메뉴 건너뛰기




Volumn 11, Issue 5, 2016, Pages 613-638

Scientific advances in lung cancer 2015

(37)  Tsao, Anne S a   Scagliotti, Giorgio V b   Bunn, Paul A c   Carbone, David P d   Warren, Graham W e   Bai, Chunxue f   De Koning, Harry J g   Uraujh Yousaf Khan, A g   McWilliams, Annette h   Tsao, Ming Sound i   Adusumilli, Prasad S j   Rami Porta, Ramón k,l   Asamura, Hisao m   Van Schil, Paul E n   Darling, Gail E o   Ramalingam, Suresh S p   Gomez, Daniel R a   Rosenzweig, Kenneth E q   Zimmermann, Stefan r   Peters, Solange s   more..


Author keywords

Adjuvant chemotherapy; Biomarkers; Cancer prevention; Gene mutations; Immunotherapy; Lung cancer; Master protocols; Pathology; Radiotherapy; Screening; Smoking cessation; Staging; Surgery; Targeted therapy; Value of therapy

Indexed keywords

B RAF KINASE; BIOLOGICAL MARKER; K RAS PROTEIN; NERVE GROWTH FACTOR RECEPTOR; PROTEIN RET; SCATTER FACTOR RECEPTOR;

EID: 84969833490     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1016/j.jtho.2016.03.012     Document Type: Review
Times cited : (247)

References (256)
  • 1
    • 84962812153 scopus 로고    scopus 로고
    • Small cell lung cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?
    • Bunn PA Jr, Minna J, Augustyn A, et al. Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes? J Thorac Oncol. 2016;11:453-474.
    • (2016) J Thorac Oncol , vol.11 , pp. 453-474
    • Bunn, P.A.1    Minna, J.2    Augustyn, A.3
  • 3
    • 0031749664 scopus 로고    scopus 로고
    • Lung cancer and passive smoking
    • Hackshaw AK. Lung cancer and passive smoking. Stat Methods Med Res. 1998;7:119-136.
    • (1998) Stat Methods Med Res , vol.7 , pp. 119-136
    • Hackshaw, A.K.1
  • 4
    • 84872816560 scopus 로고    scopus 로고
    • 50-year trends in smoking-related mortality in the United States
    • Thun MJ, Carter BD, Feskanich D, et al. 50-year trends in smoking-related mortality in the United States. N Engl J Med. 2013;368:351-364.
    • (2013) N Engl J Med , vol.368 , pp. 351-364
    • Thun, M.J.1    Carter, B.D.2    Feskanich, D.3
  • 5
    • 84940662246 scopus 로고    scopus 로고
    • Emerging tobacco-related cancer risks in China: A nationwide, prospective study of 0.5 million adults
    • Chen ZM, Peto R, Iona A, et al. Emerging tobacco-related cancer risks in China: a nationwide, prospective study of 0.5 million adults. Cancer. 2015;121(suppl 17):3097-3106.
    • (2015) Cancer , vol.121 , pp. 3097-3106
    • Chen, Z.M.1    Peto, R.2    Iona, A.3
  • 6
    • 84908569070 scopus 로고    scopus 로고
    • The biological and clinical effects of smoking by patients with cancer and strategies to implement evidence-based tobacco cessation support
    • Warren GW, Sobus S, Gritz ER. The biological and clinical effects of smoking by patients with cancer and strategies to implement evidence-based tobacco cessation support. Lancet Oncol. 2014;15:e568-e580.
    • (2014) Lancet Oncol , vol.15 , pp. e568-e580
    • Warren, G.W.1    Sobus, S.2    Gritz, E.R.3
  • 7
    • 84942907154 scopus 로고    scopus 로고
    • Tobacco cessation may improve lung cancer patient survival
    • Dobson Amato KA, Hyland A, Reed R, et al. Tobacco cessation may improve lung cancer patient survival. J Thorac Oncol. 2015;10:1014-1019.
    • (2015) J Thorac Oncol , vol.10 , pp. 1014-1019
    • Dobson Amato, K.A.1    Hyland, A.2    Reed, R.3
  • 8
    • 84938892410 scopus 로고    scopus 로고
    • An official American Thoracic Society Research statement: Current understanding and future research needs in tobacco control and treatment
    • Leone FT, Carlsen KH, Folan P, et al. An official American Thoracic Society Research statement: current understanding and future research needs in tobacco control and treatment. Am J Respir Crit Care Med. 2015;192:e22-e41.
    • (2015) Am J Respir Crit Care Med , vol.192 , pp. e22-e41
    • Leone, F.T.1    Carlsen, K.H.2    Folan, P.3
  • 9
    • 84969842366 scopus 로고    scopus 로고
    • World Lung Foundation-American Cancer Society. The tobacco atlas Accessed January 22, 2016
    • World Lung Foundation-American Cancer Society. The tobacco atlas. http://www.tobaccoatlas.org/. Accessed January 22, 2016.
  • 10
    • 79961108629 scopus 로고    scopus 로고
    • Reduced lung-cancer mortality with low-dose computed tomographic screening
    • Aberle DR, Adams AM, Berg CD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365:395-409.
    • (2011) N Engl J Med , vol.365 , pp. 395-409
    • Aberle, D.R.1    Adams, A.M.2    Berg, C.D.3
  • 11
    • 84973874708 scopus 로고    scopus 로고
    • The association between smoking abstinence and mortality in the National Lung Screening Trial
    • Tanner NT, Kanodra NM, Gebregziabher M, et al. The association between smoking abstinence and mortality in the National Lung Screening Trial. Am J Respir Crit Care Med. 2016;193:534-541.
    • (2016) Am J Respir Crit Care Med , vol.193 , pp. 534-541
    • Tanner, N.T.1    Kanodra, N.M.2    Gebregziabher, M.3
  • 12
    • 84945283381 scopus 로고    scopus 로고
    • Identifying targeted strategies to improve smoking cessation support for cancer patients
    • Warren GW, Dibaj S, Hutson A, et al. Identifying targeted strategies to improve smoking cessation support for cancer patients. J Thorac Oncol. 2015;10:1532-1537.
    • (2015) J Thorac Oncol , vol.10 , pp. 1532-1537
    • Warren, G.W.1    Dibaj, S.2    Hutson, A.3
  • 13
    • 84960076388 scopus 로고    scopus 로고
    • Integration of tobacco cessation services into multidisciplinary lung cancer care: Rationale, state of the art, and future directions
    • Warren GW, Ward KD. Integration of tobacco cessation services into multidisciplinary lung cancer care: rationale, state of the art, and future directions. Transl Lung Cancer Res. 2015;4:339-352.
    • (2015) Transl Lung Cancer Res , vol.4 , pp. 339-352
    • Warren, G.W.1    Ward, K.D.2
  • 14
    • 84895811460 scopus 로고    scopus 로고
    • Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement
    • Moyer VA. Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014;160:330-338.
    • (2014) Ann Intern Med , vol.160 , pp. 330-338
    • Moyer, V.A.1
  • 15
    • 84858796991 scopus 로고    scopus 로고
    • CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: Status after five annual screening rounds with low-dose CT
    • Saghir Z, Dirksen A, Ashraf H, et al. CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT. Thorax. 2012;67:296-301.
    • (2012) Thorax , vol.67 , pp. 296-301
    • Saghir, Z.1    Dirksen, A.2    Ashraf, H.3
  • 16
    • 69249108174 scopus 로고    scopus 로고
    • A randomized study of lung cancer screening with spiral computed tomography: Three-year results from the DANTE trial
    • Infante M, Cavuto S, Lutman FR, et al. A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial. Am J Respir Crit Care Med. 2009;180:445-453.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 445-453
    • Infante, M.1    Cavuto, S.2    Lutman, F.R.3
  • 17
    • 84859295557 scopus 로고    scopus 로고
    • Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial
    • Pastorino U, Rossi M, Rosato V, et al. Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial. Eur J Cancer Prev. 2012;21:308-315.
    • (2012) Eur J Cancer Prev , vol.21 , pp. 308-315
    • Pastorino, U.1    Rossi, M.2    Rosato, V.3
  • 18
    • 73349107157 scopus 로고    scopus 로고
    • Management of lung nodules detected by volume CT scanning
    • van Klaveren RJ, Oudkerk M, Prokop M, et al. Management of lung nodules detected by volume CT scanning. N Engl J Med. 2009;361:2221-2229.
    • (2009) N Engl J Med , vol.361 , pp. 2221-2229
    • Van Klaveren, R.J.1    Oudkerk, M.2    Prokop, M.3
  • 19
    • 33846564385 scopus 로고    scopus 로고
    • Risk-based selection from the general population in a screening trial: Selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON)
    • van Iersel CA, de Koning HJ, Draisma G, et al. Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON). Int J Cancer. 2007;120:868-874.
    • (2007) Int J Cancer , vol.120 , pp. 868-874
    • Van Iersel, C.A.1    De Koning, H.J.2    Draisma, G.3
  • 20
    • 33751348788 scopus 로고    scopus 로고
    • Nodule management protocol of the NELSON randomised lung cancer screening trial
    • Xu DM, Gietema H, de Koning H, et al. Nodule management protocol of the NELSON randomised lung cancer screening trial. Lung Cancer. 2006;54:177-184.
    • (2006) Lung Cancer , vol.54 , pp. 177-184
    • Xu, D.M.1    Gietema, H.2    De Koning, H.3
  • 21
    • 84874056742 scopus 로고    scopus 로고
    • NELSON lung cancer screening study
    • Spec No A
    • Ru Zhao Y, Xie X, de Koning HJ, et al. NELSON lung cancer screening study. Cancer Imaging. 2011, 11 Spec No A:S79-S84.
    • (2011) Cancer Imaging , vol.11 , pp. S79-S84
    • Ru Zhao, Y.1    Xie, X.2    De Koning, H.J.3
  • 22
    • 84886944999 scopus 로고    scopus 로고
    • Volumetric computed tomography screening for lung cancer: Three rounds of the NELSON trial
    • Horeweg N, van der Aalst CM, Vliegenthart R, et al. Volumetric computed tomography screening for lung cancer: three rounds of the NELSON trial. Eur Respir J. 2013;42:1659-1667.
    • (2013) Eur Respir J , vol.42 , pp. 1659-1667
    • Horeweg, N.1    Van Der Aalst, C.M.2    Vliegenthart, R.3
  • 23
    • 84863229324 scopus 로고    scopus 로고
    • The National Lung Screening Trial: Overview and study design
    • Aberle DR, Berg CD, Black WC, et al. The National Lung Screening Trial: overview and study design. Radiology. 2011;258:243-253.
    • (2011) Radiology , vol.258 , pp. 243-253
    • Aberle, D.R.1    Berg, C.D.2    Black, W.C.3
  • 24
    • 84874009586 scopus 로고    scopus 로고
    • Selection criteria for lung-cancer screening
    • Tammemagi MC, Katki HA, Hocking WG, et al. Selection criteria for lung-cancer screening. N Engl J Med. 2013;368:728-736.
    • (2013) N Engl J Med , vol.368 , pp. 728-736
    • Tammemagi, M.C.1    Katki, H.A.2    Hocking, W.G.3
  • 25
    • 84880560754 scopus 로고    scopus 로고
    • Targeting of low-dose CT screening according to the risk of lung-cancer death
    • Kovalchik SA, Tammemagi M, Berg CD, et al. Targeting of low-dose CT screening according to the risk of lung-cancer death. N Engl J Med. 2013;369:245-254.
    • (2013) N Engl J Med , vol.369 , pp. 245-254
    • Kovalchik, S.A.1    Tammemagi, M.2    Berg, C.D.3
  • 26
    • 84901710470 scopus 로고    scopus 로고
    • Screening for lung cancer using low dose computed tomography
    • Tammemagi MC, Lam S. Screening for lung cancer using low dose computed tomography. BMJ. 2014;348:g2253.
    • (2014) BMJ , vol.348 , pp. g2253
    • Tammemagi, M.C.1    Lam, S.2
  • 27
    • 84555206076 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report
    • Field JK, Smith RA, Aberle DR, et al. International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report. J Thorac Oncol. 2012;7:10-19.
    • (2012) J Thorac Oncol , vol.7 , pp. 10-19
    • Field, J.K.1    Smith, R.A.2    Aberle, D.R.3
  • 28
    • 84924044603 scopus 로고    scopus 로고
    • Application of risk prediction models to lung cancer screening: A review
    • Tammemagi MC. Application of risk prediction models to lung cancer screening: a review. J Thorac Imaging. 2015;30:88-100.
    • (2015) J Thorac Imaging , vol.30 , pp. 88-100
    • Tammemagi, M.C.1
  • 29
    • 79955842511 scopus 로고    scopus 로고
    • Lung cancer risk prediction: Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial models and validation
    • Tammemagi CM, Pinsky PF, Caporaso NE, et al. Lung cancer risk prediction: Prostate, Lung, Colorectal And Ovarian Cancer Screening Trial models and validation. J Natl Cancer Inst. 2011;103:1058-1068.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1058-1068
    • Tammemagi, C.M.1    Pinsky, P.F.2    Caporaso, N.E.3
  • 30
    • 84920973963 scopus 로고    scopus 로고
    • Evaluation of the lung cancer risks at which to screen ever-and never-smokers: Screening rules applied to the PLCO and NLST cohorts
    • Tammemagi MC, Church TR, Hocking WG, et al. Evaluation of the lung cancer risks at which to screen ever-and never-smokers: screening rules applied to the PLCO and NLST cohorts. PLoS Med. 2014;11:e1001764.
    • (2014) PLoS Med , vol.11 , pp. e1001764
    • Tammemagi, M.C.1    Church, T.R.2    Hocking, W.G.3
  • 32
    • 84925870771 scopus 로고    scopus 로고
    • Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada
    • Cressman S, Lam S, Tammemagi MC, et al. Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada. J Thorac Oncol. 2014;9:1449-1458.
    • (2014) J Thorac Oncol , vol.9 , pp. 1449-1458
    • Cressman, S.1    Lam, S.2    Tammemagi, M.C.3
  • 33
    • 84954501899 scopus 로고    scopus 로고
    • Economic Evidence for the Use of Risk-Selection and Risk-Stratification for Lung Cancer Screening Programs
    • Cressman S, Lam S, Tammemägi M, et al. Economic Evidence for the Use of Risk-Selection and Risk-Stratification for Lung Cancer Screening Programs. J Thorac Oncol. 2015;10:S192.
    • (2015) J Thorac Oncol , vol.10 , pp. S192
    • Cressman, S.1    Lam, S.2    Tammemägi, M.3
  • 34
    • 84908587136 scopus 로고    scopus 로고
    • Cost-effectiveness of CT screening in the National Lung Screening Trial
    • Black WC, Gareen IF, Soneji SS, et al. Cost-effectiveness of CT screening in the National Lung Screening Trial. N Engl J Med. 2014;371:1793-1802.
    • (2014) N Engl J Med , vol.371 , pp. 1793-1802
    • Black, W.C.1    Gareen, I.F.2    Soneji, S.S.3
  • 35
    • 84883373200 scopus 로고    scopus 로고
    • Probability of cancer in pulmonary nodules detected on first screening CT
    • McWilliams A, Tammemagi MC, Mayo JR, et al. Probability of cancer in pulmonary nodules detected on first screening CT. N Engl J Med. 2013;369:910-919.
