Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers

Clinical Cancer Research

Volumn 19, Issue 8, 2013, Pages 2240-2247

  Yu, Helena A ^a   Arcila, Maria E ^a   Rekhtman, Natasha ^a   Sima, Camelia S ^a   Zakowski, Maureen F ^a   Pao, William ^b   Kris, Mark G ^a   Miller, Vincent A ^a   Ladanyi, Marc ^a   Riely, Gregory J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PHOSPHOTRANSFERASE; PROTEIN AKT1; PROTEIN NRAS; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER LOCALIZATION; CANCER RESISTANCE; CANCER SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG BIOPSY; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN DETERMINATION; SURVIVAL RATE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD56; BIOPSY; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; KAPLAN-MEIER ESTIMATE; KI-67 ANTIGEN; LUNG; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-MET; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2;

EID: 84877100240     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-12-2246     Document Type: Article

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