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Volumn 11, Issue 5, 2016, Pages 379-393

Evaluating influenza vaccines: Progress and perspectives

Author keywords

influenza viruses; new technologies; novel antigens and adjuvants; seasonal and pandemic vaccines; universal influenza vaccine

Indexed keywords

INFLUENZA VACCINE; PANDEMIC VACCINE; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS VACCINE;

EID: 84966706719     PISSN: 17460794     EISSN: 17460808     Source Type: Journal    
DOI: 10.2217/fvl-2016-0012     Document Type: Review
Times cited : (13)

References (160)
  • 2
    • 84863230485 scopus 로고    scopus 로고
    • A distinct lineage of influenza A virus from bats
    • Tong S, Li Y, Rivailler P et al. A distinct lineage of influenza A virus from bats. Proc. Natl Acad. Sci. USA 109(11), 4269-4274 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.11 , pp. 4269-4274
    • Tong, S.1    Li, Y.2    Rivailler, P.3
  • 3
    • 84887290174 scopus 로고    scopus 로고
    • New world bats harbor diverse influenza a viruses
    • Tong S, Zhu X, Li Y et al. New world bats harbor diverse influenza a viruses. PLoS Pathog. 9(10), e1003657-e1003657 (2013).
    • (2013) PLoS Pathog. , vol.9 , Issue.10 , pp. e1003657-e1003657
    • Tong, S.1    Zhu, X.2    Li, Y.3
  • 4
    • 84907686123 scopus 로고    scopus 로고
    • Antiviral activity of novel oseltamivir derivatives against some influenza virus strains
    • Kocik J, Kołodziej M, Joniec J, Kwiatek M, Bartoszcze M. Antiviral activity of novel oseltamivir derivatives against some influenza virus strains. Acta Biochim. Pol. 61(3), 509-513 (2014).
    • (2014) Acta Biochim. Pol. , vol.61 , Issue.3 , pp. 509-513
    • Kocik, J.1    Kołodziej, M.2    Joniec, J.3    Kwiatek, M.4    Bartoszcze, M.5
  • 5
    • 0001387044 scopus 로고    scopus 로고
    • Orthomyxoviruses
    • (3rd Edition). Fields BN, Knipe DM, Howley PM (Eds). Lippincott-Raven Publishers, PA, USA
    • Murphy BR, Webster RG. Orthomyxoviruses. In: Field's Virology (3rd Edition). Fields BN, Knipe DM, Howley PM (Eds). Lippincott-Raven Publishers, PA, USA, 1397-1445 (1996).
    • (1996) Field's Virology , pp. 1397-1445
    • Murphy, B.R.1    Webster, R.G.2
  • 6
    • 36148972069 scopus 로고    scopus 로고
    • Influenza: The virus and prophylaxis with inactivated influenza vaccine in 'at risk' groups, including COPD patients
    • Hovden AO, Cox RJ, Haaheim LR. Influenza: The virus and prophylaxis with inactivated influenza vaccine in 'at risk' groups, including COPD patients. Int. J. Chron. Obstruct. Pulmon. Dis. 2(3), 229-240 (2007).
    • (2007) Int. J. Chron. Obstruct. Pulmon. Dis. , vol.2 , Issue.3 , pp. 229-240
    • Hovden, A.O.1    Cox, R.J.2    Haaheim, L.R.3
  • 9
    • 84951310130 scopus 로고    scopus 로고
    • Quantifying the risk of pandemic influenza virus evolution by mutation and re-assortment
    • Reperant LA, Grenfell BT, Osterhaus AD. Quantifying the risk of pandemic influenza virus evolution by mutation and re-assortment. Vaccine 33(49), 6955-6966 (2015).
    • (2015) Vaccine , vol.33 , Issue.49 , pp. 6955-6966
    • Reperant, L.A.1    Grenfell, B.T.2    Osterhaus, A.D.3
  • 10
    • 84942614642 scopus 로고    scopus 로고
    • Refining the approach to vaccines against influenza A viruses with pandemic potential
    • Czako R, Subbarao K. Refining the approach to vaccines against influenza A viruses with pandemic potential. Future Virol. 10(9), 1033-1047 (2015).
