Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: A cohort study

Annals of Internal Medicine

Volumn 157, Issue 11, 2012, Pages 776-784

  Veronesi, Giulia ^a   Maisonneuve, Patrick ^a   Bellomi, Massimo ^a   Rampinelli, Cristiano ^a   Durli, Iara ^a   Bertolotti, Raffaella ^a   Spaggiari, Lorenzo ^a  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER GROWTH; CANCER MORTALITY; CANCER OVERDIAGNOSIS; CANCER RISK; CANCER SCREENING; CANCER SPECIFIC SURVIVAL; CANCER STAGING; CANCER SURVIVAL; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HUMAN; LOW ENERGY RADIATION; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TUMOR VOLUME;

EID: 84870525789     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-157-11-201212040-00005     Document Type: Article

References (45)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61:69-90. [PMID: 21296855]
2. Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowlati A, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006;355:2542-2550. [PMID: 17167137]
3. Beadsmoore CJ, Screaton NJ. Classification, staging and prognosis of lung cancer. Eur J Radiol. 2003;45:8-17. [PMID: 12499060]
4. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM. Natural history of stage I non-small cell lung cancer: implications for early detection. Chest. 2007;132:193-199. [PMID: 17505036]
5. Aberle DR, Adams AM, Berg CD, Black WC, Clapp JD, Fagerstrom RM, et al; National Lung Screening Trial Research Team. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011; 365:395-409. [PMID: 21714641]
6. Diederich S, Thomas M, Semik M, Lenzen H, Roos N, Weber A, et al. Screening for early lung cancer with low-dose spiral computed tomography: results of annual follow-up examinations in asymptomatic smokers. Eur Radiol. 2004;14:691-702. [PMID: 14727146]
7. Henschke CI, McCauley DI, Yankelevitz DF, Naidich DP, McGuinness G, Miettinen OS, et al. Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet. 1999;354:99-105. [PMID: 10408484]
8. Mulshine JL, Sullivan DC. Clinical practice. Lung cancer screening. N Engl J Med. 2005;352:2714-2720. [PMID: 15987920]
9. Sone S, Li F, Yang ZG, Takashima S, Maruyama Y, Hasegawa M, et al. Characteristics of small lung cancers invisible on conventional chest radiography and detected by population based screening using spiral CT. Br J Radiol. 2000; 73:137-145. [PMID: 10884725]
10. Swensen SJ, Jett JR, Hartman TE, Midthun DE, Sloan JA, Sykes AM, et al. Lung cancer screening with CT: Mayo Clinic experience. Radiology. 2003;226: 756-761. [PMID: 12601181]
11. Veronesi G, Bellomi M, Mulshine JL, Pelosi G, Scanagatta P, Paganelli G, et al. Lung cancer screening with low-dose computed tomography: a non-invasive diagnostic protocol for baseline lung nodules. Lung Cancer. 2008;61:340-349. [PMID: 18308420]
12. Veronesi G, Bellomi M, Scanagatta P, Preda L, Rampinelli C, Guarize J, et al. Difficulties encountered managing nodules detected during a computed tomography lung cancer screening program. J Thorac Cardiovasc Surg. 2008; 136:611-617. [PMID: 18805261]
13. van Klaveren RJ, Oudkerk M, Prokop M, Scholten ET, Nackaerts K, Vernhout R, et al. Management of lung nodules detected by volume CT scanning. N Engl J Med. 2009;361:2221-2229. [PMID: 19955524]
14. Welch HG, Black WC. Overdiagnosis in cancer. J Natl Cancer Inst. 2010; 102:605-613. [PMID: 20413742]
15. Zackrisson S, Andersson I, Janzon L, Manjer J, Garne JP. Rate of over-diagnosis of breast cancer 15 years after end of Malmö mammographic screening trial: follow-up study. BMJ. 2006;332:689-692. [PMID: 16517548]
16. Harach HR, Franssila KO, Wasenius VM. Occult papillary carcinoma of the thyroid. A "normal" finding in Finland. A systematic autopsy study. Cancer. 1985;56:531-538. [PMID: 2408737]
17. Berland LL. Incidental extracolonic findings on CT colonography: the impending deluge and its implications. J Am Coll Radiol. 2009;6:14-20. [PMID: 19111266]
18. Fontana RS, Sanderson DR, Woolner LB, Taylor WF, Miller WE, Muhm JR, et al. Screening for lung cancer. A critique of the Mayo Lung Project. Cancer. 1991;67:1155-1164. [PMID: 1991274]
19. Leo F, Nicholson AG, Hansell DM, Corrin B, Pastorino U. Spontaneous regression of large-cell carcinoma of the lung-a rare observation in clinical practice. Thorac Cardiovasc Surg. 1999;47:53-55. [PMID: 10218623]
20. Yankelevitz DF, Kostis WJ, Henschke CI, Heelan RT, Libby DM, Pas-mantier MW, et al. Overdiagnosis in chest radiographic screening for lung carcinoma: frequency. Cancer. 2003;97:1271-1275. [PMID: 12599235]
21. McMahon PM, Kong CY, Johnson BE, Weinstein MC, Weeks JC, Kuntz KM, et al. Estimating long-term effectiveness of lung cancer screening in the Mayo CT screening study. Radiology. 2008;248:278-287. [PMID: 18458247]
22. Henschke CI, Boffetta P, Gorlova O, Yip R, Delancey JO, Foy M. Assessment of lung-cancer mortality reduction from CT Screening. Lung Cancer. 2011;71:328-332. [PMID: 21168236]