    • (2013) N Engl J Med , vol.369 , pp. 910-919
    • McWilliams, A.1    Tammemagi, M.C.2    Mayo, J.R.3
  • 36
    • 84941425888 scopus 로고    scopus 로고
    • Predictive accuracy of the PanCan lung cancer risk prediction model-external validation based on CT from the Danish Lung Cancer Screening Trial
    • Winkler Wille MM, van Riel SJ, Saghir Z, et al. Predictive accuracy of the PanCan lung cancer risk prediction model-external validation based on CT from the Danish Lung Cancer Screening Trial. Eur Radiol. 2015;25:3093-3099.
    • (2015) Eur Radiol , vol.25 , pp. 3093-3099
    • Winkler Wille, M.M.1    Van Riel, S.J.2    Saghir, Z.3
  • 37
    • 84931561574 scopus 로고    scopus 로고
    • Risk of malignancy in pulmonary nodules: A validation study of four prediction models
    • Al-Ameri A, Malhotra P, Thygesen H, et al. Risk of malignancy in pulmonary nodules: a validation study of four prediction models. Lung Cancer. 2015;89:27-30.
    • (2015) Lung Cancer , vol.89 , pp. 27-30
    • Al-Ameri, A.1    Malhotra, P.2    Thygesen, H.3
  • 38
    • 85027426494 scopus 로고    scopus 로고
    • Lung-RADS versus the McWilliams Nodule Malignancy Score for Risk Prediction: Eevaluation on the Danish Lung Cancer Screening Trial
    • Van Riel SJ, Ciompi F, Wille MW, et al. Lung-RADS versus the McWilliams Nodule Malignancy Score for Risk Prediction: Eevaluation on the Danish Lung Cancer Screening Trial. J Thorac Oncol. 2015;10:S191.
    • (2015) J Thorac Oncol , vol.10 , pp. S191
    • Van Riel, S.J.1    Ciompi, F.2    Wille, M.W.3
  • 39
    • 84969832728 scopus 로고    scopus 로고
    • American College of Radiology. Lung CT Screening Reporting and Data System (Lung-RADS) Accessed January 17, 2016
    • American College of Radiology. Lung CT Screening Reporting and Data System (Lung-RADS). www.acr.org/Quality-Safety/Resources/LungRADS. Accessed January 17, 2016.
  • 40
    • 84940823468 scopus 로고    scopus 로고
    • British Thoracic Society guidelines for the investigation and management of pulmonary nodules
    • Callister ME, Baldwin DR, Akram AR, et al. British Thoracic Society guidelines for the investigation and management of pulmonary nodules. Thorax. 2015;70(suppl 2):ii1-ii54.
    • (2015) Thorax , vol.70 , pp. ii1-ii54
    • Callister, M.E.1    Baldwin, D.R.2    Akram, A.R.3
  • 42
    • 84940100919 scopus 로고    scopus 로고
    • The 2015 World Health Organization Classification of Lung Tumors: Impact of genetic, clinical and radiologic advances since the 2004 classification
    • Travis WD, Brambilla E, Nicholson AG, et al. The 2015 World Health Organization Classification of Lung Tumors: impact of genetic, clinical and radiologic advances since the 2004 classification. J Thorac Oncol. 2015;10:1243-1260.
    • (2015) J Thorac Oncol , vol.10 , pp. 1243-1260
    • Travis, W.D.1    Brambilla, E.2    Nicholson, A.G.3
  • 43
    • 79551563284 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adeno-carcinoma
    • Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adeno-carcinoma. J Thorac Oncol. 2011;6:244-285.
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3
  • 44
    • 84894048269 scopus 로고    scopus 로고
    • Micropapillary and solid subtypes of invasive lung adenocarcinoma: Clinical predictors of histopathology and outcome
    • Cha MJ, Lee HY, Lee KS, et al. Micropapillary and solid subtypes of invasive lung adenocarcinoma: clinical predictors of histopathology and outcome. J Thorac Cardiovasc Surg. 2014;147:921-928 e922.
    • (2014) J Thorac Cardiovasc Surg , vol.147 , pp. 921-928e922
    • Cha, M.J.1    Lee, H.Y.2    Lee, K.S.3
  • 45
    • 84875235174 scopus 로고    scopus 로고
    • Prognostic significance of the IASLC/ATS/ERS classification in Chinese patients - A single institution retrospective study of 292 lung adeno-carcinoma
    • Gu J, Lu C, Guo J, et al. Prognostic significance of the IASLC/ATS/ERS classification in Chinese patients - A single institution retrospective study of 292 lung adeno-carcinoma. J Surg Oncol. 2013;107:474-480.
    • (2013) J Surg Oncol , vol.107 , pp. 474-480
    • Gu, J.1    Lu, C.2    Guo, J.3
  • 46
    • 84888138347 scopus 로고    scopus 로고
    • Prognostic value of the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification on death and recurrence in completely resected stage i lung adenocarcinoma
    • Hung JJ, Jeng WJ, Chou TY, et al. Prognostic value of the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification on death and recurrence in completely resected stage I lung adenocarcinoma. Ann Surg. 2013;258:1079-1086.
    • (2013) Ann Surg , vol.258 , pp. 1079-1086
    • Hung, J.J.1    Jeng, W.J.2    Chou, T.Y.3
  • 47
    • 84905836884 scopus 로고    scopus 로고
    • Predictive value of the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification of Lung Adenocarcinoma in tumor recurrence and patient survival
    • Hung JJ, Yeh YC, Jeng WJ, et al. Predictive value of the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society Classification of Lung Adenocarcinoma in tumor recurrence and patient survival. J Clin Oncol. 2014;32:2357-2364.
    • (2014) J Clin Oncol , vol.32 , pp. 2357-2364
    • Hung, J.J.1    Yeh, Y.C.2    Jeng, W.J.3
  • 48
    • 84897027621 scopus 로고    scopus 로고
    • Prognostic significance of adenocarcinoma in situ, minimally invasive adenocarcinoma, and nonmucinous lepidic predominant invasive adenocarcinoma of the lung in patients with stage i disease
    • Kadota K, Villena-Vargas J, Yoshizawa A, et al. Prognostic significance of adenocarcinoma in situ, minimally invasive adenocarcinoma, and nonmucinous lepidic predominant invasive adenocarcinoma of the lung in patients with stage I disease. Am J Surg Pathol. 2014;38:448-460.
    • (2014) Am J Surg Pathol , vol.38 , pp. 448-460
    • Kadota, K.1    Villena-Vargas, J.2    Yoshizawa, A.3
  • 49
    • 80052264344 scopus 로고    scopus 로고
    • Does lung adenocarcinoma subtype predict patient survival? A clinicopathologic study based on the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary lung adenocarcinoma classification
    • Russell PA, Wainer Z, Wright GM, et al. Does lung adenocarcinoma subtype predict patient survival? A clinicopathologic study based on the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary lung adenocarcinoma classification. J Thorac Oncol. 2011;6:1496-1504.
    • (2011) J Thorac Oncol , vol.6 , pp. 1496-1504
    • Russell, P.A.1    Wainer, Z.2    Wright, G.M.3
  • 50
    • 84885428606 scopus 로고    scopus 로고
    • Prognostic value of the IASLC/ATS/ERS classification in stage i lung adenocar-cinoma patients-based on a hospital study in China
    • Song Z, Zhu H, Guo Z, et al. Prognostic value of the IASLC/ATS/ERS classification in stage I lung adenocar-cinoma patients-based on a hospital study in China. Eur J Surg Oncol. 2013;39:1262-1268.
    • (2013) Eur J Surg Oncol , vol.39 , pp. 1262-1268
    • Song, Z.1    Zhu, H.2    Guo, Z.3
  • 51
    • 84940111611 scopus 로고    scopus 로고
    • Subtype classification of lung adenocarcinoma predicts benefit from adjuvant chemotherapy in patients undergoing complete resection
    • Tsao MS, Marguet S, Le Teuff G, et al. Subtype classification of lung adenocarcinoma predicts benefit from adjuvant chemotherapy in patients undergoing complete resection. J Clin Oncol. 2015;33:3439-3446.
    • (2015) J Clin Oncol , vol.33 , pp. 3439-3446
    • Tsao, M.S.1    Marguet, S.2    Le Teuff, G.3
  • 52
    • 84881662088 scopus 로고    scopus 로고
    • The utility of the proposed IASLC/ATS/ERS lung adenocarcinoma subtypes for disease prognosis and correlation of driver gene alterations
    • Tsuta K, Kawago M, Inoue E, et al. The utility of the proposed IASLC/ATS/ERS lung adenocarcinoma subtypes for disease prognosis and correlation of driver gene alterations. Lung Cancer. 2013;81:371-376.
    • (2013) Lung Cancer , vol.81 , pp. 371-376
    • Tsuta, K.1    Kawago, M.2    Inoue, E.3
  • 53
    • 84964974597 scopus 로고    scopus 로고
    • Solid predominant histologic subtype in resected stage i lung adenocarci-noma is an independent predictor of early, extra-thoracic, multisite recurrence and of poor postrecurrence survival
    • Ujiie H, Kadota K, Chaft JE, et al. Solid predominant histologic subtype in resected stage I lung adenocarci-noma is an independent predictor of early, extra-thoracic, multisite recurrence and of poor postrecurrence survival. J Clin Oncol. 2015;33:2877-2884.
    • (2015) J Clin Oncol , vol.33 , pp. 2877-2884
    • Ujiie, H.1    Kadota, K.2    Chaft, J.E.3
  • 54
    • 84860379332 scopus 로고    scopus 로고
    • The novel histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification system of lung adenocarcinoma is a stage-independent predictor of survival
    • Warth A, Muley T, Meister M, et al. The novel histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification system of lung adenocarcinoma is a stage-independent predictor of survival. J Clin Oncol. 2012;30:1438-1446.
    • (2012) J Clin Oncol , vol.30 , pp. 1438-1446
    • Warth, A.1    Muley, T.2    Meister, M.3
  • 55
    • 84887894876 scopus 로고    scopus 로고
    • The International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society grading system has limited prognostic significance in advanced resected pulmonary adenocarcinoma
    • Westaway DD, Toon CW, Farzin M, et al. The International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society grading system has limited prognostic significance in advanced resected pulmonary adenocarcinoma. Pathology. 2013;45:553-558.
    • (2013) Pathology , vol.45 , pp. 553-558
    • Westaway, D.D.1    Toon, C.W.2    Farzin, M.3
  • 56
    • 84871396304 scopus 로고    scopus 로고
    • Prognostic value of the IASLC/ATS/ERS classification of lung adenocarci-noma in stage i disease of Japanese cases
    • Woo T, Okudela K, Mitsui H, et al. Prognostic value of the IASLC/ATS/ERS classification of lung adenocarci-noma in stage I disease of Japanese cases. Pathol Int. 2012;62:785-791.
    • (2012) Pathol Int , vol.62 , pp. 785-791
    • Woo, T.1    Okudela, K.2    Mitsui, H.3
  • 57
    • 84905584697 scopus 로고    scopus 로고
    • The correlation of the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/Euro-pean Respiratory Society (ERS) classification with prognosis and EGFR mutation in lung adenocarcinoma
    • Yanagawa N, Shiono S, Abiko M, et al. The correlation of the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/Euro-pean Respiratory Society (ERS) classification with prognosis and EGFR mutation in lung adenocarcinoma. Ann Thorac Surg. 2014;98:453-458.
    • (2014) Ann Thorac Surg , vol.98 , pp. 453-458
    • Yanagawa, N.1    Shiono, S.2    Abiko, M.3
  • 58
    • 79955571953 scopus 로고    scopus 로고
    • Impact of proposed IASLC/ATS/ERS classification of lung adenocarci-noma: Prognostic subgroups and implications for further revision of staging based on analysis of 514 stage i cases
    • Yoshizawa A, Motoi N, Riely GJ, et al. Impact of proposed IASLC/ATS/ERS classification of lung adenocarci-noma: prognostic subgroups and implications for further revision of staging based on analysis of 514 stage I cases. Mod Pathol. 2011;24:653-664.
    • (2011) Mod Pathol , vol.24 , pp. 653-664
    • Yoshizawa, A.1    Motoi, N.2    Riely, G.J.3
  • 59
    • 84871969337 scopus 로고    scopus 로고
    • Validation of the IASLC/ATS/ERS lung adenocarcinoma classification for prognosis and association with EGFR and KRAS gene mutations: Analysis of 440 Japanese patients
    • Yoshizawa A, Sumiyoshi S, Sonobe M, et al. Validation of the IASLC/ATS/ERS lung adenocarcinoma classification for prognosis and association with EGFR and KRAS gene mutations: analysis of 440 Japanese patients. J Thorac Oncol. 2013;8:52-61.
    • (2013) J Thorac Oncol , vol.8 , pp. 52-61
    • Yoshizawa, A.1    Sumiyoshi, S.2    Sonobe, M.3
  • 60
    • 84883414922 scopus 로고    scopus 로고
    • Why do pathological stage IA lung adenocarcinomas vary from prognosis? a clini-copathologic study of 176 patients with pathological stage IA lung adenocarcinoma based on the IASLC/ATS/ERS classification
    • Zhang J, Wu J, Tan Q, et al. Why do pathological stage IA lung adenocarcinomas vary from prognosis? a clini-copathologic study of 176 patients with pathological stage IA lung adenocarcinoma based on the IASLC/ATS/ERS classification. J Thorac Oncol. 2013;8:1196-1202.
    • (2013) J Thorac Oncol , vol.8 , pp. 1196-1202
    • Zhang, J.1    Wu, J.2    Tan, Q.3
  • 61
    • 84946920704 scopus 로고    scopus 로고
    • The prognostic and predictive value of solid subtype in invasive lung adeno-carcinoma
    • Zhang Y, Li J, Wang R, et al. The prognostic and predictive value of solid subtype in invasive lung adeno-carcinoma. Sci Rep. 2014;4:7163.
    • (2014) Sci Rep , vol.4 , pp. 7163
    • Zhang, Y.1    Li, J.2    Wang, R.3
  • 62
    • 84938286585 scopus 로고    scopus 로고
    • Tumor spread through air spaces is an important pattern of invasion and impacts the frequency and location of recurrences after limited resection for small stage i lung adenocar-cinomas
    • Kadota K, Nitadori J, Sima CS, et al. Tumor spread through air spaces is an important pattern of invasion and impacts the frequency and location of recurrences after limited resection for small stage I lung adenocar-cinomas. J Thorac Oncol. 2015;10:806-814.
    • (2015) J Thorac Oncol , vol.10 , pp. 806-814
    • Kadota, K.1    Nitadori, J.2    Sima, C.S.3
  • 63
    • 84956629466 scopus 로고    scopus 로고
    • Tumor islands and spread through air spaces: Distinct patterns of invasion in lung adenocarcinoma
    • Morales-Oyarvide V, Mino-Kenudson M. Tumor islands and spread through air spaces: distinct patterns of invasion in lung adenocarcinoma. Pathol Int. 2016;66:1-7.
