Protective effect of sulphoraphane against oxidative stress mediated toxicity induced by CuO nanoparticles in mouse embryonic fibroblasts BALB 3T3

Journal of Toxicological Sciences

Volumn 37, Issue 1, 2012, Pages 139-148

  Akhtar, Mohd Javed ^a,b   Ahamed, Maqusood ^c   Fareed, Mohd ^b   Alrokayan, Salman A ^c   Kumar, Sudhir ^a  

^a UNIVERSITY OF LUCKNOW   (India)

^b CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

CuO Nanoparticles; Cytotoxicity; Oxidative stress; Protection; ROS; Sulforaphane

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETYLCYSTEINE; ANTIOXIDANT; COPPER OXIDE; COPPER OXIDE NANOPARTICLE; GLUTATHIONE; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; SULPHORAPHANE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BROCCOLI; CAULIFLOWER; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG MECHANISM; EMBRYO; FIBROBLAST; INFLAMMATION; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS;

BRASSICA OLERACEA VAR. BOTRYTIS; BRASSICA OLERACEA VAR. ITALICA;

EID: 84863166182     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.139     Document Type: Article

References (51)

1. Ahamed, M., Karns, M., Goodson, M., Rowe, J., Hussain, S., Schlager, J. and Hong, Y. (2008): DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells. Toxicol. Appl. Pharmacol., 233, 404-410
2. Ahamed, M., AlSalhi, M.S. and Siddiqui, M.K.J. (2010a): Silver nanoparticle applications and human health. Clin. Chim. Acta, 411, 1841-1848
3. Ahamed, M., Posgai, R., Gorey, T.J., Nielsen, M., Hussain, S. and Rowe, J. (2010b): Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster. Toxicol. Appl. Pharmacol., 242, 263-269
4. Ahamed, M., Siddiqui, M.A., Akhtar, M.J., Ahmad, I., Pant, A.B. and Alhadlaq, H.A. (2010c): Genotoxic potential of copper oxide nanoparticles in human lung epithelial cells. Biochem. Biophys. Res. Commun., 396, 578-583
5. Ahamed, M., Akhtar, M.J., Siddiqui, M.A., Ahmad, J., Musarrat, J., Al-Khedhairy, A.A., AlSalhi, M.S. and Alrokayan, S.A. (2011a): Oxidative stress mediated apoptosis induced by nickel ferrite nanoparticles in cultured A549 cells. Toxicology, 283, 101-108
6. Ahamed, M. (2011b): Toxic response of nickel nanoparticles in human lung epithelial A549 cells. Toxicol. In Vitro, 25, 930-936
7. Ahamed, M., Akhtar, M.J., Raja, M., Ahmad, I., Siddiqui, M.K.J., AlSalhi, M.S. and Alrokayan, S.A. (2011c): ZnO nanorodinduced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: role of oxidative stress. Nanomedicine, 7, 904-913
8. Akhtar, M.J., Ahamed, M., Kumar, S., Siddiqui, S., Patil, G., Ashquin, M. and Ahmad, I. (2010a): Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells. Toxicology, 276, 95-102
9. Akhtar, M.J., Kumar, S., Murthy, R.C., Ashquin, M., Khan, M.I., Patil, G. and Ahmad, I. (2010b): The primary role of iron-mediated lipid peroxidation in the differential cytotoxicity caused by two varieties of talc nanoparticles on A549 cells and lipid peroxidation inhibitory effect exerted by ascorbic acid. Toxicol. In Vitro, 24, 1139-1147
10. Bai, W., Zhang, Z., Tian, W., He, X., Ma, Y., Zhao, Y. and Chai, Z. (2010): Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism. J. Nanopart. Res., 12, 1645-1654
11. Banning, A., Deubel, S., Kluth, D. and Zhou Z. (2005): The GI-GPx gene is a target for Nrf2. Mol. Cell Biol., 25, 4914-4923
12. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254
13. Conaway, C.C., Wang, C.X., Pittman, B. and Yang, Y.M. (2005): Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice. Cancer Res., 65, 8548-8557
14. Cornblatt, B.S., Ye, L., Dinkova-Kostova, A.T., Erb, M., Fahey, J.W., Singh, N.K., Chen, M.S., Stierer, T., Garrett-Mayer, E., Argani, P., Davidson, N.E., Talalay, P., Kensler, T.W. and Visvanathan, K. (2007): Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast. Carcinogenesis, 28, 1485-1490
15. Dinkova-Kostova, A.T., Fahey, J.W., Wade, K.L. and Jenkins, S.N. (2007): Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol. Biomarkers Prev., 16, 847-851
16. Dinkova-Kostova, A.T., Jenkins, S.N., Fahey, J.W., Ye, L., Wehage, S.L., Liby, K.T., Stephenson, K.K., Wade, K.L. and Talalay, P. (2006): Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts. Cancer Lett., 240, 243-252
17. Fahey, J.W. and Talalay, P. (1999): Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes. Food Chem. Toxicol., 37, 973-979
18. Fahmy, B. and Cormier, S.A. (2009): Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells. Toxicol. In Vitro, 23, 1365-1371
19. Gao, X., Dinkova-Kostova, A.T. and Talalay, P. (2001): Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane. Proc. Natl. Acad. Sci. USA, 98, 15221-15226
20. Gao, X. and Talalay, P. (2004): Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc. Natl. Acad. Sci. USA, 101, 10446-10451
21. Goldberg, D.M. and Spooner, R.J. (1983): Glutathione reductase. In: Bergmeyer, H.U. (Ed.), Methods of Enzymatic Analysis. Verlag Chemie, Deerfield Beach, 1258-1265