    • (2015) Future Virol. , vol.10 , Issue.9 , pp. 1033-1047
    • Czako, R.1    Subbarao, K.2
  • 12
    • 57649237732 scopus 로고    scopus 로고
    • Influenza vaccination and risk of community-acquired pneumonia
    • Thijs C, Knottnerus A. Influenza vaccination and risk of community-acquired pneumonia. Lancet 372, 2112-2113 (2008).
    • (2008) Lancet , vol.372 , pp. 2112-2113
    • Thijs, C.1    Knottnerus, A.2
  • 13
    • 58549106752 scopus 로고    scopus 로고
    • Reduced reaction frequencies with repeated inactivated or live-attenuated influenza vaccination
    • Ohmit SE, Gross J, Victor JC, Monto AS. Reduced reaction frequencies with repeated inactivated or live-attenuated influenza vaccination. Vaccine 27, 1050-1054 (2009).
    • (2009) Vaccine , vol.27 , pp. 1050-1054
    • Ohmit, S.E.1    Gross, J.2    Victor, J.C.3    Monto, A.S.4
  • 14
    • 84912523785 scopus 로고    scopus 로고
    • Molecular markers of influenza B lineages and clades
    • Arvia R, Corcioli F, Pierucci F, Azzi A. Molecular markers of influenza B lineages and clades. Viruses 6(11), 4437-4446 (2014).
    • (2014) Viruses , vol.6 , Issue.11 , pp. 4437-4446
    • Arvia, R.1    Corcioli, F.2    Pierucci, F.3    Azzi, A.4
  • 15
    • 84952875558 scopus 로고    scopus 로고
    • Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine
    • Cox F, Saeland E, Baart M et al. Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine. Virol. J. 12, 210 (2015).
    • (2015) Virol. J. , vol.12 , pp. 210
    • Cox, F.1    Saeland, E.2    Baart, M.3
  • 16
    • 0031820637 scopus 로고    scopus 로고
    • Molecular basis for the generation in pigs of influenza A viruses with pandemic potential
    • Ito T, Couceiro JN, Kelm S et al. Molecular basis for the generation in pigs of influenza A viruses with pandemic potential. J. Virol. 72(9), 7367-7373 (1998).
    • (1998) J. Virol. , vol.72 , Issue.9 , pp. 7367-7373
    • Ito, T.1    Couceiro, J.N.2    Kelm, S.3
  • 17
    • 67449136751 scopus 로고    scopus 로고
    • The pig as a mixing vessel for influenza viruses: Human and veterinaryimplications
    • Ma W, Kahn RE, Richt JA. The pig as a mixing vessel for influenza viruses: human and veterinaryimplications. J. Mol. Genet. Med. 3(1), 158-166 (2008).
    • (2008) J. Mol. Genet. Med. , vol.3 , Issue.1 , pp. 158-166
    • Ma, W.1    Kahn, R.E.2    Richt, J.A.3
  • 18
    • 77956273847 scopus 로고    scopus 로고
    • Estimates of deaths associated with seasonal influenza-United States, 1976-2007
    • Centers for Disease Control and Prevention. Estimates of deaths associated with seasonal influenza-United States, 1976-2007. MMWR Morb. Mortal. Wkly Rep. 59, 1057-1062 (2010).
    • (2010) MMWR Morb. Mortal. Wkly Rep. , vol.59 , pp. 1057-1062
    • Centers for Disease Control and Prevention1
  • 19
    • 79952031057 scopus 로고    scopus 로고
    • Seasonal influenza epidemiology in sub-Saharan Africa: A systematic review
    • Gessner BD, Shindo N, Briand S. Seasonal influenza epidemiology in sub-Saharan Africa: A systematic review. Lancet Infect. Dis. 11, 223-235 (2011).
    • (2011) Lancet Infect. Dis. , vol.11 , pp. 223-235
    • Gessner, B.D.1    Shindo, N.2    Briand, S.3
  • 20
    • 82755189828 scopus 로고    scopus 로고
    • Global burden of respiratory infections due to seasonal influenza in young children: A systematic review and meta-analysis
    • Nair H, Brooks WA, Katz M et al. Global burden of respiratory infections due to seasonal influenza in young children: A systematic review and meta-analysis. Lancet 378, 1917-1930 (2011).
    • (2011) Lancet , vol.378 , pp. 1917-1930
    • Nair, H.1    Brooks, W.A.2    Katz, M.3
  • 21
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010
    • Lozano R, Naghavi M, Foreman K et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2095-2128 (2012).
