Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 6, 2010, Pages 863-870

  Baranauskiene, Lina ^a   Hilvo, Mika ^b   Matuliene, Jurgita ^a   Golovenko, Dmitrij ^a   Manakova, Elena ^a   Dudutien, Virginija ^a   Michailovien, Vilma ^a   Torresan, Jolanta ^a   Jachno, Jelena ^a   Parkkila, Seppo ^b,c   Maresca, Alfonso ^d   Supuran, Claudiu T ^d   Gražulis, Saulius ^a   Matulis, Daumantas ^a  

^a VILNIUS UNIVERSITY   (Lithuania)

^b UNIVERSITY OF TAMPERE   (Finland)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Inhibition; Isothermal titration calorimetry; Sulphonamides; Thermal shift assay; X ray crystallography

Indexed keywords

BENZIMIDAZO[1,2 C][1,2,3]THIADIAZOLE 7 SULPHONAMIDE DERIVATIVE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE IX; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DRUG INHIBITION; DRUG PROTEIN BINDING; ENZYME INHIBITION; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; CALORIMETRY; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; KINETICS; LIGANDS; MOLECULAR CONFORMATION; RECOMBINANT PROTEINS; SULFONAMIDES; THIADIAZOLES;

EID: 77958022642     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360903571685     Document Type: Article

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