Mitochondrial oxidative stress-induced epigenetic modifications in pancreatic epithelial cells

International Journal of Toxicology

Volumn 33, Issue 2, 2014, Pages 116-129

  Mishra, Pradyumna Kumar ^a,b,c   Raghuram, Gorantla Venkata ^a,b,c   Jain, Deepika ^a,b,c   Jain, Subodh Kumar ^a   Khare, Naveen Kumar ^b,c   Pathak, Neelam ^c  

^a DR H S GOUR UNIVERSITY   (India)

^b TATA MEMORIAL HOSPITAL   (India)

^c BHOPAL MEMORIAL HOSPITAL AND RESEARCH CENTRE   (India)

Author keywords

DNA methylation; histone modifications; methyl isocyanate; miRNA; pancreatic cancer

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CARBAMIC ACID DERIVATIVE; CASPASE 3; GLUTATHIONE REDUCTASE; HISTONE H2AX; HISTONE H3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; METHYL ISOCYANATE; MICRORNA; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; N SUCCINIMIDYL N METHYLCARBAMIC ACID; OXYGEN RADICAL; PROTEIN P16; SMAD4 PROTEIN; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CPG ISLAND; CYTOKINE RELEASE; CYTOKINE RESPONSE; DNA DAMAGE; DNA METHYLATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIGENETICS; EPITHELIUM CELL; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; HISTONE PHOSPHORYLATION; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MITOCHONDRIAL RESPIRATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PANCREAS CANCER; PANCREAS CELL; PANCREAS DUCT; PANCREATIC DUCTAL EPITHELIAL CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RESPIRATORY CHAIN; WESTERN BLOTTING;

DNA METHYLATION; HISTONE MODIFICATIONS; METHYL ISOCYANATE; MIRNA; PANCREATIC CANCER;

ANTIOXIDANTS; APOPTOSIS; CELL LINE; CYTOKINES; DNA DAMAGE; EPIGENESIS, GENETIC; EPITHELIAL CELLS; HUMANS; MICRORNAS; MITOCHONDRIA; OXIDATIVE STRESS; PANCREAS; REACTIVE OXYGEN SPECIES; SMAD4 PROTEIN;

EID: 84898987305     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581814524064     Document Type: Article

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