Improving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry

Analytica Chimica Acta

Volumn 930, Issue , 2016, Pages 13-22

  Ranninger, Christina ^a   Schmidt, Lukas E ^a   Rurik, Marc ^b   Limonciel, Alice ^c   Jennings, Paul ^c   Kohlbacher, Oliver ^b,d   Huber, Christian G ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

Data evaluation; Electrospray ionization mass spectrometry; High performance liquid chromatography; Orbitrap; Scan range optimization; Untargeted metabolomics

Indexed keywords

BIOMOLECULES; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; IONS; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; MOLECULAR BIOLOGY; NEGATIVE IONS; POSITIVE IONS; QUALITY CONTROL; SEPARATION; SPECTROMETRY;

DATA EVALUATION; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; METABOLOMICS; ORBITRAP; SCAN RANGE;

FEATURE EXTRACTION;

3 NITROTYROSINE; METHANOL;

ANALYTIC METHOD; ARTICLE; CELL LYSATE; DATA PROCESSING; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY ORBITRAP MASS SPECTROMETRY; HUMAN; HUMAN CELL; IONIZATION; KIDNEY PROXIMAL TUBULE; METABOLOMICS; MOLECULAR SIZE; PRIORITY JOURNAL; QUALITY CONTROL; MASS SPECTROMETRY; PROCEDURES;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MASS SPECTROMETRY; METABOLOMICS;

EID: 84969597484     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2016.05.017     Document Type: Article

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