiraishi, M. Hamano, H. Ma, K. Kawano, Y. Maitani, T. Aoshi, K.J. Ishii, and M. Yokoyama Hydrophobic blocks of PEG-conjugates play a significant role in the accelerated blood clearance (ABC) phenomenon J. Control. Release 165 2013 183 190
28. X. Shuai, H. Ai, N. Nasongkla, S. Kim, and J. Gao Micellar carriers based on block copolymers of poly(ε-caprolactone) and poly(ethylene glycol) for doxorubicin delivery J. Control. Release. 98 2004 415 426
29. A.K. Singla, A. Garg, and D. Aggarwal Paclitaxel and its formulations Int. J. Pharm. 235 2002 179 192
30. C.V. Stevens, A. Meriggi, and K. Booten Chemical modification of inulin, a valuable renewable resource, and its industrial applications Biomacromolecules 2 2001 1 16
31. C.V. Stevens, A. Meriggi, M. Peristeropoulou, P.P. Christov, K. Booten, B. Levecke, A. Vandamme, N. Pittevils, and T.F. Tadros Polymeric surfactants based on inulin: a polysaccharide extracted from chicory. 1. Synthesis and interfacial properties Biomacromolecules 2 2001 1256 1259
32. G. Van den Mooter, I. Weuts, T. De Ridder, and N. Blaton Evaluation of Inutec® SP1 as a new carrier in the formulation of solid dispersions for poorly soluble drugs Int. J. Pharm. 316 2006 1 6
33. L. Vervoort, G. Van den Mooter, P. Augustijns, R. Busson, S. Toppet, and R. Kinget Inulin hydrogels as carriers for colonic drug targeting: I. Synthesis and characterization of methacrylated inulin and hydrogel formation Pharm. Res. 14 1997 1730 1737
34. C. Wang, Z.Q. Wang, and X. Zhang Amphiphilic building blocks for self-assembly: from amphiphiles to supra-amphiphiles Acc. Chem. Res. 45 2012 608 618
35. X.H. Wang, Q. Tian, W. Wang, C.N. Zhang, P. Wang, and Z. Yuan In vitro evaluation of polymeric micelles based on hydrophobically-modified sulfated chitosan as a carrier of doxorubicin J. Mater. Sci. 23 2012 1663 1674
36. M. Wu, K. Guo, H. Dong, R. Zeng, M. Tu, and J. Zhao In vitro drug release and biological evaluation of biomimetic polymeric micelles self-assembled from amphiphilic deoxycholic acid-phosphorylcholine-chitosan conjugate Mater. Sci. Eng. 45 2014 162 169
37. X. Yang, L. Li, Y. Wang, and Y. Tan Preparation, pharmacokinetics and tissue distribution of micelles made of reverse thermo-responsive polymers Int. J. Pharm. 370 2009 210 215
38. C. Zhang, P. Qineng, and H. Zhang Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system Colloids Surf. B 39 2004 69 75
39. N. Zhang, P.R. Wardwell, and R.A. Bader Polysaccharide-based micelles for drug delivery Pharmaceutics 5 2013 329 352
40. X. Zhang, H.M. Burt, G. Mangold, D. Dexter, D. Von Hoff, L. Mayer, and W.L. Hunter Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel Anti-cancer Drugs 8 1997 696 701
41. Z. Zhang, X. Xiong, J. Wan, L. Xiao, L. Gan, Y. Feng, H. Xu, and X. Yang Cellular uptake and intracellular trafficking of PEG-b-PLA polymeric micelles Biomaterials 33 2012 7233 7240
42. H. Zhu, F. Liu, J. Guo, J. Xue, Z. Qian, and Y. Gu Folate-modified chitosan micelles with enhanced tumor targeting evaluated by near infrared imaging system Carbohydr. Polym. 86 2011 1118 1129