Selection of a high-affinity WW domain against the extracellular region of VEGF receptor isoform-2 from a combinatorial library using CIS display

Protein Engineering, Design and Selection

Volumn 26, Issue 4, 2013, Pages 307-315

  Patel, Seema ^a   Mathonet, Pascale ^a   Jaulent, Agnes M ^a   Ullman, Christopher G ^a  

^a The Mansion   (United Kingdom)

Author keywords

CIS display; in vitro display; Pin1; scaffold; WW domain

Indexed keywords

COMBINATORIAL LIBRARY; HIGH-AFFINITY BINDERS; IN-VITRO; INTRACELLULAR SIGNALLING; PIN1; PROTEOLYTIC STABILITY; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR; WW DOMAIN;

AMINO ACIDS; PROTEINS; SCAFFOLDS;

SCAFFOLDS (BIOLOGY);

TRYPTOPHAN; VASCULOTROPIN RECEPTOR 2;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMBINATORIAL LIBRARY; CYCLIZATION; DISSOCIATION CONSTANT; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; HYDROGEN BOND; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; AMINO ACIDS; ANGIOGENESIS INHIBITORS; HUMANS; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STABILITY; PROTEOLYSIS; TRYPTOPHAN; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84875686346     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzt003     Document Type: Article

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