    • (2016) Pathol Int , vol.66 , pp. 1-7
    • Morales-Oyarvide, V.1    Mino-Kenudson, M.2
  • 64
    • 84883185369 scopus 로고    scopus 로고
    • Impact of micropapillary histologic subtype in selecting limited resection vs lobectomy for lung adenocarcinoma of 2cm or smaller
    • Nitadori J, Bograd AJ, Kadota K, et al. Impact of micropapillary histologic subtype in selecting limited resection vs lobectomy for lung adenocarcinoma of 2cm or smaller. J Natl Cancer Inst. 2013;105:1212-1220.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1212-1220
    • Nitadori, J.1    Bograd, A.J.2    Kadota, K.3
  • 65
    • 84872858767 scopus 로고    scopus 로고
    • Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis
    • Onozato ML, Kovach AE, Yeap BY, et al. Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis. Am J Surg Pathol. 2013;37:287-294.
    • (2013) Am J Surg Pathol , vol.37 , pp. 287-294
    • Onozato, M.L.1    Kovach, A.E.2    Yeap, B.Y.3
  • 66
    • 84929907783 scopus 로고    scopus 로고
    • Prognostic impact of intra-alveolar tumor spread in pulmonary adenocarcinoma
    • Warth A, Muley T, Kossakowski CA, et al. Prognostic impact of intra-alveolar tumor spread in pulmonary adenocarcinoma. Am J Surg Pathol. 2015;39:793-801.
    • (2015) Am J Surg Pathol , vol.39 , pp. 793-801
    • Warth, A.1    Muley, T.2    Kossakowski, C.A.3
  • 67
    • 84938419571 scopus 로고    scopus 로고
    • Accuracy of the IASLC/ATS/ERS histological subtyping of stage i lung adenocarcinoma on intraoperative frozen sections
    • Trejo Bittar HE, Incharoen P, Althouse AD, et al. Accuracy of the IASLC/ATS/ERS histological subtyping of stage I lung adenocarcinoma on intraoperative frozen sections. Mod Pathol. 2015;28:1058-1063.
    • (2015) Mod Pathol , vol.28 , pp. 1058-1063
    • Trejo Bittar, H.E.1    Incharoen, P.2    Althouse, A.D.3
  • 68
    • 84958639055 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification predicts occult lymph node metastasis in clinically mediastinal node-negative lung adenocarcinoma
    • Yeh YC, Kadota K, Nitadori J, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification predicts occult lymph node metastasis in clinically mediastinal node-negative lung adenocarcinoma. Eur J Cardiothorac Surg. 2016;49:e9-e15.
    • (2016) Eur J Cardiothorac Surg , vol.49 , pp. e9-e15
    • Yeh, Y.C.1    Kadota, K.2    Nitadori, J.3
  • 69
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014;511:543-550.
    • (2014) Nature , vol.511 , pp. 543-550
  • 70
    • 84866894408 scopus 로고    scopus 로고
    • Comprehensive genomic characterization of squamous cell lung cancers
    • Cancer Genome Atlas Research Network. Comprehensive genomic characterization of squamous cell lung cancers. Nature. 2012;489:519-525.
    • (2012) Nature , vol.489 , pp. 519-525
  • 71
    • 84890046280 scopus 로고    scopus 로고
    • A genomics-based classification of human lung tumors
    • Clinical Lung Cancer Genome Project, Network Genomic Medicine. A genomics-based classification of human lung tumors. Sci Transl Med. 2013;5:209ra153.
    • (2013) Sci Transl Med , vol.5 , pp. 209ra153
  • 72
    • 84902284546 scopus 로고    scopus 로고
    • Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids
    • Fernandez-Cuesta L, Peifer M, Lu X, et al. Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids. Nat Commun. 2014;5:3518.
    • (2014) Nat Commun , vol.5 , pp. 3518
    • Fernandez-Cuesta, L.1    Peifer, M.2    Lu, X.3
  • 73
    • 84938132350 scopus 로고    scopus 로고
    • Comprehensive genomic profiles of small cell lung cancer
    • George J, Lim JS, Jang SJ, et al. Comprehensive genomic profiles of small cell lung cancer. Nature. 2015;524:47-53.
    • (2015) Nature , vol.524 , pp. 47-53
    • George, J.1    Lim, J.S.2    Jang, S.J.3
  • 74
    • 84866434919 scopus 로고    scopus 로고
    • Genomic landscape of non-small cell lung cancer in smokers and never-smokers
    • Govindan R, Ding L, Griffith M, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell. 2012;150:1121-1134.
    • (2012) Cell , vol.150 , pp. 1121-1134
    • Govindan, R.1    Ding, L.2    Griffith, M.3
  • 75
    • 84866410479 scopus 로고    scopus 로고
    • Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
    • Imielinski M, Berger AH, Hammerman PS, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 2012;150:1107-1120.
    • (2012) Cell , vol.150 , pp. 1107-1120
    • Imielinski, M.1    Berger, A.H.2    Hammerman, P.S.3
  • 76
    • 84897018525 scopus 로고    scopus 로고
    • Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients
    • Kim Y, Hammerman PS, Kim J, et al. Integrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients. J Clin Oncol. 2014;32:121-128.
    • (2014) J Clin Oncol , vol.32 , pp. 121-128
    • Kim, Y.1    Hammerman, P.S.2    Kim, J.3
  • 77
    • 84866851740 scopus 로고    scopus 로고
    • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
    • Peifer M, Fernandez-Cuesta L, Sos ML, et al. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nat Genet. 2012;44:1104-1110.
    • (2012) Nat Genet , vol.44 , pp. 1104-1110
    • Peifer, M.1    Fernandez-Cuesta, L.2    Sos, M.L.3
  • 78
    • 84866849548 scopus 로고    scopus 로고
    • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
    • Rudin CM, Durinck S, Stawiski EW, et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet. 2012;44:1111-1116.
    • (2012) Nat Genet , vol.44 , pp. 1111-1116
    • Rudin, C.M.1    Durinck, S.2    Stawiski, E.W.3
  • 79
    • 84900829967 scopus 로고    scopus 로고
    • Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
    • Kris MG, Johnson BE, Berry LD, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA. 2014;311:1998-2006.
    • (2014) JAMA , vol.311 , pp. 1998-2006
    • Kris, M.G.1    Johnson, B.E.2    Berry, L.D.3
  • 80
    • 84946563770 scopus 로고    scopus 로고
    • Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients
    • Wang R, Zhang Y, Pan Y, et al. Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients. Oncotarget. 2015;6:34300-34308.
    • (2015) Oncotarget , vol.6 , pp. 34300-34308
    • Wang, R.1    Zhang, Y.2    Pan, Y.3
  • 81
    • 84960496176 scopus 로고    scopus 로고
    • Management of advanced non-small cell lung cancers with known mutations or rearrangements: Latest evidence and treatment approaches
    • Shea M, Costa DB, Rangachari D. Management of advanced non-small cell lung cancers with known mutations or rearrangements: latest evidence and treatment approaches. Ther Adv Respir Dis. 2016;10:113-129.
    • (2016) Ther Adv Respir Dis , vol.10 , pp. 113-129
    • Shea, M.1    Costa, D.B.2    Rangachari, D.3
  • 82
    • 84925773492 scopus 로고    scopus 로고
    • The IASLC lung cancer staging project: The new database to inform the eighth edition of the TNM classification of lung cancer
    • Rami-Porta R, Bolejack V, Giroux DJ, et al. The IASLC lung cancer staging project: the new database to inform the eighth edition of the TNM classification of lung cancer. J Thorac Oncol. 2014;9:1618-1624.
    • (2014) J Thorac Oncol , vol.9 , pp. 1618-1624
    • Rami-Porta, R.1    Bolejack, V.2    Giroux, D.J.3
  • 83
    • 84947909552 scopus 로고    scopus 로고
    • The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the revision of the N descriptors in the forthcoming 8th edition of the TNM classification for lung cancer
    • Asamura H, Chansky K, Crowley J, et al. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: proposals for the revision of the N descriptors in the forthcoming 8th edition of the TNM classification for lung cancer. J Thorac Oncol. 2015;10: 1675-1684.
    • (2015) J Thorac Oncol , vol.10 , pp. 1675-1684
    • Asamura, H.1    Chansky, K.2    Crowley, J.3
  • 84
    • 84945255444 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: Proposals for the revision of the M descriptors in the forthcoming eighth edition of the TNM classification of lung cancer
    • Eberhardt WE, Mitchell A, Crowley J, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the M descriptors in the forthcoming eighth edition of the TNM classification of lung cancer. J Thorac Oncol. 2015;10:1515-1522.
    • (2015) J Thorac Oncol , vol.10 , pp. 1515-1522
    • Eberhardt, W.E.1    Mitchell, A.2    Crowley, J.3
  • 85
    • 84942853428 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: Proposals for the revisions of the T descriptors in the forthcoming eighth edition of the TNM classification for lung cancer
    • Rami-Porta R, Bolejack V, Crowley J, et al. The IASLC Lung Cancer Staging Project: proposals for the revisions of the T descriptors in the forthcoming eighth edition of the TNM classification for lung cancer. J Thorac Oncol. 2015;10:990-1003.
    • (2015) J Thorac Oncol , vol.10 , pp. 990-1003
    • Rami-Porta, R.1    Bolejack, V.2    Crowley, J.3
  • 86
    • 84959324583 scopus 로고    scopus 로고
    • The IASLC Lung Cancer Staging Project: Proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung cancer
    • Goldstraw P, Chansky K, Crowley J, et al. The IASLC Lung Cancer Staging Project: proposals for revision of the TNM stage groupings in the forthcoming (eighth) edition of the TNM classification for lung cancer. J Thorac Oncol. 2016;11:39-51.
    • (2016) J Thorac Oncol , vol.11 , pp. 39-51
    • Goldstraw, P.1    Chansky, K.2    Crowley, J.3
  • 87
    • 84962585133 scopus 로고    scopus 로고
    • The International Association for the Study of Lung Cancer Lung Cancer Staging Project: Proposals for the revision of the clinical and pathologic staging of small cell lung cancer in the forthcoming eighth edition of the TNM classification for lung cancer
    • Nicholson AG, Chansky K, Crowley J, et al. The International Association for the Study of Lung Cancer Lung Cancer Staging Project: proposals for the revision of the clinical and pathologic staging of small cell lung cancer in the forthcoming eighth edition of the TNM classification for lung cancer. J Thorac Oncol. 2016;11: 300-311.
    • (2016) J Thorac Oncol , vol.11 , pp. 300-311
    • Nicholson, A.G.1    Chansky, K.2    Crowley, J.3
  • 88
    • 20444378930 scopus 로고    scopus 로고
    • Complete resection in lung cancer surgery: Proposed definition
    • Rami-Porta R, Wittekind C, Goldstraw P. Complete resection in lung cancer surgery: proposed definition. Lung Cancer. 2005;49:25-33.
    • (2005) Lung Cancer , vol.49 , pp. 25-33
    • Rami-Porta, R.1    Wittekind, C.2    Goldstraw, P.3
  • 89
    • 84879162188 scopus 로고    scopus 로고
    • Radiographically determined noninvasive adenocarcinoma of the lung: Survival outcomes of Japan Clinical Oncology Group 0201
    • Asamura H, Hishida T, Suzuki K, et al. Radiographically determined noninvasive adenocarcinoma of the lung: survival outcomes of Japan Clinical Oncology Group 0201. J Thorac Cardiovasc Surg. 2013;146:24-30.
    • (2013) J Thorac Cardiovasc Surg , vol.146 , pp. 24-30
    • Asamura, H.1    Hishida, T.2    Suzuki, K.3
  • 90
    • 84868357354 scopus 로고    scopus 로고
    • Clinical controlled comparison between lobectomy and segmental resection for patients over 70 years of age with clinical stage i non-small cell lung cancer
    • Cheng YD, Duan CJ, Dong S, et al. Clinical controlled comparison between lobectomy and segmental resection for patients over 70 years of age with clinical stage I non-small cell lung cancer. Eur J Surg Oncol. 2012;38:1149-1155.
    • (2012) Eur J Surg Oncol , vol.38 , pp. 1149-1155
    • Cheng, Y.D.1    Duan, C.J.2    Dong, S.3
  • 91
    • 84903727209 scopus 로고    scopus 로고
    • Management of elderly patients with NSCLC; Updated expert's opinion paper: EORTC Elderly Task Force Lung Cancer Group and International Society for Geriatric Oncology
    • Pallis AG, Gridelli C, Wedding U, et al. Management of elderly patients with NSCLC; updated expert's opinion paper: EORTC Elderly Task Force, Lung Cancer Group and International Society for Geriatric Oncology. Ann Oncol. 2014;25:1270-1283.
    • (2014) Ann Oncol , vol.25 , pp. 1270-1283
    • Pallis, A.G.1    Gridelli, C.2    Wedding, U.3
  • 92
    • 79955584277 scopus 로고    scopus 로고
    • Surgical treatment of lung cancer in the octogenarians: Results of a nationwide audit
    • Rivera C, Dahan M, Bernard A, et al. Surgical treatment of lung cancer in the octogenarians: results of a nationwide audit. Eur J Cardiothorac Surg. 2011;39:981-986.
    • (2011) Eur J Cardiothorac Surg , vol.39 , pp. 981-986
    • Rivera, C.1    Dahan, M.2    Bernard, A.3
  • 93
    • 84969870156 scopus 로고    scopus 로고
    • Treatment of elderly and high risk patients with localized NSCLC [abstract]
    • ED06.03
    • Weyant MJ. Treatment of elderly and high risk patients with localized NSCLC [abstract]. J Thorac Oncol. 2015;10(suppl): ED06.03.
    • (2015) J Thorac Oncol , vol.10
    • Weyant, M.J.1
  • 94
    • 84940188079 scopus 로고    scopus 로고
    • Video-assisted versus open lo-bectomy in patients with compromised lung function: A literature review and meta-analysis
    • Zhang R, Ferguson MK. Video-assisted versus open lo-bectomy in patients with compromised lung function: a literature review and meta-analysis. PLoS One. 2015;10:e0124512.
    • (2015) PLoS One , vol.10 , pp. e0124512
    • Zhang, R.1    Ferguson, M.K.2
  • 95
    • 33746036502 scopus 로고    scopus 로고
    • Outcomes of sublobar resection versus lobectomy for stage i non-small cell lung cancer: A 13-year analysis
    • [discussion: 415-406]
    • El-Sherif A, Gooding WE, Santos R, et al. Outcomes of sublobar resection versus lobectomy for stage I non-small cell lung cancer: a 13-year analysis. Ann Thorac Surg. 2006;82:408-415 [discussion: 415-406].
    • (2006) Ann Thorac Surg , vol.82 , pp. 408-415
    • El-Sherif, A.1    Gooding, W.E.2    Santos, R.3
  • 96
    • 77950345964 scopus 로고    scopus 로고
    • A phase III randomized trial of lobectomy versus limited resection for small sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L)
    • Nakamura K, Saji H, Nakajima R, et al. A phase III randomized trial of lobectomy versus limited resection for small sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L). Jpn J Clin Oncol. 2010;40:271-274.
