Dose-dependent genotoxicity of copper oxide nanoparticles stimulated by reactive oxygen species in human lung epithelial cells

Toxicology and Industrial Health

Volumn 32, Issue 5, 2016, Pages 809-821

  Akhtar, Mohammad Javed ^a   Kumar, Sudhir ^b   Alhadlaq, Hisham A ^a   Alrokayan, Salman A ^a   Abu Salah, Khalid M ^a   Ahamed, Maqusood ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

apoptosis; DNA damage; nanoparticle; Nanotoxicity; oxidative stress

Indexed keywords

COPPER OXIDE NANOPARTICLE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; COPPER; CUPROUS OXIDE; LACTATE DEHYDROGENASE; METAL NANOPARTICLE;

A549 CELL LINE; ARTICLE; CELL CULTURE; CELL STRUCTURE; CELL VIABILITY; COMET ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOSE RESPONSE; EPITHELIUM CELL; FLOW CYTOMETRY; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; MICRONUCLEUS; OXIDATIVE STRESS; TRANSMISSION ELECTRON MICROSCOPY; A-549 CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; LIPID PEROXIDATION; LUNG; METABOLISM;

A549 CELLS; COMET ASSAY; COPPER; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; LUNG; METAL NANOPARTICLES; MICROSCOPY, ELECTRON, TRANSMISSION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84968860899     PISSN: 07482337     EISSN: 14770393     Source Type: Journal    
DOI: 10.1177/0748233713511512     Document Type: Article

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