Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform

Nucleic Acids Research

Volumn 44, Issue 9, 2016, Pages

  Wagner, Tobias ^a   Greschik, Holger ^a   Burgahn, Teresa ^a   Schmidtkunz, Karin ^a   Schott, Anne Kathrin ^a   McMillan, Joel ^a   Baranauskiene, Lina ^b   Xiong, Yan ^c   Fedorov, Oleg ^d   Jin, Jian ^c   Oppermann, Udo ^e   Matulis, Daumantas ^b   Schule, Roland ^a,f   Jung, Manfred ^a,g  

^a UNIVERSITY OF FREIBURG   (Germany)

^b VILNIUS UNIVERSITY   (Lithuania)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f German Cancer Consortium (DKTK)   (Germany)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BINDING PROTEIN; HISTONE DEMETHYLASE; HISTONE H3; JMJD2C PROTEIN; LIGAND; METHYLLYSINE; SPINDLIN1; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; KDM4C PROTEIN, HUMAN; LYSINE; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHOPROTEIN; PROTEIN BINDING; SPINDLIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING ASSAY; BINDING SITE; BIOSENSOR; CONTROLLED STUDY; EPIGENETICS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SCREENING; CHEMISTRY; GENETIC EPIGENESIS; GENETICS; HL-60 CELL LINE; METABOLISM; METHYLATION; PHYSIOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

CELL CYCLE PROTEINS; CELL LINE, TUMOR; EPIGENESIS, GENETIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HL-60 CELLS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LIGANDS; LYSINE; METHYLATION; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN DOMAINS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84970006727     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw089     Document Type: Article

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