    • (2010) Jpn J Clin Oncol , vol.40 , pp. 271-274
    • Nakamura, K.1    Saji, H.2    Nakajima, R.3
  • 97
    • 84905845245 scopus 로고    scopus 로고
    • Role of limited sublobar resection for early-stage lung cancer: Steady progress
    • Asamura H. Role of limited sublobar resection for early-stage lung cancer: steady progress. J Clin Oncol. 2014;32:2403-2404.
    • (2014) J Clin Oncol , vol.32 , pp. 2403-2404
    • Asamura, H.1
  • 98
    • 85027426206 scopus 로고    scopus 로고
    • Rationale for sublobar resection for early cancer
    • Asamura H. Rationale for sublobar resection for early cancer. J Thorac Oncol. 2015;10:S106.
    • (2015) J Thorac Oncol , vol.10 , pp. S106
    • Asamura, H.1
  • 99
    • 79953008658 scopus 로고    scopus 로고
    • Combined use of positron emission tomography and volume doubling time in lung cancer screening with low-dose CT scanning
    • Ashraf H, Dirksen A, Loft A, et al. Combined use of positron emission tomography and volume doubling time in lung cancer screening with low-dose CT scanning. Thorax. 2011;66:315-319.
    • (2011) Thorax , vol.66 , pp. 315-319
    • Ashraf, H.1    Dirksen, A.2    Loft, A.3
  • 100
    • 33750315764 scopus 로고    scopus 로고
    • Survival of patients with stage i lung cancer detected on CT screening
    • Henschke CI, Yankelevitz DF, Libby DM, et al. Survival of patients with stage I lung cancer detected on CT screening. N Engl J Med. 2006;355:1763-1771.
    • (2006) N Engl J Med , vol.355 , pp. 1763-1771
    • Henschke, C.I.1    Yankelevitz, D.F.2    Libby, D.M.3
  • 101
    • 85027426275 scopus 로고    scopus 로고
    • Role of PET scan in workup of nodules
    • Pastorino U. Role of PET scan in workup of nodules. J Thorac Oncol. 2015;10:S133.
    • (2015) J Thorac Oncol , vol.10 , pp. S133
    • Pastorino, U.1
  • 102
    • 84856694120 scopus 로고    scopus 로고
    • Surgical implications of the new IASLC/ATS/ERS adenocarcinoma classification
    • Van Schil PE, Asamura H, Rusch VW, et al. Surgical implications of the new IASLC/ATS/ERS adenocarcinoma classification. Eur Respir J. 2012;39:478-486.
    • (2012) Eur Respir J , vol.39 , pp. 478-486
    • Van Schil, P.E.1    Asamura, H.2    Rusch, V.W.3
  • 103
    • 85027426410 scopus 로고    scopus 로고
    • When to intervene on screening detected lung nodules
    • Veronesi G. When to intervene on screening detected lung nodules. J Thorac Oncol. 2015;10:S105.
    • (2015) J Thorac Oncol , vol.10 , pp. S105
    • Veronesi, G.1
  • 104
    • 84870525789 scopus 로고    scopus 로고
    • Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: A cohort study
    • Veronesi G, Maisonneuve P, Bellomi M, et al. Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: a cohort study. Ann Intern Med. 2012;157:776-784.
    • (2012) Ann Intern Med , vol.157 , pp. 776-784
    • Veronesi, G.1    Maisonneuve, P.2    Bellomi, M.3
  • 105
    • 79951767684 scopus 로고    scopus 로고
    • Screening-detected lung cancers: Is systematic nodal dissection always essential?
    • Veronesi G, Maisonneuve P, Pelosi G, et al. Screening-detected lung cancers: is systematic nodal dissection always essential? J Thorac Oncol. 2011;6:525-530.
    • (2011) J Thorac Oncol , vol.6 , pp. 525-530
    • Veronesi, G.1    Maisonneuve, P.2    Pelosi, G.3
  • 106
    • 84902533480 scopus 로고    scopus 로고
    • Diagnostic performance of low-dose computed tomography screening for lung cancer over five years
    • Veronesi G, Maisonneuve P, Spaggiari L, et al. Diagnostic performance of low-dose computed tomography screening for lung cancer over five years. J Thorac Oncol. 2014;9:935-939.
    • (2014) J Thorac Oncol , vol.9 , pp. 935-939
    • Veronesi, G.1    Maisonneuve, P.2    Spaggiari, L.3
  • 107
    • 84961290492 scopus 로고    scopus 로고
    • Positron emission tomography in the diagnostic work-up of screening-detected lung nodules
    • Veronesi G, Travaini LL, Maisonneuve P, et al. Positron emission tomography in the diagnostic work-up of screening-detected lung nodules. Eur Respir J. 2015;45:501-510.
    • (2015) Eur Respir J , vol.45 , pp. 501-510
    • Veronesi, G.1    Travaini, L.L.2    Maisonneuve, P.3
  • 108
    • 84939623045 scopus 로고    scopus 로고
    • CT Screening for lung cancer: Nonsolid nodules in baseline and annual repeat rounds
    • Yankelevitz DF, Yip R, Smith JP, et al. CT Screening for lung cancer: nonsolid nodules in baseline and annual repeat rounds. Radiology. 2015;277:555-564.
    • (2015) Radiology , vol.277 , pp. 555-564
    • Yankelevitz, D.F.1    Yip, R.2    Smith, J.P.3
  • 109
    • 84940476819 scopus 로고    scopus 로고
    • Neoadjuvant chemo-radiation and surgery improves survival outcomes compared with definitive chemoradiation in the treatment of stage IIIA N2 non-small-cell lung cancer
    • [discussion: 690]
    • Darling GE, Li F, Patsios D, et al. Neoadjuvant chemo-radiation and surgery improves survival outcomes compared with definitive chemoradiation in the treatment of stage IIIA N2 non-small-cell lung cancer. Eur J Cardiothorac Surg. 2015;48:684-690 [discussion: 690].
    • (2015) Eur J Cardiothorac Surg , vol.48 , pp. 684-690
    • Darling, G.E.1    Li, F.2    Patsios, D.3
  • 110
    • 84923171733 scopus 로고    scopus 로고
    • Concurrent chemoradiotherapy in stage III non-small-cell lung cancer: What is the best regimen?
    • Eberhardt WE. Concurrent chemoradiotherapy in stage III non-small-cell lung cancer: what is the best regimen? J Clin Oncol. 2015;33:532-533.
    • (2015) J Clin Oncol , vol.33 , pp. 532-533
    • Eberhardt, W.E.1
  • 111
    • 84941599354 scopus 로고    scopus 로고
    • 2nd ESMO Consensus Conference in Lung Cancer: Locally advanced stage III non-small-cell lung cancer
    • Eberhardt WE, De Ruysscher D, Weder W, et al. 2nd ESMO Consensus Conference in Lung Cancer: locally advanced stage III non-small-cell lung cancer. Ann Oncol. 2015;26:1573-1588.
    • (2015) Ann Oncol , vol.26 , pp. 1573-1588
    • Eberhardt, W.E.1    De Ruysscher, D.2    Weder, W.3
  • 112
    • 84957453635 scopus 로고    scopus 로고
    • Phase III study of surgery versus definitive concurrent chemo-radiotherapy boost in patients with resectable stage IIIA (N2) and selected IIIB non-small-cell lung cancer after induction chemotherapy and concurrent chemo-radiotherapy (ESPATUE)
    • Eberhardt WE, Pottgen C, Gauler TC, et al. Phase III study of surgery versus definitive concurrent chemo-radiotherapy boost in patients with resectable stage IIIA (N2) and selected IIIB non-small-cell lung cancer after induction chemotherapy and concurrent chemo-radiotherapy (ESPATUE). J Clin Oncol. 2015;33:4194-4201.
    • (2015) J Clin Oncol , vol.33 , pp. 4194-4201
    • Eberhardt, W.E.1    Pottgen, C.2    Gauler, T.C.3
  • 113
    • 84941599195 scopus 로고    scopus 로고
    • Multimodal treatment of non-small-cell lung cancer
    • Eberhardt WE, Stuschke M. Multimodal treatment of non-small-cell lung cancer. Lancet. 2015;386:1018-1020.
    • (2015) Lancet , vol.386 , pp. 1018-1020
    • Eberhardt, W.E.1    Stuschke, M.2
  • 114
    • 84876128935 scopus 로고    scopus 로고
    • Radical treatment of non-small cell lung cancer during the last 5 years
    • McCloskey P, Balduyck B, Van Schil PE, et al. Radical treatment of non-small cell lung cancer during the last 5 years. Eur J Cancer. 2013;49:1555-1564.
    • (2013) Eur J Cancer , vol.49 , pp. 1555-1564
    • McCloskey, P.1    Balduyck, B.2    Van Schil, P.E.3
  • 115
    • 84940832301 scopus 로고    scopus 로고
    • Outcome of surgery versus radiotherapy after induction treatment in patients with N2 disease: Systematic review and meta-analysis of randomised trials
    • McElnay PJ, Choong A, Jordan E, et al. Outcome of surgery versus radiotherapy after induction treatment in patients with N2 disease: systematic review and meta-analysis of randomised trials. Thorax. 2015;70:764-768.
    • (2015) Thorax , vol.70 , pp. 764-768
    • McElnay, P.J.1    Choong, A.2    Jordan, E.3
  • 116
    • 84941600372 scopus 로고    scopus 로고
    • Induction chemo-radiation in stage IIIA/N2 non-small-cell lung cancer: A phase 3 randomised trial
    • Pless M, Stupp R, Ris HB, et al. Induction chemo-radiation in stage IIIA/N2 non-small-cell lung cancer: a phase 3 randomised trial. Lancet. 2015;386:1049-1056.
    • (2015) Lancet , vol.386 , pp. 1049-1056
    • Pless, M.1    Stupp, R.2    Ris, H.B.3
  • 118
    • 0036838163 scopus 로고    scopus 로고
    • A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasis
    • Downey RJ, Ng KK, Kris MG, et al. A phase II trial of chemotherapy and surgery for non-small cell lung cancer patients with a synchronous solitary metastasis. Lung Cancer. 2002;38:193-197.
    • (2002) Lung Cancer , vol.38 , pp. 193-197
    • Downey, R.J.1    Ng, K.K.2    Kris, M.G.3
  • 119
    • 61449325290 scopus 로고    scopus 로고
    • Surgery for oligometastatic disease in non-small-cell lung cancer
    • Van Schil PE, Hendriks JM, Carp L, et al. Surgery for oligometastatic disease in non-small-cell lung cancer. Expert Rev Anticancer Ther. 2008;8:1931-1938.
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 1931-1938
    • Van Schil, P.E.1    Hendriks, J.M.2    Carp, L.3
  • 120
    • 0346238665 scopus 로고    scopus 로고
    • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer
    • Arriagada R, Bergman B, Dunant A, et al. Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. N Engl J Med. 2004;350:351-360.
    • (2004) N Engl J Med , vol.350 , pp. 351-360
    • Arriagada, R.1    Bergman, B.2    Dunant, A.3
  • 121
    • 33747847740 scopus 로고    scopus 로고
    • Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): A randomised controlled trial
    • Douillard JY, Rosell R, De Lena M, et al. Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomised controlled trial. Lancet Oncol. 2006;7:719-727.
    • (2006) Lancet Oncol , vol.7 , pp. 719-727
    • Douillard, J.Y.1    Rosell, R.2    De Lena, M.3
  • 122
    • 49049109683 scopus 로고    scopus 로고
    • Lung adjuvant cisplatin evaluation: A pooled analysis by the LACE Collaborative Group
    • Pignon JP, Tribodet H, Scagliotti GV, et al. Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group. J Clin Oncol. 2008;26:3552-3559.
    • (2008) J Clin Oncol , vol.26 , pp. 3552-3559
    • Pignon, J.P.1    Tribodet, H.2    Scagliotti, G.V.3
  • 123
    • 20544455590 scopus 로고    scopus 로고
    • Vinorelbine plus cisplatin vs. Observation in resected non-small-cell lung cancer
    • Winton T, Livingston R, Johnson D, et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med. 2005;352:2589-2597.
    • (2005) N Engl J Med , vol.352 , pp. 2589-2597
    • Winton, T.1    Livingston, R.2    Johnson, D.3
  • 124
    • 84969768087 scopus 로고    scopus 로고
    • Randomized phase III trial of adjuvant chemotherapy with or without bevacizumab in resected non-small cell lung cancer (NSCLC): Results of E1505
    • Wakelee HA, Dahlberg SE, Keller SM, et al. Randomized phase III trial of adjuvant chemotherapy with or without bevacizumab in resected non-small cell lung cancer (NSCLC): results of E1505. J Thorac Oncol. 2015;10:S796.
    • (2015) J Thorac Oncol , vol.10 , pp. S796
    • Wakelee, H.A.1    Dahlberg, S.E.2    Keller, S.M.3
  • 125
    • 84948384227 scopus 로고    scopus 로고
    • Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non-small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial
    • Kelly K, Altorki NK, Eberhardt WE, et al. Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non-small-cell lung cancer (RADIANT): a randomized, double-blind, phase III trial. J Clin Oncol. 2015;33: 4007-4014.
    • (2015) J Clin Oncol , vol.33 , pp. 4007-4014
    • Kelly, K.1    Altorki, N.K.2    Eberhardt, W.E.3
  • 126
    • 33748435058 scopus 로고    scopus 로고
    • DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
    • Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med. 2006;355: 983-991.
    • (2006) N Engl J Med , vol.355 , pp. 983-991
    • Olaussen, K.A.1    Dunant, A.2    Fouret, P.3
  • 127
    • 84969836971 scopus 로고    scopus 로고
    • Randomized phase III trial of customized adjuvant chemotherapy (CT) according BRCA-1 expression levels in patients with node positive resected non-small cell lung cancer (NSCLS) SCAT: A Spanish Lung Cancer Group trial (Eudract:2007-000067-15; NCTgov: 00478699) [abstract]
    • Massuti B, Cobo M, Rodriguez-Paniagua JM, et al. Randomized phase III trial of customized adjuvant chemotherapy (CT) according BRCA-1 expression levels in patients with node positive resected non-small cell lung cancer (NSCLS) SCAT: A Spanish Lung Cancer Group trial (Eudract:2007-000067-15; NCTgov: 00478699) [abstract]. J Clin Oncol. 2015;33(suppl):7507.
    • (2015) J Clin Oncol , vol.33 , pp. 7507
    • Massuti, B.1    Cobo, M.2    Rodriguez-Paniagua, J.M.3
  • 128
    • 84904797670 scopus 로고    scopus 로고
    • Customized adjuvant phase II trial in patients with non-small-cell lung cancer: IFCT-0801 TASTE
    • Wislez M, Barlesi F, Besse B, et al. Customized adjuvant phase II trial in patients with non-small-cell lung cancer: IFCT-0801 TASTE. J Clin Oncol. 2014;32:1256-1261.
    • (2014) J Clin Oncol , vol.32 , pp. 1256-1261
    • Wislez, M.1    Barlesi, F.2    Besse, B.3
  • 129
    • 84922365301 scopus 로고    scopus 로고
    • 1173OMA-GRIT, a double-blind, randomized, placebo-controlled phase III study to assess the efficacy of the recMAGE-A3 + AS15 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small cell lung cancer (NSCLC)
    • Vansteenkiste JF, Cho B, Vanakesa T, et al. 1173OMA-GRIT, a double-blind, randomized, placebo-controlled phase III study to assess the efficacy of the recMAGE-A3 + AS15 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small cell lung cancer (NSCLC). Ann Oncol. 2014;25:iv409.
