Small-molecule ligands of methyl-lysine binding proteins

Journal of Medicinal Chemistry

Volumn 54, Issue 7, 2011, Pages 2504-2511

  Herold, J Martin ^a   Wigle, Tim J ^a   Norris, Jacqueline L ^a   Lam, Robert ^b   Korboukh, Victoria K ^a   Gao, Cen ^a   Ingerman, Lindsey A ^a   Kireev, Dmitri B ^a   Senisterra, Guillermo ^b   Vedadi, Masoud ^b   Tripathy, Ashutosh ^c   Brown, Peter J ^b   Arrowsmith, Cheryl H ^b   Jin, Jian ^a   Janzen, William P ^a   Frye, Stephen V ^a  

^a University of North Carolina   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HISTONE; LIGAND; LYSINE DERIVATIVE; PROTEIN MBT; RETINOBLASTOMA PROTEIN; SMALL MOLECULE METHYL LYSINE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMOLUMINESCENCE; CHROMATIN STRUCTURE; CRYSTAL STRUCTURE; EPIGENETICS; LIGAND BINDING; METHYLATION; MOLECULAR RECOGNITION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CALORIMETRY; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; LUMINESCENT MEASUREMENTS; LYSINE; METHYLATION; MODELS, MOLECULAR; NUCLEAR PROTEINS; PEPTIDOMIMETICS; PROTEIN STRUCTURE, TERTIARY; SMALL MOLECULE LIBRARIES;

EID: 79953783228     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200045v     Document Type: Article

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