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 22
    • 84870020404 scopus 로고    scopus 로고
    • Influenza surveillance in 15 countries in Africa, 2006-2010
    • Radin JM, Katz MA, Tempia S et al. Influenza surveillance in 15 countries in Africa, 2006-2010. J. Infect. Dis. 206(Suppl. 1), S14-S21 (2012).
    • (2012) J. Infect. Dis. , vol.206 , pp. S14-S21
    • Radin, J.M.1    Katz, M.A.2    Tempia, S.3
  • 23
    • 0004251988 scopus 로고    scopus 로고
    • International Epidemiological Association, New York, NY, USA
    • Last JM. A Dictionary of Epidemiology. International Epidemiological Association, New York, NY, USA (2001).
    • (2001) A Dictionary of Epidemiology
    • Last, J.M.1
  • 24
    • 0034796387 scopus 로고    scopus 로고
    • A history of influenza
    • Potter CW. A history of influenza. J. Appl. Microbiol. 91, 572-579 (2001).
    • (2001) J. Appl. Microbiol. , vol.91 , pp. 572-579
    • Potter, C.W.1
  • 26
    • 84857050827 scopus 로고    scopus 로고
    • Improving influenza vaccine virus selection. Report of a WHO informal consultation
    • WHO Writing Group. Improving influenza vaccine virus selection. Report of a WHO informal consultation. Influ. Other Respir. Viruses 6(2), 142-152 (2012).
    • (2012) Influ. Other Respir. Viruses , vol.6 , Issue.2 , pp. 142-152
    • WHO Writing Group1
  • 27
    • 84857050827 scopus 로고    scopus 로고
    • Improving influenza vaccine virus selection: Report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010
    • Ampofo WK, Baylor N, Cobey S et al. Improving influenza vaccine virus selection: report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010. Influenza Other Respir. Viruses 6(2), e141-e145 (2012).
    • (2012) Influenza Other Respir. Viruses , vol.6 , Issue.2 , pp. e141-e145
    • Ampofo, W.K.1    Baylor, N.2    Cobey, S.3
  • 28
    • 84939569063 scopus 로고    scopus 로고
    • Strengthening the influenza vaccine virus selection and development process: Report of the 3rd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at WHO headquarters, Geneva, Switzerland, 1-3 April 2014
    • Ampofo WK, Azziz-Baumgartner E, Bashir U et al. Strengthening the influenza vaccine virus selection and development process: Report of the 3rd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at WHO headquarters, Geneva, Switzerland, 1-3 April 2014. Vaccine 33(36), 4368-4382 (2015).
    • (2015) Vaccine , vol.33 , Issue.36 , pp. 4368-4382
    • Ampofo, W.K.1    Azziz-Baumgartner, E.2    Bashir, U.3
  • 29
    • 81555228705 scopus 로고    scopus 로고
    • Prospects for controlling future pandemics of influenza
    • Robertson JS, Inglis SC. Prospects for controlling future pandemics of influenza. Virus Res. 162(1-2): 39-46 (2011).
    • (2011) Virus Res. , vol.162 , Issue.1-2 , pp. 39-46
    • Robertson, J.S.1    Inglis, S.C.2
  • 30
    • 58849133433 scopus 로고    scopus 로고
    • Using surveillance to evaluate influenza vaccine effectiveness
    • Jackson LA. Using surveillance to evaluate influenza vaccine effectiveness. J. Infect. Dis. 199(2), 155-158 (2009).
    • (2009) J. Infect. Dis. , vol.199 , Issue.2 , pp. 155-158
    • Jackson, L.A.1
  • 31
    • 84925883384 scopus 로고    scopus 로고
    • Options and obstacles for designing a universal influenza vaccine
    • Jang YH, Seong BL. Options and obstacles for designing a universal influenza vaccine. Viruses 6(8), 3159-3180 (2014).
    • (2014) Viruses , vol.6 , Issue.8 , pp. 3159-3180
    • Jang, Y.H.1    Seong, B.L.2
  • 32
    • 84951567527 scopus 로고    scopus 로고
    • Prospects for broadly protective influenza vaccines
    • Treanor JJ. Prospects for broadly protective influenza vaccines. Am. J. Prev. Med. 49(6 Suppl. 4), S355-S363 (2015).