    • (2014) Ann Oncol , vol.25 , pp. iv409
    • Vansteenkiste, J.F.1    Cho, B.2    Vanakesa, T.3
  • 130
    • 84969798511 scopus 로고    scopus 로고
    • Update on phase III clinical trial of investigational MAGE-A3 antigen-specific cancer immunotherapeutic in non-small cell lung cancer [news release]. London, UK: GlaxoSmithKline; April 2, 2014 Accessed March 10, 2016
    • Update on phase III clinical trial of investigational MAGE-A3 antigen-specific cancer immunotherapeutic in non-small cell lung cancer [news release]. London, UK: GlaxoSmithKline; April 2, 2014. https://us.gsk.com/en-us/media/press-releases/2014/update-on-phase-iii-clinical-trial-of-investigational-mage-a3-antigen-specific-cancer-immunotherapeutic-in-non-small-cell-lung-cancer/. Accessed March 10, 2016.
  • 131
    • 77949520655 scopus 로고    scopus 로고
    • Stereotactic body radiation therapy for inoperable early stage lung cancer
    • Timmerman R, Paulus R, Galvin J, et al. Stereotactic body radiation therapy for inoperable early stage lung cancer. JAMA. 2010;303:1070-1076.
    • (2010) JAMA , vol.303 , pp. 1070-1076
    • Timmerman, R.1    Paulus, R.2    Galvin, J.3
  • 132
    • 84930272308 scopus 로고    scopus 로고
    • Stereotactic ablative radiotherapy versus lobectomy for operable stage i non-small-cell lung cancer: A pooled analysis of two randomised trials
    • Chang JY, Senan S, Paul MA, et al. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015;16:630-637.
    • (2015) Lancet Oncol , vol.16 , pp. 630-637
    • Chang, J.Y.1    Senan, S.2    Ma, P.3
  • 133
    • 84926419322 scopus 로고    scopus 로고
    • Video-assisted thor-acoscopic lobectomy versus stereotactic radiotherapy for stage i lung cancer
    • Hamaji M, Chen F, Matsuo Y, et al. Video-assisted thor-acoscopic lobectomy versus stereotactic radiotherapy for stage I lung cancer. Ann Thorac Surg. 2015;99: 1122-1129.
    • (2015) Ann Thorac Surg , vol.99 , pp. 1122-1129
    • Hamaji, M.1    Chen, F.2    Matsuo, Y.3
  • 134
    • 84922481377 scopus 로고    scopus 로고
    • Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage i non-small-cell lung cancer in patients at high risk for lo-bectomy: A propensity score matching analysis
    • Matsuo Y, Chen F, Hamaji M, et al. Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage I non-small-cell lung cancer in patients at high risk for lo-bectomy: a propensity score matching analysis. Eur J Cancer. 2014;50:2932-2938.
    • (2014) Eur J Cancer , vol.50 , pp. 2932-2938
    • Matsuo, Y.1    Chen, F.2    Hamaji, M.3
  • 135
    • 85027426079 scopus 로고    scopus 로고
    • Surgery vs. SBRT in operable NSCLC-surgery
    • Van Schil P. Surgery vs. SBRT in operable NSCLC-surgery. J Thorac Oncol. 2015;10:S169-S170.
    • (2015) J Thorac Oncol , vol.10 , pp. S169-S170
    • Van Schil, P.1
  • 136
    • 84969798508 scopus 로고    scopus 로고
    • Primary study endpoint analysis for NRG Oncology/RTOG 0813 trial of stereotactic body radiation therapy (SBRT) for centrally located non-small cell lung cancer (NSCLC)
    • Bezjak A, Paulus R, Gaspar LE, et al. Primary study endpoint analysis for NRG Oncology/RTOG 0813 trial of stereotactic body radiation therapy (SBRT) for centrally located non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys. 2016;94:5-6.
    • (2016) Int J Radiat Oncol Biol Phys , vol.94 , pp. 5-6
    • Bezjak, A.1    Paulus, R.2    Gaspar, L.E.3
  • 137
    • 85027426469 scopus 로고    scopus 로고
    • Prospective phase 2 clinical trial of radiation dose-escalated stereotactic body radiation therapy (SBRT) for centrally located lung cancer: An institutional trial
    • Bradley JD, Gao F, Parikh PJ, et al. Prospective phase 2 clinical trial of radiation dose-escalated stereotactic body radiation therapy (SBRT) for centrally located lung cancer: an institutional trial. Int J Radiat Oncol Biol Phys. 2015;93:S101.
    • (2015) Int J Radiat Oncol Biol Phys , vol.93 , pp. S101
    • Bradley, J.D.1    Gao, F.2    Parikh, P.J.3
  • 138
    • 84875937242 scopus 로고    scopus 로고
    • Genotyping and genomic profiling of non-small-cell lung cancer: Implications for current and future therapies
    • Li T, Kung HJ, Mack PC, et al. Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies. J Clin Oncol. 2013;31:1039-1049.
    • (2013) J Clin Oncol , vol.31 , pp. 1039-1049
    • Li, T.1    Kung, H.J.2    Mack, P.C.3
  • 139
    • 84868309107 scopus 로고    scopus 로고
    • The transcriptional landscape and mutational profile of lung adenocarcinoma
    • Seo JS, Ju YS, Lee WC, et al. The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res. 2012;22:2109-2119.
    • (2012) Genome Res , vol.22 , pp. 2109-2119
    • Seo, J.S.1    Ju, Y.S.2    Lee, W.C.3
  • 140
    • 57149089886 scopus 로고    scopus 로고
    • EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: A historical comparison of patients treated before and after gefitinib approval in Japan
    • Takano T, Fukui T, Ohe Y, et al. EGFR mutations predict survival benefit from gefitinib in patients with advanced lung adenocarcinoma: a historical comparison of patients treated before and after gefitinib approval in Japan. J Clin Oncol. 2008;26:5589-5595.
    • (2008) J Clin Oncol , vol.26 , pp. 5589-5595
    • Takano, T.1    Fukui, T.2    Ohe, Y.3
  • 141
    • 80053386829 scopus 로고    scopus 로고
    • Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
    • Shaw AT, Yeap BY, Solomon BJ, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12: 1004-1012.
    • (2011) Lancet Oncol , vol.12 , pp. 1004-1012
    • Shaw, A.T.1    Yeap, B.Y.2    Solomon, B.J.3
  • 142
    • 84954394140 scopus 로고    scopus 로고
    • AZD9291 in pre-treated T790M positive advanced NSCLC: AURA2 phase II study
    • Mitsudomi T, Tsai C-M, Shepherd F, et al. AZD9291 in pre-treated T790M positive advanced NSCLC: AURA2 phase II study. J Thorac Oncol. 2015;10:S320.
    • (2015) J Thorac Oncol , vol.10 , pp. S320
    • Mitsudomi, T.1    Tsai, C.-M.2    Shepherd, F.3
  • 143
    • 85011846247 scopus 로고    scopus 로고
    • AZD9291 in pre-treated T790M positive advanced NSCLC: AURA study phase II extension cohort
    • Yang JC-H, Ahn M-J, Ramalingam SS, et al. AZD9291 in pre-treated T790M positive advanced NSCLC: AURA study phase II extension cohort. J Thorac Oncol. 2015;10:S319.
    • (2015) J Thorac Oncol , vol.10 , pp. S319
    • Jc-H, Y.1    Ahn, M.-J.2    Ramalingam, S.S.3
  • 144
    • 84969833645 scopus 로고    scopus 로고
    • A phase II trial of erlotinib (E) and bev-acizumab (B) in patients with advanced non-small-cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations with and without T790M mutation. The Spanish Lung Cancer Group (SLCG) and the European Thoracic Oncology Platform (ETOP) BELIEF trial
    • Stahel RA. A phase II trial of erlotinib (E) and bev-acizumab (B) in patients with advanced non-small-cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) mutations with and without T790M mutation. The Spanish Lung Cancer Group (SLCG) and the European Thoracic Oncology Platform (ETOP) BELIEF trial. Eur J Cancer. 2015;51:S711.
    • (2015) Eur J Cancer , vol.51 , pp. S711
    • Stahel, R.A.1
  • 145
    • 84942159469 scopus 로고    scopus 로고
    • Efficacy of rociletinib (CO-1686) in plasma-genotyped T790M-positive non-small cell lung cancer (NSCLC) patients (pts) [abstract]
    • Sequist LV, Goldman JW, Wakelee HA, et al. Efficacy of rociletinib (CO-1686) in plasma-genotyped T790M-positive non-small cell lung cancer (NSCLC) patients (pts) [abstract]. J Clin Oncol. 2015;33(suppl):8001.
    • (2015) J Clin Oncol , vol.33 , pp. 8001
    • Sequist, L.V.1    Goldman, J.W.2    Wakelee, H.A.3
  • 146
    • 84969834915 scopus 로고    scopus 로고
    • Comprehensive genomic profiling identifies a subset of crizotinib responsive ALK-rearranged NSCLC not detected by FISH
    • in press
    • Ali S, Hensing T, Schrock A, et al. Comprehensive genomic profiling identifies a subset of crizotinib responsive ALK-rearranged NSCLC not detected by FISH. Oncologist, in press.
    • Oncologist
    • Ali, S.1    Hensing, T.2    Schrock, A.3
  • 147
    • 84942521554 scopus 로고    scopus 로고
    • Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarci-nomas otherwise negative for such alterations by other genomic testing approaches
    • Drilon A, Wang L, Arcila ME, et al. Broad, hybrid capture-based next-generation sequencing identifies actionable genomic alterations in lung adenocarci-nomas otherwise negative for such alterations by other genomic testing approaches. Clin Cancer Res. 2015;21:3631-3639.
    • (2015) Clin Cancer Res , vol.21 , pp. 3631-3639
    • Drilon, A.1    Wang, L.2    Arcila, M.E.3
  • 148
    • 84931067455 scopus 로고    scopus 로고
    • Novel ALK fusion partners in lung cancer
    • Iyevleva AG, Raskin GA, Tiurin VI, et al. Novel ALK fusion partners in lung cancer. Cancer Lett. 2015;362:116-121.
    • (2015) Cancer Lett , vol.362 , pp. 116-121
    • Iyevleva, A.G.1    Raskin, G.A.2    Tiurin, V.I.3
  • 149
    • 84938270856 scopus 로고    scopus 로고
    • BIRC6-ALK, a novel fusion gene in ALK break-apart FISH-negative lung adenocar-cinoma, responds to crizotinib
    • Shan L, Jiang P, Xu F, et al. BIRC6-ALK, a novel fusion gene in ALK break-apart FISH-negative lung adenocar-cinoma, responds to crizotinib. J Thorac Oncol. 2015;10:e37-e39.
    • (2015) J Thorac Oncol , vol.10 , pp. e37-e39
    • Shan, L.1    Jiang, P.2    Xu, F.3
  • 150
    • 84941013285 scopus 로고    scopus 로고
    • RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer
    • Hrustanovic G, Olivas V, Pazarentzos E, et al. RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer. Nat Med. 2015;21: 1038-1047.
    • (2015) Nat Med , vol.21 , pp. 1038-1047
    • Hrustanovic, G.1    Olivas, V.2    Pazarentzos, E.3
  • 151
    • 84919443958 scopus 로고    scopus 로고
    • Patient-derived models of acquired resistance can identify effective drug combinations for cancer
    • Crystal AS, Shaw AT, Sequist LV, et al. Patient-derived models of acquired resistance can identify effective drug combinations for cancer. Science. 2014;346: 1480-1486.
    • (2014) Science , vol.346 , pp. 1480-1486
    • Crystal, A.S.1    Shaw, A.T.2    Sequist, L.V.3
  • 152
    • 84969768091 scopus 로고    scopus 로고
    • June 12, 2015 Accessed January 22, 2016
    • US Food and Drug Administration. Ventana ALK (D5F3) CDx assay. June 12, 2015. http://www.fda.gov/medical devices/productsandmedicalprocedures/deviceapprovalsand clearances/recently-approveddevices/ucm454476.htm. Accessed January 22, 2016.
    • Ventana ALK (D5F3) CDx Assay
  • 153
    • 84929508050 scopus 로고    scopus 로고
    • Clinical experience with crizotinib in patients with advanced ALK-rearranged non-small-cell lung cancer and brain me-tastases
    • Costa DB, Shaw AT, Ou SH, et al. Clinical experience with crizotinib in patients with advanced ALK-rearranged non-small-cell lung cancer and brain me-tastases. J Clin Oncol. 2015;33:1881-1888.
    • (2015) J Clin Oncol , vol.33 , pp. 1881-1888
    • Costa, D.B.1    Shaw, A.T.2    Ou, S.H.3
  • 154
    • 84922281943 scopus 로고    scopus 로고
    • Alectinib salvages CNS relapses in ALK-positive lung cancer patients previously treated with crizotinib and ceritinib
    • Gainor JF, Sherman CA, Willoughby K, et al. Alectinib salvages CNS relapses in ALK-positive lung cancer patients previously treated with crizotinib and ceritinib. J Thorac Oncol. 2015;10:232-236.
    • (2015) J Thorac Oncol , vol.10 , pp. 232-236
    • Gainor, J.F.1    Sherman, C.A.2    Willoughby, K.3
  • 155
    • 84922741549 scopus 로고    scopus 로고
    • Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis
    • Ou SH, Sommers KR, Azada MC, et al. Alectinib induces a durable (>15 months) complete response in an ALK-positive non-small cell lung cancer patient who progressed on crizotinib with diffuse leptomeningeal carcinomatosis. Oncologist. 2015;20:224-226.
    • (2015) Oncologist , vol.20 , pp. 224-226
    • Ou, S.H.1    Sommers, K.R.2    Azada, M.C.3
  • 156
    • 84964343904 scopus 로고    scopus 로고
    • Alectinib in crizotinib-refractory ALK-rearranged non-small-cell lung cancer: A phase II global study
    • Ou SI, Ahn JS, De Petris L, et al. Alectinib in crizotinib-refractory ALK-rearranged non-small-cell lung cancer: a phase II global study. J Clin Oncol. 2016;34:661-668.
    • (2016) J Clin Oncol , vol.34 , pp. 661-668
    • Ou, S.I.1    Ahn, J.S.2    De Petris, L.3
  • 157
    • 84959324643 scopus 로고    scopus 로고
    • Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: A single-group, multicentre, phase 2 trial
    • Shaw AT, Gandhi L, Gadgeel S, et al. Alectinib in ALK-positive, crizotinib-resistant, non-small-cell lung cancer: a single-group, multicentre, phase 2 trial. Lancet Oncol. 2016;17:234-242.
    • (2016) Lancet Oncol , vol.17 , pp. 234-242
    • Shaw, A.T.1    Gandhi, L.2    Gadgeel, S.3
  • 158
    • 84955293624 scopus 로고    scopus 로고
    • Clinical impact of sequential treatment with ALK-TKIs in patients with advanced ALK-positive non-small cell lung cancer: Results of a multicenter analysis
    • Chiari R, Metro G, Iacono D, et al. Clinical impact of sequential treatment with ALK-TKIs in patients with advanced ALK-positive non-small cell lung cancer: Results of a multicenter analysis. Lung Cancer. 2015;90: 255-260.