23. Veronesi G, Maisonneuve P, Spaggiari L, Rampinelli C, Pelosi G, Preda L, et al. Long-term outcomes of a pilot CT screening for lung cancer. Ecancermedi-calscience. 2010;4:186. [PMID: 22276037]
24. Yankelevitz DF, Reeves AP, Kostis WJ, Zhao B, Henschke CI. Small pulmonary nodules: volumetrically determined growth rates based on CT evaluation. Radiology. 2000;217:251-256. [PMID: 11012453]
25. Pedersen JH, Ashraf H, Dirksen A, Bach K, Hansen H, Toennesen P, et al. The Danish randomized lung cancer CT screening trial- overall design and results of the prevalence round. J Thorac Oncol. 2009;4:608-614. [PMID: 19357536]
26. Baldwin DR, Duffy SW, Wald NJ, Page R, Hansell DM, Field JK. UK Lung Screen (UKLS) nodule management protocol: modelling of a single screen randomised controlled trial of low-dose CT screening for lung cancer. Thorax. 2011;66:308-313. [PMID: 21317179]
27. Maisonneuve P, Bagnardi V, Bellomi M, Spaggiari L, Pelosi G, Rampinelli C, et al. Lung cancer risk prediction to select smokers for screening CT-a model based on the Italian COSMOS trial. Cancer Prev Res (Phila). 2011;4:1778-1789. [PMID: 21813406]
28. Bach PB. Is our natural-history model of lung cancer wrong? Lancet Oncol. 2008;9:693-697. [PMID: 18598934]
29. Lindell RM, Hartman TE, Swensen SJ, Jett JR, Midthun DE, Mandrekar JN. 5-year lung cancer screening experience: growth curves of 18 lung cancers compared to histologic type, CT attenuation, stage, survival, and size. Chest. 2009;136:1586-1595. [PMID: 19581354]
30. Hasegawa M, Sone S, Takashima S, Li F, Yang ZG, Maruyama Y, et al. Growth rate of small lung cancers detected on mass CT screening. Br J Radiol. 2000;73:1252-1259. [PMID: 11205667]
31. Geddes DM. The natural history of lung cancer: a review based on rates of tumour growth. Br J Dis Chest. 1979;73:1-17. [PMID: 435370]
32. Friberg S, Mattson S. On the growth rates of human malignant tumors: implications for medical decision making. J Surg Oncol. 1997;65:284-297. [PMID: 9274795]
33. Usuda K, Saito Y, Sagawa M, Sato M, Kanma K, Takahashi S, et al. Tumor doubling time and prognostic assessment of patients with primary lung cancer. Cancer. 1994;74:2239-2244. [PMID: 7922975]
34. Detterbeck FC, Gibson CJ. Turning gray: the natural history of lung cancer over time. J Thorac Oncol. 2008;3:781-792. [PMID: 18594326]
35. Field JK, Smith RA, Aberle DR, Oudkerk M, Baldwin DR, Yankelevitz D, et al; IASLC CT Screening Workshop 2011 Participants. International Association for the Study of Lung Cancer Computed Tomography Screening Workshop 2011 report. J Thorac Oncol. 2012;7:10-19. [PMID: 22173661]
36. Bianchi F, Nicassio F, Marzi M, Belloni E, Dall'olio V, Bernard L, et al. A serum circulating miRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer. EMBO Mol Med. 2011;3:495-503. [PMID: 21744498]
37. Carpagnano GE, Foschino-Barbaro MP, Spanevello A, Resta O, Carpag-nano F, Mulé G, et al. 3p microsatellite signature in exhaled breath condensate and tumor tissue of patients with lung cancer. Am J Respir Crit Care Med. 2008;177:337-341. [PMID: 17962633]
38. Zhong L, Hidalgo GE, Stromberg AJ, Khattar NH, Jett JR, Hirschowitz EA. Using protein microarray as a diagnostic assay for non-small cell lung cancer. Am J Respir Crit Care Med. 2005;172:1308-1314. [PMID: 16109979]
39. Veronesi G, Maisonneuve P, Pelosi G, Casiraghi M, Agoglia BG, Borri A, et al. Screening-detected lung cancers: is systematic nodal dissection always essential? J Thorac Oncol. 2011;6:525-530. [PMID: 21289523]
40. Fan J, Wang L, Jiang GN, Gao W. Sublobectomy versus lobectomy for stage I non-small-cell lung cancer, a meta-analysis of published studies. Ann Surg Oncol. 2012;19:661-668. [PMID: 21769464]
41. Nakamura K, Saji H, Nakajima R, Okada M, Asamura H, Shibata T, et al. A phase III randomized trial of lobectomy versus limited resection for small-sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L). Jpn J Clin Oncol. 2010;40:271-274. [PMID: 19933688]
42. Veronesi G, Galetta D, Maisonneuve P, Melfi F, Schmid RA, Borri A, et al. Four-arm robotic lobectomy for the treatment of early-stage lung cancer. J Tho-rac Cardiovasc Surg. 2010;140:19-25. [PMID: 20038475]
43. Whitson BA, Groth SS, Duval SJ, Swanson SJ, Maddaus MA. Surgery for early-stage non-small cell lung cancer: a systematic review of the video-assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy. Ann Thorac Surg. 2008;86:2008-2016; Discussion 2016-8. [PMID: 19022040]
44. Altorki N, Lane ME, Bauer T, Lee PC, Guarino MJ, Pass H, et al. Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer. J Clin Oncol. 2010;28: 3131-3137. [PMID: 20516450]
45. Veronesi G, Szabo E, Decensi A, Guerrieri-Gonzaga A, Bellomi M, Radice D, et al. Randomized phase II trial of inhaled budesonide versus placebo in high-risk individuals with CT screen-detected lung nodules. Cancer Prev Res (Phila). 2011;4:34-42. [PMID: 21163939]