22. Griffitt, R.J., Weil, R., Hyndman, K.A. and Denslow, N.D. (2007): Exposure to copper nanoparticles causes gill injury and acute lethality in zebrafish (Danio rerio). Environ. Sci. Technol., 41, 8178-8186
23. Hansen, M.B., Nielsen, S.E. and Berg, K. (1989): Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immun. Methods, 119, 203-210
24. Hissin, P.J. and Hilf, R. (1976): A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem., 74, 214-226
25. Huang, Y.-W., Wu, C-h and Aronstam, R.S. (2010): Toxicity of transition metal oxide nanoparticles: recent insights from in vitro studies. Materials, 3, 4842-4859
26. Jiang, Z.Q., Chen, C., Yang, B. and Hebbar, V. (2003): Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers. Life Sci., 72, 2243-2253
27. Juge, N., Mithen, R.F. and Traka, M. (2007): Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell. Mol. Life Sci., 64, 1105-1127
28. Kahru, A. and Dubourguier, H.C. (2010): From ecotoxicology to nanoecotoxicology. Toxicology, 269, 105-119
29. Karthikeyan, N.R., Philip, J. and Raj, B. (2008): Effect of clustering on the thermal conductivity of nanofluids. Mater. Chem. Phys., 109, 50-55
30. Keck, A.S. and Finley, J.W. (2006): Aqueous extracts of selenium-fertilized broccoli increase selenoprotein activity and inhibit DNA single-strand breaks, but decrease the activity of quinone reductase in Hepa 1c1c7 cells. Food Chem. Toxicol., 44, 695-703
31. Kensle, T.W., Chen, J.G., Egner, P.A., Fahey, J.W., Jacobson, L.P., Stephenson, K.K., Ye, L., Coady, J.L., Wang, J.B., Wu, Y., Sun, Y., Zhang, Q.N., Zhang, B.C., Zhu, Y.R., Qian, G.S., Carmella, S.G., Hecht, S.S., Benning, L., Gange, S.J., Groopman, J.D. and Talalay, P.(2005): Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidem. Biomark, 14, 2605-2613
32. Kong, L., Chen, G.D., Zhou, X., McGinnis, J.F., Li, F. and Cao, W. (2009): Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane. Neurochem. Int., 54, 172-179
33. Liu, H., Dinkova-Kostova, A.T. and Talalay, P. (2008): Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles. Proc. Natl. Acad. Sci. USA, 105, 15926-15931
34. Meister, A. and Anderson, M.E. (1983): Glutathione. Annu. Rev. Biochem., 52, 711-760
35. Mosmann, T. (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immun. Methods, 65, 55-63
36. Nel, A., Xia, T., Madler, L. and Li, N. (2006): Toxic potential of materials at the nanolevel. Science, 311, 622-627
37. Ohkawa, H., Ohisi, N. and Yagi, Y. (1979): Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358
38. Patterson, A.L. (1939): The Scherrer formula for X-ray particle size determination. Phys. Rev., 56, 978-982
39. Ritz, S.A., Wan, J. and Diaz-Sanchez, D. (2007): Sulforaphane-stimulated phase II enzyme induction inhibits cytokine produc-tion by airway epithelial cells stimulated with diesel extract. Am. J. Physiol. Lung Cell. Mol. Physiol., 292, L33-L39.
40. Sharma, V., Shukla, R.K., Saxena, N., Parmar, D., Das, M. and Dhawan, A. (2009): DNA damaging potential of zinc oxide nanoparticles in human epidermal cells. Toxicol. Lett., 185, 211-218
41. Shende, R., Subramanian, S., Hasan, S. and Apperson, S. (2008): Nanoenergetic composites of CuO nanorods, nanowires, and Alnanoparticles, Propell. Explos. Pyrot., 33, 122-130
42. Shimizu, M., Hochadel, J.F. and Waalkes, M.P. (1997): Effects of glutathione depletion on cadmium-induced metallothionein synthesis, cytotoxicity, and proto-oncogene activation in cultured rat myoblasts. J. Toxicol. Environ. Health, 51, 609-621
43. Song, K.X., Zhou, J.H., Bao, J.C., Feng, Y.Y. (2008): Photocatalytic activity of (copper, nitrogen)-codoped titanium dioxide nanoparticles. J. Am. Ceram. Soc., 91, 1369-1371
44. Surh, Y.J. (2003): Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer, 3, 768-780
45. Talalay, P., Fahey, J.W., Healy, Z.R., Wehage, S.L., Benedict, A.L., Min, C. and Dinkova-Kostova, A.T. (2007): Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation. Proc. Natl. Acad. Sci. USA, 104, 17500-17505
46. Talalay, P. and Fahey, J.W. (2001): Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism. J. Nutr., 131, 3027S-3033S.
47. Wang, H. and Joseph J.A. (1999): Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic. Biol. Med., 27, 612-616
48. Welder, A.A., Grant, R., Bradlaw, J. and Acosta, D. (1991): A primary culture system of adult rat heart cells for the study of toxicologic agents. In Vitro Cell. Dev. Biol., 27, 921-926
49. Zhang, Y., Li, J. and Tang, L. (2005): Cancer-preventive isothiocyanates: dichotomous modulators of oxidative stress. Free Radic. Biol. Med., 38, 70-77
50. Zhu, H., Han, D., Meng, Z., Wu, D. and Zhang, C. (2011): Preparation and thermal conductivity of CuO nanofluid via a wet chemical method. Nanoscale Res. Lett., 6, 181.
51. Zhu, M., Zhang, Y., Cooper, S., Sikorski, E., Rohwer, J. and Bowden, G.T. (2004): Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism. Mol. Carcin., 41, 179-186.