    • (2015) Lung Cancer , vol.90 , pp. 255-260
    • Chiari, R.1    Metro, G.2    Iacono, D.3
  • 159
    • 84938266539 scopus 로고    scopus 로고
    • Progression-free and overall survival in ALK-positive NSCLC patients treated with sequential crizotinib and ceritinib
    • Gainor JF, Tan DS, De Pas T, et al. Progression-free and overall survival in ALK-positive NSCLC patients treated with sequential crizotinib and ceritinib. Clin Cancer Res. 2015;21:2745-2752.
    • (2015) Clin Cancer Res , vol.21 , pp. 2745-2752
    • Gainor, J.F.1    Tan, D.S.2    De Pas, T.3
  • 160
    • 84951827380 scopus 로고    scopus 로고
    • Clinical activity and safety of PF-06463922 from a dose escalation study in patients with advanced ALK+ or ROS1+ NSCLC [abstract]
    • Shaw AT, Bauer TM, Felip E, et al. Clinical activity and safety of PF-06463922 from a dose escalation study in patients with advanced ALK+ or ROS1+ NSCLC [abstract]. J Clin Oncol. 2015;33(suppl):8018.
    • (2015) J Clin Oncol , vol.33 , pp. 8018
    • Shaw, A.T.1    Bauer, T.M.2    Felip, E.3
  • 161
    • 84937521317 scopus 로고    scopus 로고
    • PF-06463922, an ALK/ROS1 inhibitor, overcomes resistance to first and second generation alk inhibitors in preclinical models
    • Zou HY, Friboulet L, Kodack DP, et al. PF-06463922, an ALK/ROS1 inhibitor, overcomes resistance to first and second generation alk inhibitors in preclinical models. Cancer Cell. 2015;28:70-81.
    • (2015) Cancer Cell , vol.28 , pp. 70-81
    • Zou, H.Y.1    Friboulet, L.2    Kodack, D.P.3
  • 162
    • 84925307919 scopus 로고    scopus 로고
    • PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations
    • Zou HY, Li Q, Engstrom LD, et al. PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations. Proc Natl Acad Sci USA. 2015;112:3493-3498.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 3493-3498
    • Zou, H.Y.1    Li, Q.2    Engstrom, L.D.3
  • 163
    • 84926421697 scopus 로고    scopus 로고
    • I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib
    • Ou SH, Greenbowe J, Khan ZU, et al. I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib. Lung Cancer. 2015;88:231-234.
    • (2015) Lung Cancer , vol.88 , pp. 231-234
    • Ou, S.H.1    Greenbowe, J.2    Khan, Z.U.3
  • 164
    • 84955184379 scopus 로고    scopus 로고
    • ALK F1174V mutation confers sensitivity while ALK I1171 mutation confers resistance to alectinib. The importance of serial biopsy post progression
    • Ou SH, Milliken JC, Azada MC, et al. ALK F1174V mutation confers sensitivity while ALK I1171 mutation confers resistance to alectinib. The importance of serial biopsy post progression. Lung Cancer. 2016;91:70-72.
    • (2016) Lung Cancer , vol.91 , pp. 70-72
    • Ou, S.H.1    Milliken, J.C.2    Azada, M.C.3
  • 165
    • 84969884306 scopus 로고    scopus 로고
    • A novel acquired ALK F1245C mutation confers resistance to crizotinib in ALK-positive NSCLC but is sensitive to ceritinib
    • Kodityal S, Elvin JA, Squillace R, et al. A novel acquired ALK F1245C mutation confers resistance to crizotinib in ALK-positive NSCLC but is sensitive to ceritinib. Lung Cancer. 2016;92:19-21.
    • (2016) Lung Cancer , vol.92 , pp. 19-21
    • Kodityal, S.1    Elvin, J.A.2    Squillace, R.3
  • 166
    • 84930609398 scopus 로고    scopus 로고
    • Identification of a novel ALK G1123S mutation in a patient with ALK-rearranged non-small-cell lung cancer exhibiting resistance to ceritinib
    • Toyokawa G, Inamasu E, Shimamatsu S, et al. Identification of a novel ALK G1123S mutation in a patient with ALK-rearranged non-small-cell lung cancer exhibiting resistance to ceritinib. J Thorac Oncol. 2015;10: e55-e57.
    • (2015) J Thorac Oncol , vol.10 , pp. e55-e57
    • Toyokawa, G.1    Inamasu, E.2    Shimamatsu, S.3
  • 167
    • 84954050562 scopus 로고    scopus 로고
    • Resensitization to crizotinib by the lorlatinib ALK resistance mutation L1198F
    • Shaw AT, Friboulet L, Leshchiner I, et al. Resensitization to crizotinib by the lorlatinib ALK resistance mutation L1198F. N Engl J Med. 2016;374:54-61.
    • (2016) N Engl J Med , vol.374 , pp. 54-61
    • Shaw, A.T.1    Friboulet, L.2    Leshchiner, I.3
  • 168
    • 84929501704 scopus 로고    scopus 로고
    • Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocar-cinoma by comprehensive genomic profiling
    • Ou SH, Chalmers ZR, Azada MC, et al. Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocar-cinoma by comprehensive genomic profiling. Lung Cancer. 2015;88:352-354.
    • (2015) Lung Cancer , vol.88 , pp. 352-354
    • Ou, S.H.1    Chalmers, Z.R.2    Azada, M.C.3
  • 169
    • 84911372597 scopus 로고    scopus 로고
    • Crizotinib in ROS1-rearranged non-small-cell lung cancer
    • Shaw AT, Ou SH, Bang YJ, et al. Crizotinib in ROS1-rearranged non-small-cell lung cancer. N Engl J Med. 2014;371:1963-1971.
    • (2014) N Engl J Med , vol.371 , pp. 1963-1971
    • Shaw, A.T.1    Ou, S.H.2    Bang, Y.J.3
  • 170
    • 84925582188 scopus 로고    scopus 로고
    • Anchored multiplex PCR for targeted next-generation sequencing
    • Zheng Z, Liebers M, Zhelyazkova B, et al. Anchored multiplex PCR for targeted next-generation sequencing. Nat Med. 2014;20:1479-1484.
    • (2014) Nat Med , vol.20 , pp. 1479-1484
    • Zheng, Z.1    Liebers, M.2    Zhelyazkova, B.3
  • 171
    • 84953888757 scopus 로고    scopus 로고
    • Clinicopathologic characteristics of patients with ROS1 fusion gene in non-small cell lung cancer: A meta-analysis
    • Zhu Q, Zhan P, Zhang X, et al. Clinicopathologic characteristics of patients with ROS1 fusion gene in non-small cell lung cancer: a meta-analysis. Transl Lung Cancer Res. 2015;4:300-309.
    • (2015) Transl Lung Cancer Res , vol.4 , pp. 300-309
    • Zhu, Q.1    Zhan, P.2    Zhang, X.3
  • 172
    • 84969881701 scopus 로고    scopus 로고
    • Pfizer announces U.S. FDA acceptance and priority review of supplemental new drug application for Xalkori (crizo-tinib) for the treatment of patients with ROS1-positive metastatic non-small cell lung cancer [press release]. New York, NY: Pfizer; December 8, 2015 Accessed January 22, 2015
    • Pfizer announces U.S. FDA acceptance and priority review of supplemental new drug application for Xalkori (crizo-tinib) for the treatment of patients with ROS1-positive metastatic non-small cell lung cancer [press release]. New York, NY: Pfizer; December 8, 2015. http://press.pfizer.com/press-release/pfizer-announces-us-fda-acceptance-and-priority-review-supplemental-new-drug-applicati. Accessed January 22, 2015.
  • 173
    • 84927139647 scopus 로고    scopus 로고
    • Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: Results from the EUROS1 cohort
    • Mazieres J, Zalcman G, Crino L, et al. Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort. J Clin Oncol. 2015;33:992-999.
    • (2015) J Clin Oncol , vol.33 , pp. 992-999
    • Mazieres, J.1    Zalcman, G.2    Crino, L.3
  • 175
    • 84879088863 scopus 로고    scopus 로고
    • Acquired resistance to crizotinib from a mutation in CD74-ROS1
    • Awad MM, Katayama R, McTigue M, et al. Acquired resistance to crizotinib from a mutation in CD74-ROS1. N Engl J Med. 2013;368:2395-2401.
    • (2013) N Engl J Med , vol.368 , pp. 2395-2401
    • Awad, M.M.1    Katayama, R.2    McTigue, M.3
  • 176
    • 84930968377 scopus 로고    scopus 로고
    • Molecular changes associated with acquired resistance to crizotinib in ros1-rearranged non-small cell lung cancer
    • Song A, Kim TM, Kim DW, et al. Molecular changes associated with acquired resistance to crizotinib in ros1-rearranged non-small cell lung cancer. Clin Cancer Res. 2015;21:2379-2387.
    • (2015) Clin Cancer Res , vol.21 , pp. 2379-2387
    • Song, A.1    Kim, T.M.2    Kim, D.W.3
  • 177
    • 84969257134 scopus 로고    scopus 로고
    • A novel crizotinib-resistant solvent-front mutation responsive to cabo-zantinib therapy in a patient with ROS1-rearranged lung cancer [e-pub ahead of print]
    • accessed March 11, 2016
    • Drilon A, Somwar R, Wagner JP, et al. A novel crizotinib-resistant solvent-front mutation responsive to cabo-zantinib therapy in a patient with ROS1-rearranged lung cancer [e-pub ahead of print]. Clin Cancer Res. http://dx.doi.org/10.1158/1078-0432.CCR-15-2013, accessed March 11, 2016.
    • Clin Cancer Res
    • Drilon, A.1    Somwar, R.2    Wagner, J.P.3
  • 178
    • 84991491028 scopus 로고    scopus 로고
    • Afatinib (A) vs gefitinib (G) as first-line treatment for patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring activating EGFR mutations: Results of the global, randomized, open-label, phase IIb trial LUX-Lung 7 (LL7)
    • Park K, Tan E-H, Zhang L, et al. Afatinib (A) vs gefitinib (G) as first-line treatment for patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring activating EGFR mutations: results of the global, randomized, open-label, phase IIb trial LUX-Lung 7 (LL7). Ann Oncol. 2015;26:ix161-ix162.
    • (2015) Ann Oncol , vol.26 , pp. ix161-ix162
    • Park, K.1    Tan, E.-H.2    Zhang, L.3
  • 179
    • 84877100240 scopus 로고    scopus 로고
    • Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers
    • Yu HA, Arcila ME, Rekhtman N, et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers. Clin Cancer Res. 2013;19:2240-2247.
    • (2013) Clin Cancer Res , vol.19 , pp. 2240-2247
    • Yu, H.A.1    Arcila, M.E.2    Rekhtman, N.3
  • 181
    • 84937518476 scopus 로고    scopus 로고
    • Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): An open-label, randomised, controlled phase 3 trial
    • Thatcher N, Hirsch FR, Luft AV, et al. Necitumumab plus gemcitabine and cisplatin versus gemcitabine and cisplatin alone as first-line therapy in patients with stage IV squamous non-small-cell lung cancer (SQUIRE): an open-label, randomised, controlled phase 3 trial. Lancet Oncol. 2015;16:763-774.
    • (2015) Lancet Oncol , vol.16 , pp. 763-774
    • Thatcher, N.1    Hirsch, F.R.2    Luft, A.V.3
  • 182
    • 84938210278 scopus 로고    scopus 로고
    • Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): An open-label randomised controlled phase 3 trial
    • Soria JC, Felip E, Cobo M, et al. Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial. Lancet Oncol. 2015;16:897-907.
    • (2015) Lancet Oncol , vol.16 , pp. 897-907
    • Soria, J.C.1    Felip, E.2    Cobo, M.3
  • 184
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature. 2002;417:949-954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1    Bignell, G.R.2    Cox, C.3
  • 185
    • 84901826745 scopus 로고    scopus 로고
    • Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations
    • Kinno T, Tsuta K, Shiraishi K, et al. Clinicopathological features of nonsmall cell lung carcinomas with BRAF mutations. Ann Oncol. 2014;25:138-142.
    • (2014) Ann Oncol , vol.25 , pp. 138-142
    • Kinno, T.1    Tsuta, K.2    Shiraishi, K.3
  • 186
    • 84922228061 scopus 로고    scopus 로고
    • Clinical characteristics and course of 63 patients with BRAF mutant lung cancers
    • Litvak AM, Paik PK, Woo KM, et al. Clinical characteristics and course of 63 patients with BRAF mutant lung cancers. J Thorac Oncol. 2014;9:1669-1674.
    • (2014) J Thorac Oncol , vol.9 , pp. 1669-1674
    • Litvak, A.M.1    Paik, P.K.2    Woo, K.M.3
  • 187
    • 80053014471 scopus 로고    scopus 로고
    • Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations
    • Marchetti A, Felicioni L, Malatesta S, et al. Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. J Clin Oncol. 2011;29:3574-3579.
    • (2011) J Clin Oncol , vol.29 , pp. 3574-3579
    • Marchetti, A.1    Felicioni, L.2    Malatesta, S.3
  • 188
    • 79956316170 scopus 로고    scopus 로고
    • Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations
    • Paik PK, Arcila ME, Fara M, et al. Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations. J Clin Oncol. 2011;29:2046-2051.
    • (2011) J Clin Oncol , vol.29 , pp. 2046-2051
    • Paik, P.K.1    Arcila, M.E.2    Fara, M.3
  • 189
    • 84884999688 scopus 로고    scopus 로고
    • Interim results of phase II study BRF113928 of dabrafenib in BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) patients [abstract]
    • Planchard D, Mazieres J, Riely GJ, et al. Interim results of phase II study BRF113928 of dabrafenib in BRAF V600E mutation-positive non-small cell lung cancer (NSCLC) patients [abstract]. J Clin Oncol. 2013;31(suppl):8009.
    • (2013) J Clin Oncol , vol.31 , pp. 8009
    • Planchard, D.1    Mazieres, J.2    Riely, G.J.3
  • 190
    • 84942524970 scopus 로고    scopus 로고
    • Interim results of a phase II study of the BRAF inhibitor (BRAFi) dab-rafenib (D) in combination with the MEK inhibitor tra-metinib (T) in patients (pts) with BRAF V600E mutated (mut) metastatic non-small cell lung cancer (NSCLC) [abstract]
    • Planchard D, Groen HJM, Kim TM, et al. Interim results of a phase II study of the BRAF inhibitor (BRAFi) dab-rafenib (D) in combination with the MEK inhibitor tra-metinib (T) in patients (pts) with BRAF V600E mutated (mut) metastatic non-small cell lung cancer (NSCLC) [abstract]. J Clin Oncol. 2015;33(suppl):8006.
    • (2015) J Clin Oncol , vol.33 , pp. 8006
    • Planchard, D.1    Hjm, G.2    Kim, T.M.3
  • 191
    • 84866595717 scopus 로고    scopus 로고
    • A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib
    • Gautschi O, Pauli C, Strobel K, et al. A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib. J Thorac Oncol. 2012;7:e23-e24.