    • (2015) Am. J. Prev. Med. , vol.49 , Issue.6 , pp. S355-S363
    • Treanor, J.J.1
  • 33
    • 84924308737 scopus 로고    scopus 로고
    • Prospects of HA-based universal influenza vaccine
    • Hashem AM. Prospects of HA-based universal influenza vaccine. Biomed. Res. Int. 2015, 414637 (2015).
    • (2015) Biomed. Res. Int. , vol.2015 , pp. 414637
    • Hashem, A.M.1
  • 35
    • 0025895936 scopus 로고
    • Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel
    • al-Mazrou A, Scheifele DW, Soong T, Bjornson G. Comparison of adverse reactions to whole-virion and split-virion influenza vaccines in hospital personnel. Can. Med. Assoc. J. 145(3), 213-218 (1991).
    • (1991) Can. Med. Assoc. J. , vol.145 , Issue.3 , pp. 213-218
    • Al-Mazrou, A.1    Scheifele, D.W.2    Soong, T.3    Bjornson, G.4
  • 37
    • 83155164584 scopus 로고    scopus 로고
    • Fluzone(R) intradermal vaccine: A promising new chance to increase the acceptability of influenza vaccination in adults
    • Ansaldi F, de Florentiis D, Durando P, Icardi G. Fluzone(R) intradermal vaccine: A promising new chance to increase the acceptability of influenza vaccination in adults. Expert Rev. Vaccines 11(1), 17-25 (2012).
    • (2012) Expert Rev. Vaccines , vol.11 , Issue.1 , pp. 17-25
    • Ansaldi, F.1    De Florentiis, D.2    Durando, P.3    Icardi, G.4
  • 38
    • 84930939699 scopus 로고    scopus 로고
    • Current and next generation influenza vaccines: Formulation and production strategies
    • Soema PC, Kompier R, Amorij JP, Kersten GF. Current and next generation influenza vaccines: formulation and production strategies. Eur. J. Pharm. Biopharm. 94, 251-263 (2015).
    • (2015) Eur. J. Pharm. Biopharm. , vol.94 , pp. 251-263
    • Soema, P.C.1    Kompier, R.2    Amorij, J.P.3    Kersten, G.F.4
  • 39
    • 79951812398 scopus 로고    scopus 로고
    • Evaluation of the safety, reactogenicity and immunogenicity of FluBlok(R) trivalent recombinant baculovirusexpressed hemagglutinin influenza vaccine administered intramuscularly to healthy adults 50-64 years of age
    • Baxter R, Patriarca PA, Ensor K, Izikson R, Goldenthal KL, Cox MM. Evaluation of the safety, reactogenicity and immunogenicity of FluBlok(R) trivalent recombinant baculovirusexpressed hemagglutinin influenza vaccine administered intramuscularly to healthy adults 50-64 years of age. Vaccine 29(12), 2272-2278 (2011).
    • (2011) Vaccine , vol.29 , Issue.12 , pp. 2272-2278
    • Baxter, R.1    Patriarca, P.A.2    Ensor, K.3    Izikson, R.4    Goldenthal, K.L.5    Cox, M.M.6
  • 40
    • 70350574083 scopus 로고    scopus 로고
    • Evaluation of the safety, reactogenicity and immunogenicity of FluBlok trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy children aged 6-59 months
    • King JC Jr, Cox MM, Reisinger K, Hedrick J, Graham I, Patriarca P. Evaluation of the safety, reactogenicity and immunogenicity of FluBlok trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy children aged 6-59 months. Vaccine 27(47), 6589-6594 (2009).
    • (2009) Vaccine , vol.27 , Issue.47 , pp. 6589-6594
    • King, J.C.1    Cox, M.M.2    Reisinger, K.3    Hedrick, J.4    Graham, I.5    Patriarca, P.6
  • 41
    • 0031930630 scopus 로고    scopus 로고
    • Comparison of serology and reactogenicity between influenza subunit vaccines and whole virus or split vaccines: A review and metaanalysis of the literature
    • Beyer WE, Palache AM, Osterhaus AD. Comparison of serology and reactogenicity between influenza subunit vaccines and whole virus or split vaccines: A review and metaanalysis of the literature. Clin. Drug Investigat. 15(1), 1-12 (1998).