    • (2012) J Thorac Oncol , vol.7 , pp. e23-e24
    • Gautschi, O.1    Pauli, C.2    Strobel, K.3
  • 192
    • 84887014975 scopus 로고    scopus 로고
    • Lung adenocarci-noma with BRAF G469L mutation refractory to vemur-afenib
    • Gautschi O, Peters S, Zoete V, et al. Lung adenocarci-noma with BRAF G469L mutation refractory to vemur-afenib. Lung Cancer. 2013;82:365-367.
    • (2013) Lung Cancer , vol.82 , pp. 365-367
    • Gautschi, O.1    Peters, S.2    Zoete, V.3
  • 193
    • 84883879311 scopus 로고    scopus 로고
    • Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma
    • Peters S, Michielin O, Zimmermann S. Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma. J Clin Oncol. 2013;31:e341-e344.
    • (2013) J Clin Oncol , vol.31 , pp. e341-e344
    • Peters, S.1    Michielin, O.2    Zimmermann, S.3
  • 194
    • 84904098850 scopus 로고    scopus 로고
    • BRAF V600E-mutated lung adenocarcinoma with metastases to the brain responding to treatment with vemurafenib
    • Robinson SD, O'Shaughnessy JA, Cowey CL, et al. BRAF V600E-mutated lung adenocarcinoma with metastases to the brain responding to treatment with vemurafenib. Lung Cancer. 2014;85:326-330.
    • (2014) Lung Cancer , vol.85 , pp. 326-330
    • Robinson, S.D.1    O'Shaughnessy, J.A.2    Cowey, C.L.3
  • 195
    • 0035883542 scopus 로고    scopus 로고
    • Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung
    • Ahrendt SA, Decker PA, Alawi EA, et al. Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung. Cancer. 2001;92:1525-1530.
    • (2001) Cancer , vol.92 , pp. 1525-1530
    • Ahrendt, S.A.1    Decker, P.A.2    Alawi, E.A.3
  • 196
    • 53249145767 scopus 로고    scopus 로고
    • Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma
    • Riely GJ, Kris MG, Rosenbaum D, et al. Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. Clin Cancer Res. 2008;14:5731-5734.
    • (2008) Clin Cancer Res , vol.14 , pp. 5731-5734
    • Riely, G.J.1    Kris, M.G.2    Rosenbaum, D.3
  • 197
    • 82355191818 scopus 로고    scopus 로고
    • Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
    • Sequist LV, Heist RS, Shaw AT, et al. Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol. 2011;22: 2616-2624.
    • (2011) Ann Oncol , vol.22 , pp. 2616-2624
    • Sequist, L.V.1    Heist, R.S.2    Shaw, A.T.3
  • 198
    • 78049515002 scopus 로고    scopus 로고
    • Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases
    • Sun Y, Ren Y, Fang Z, et al. Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases. J Clin Oncol. 2010;28:4616-4620.
    • (2010) J Clin Oncol , vol.28 , pp. 4616-4620
    • Sun, Y.1    Ren, Y.2    Fang, Z.3
  • 199
    • 84871720411 scopus 로고    scopus 로고
    • Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study
    • Janne PA, Shaw AT, Pereira JR, et al. Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study. Lancet Oncol. 2013;14:38-47.
    • (2013) Lancet Oncol , vol.14 , pp. 38-47
    • Janne, P.A.1    Shaw, A.T.2    Pereira, J.R.3
  • 200
    • 84896711084 scopus 로고    scopus 로고
    • Two parallel randomized phase II studies of selumetinib (S) and erlotinib (E) in advanced non-small cell lung cancer selected by KRAS mutations [abstract]
    • Carter CA, Rajan A, Szabo E, et al. Two parallel randomized phase II studies of selumetinib (S) and erlotinib (E) in advanced non-small cell lung cancer selected by KRAS mutations [abstract]. J Clin Oncol. 2013;31(suppl):8026.
    • (2013) J Clin Oncol , vol.31 , pp. 8026
    • Carter, C.A.1    Rajan, A.2    Szabo, E.3
  • 201
    • 84894491192 scopus 로고    scopus 로고
    • MEK114653: A randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS-mutant advanced non-small cell lung cancer (NSCLC) [abstract]
    • Blumenschein GR, Smit EF, Planchard D, et al. MEK114653: A randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS-mutant advanced non-small cell lung cancer (NSCLC) [abstract]. J Clin Oncol. 2013;31(suppl):8029.
    • (2013) J Clin Oncol , vol.31 , pp. 8029
    • Blumenschein, G.R.1    Smit, E.F.2    Planchard, D.3
  • 202
    • 84894467946 scopus 로고    scopus 로고
    • Oral MEK1/MEK2 inhibitor trametinib (GSK1120212) in combination with docetaxel in KRAS-mutant and wild-type (WT) advanced non-small cell lung cancer (NSCLC): A phase I/Ib trial [abstract]
    • Gandara DR, Hiret S, Blumenschein GR, et al. Oral MEK1/MEK2 inhibitor trametinib (GSK1120212) in combination with docetaxel in KRAS-mutant and wild-type (WT) advanced non-small cell lung cancer (NSCLC): A phase I/Ib trial [abstract]. J Clin Oncol. 2013;31(suppl): 8028.
    • (2013) J Clin Oncol , vol.31 , pp. 8028
    • Gandara, D.R.1    Hiret, S.2    Blumenschein, G.R.3
  • 203
    • 84895918947 scopus 로고    scopus 로고
    • Oral MEK1/MEK2 inhibitor trametinib (GSK1120212) in combination with pemetrexed for KRAS-mutant and wild-type (WT) advanced non-small cell lung cancer (NSCLC): A phase I/Ib trial [abstract]
    • Kelly K, Mazieres J, Leighl NB, et al. Oral MEK1/MEK2 inhibitor trametinib (GSK1120212) in combination with pemetrexed for KRAS-mutant and wild-type (WT) advanced non-small cell lung cancer (NSCLC): A phase I/Ib trial [abstract]. J Clin Oncol. 2013;31(suppl):8027.
    • (2013) J Clin Oncol , vol.31 , pp. 8027
    • Kelly, K.1    Mazieres, J.2    Leighl, N.B.3
  • 204
    • 84940394869 scopus 로고    scopus 로고
    • Phase III multinational, randomized, double-blind, placebo-controlled study of tivantinib (ARQ 197) plus erlotinib versus erlotinib alone in previously treated patients with locally advanced or metastatic nonsquamous non-small-cell lung cancer
    • Scagliotti G, von Pawel J, Novello S, et al. Phase III multinational, randomized, double-blind, placebo-controlled study of tivantinib (ARQ 197) plus erlotinib versus erlotinib alone in previously treated patients with locally advanced or metastatic nonsquamous non-small-cell lung cancer. J Clin Oncol. 2015;33:2667-2674.
    • (2015) J Clin Oncol , vol.33 , pp. 2667-2674
    • Scagliotti, G.1    Von Pawel, J.2    Novello, S.3
  • 205
    • 80051974548 scopus 로고    scopus 로고
    • Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
    • Sequist LV, von Pawel J, Garmey EG, et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol. 2011;29:3307-3315.
    • (2011) J Clin Oncol , vol.29 , pp. 3307-3315
    • Sequist, L.V.1    Von Pawel, J.2    Garmey, E.G.3
  • 206
    • 85027426476 scopus 로고    scopus 로고
    • Phase II study of defactinib, VS-6063, a focal adhesion kinase (FAK) inhibitor, in patients with KRAS mutant non-small cell lung cancer (NSCLC)
    • Gerber DE, Camidge DR, Morgensztern D, et al. Phase II study of defactinib, VS-6063, a focal adhesion kinase (FAK) inhibitor, in patients with KRAS mutant non-small cell lung cancer (NSCLC). J Thorac Oncol. 2015;10:S372.
    • (2015) J Thorac Oncol , vol.10 , pp. S372
    • De, G.1    Camidge, D.R.2    Morgensztern, D.3
  • 207
    • 84938794719 scopus 로고    scopus 로고
    • Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities
    • Skoulidis F, Byers LA, Diao L, et al. Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov. 2015;5:860-877.
    • (2015) Cancer Discov , vol.5 , pp. 860-877
    • Skoulidis, F.1    Byers, L.A.2    Diao, L.3
  • 208
    • 84857929267 scopus 로고    scopus 로고
    • KIF5B-RET fusions in lung adenocarcinoma
    • Kohno T, Ichikawa H, Totoki Y, et al. KIF5B-RET fusions in lung adenocarcinoma. Nat Med. 2012;18:375-377.
    • (2012) Nat Med , vol.18 , pp. 375-377
    • Kohno, T.1    Ichikawa, H.2    Totoki, Y.3
  • 209
    • 84857985225 scopus 로고    scopus 로고
    • RET ROS1 and ALK fusions in lung cancer
    • Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med. 2012;18:378-381.
    • (2012) Nat Med , vol.18 , pp. 378-381
    • Takeuchi, K.1    Soda, M.2    Togashi, Y.3
  • 210
    • 84870748688 scopus 로고    scopus 로고
    • RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer
    • Wang R, Hu H, Pan Y, et al. RET fusions define a unique molecular and clinicopathologic subtype of non-small-cell lung cancer. J Clin Oncol. 2012;30:4352-4359.
    • (2012) J Clin Oncol , vol.30 , pp. 4352-4359
    • Wang, R.1    Hu, H.2    Pan, Y.3
  • 211
    • 84925825363 scopus 로고    scopus 로고
    • RET-rearranged lung adenocarcinomas with lymphangitic spread, psammoma bodies, and clinical responses to cabozantinib
    • Mukhopadhyay S, Pennell NA, Ali SM, et al. RET-rearranged lung adenocarcinomas with lymphangitic spread, psammoma bodies, and clinical responses to cabozantinib. J Thorac Oncol. 2014;9:1714-1719.
    • (2014) J Thorac Oncol , vol.9 , pp. 1714-1719
    • Mukhopadhyay, S.1    Pennell, N.A.2    Ali, S.M.3
  • 212
    • 84959320806 scopus 로고    scopus 로고
    • Clinicopatho-logical characteristics of RET rearranged lung cancer in European patients
    • Michels S, Scheel AH, Scheffler M, et al. Clinicopatho-logical characteristics of RET rearranged lung cancer in European patients. J Thorac Oncol. 2016;11:122-127.
    • (2016) J Thorac Oncol , vol.11 , pp. 122-127
    • Michels, S.1    Scheel, A.H.2    Scheffler, M.3
  • 213
    • 85027426319 scopus 로고    scopus 로고
    • Clinical outcomes with pemetrexed-based systemic therapy in RET-rearranged lung cancers
    • Drilon A, Bergagnin I, Delasos L, et al. Clinical outcomes with pemetrexed-based systemic therapy in RET-rearranged lung cancers. J Thorac Oncol. 2015;10:S178.
    • (2015) J Thorac Oncol , vol.10 , pp. S178
    • Drilon, A.1    Bergagnin, I.2    Delasos, L.3
  • 214
    • 84878858856 scopus 로고    scopus 로고
    • Response to cabozantinib in patients with RET fusion-positive lung adenocarcinomas
    • Drilon A, Wang L, Hasanovic A, et al. Response to cabozantinib in patients with RET fusion-positive lung adenocarcinomas. Cancer Discov. 2013;3:630-635.
    • (2013) Cancer Discov , vol.3 , pp. 630-635
    • Drilon, A.1    Wang, L.2    Hasanovic, A.3
  • 215
    • 84969533090 scopus 로고    scopus 로고
    • Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer [e-pub ahead of print]
    • accessed March 11, 2016
    • Falchook GS, Ordonez NG, Bastida CC, et al. Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer [e-pub ahead of print]. J Clin Oncol. http://dx.doi.org/10.1200/JCO.2013.50.5016, accessed March 11, 2016.
    • J Clin Oncol
    • Falchook, G.S.1    Ordonez, N.G.2    Bastida, C.C.3
  • 216
    • 84876383602 scopus 로고    scopus 로고
    • A patient with lung adenocarcinoma and RET fusion treated with van-detanib
    • Gautschi O, Zander T, Keller FA, et al. A patient with lung adenocarcinoma and RET fusion treated with van-detanib. J Thorac Oncol. 2013;8:e43-e44.
    • (2013) J Thorac Oncol , vol.8 , pp. e43-e44
    • Gautschi, O.1    Zander, T.2    Keller, F.A.3
  • 217
    • 84918504885 scopus 로고    scopus 로고
    • Alectinib shows potent antitumor activity against RET-rearranged non-small cell lung cancer
    • Kodama T, Tsukaguchi T, Satoh Y, et al. Alectinib shows potent antitumor activity against RET-rearranged non-small cell lung cancer. Mol Cancer Ther. 2014;13: 2910-2918.
    • (2014) Mol Cancer Ther , vol.13 , pp. 2910-2918
    • Kodama, T.1    Tsukaguchi, T.2    Satoh, Y.3
  • 218
    • 84862776857 scopus 로고    scopus 로고
    • Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
    • Lipson D, Capelletti M, Yelensky R, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med. 2012;18:382-384.
    • (2012) Nat Med , vol.18 , pp. 382-384
    • Lipson, D.1    Capelletti, M.2    Yelensky, R.3
  • 219
    • 41749097250 scopus 로고    scopus 로고
    • MET gene copy number in non-small cell lung cancer: Molecular analysis in a targeted tyrosine kinase inhibitor naive cohort
    • Beau-Faller M, Ruppert AM, Voegeli AC, et al. MET gene copy number in non-small cell lung cancer: molecular analysis in a targeted tyrosine kinase inhibitor naive cohort. J Thorac Oncol. 2008;3:331-339.
    • (2008) J Thorac Oncol , vol.3 , pp. 331-339
    • Beau-Faller, M.1    Ruppert, A.M.2    Voegeli, A.C.3
  • 220
    • 63849163410 scopus 로고    scopus 로고
    • Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
    • Cappuzzo F, Marchetti A, Skokan M, et al. Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. J Clin Oncol. 2009;27:1667-1674.
    • (2009) J Clin Oncol , vol.27 , pp. 1667-1674
    • Cappuzzo, F.1    Marchetti, A.2    Skokan, M.3
  • 221
    • 0029803612 scopus 로고    scopus 로고
    • Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance
    • Ichimura E, Maeshima A, Nakajima T, et al. Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance. Jpn J Cancer Res. 1996;87:1063-1069.
    • (1996) Jpn J Cancer Res , vol.87 , pp. 1063-1069
    • Ichimura, E.1    Maeshima, A.2    Nakajima, T.3
  • 222
    • 85027426509 scopus 로고    scopus 로고
    • Activity of crizotinib in METamplified NSCLC: Preliminary results of the AcSé trial
    • Moro-Sibilot D, Le Deley M-C, Zalcman G, et al. Activity of crizotinib in METamplified NSCLC: preliminary results of the AcSé trial. J Thorac Oncol. 2015;10:S178.
    • (2015) J Thorac Oncol , vol.10 , pp. S178
    • Moro-Sibilot, D.1    Le Deley, M.-C.2    Zalcman, G.3
  • 223
    • 61549138135 scopus 로고    scopus 로고
    • Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers
    • Onozato R, Kosaka T, Kuwano H, et al. Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers. J Thorac Oncol. 2009;4:5-11.
    • (2009) J Thorac Oncol , vol.4 , pp. 5-11
    • Onozato, R.1    Kosaka, T.2    Kuwano, H.3
  • 224
    • 84902811306 scopus 로고    scopus 로고
    • Efficacy and safety of crizotinib in patients with advanced c-MET-amplified non-small cell lung cancer (NSCLC)
    • Camidge D, Ou S, Shapiro G, et al. Efficacy and safety of crizotinib in patients with advanced c-MET-amplified non-small cell lung cancer (NSCLC). J Clin Oncol. 2014:32.
    • (2014) J Clin Oncol , vol.32
    • Camidge, D.1    Ou, S.2    Shapiro, G.3
  • 225
    • 79955458487 scopus 로고    scopus 로고
    • Activity of crizo-tinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification
    • Ou SH, Kwak EL, Siwak-Tapp C, et al. Activity of crizo-tinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol. 2011;6: 942-946.
    • (2011) J Thorac Oncol , vol.6 , pp. 942-946
    • Ou, S.H.1    Kwak, E.L.2    Siwak-Tapp, C.3
  • 226
    • 84969880498 scopus 로고    scopus 로고
    • MARQUEE: A randomized, double-blind, placebo-controlled, phase 3 trial of tivantinib (ARQ 197) plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, non-squamous, non-small-cell lung cancer (NSCLC)
    • Scagliotti G, Novello S, Ramlau R, et al. MARQUEE: A randomized, double-blind, placebo-controlled, phase 3 trial of tivantinib (ARQ 197) plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, non-squamous, non-small-cell lung cancer (NSCLC). Eur J Cancer. 2013;49:S798-S799.
    • (2013) Eur J Cancer , vol.49 , pp. S798-S799
    • Scagliotti, G.1    Novello, S.2    Ramlau, R.3
  • 227
    • 84865506979 scopus 로고    scopus 로고
    • Rationale and design of MARQUEE: A phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer
    • Scagliotti GV, Novello S, Schiller JH, et al. Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer. Clin Lung Cancer. 2012;13: 391-395.
    • (2012) Clin Lung Cancer , vol.13 , pp. 391-395
    • Scagliotti, G.V.1    Novello, S.2    Schiller, J.H.3
  • 228
    • 84938815085 scopus 로고    scopus 로고
    • Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping
    • Paik PK, Drilon A, Fan PD, et al. Response to MET inhibitors in patients with stage IV lung adenocarcinomas harboring MET mutations causing exon 14 skipping. Cancer Discov. 2015;5:842-849.
    • (2015) Cancer Discov , vol.5 , pp. 842-849
    • Paik, P.K.1    Drilon, A.2    Fan, P.D.3
  • 229
    • 84947874927 scopus 로고    scopus 로고
    • Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations
    • Liu X, Jia Y, Stoopler MB, et al. Next-generation sequencing of pulmonary sarcomatoid carcinoma reveals high frequency of actionable MET gene mutations. J Clin Oncol. 2015.
    • (2015) J Clin Oncol
    • Liu, X.1    Jia, Y.2    Stoopler, M.B.3
  • 230
    • 84948117368 scopus 로고    scopus 로고
    • Durable clinical response to entrectinib in NTRK1-rearranged non-small cell lung cancer
    • Farago AF, Le LP, Zheng Z, et al. Durable clinical response to entrectinib in NTRK1-rearranged non-small cell lung cancer. J Thorac Oncol. 2015;10:1670-1674.
    • (2015) J Thorac Oncol , vol.10 , pp. 1670-1674
    • Farago, A.F.1    Le, L.P.2    Zheng, Z.3
  • 231
    • 84887445619 scopus 로고    scopus 로고
    • Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
    • Vaishnavi A, Capelletti M, Le AT, et al. Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer. Nat Med. 2013;19:1469-1472.
    • (2013) Nat Med , vol.19 , pp. 1469-1472
    • Vaishnavi, A.1    Capelletti Le M, A.T.2
  • 232
    • 84880706152 scopus 로고    scopus 로고
    • Oncology meets immunology: The cancer-immunity cycle
    • Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013;39:1-10.
    • (2013) Immunity , vol.39 , pp. 1-10
    • Chen, D.S.1    Mellman, I.2
  • 233
    • 84880732199 scopus 로고    scopus 로고
    • Survival and long-term follow-up of safety and response in patients (pts) with advanced melanoma (MEL) in a phase 1 trial of nivolumab (anti-PD-1; BMS-936558; ONO-4538) [abstract]
    • Sznol M, Kluger HM, Hodi FS, et al. Survival and long-term follow-up of safety and response in patients (pts) with advanced melanoma (MEL) in a phase 1 trial of nivolumab (anti-PD-1; BMS-936558; ONO-4538) [abstract]. J Clin Oncol. 2013;31(suppl):CRA9006.
    • (2013) J Clin Oncol , vol.31 , pp. CRA9006
    • Sznol, M.1    Kluger, H.M.2    Hodi, F.S.3
  • 234
    • 84924901863 scopus 로고    scopus 로고
    • Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squa-mous non-small-cell lung cancer (CheckMate 063): A phase 2, single-arm trial
    • Rizvi NA, Mazieres J, Planchard D, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squa-mous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16: 257-265.
    • (2015) Lancet Oncol , vol.16 , pp. 257-265
    • Rizvi, N.A.1    Mazieres, J.2    Planchard, D.3
  • 235
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus Docetaxel in advanced squamous-cell non-small-cell lung cancer
    • Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus Docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373:123-135.
    • (2015) N Engl J Med , vol.373 , pp. 123-135
    • Brahmer, J.1    Reckamp, K.L.2    Baas, P.3
  • 236
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • Borghaei H, Paz-Ares L, Horn L, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med. 2015;373:1627-1639.
    • (2015) N Engl J Med , vol.373 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3
  • 237
    • 84929481480 scopus 로고    scopus 로고
    • Pembrolizumab for the treatment of non-small-cell lung cancer
    • Garon EB, Rizvi NA, Hui R, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015;372:2018-2028.
    • (2015) N Engl J Med , vol.372 , pp. 2018-2028
    • Garon, E.B.1    Rizvi, N.A.2    Hui, R.3
  • 238
    • 84950117835 scopus 로고    scopus 로고
    • Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEY-NOTE-010): A randomised controlled trial [e-pub ahead of print]
    • accessed March 11, 2016
    • Herbst RS, Baas P, Kim DW, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEY-NOTE-010): a randomised controlled trial [e-pub ahead of print]. Lancet. http://dx.doi.org/10.1016/S0140-6736(15)01281-7, accessed March 11, 2016.
    • Lancet
    • Herbst, R.S.1    Baas, P.2    Kim, D.W.3
  • 239
    • 84962038946 scopus 로고    scopus 로고
    • Atezolizu-mab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): A multi-centre, open-label, phase 2 randomised controlled trial [e-pub ahead of print]
    • accessed March 29, 2016
    • Fehrenbacher L, Spira A, Ballinger M, et al. Atezolizu-mab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multi-centre, open-label, phase 2 randomised controlled trial [e-pub ahead of print]. Lancet, http://dx.doi.org/10. 1016/S0140-6736(16)00587-0, accessed March 29, 2016.
    • Lancet
    • Fehrenbacher, L.1    Spira, A.2    Ballinger, M.3
  • 240
    • 84907532904 scopus 로고    scopus 로고
    • A phase 1 study of MEDI4736, an anti-PD-L1 antibody, in patients with advanced solid tumors [abstract]
    • Lutzky J, Antonia SJ, Blake-Haskins A, et al. A phase 1 study of MEDI4736, an anti-PD-L1 antibody, in patients with advanced solid tumors [abstract]. J Clin Oncol. 2014;32(suppl):3001.
    • (2014) J Clin Oncol , vol.32 , pp. 3001
    • Lutzky, J.1    Antonia, S.J.2    Blake-Haskins, A.3
  • 241
    • 84938309673 scopus 로고    scopus 로고
    • Phase Ib study of MEDI4736, a programmed cell death ligand-1 (PD-L1) antibody, in combination with tremelimumab, a cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) antibody, in patients (pts) with advanced NSCLC [abstract]
    • Antonia SJ, Goldberg SB, Balmanoukian AS, et al. Phase Ib study of MEDI4736, a programmed cell death ligand-1 (PD-L1) antibody, in combination with tremelimumab, a cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) antibody, in patients (pts) with advanced NSCLC [abstract]. J Clin Oncol. 2015;33(suppl):3014.
    • (2015) J Clin Oncol , vol.33 , pp. 3014
    • Antonia, S.J.1    Goldberg, S.B.2    Balmanoukian, A.S.3
  • 242
    • 84930719096 scopus 로고    scopus 로고
    • Targeting the immune system to treat lung cancer: Rationale and clinical experience
    • Guibert N, Delaunay M, Mazieres J. Targeting the immune system to treat lung cancer: rationale and clinical experience. Ther Adv Respir Dis. 2015;9:105-120.
    • (2015) Ther Adv Respir Dis , vol.9 , pp. 105-120
    • Guibert, N.1    Delaunay, M.2    Mazieres, J.3
  • 243
    • 84949988089 scopus 로고    scopus 로고
    • Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies
    • Naidoo J, Page DB, Li BT, et al. Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies. Ann Oncol. 2015;26:2375-2391.
    • (2015) Ann Oncol , vol.26 , pp. 2375-2391
    • Naidoo, J.1    Page, D.B.2    Li, B.T.3
  • 244
    • 84964031961 scopus 로고    scopus 로고
    • Programmed death ligand 1 immu-nohistochemistry: Friend or foe?
    • Kerr KM, Hirsch FR. Programmed death ligand 1 immu-nohistochemistry: friend or foe? Arch Pathol Lab Med. 2016;140:326-331.
    • (2016) Arch Pathol Lab Med , vol.140 , pp. 326-331
    • Kerr, K.M.1    Hirsch, F.R.2
  • 245
    • 84959537571 scopus 로고    scopus 로고
    • Non-small cell lung cancer PD-L1 and the pathologist
    • Kerr KM, Nicolson MC. Non-small cell lung cancer, PD-L1, and the pathologist. Arch Pathol Lab Med. 2016;140:249-254.
    • (2016) Arch Pathol Lab Med , vol.140 , pp. 249-254
    • Kerr, K.M.1    Nicolson, M.C.2
  • 246
    • 84942867600 scopus 로고    scopus 로고
    • Programmed death-ligand 1 immunohistochemistry in lung cancer: In what state is this art?
    • Kerr KM, Tsao MS, Nicholson AG, et al. Programmed death-ligand 1 immunohistochemistry in lung cancer: in what state is this art? J Thorac Oncol. 2015;10:985-989.
    • (2015) J Thorac Oncol , vol.10 , pp. 985-989
    • Kerr, K.M.1    Tsao, M.S.2    Nicholson, A.G.3
  • 247
    • 84928761118 scopus 로고    scopus 로고
    • Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
    • Rizvi NA, Hellmann MD, Snyder A, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015;348:124-128.
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1    Hellmann, M.D.2    Snyder, A.3
  • 248
    • 84952643180 scopus 로고    scopus 로고
    • The master protocol concept
    • Redman MW, Allegra CJ. The master protocol concept. Semin Oncol. 2015;42:724-730.
    • (2015) Semin Oncol , vol.42 , pp. 724-730
    • Redman, M.W.1    Allegra, C.J.2
  • 249
  • 250
    • 84927606243 scopus 로고    scopus 로고
    • Lung master protocol (Lung-MAP) - A biomarker-driven protocol for accelerating development of therapies for squamous cell lung cancer: SWOG S1400
    • Herbst RS, Gandara DR, Hirsch FR, et al. Lung master protocol (Lung-MAP) - A biomarker-driven protocol for accelerating development of therapies for squamous cell lung cancer: SWOG S1400. Clin Cancer Res. 2015;21:1514-1524.
    • (2015) Clin Cancer Res , vol.21 , pp. 1514-1524
    • Herbst, R.S.1    Gandara, D.R.2    Hirsch, F.R.3
  • 251
    • 85011253100 scopus 로고    scopus 로고
    • National Academies Press Accessed March 11, 2016
    • Levit L, Balogh E, Nass S, et al. Delivering high-quality cancer care: charting a new course for a system in crisis. National Academies Press; 2013. http://iom. nationalacademies.org/Reports/2013/Delivering-High-Quality-Cancer-Care-Charting-a-New-Course-for-a-System-in-Crisis.aspx?utm-sourcefeedburner&utm-medium feed&utm-campaigneed%3A+IomTopicHealthServicesCoverageAndAccess+%28IOM+Topic%3A+Health+Services+ Coverage+and+Access%29. Accessed March 11, 2016.
    • (2013) Delivering High-quality Cancer Care: Charting A New Course for A System in Crisis
    • Levit, L.1    Balogh, E.2    Nass, S.3
  • 252
    • 84891686782 scopus 로고    scopus 로고
    • Delivering high-quality and affordable care throughout the cancer care continuum
    • Shih YC, Ganz PA, Aberle D, et al. Delivering high-quality and affordable care throughout the cancer care continuum. J Clin Oncol. 2013;31:4151-4157.
    • (2013) J Clin Oncol , vol.31 , pp. 4151-4157
    • Shih, Y.C.1    Ganz, P.A.2    Aberle, D.3
  • 253
    • 84969825209 scopus 로고    scopus 로고
    • Toward a comprehensive cancer measure set: Value-based episodes of care
    • May Accessed March 11, 2016
    • Hassett M, Bach P. Toward a comprehensive cancer measure set: value-based episodes of care. Workshop May. 2008;20. https://www.qualityforum. org/Projects/c-d/Cancer-Measure-Set-Value-Based- Episodes-of-Care/Comprehensive-Cancer-Measure- Set--Value-Based-Episodes-of-Care.aspx. Accessed March 11, 2016.
    • (2008) Workshop , vol.20
    • Hassett, M.1    Bach, P.2
  • 254
    • 84899911233 scopus 로고    scopus 로고
    • American Society of Clinical Oncology perspective: Raising the bar for clinical trials by defining clinically meaningful outcomes
    • Ellis LM, Bernstein DS, Voest EE, et al. American Society of Clinical Oncology perspective: raising the bar for clinical trials by defining clinically meaningful outcomes. J Clin Oncol. 2014;32:1277-1280.
    • (2014) J Clin Oncol , vol.32 , pp. 1277-1280
    • Ellis, L.M.1    Bernstein, D.S.2    Voest, E.E.3
  • 255
    • 84940648261 scopus 로고    scopus 로고
    • A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: The European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS)
    • Cherny NI, Sullivan R, Dafni U, et al. A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS). Ann Oncol. 2015;26: 1547-1573.
    • (2015) Ann Oncol , vol.26 , pp. 1547-1573
    • Cherny, N.I.1    Sullivan, R.2    Dafni, U.3
  • 256
    • 84939251874 scopus 로고    scopus 로고
    • American Society of Clinical Oncology statement: A conceptual framework to assess the value of cancer treatment options
    • Schnipper LE, Davidson NE, Wollins DS, et al. American Society of Clinical Oncology statement: a conceptual framework to assess the value of cancer treatment options. J Clin Oncol. 2015;33:2563-2577.
    • (2015) J Clin Oncol , vol.33 , pp. 2563-2577
    • Schnipper, L.E.1    Davidson, N.E.2    Wollins, D.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.