    • (1998) Clin. Drug Investigat. , vol.15 , Issue.1 , pp. 1-12
    • Beyer, W.E.1    Palache, A.M.2    Osterhaus, A.D.3
  • 42
    • 79960555692 scopus 로고    scopus 로고
    • Immunogenicity and safety of inactivated influenza vaccines in primed populations: A systematic literature review and meta-analysis
    • Beyer WE, Nauta JJ, Palache AM, Giezeman KM, Osterhaus AD. Immunogenicity and safety of inactivated influenza vaccines in primed populations: A systematic literature review and meta-analysis. Vaccine 29(34), 5785-5792 (2011).
    • (2011) Vaccine , vol.29 , Issue.34 , pp. 5785-5792
    • Beyer, W.E.1    Nauta, J.J.2    Palache, A.M.3    Giezeman, K.M.4    Osterhaus, A.D.5
  • 43
    • 80052015820 scopus 로고    scopus 로고
    • Live attenuated influenza vaccine (FluMist[R]; Fluenz): A review of its use in the prevention of seasonal influenza in children and adults
    • Carter NJ, Curran MP. Live attenuated influenza vaccine (FluMist[R]; Fluenz): A review of its use in the prevention of seasonal influenza in children and adults. Drugs 71(12), 1591-1622 (2011).
    • (2011) Drugs , vol.71 , Issue.12 , pp. 1591-1622
    • Carter, N.J.1    Curran, M.P.2
  • 44
    • 0033913482 scopus 로고    scopus 로고
    • Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine
    • Belshe RB, Gruber WC, Mendelman PM et al. Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. J. Pediatr. 136(2), 168-175 (2000).
    • (2000) J. Pediatr. , vol.136 , Issue.2 , pp. 168-175
    • Belshe, R.B.1    Gruber, W.C.2    Mendelman, P.M.3
  • 45
    • 84862026523 scopus 로고    scopus 로고
    • Adaptive pathways of zoonotic influenza viruses: From exposure to establishment in humans
    • Reperant LA, Kuiken T, Osterhaus AD. Adaptive pathways of zoonotic influenza viruses: from exposure to establishment in humans. Vaccine 30(30), 4419-4434 (2012).
    • (2012) Vaccine , vol.30 , Issue.30 , pp. 4419-4434
    • Reperant, L.A.1    Kuiken, T.2    Osterhaus, A.D.3
  • 46
    • 84862610867 scopus 로고    scopus 로고
    • The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host
    • Russell CA, Fonville JM, Brown AE et al. The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host. Science 336(6088), 1541-1547 (2012).
    • (2012) Science , vol.336 , Issue.6088 , pp. 1541-1547
    • Russell, C.A.1    Fonville, J.M.2    Brown, A.E.3
  • 47
    • 66149130765 scopus 로고    scopus 로고
    • Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus
    • Sorrell EM, Wan H, Araya Y, Song H, Perez DR. Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus. Proc. Natl Acad. Sci. USA 106(18), 7565-7570 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.18 , pp. 7565-7570
    • Sorrell, E.M.1    Wan, H.2    Araya, Y.3    Song, H.4    Perez, D.R.5
  • 48
    • 84861394598 scopus 로고    scopus 로고
    • Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
    • Imai K, Nakamura K, Mase M, Tsukamoto K, Imada T, Yamaguchi S. Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature 486(7403), 420-428 (2012).
    • (2012) Nature , vol.486 , Issue.7403 , pp. 420-428
    • Imai, K.1    Nakamura, K.2    Mase, M.3    Tsukamoto, K.4    Imada, T.5    Yamaguchi, S.6
  • 49
    • 84879256682 scopus 로고    scopus 로고
    • H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in Guinea pigs by respiratory droplet
    • Zhang Y, Zhang Q, Kong H et al. H5N1 hybrid viruses bearing 2009/H1N1 virus genes transmit in guinea pigs by respiratory droplet. Science 340(6139), 1459-1463 (2013).
    • (2013) Science , vol.340 , Issue.6139 , pp. 1459-1463
    • Zhang, Y.1    Zhang, Q.2    Kong, H.3
  • 50
    • 84890867459 scopus 로고    scopus 로고
    • Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model
    • Kimble JB, Angel M, Wan H, Sutton TC, Finch C, Perez DR. Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model. J. Virol. 88, 66-71 (2014).
    • (2014) J. Virol. , vol.88 , pp. 66-71
    • Kimble, J.B.1    Angel, M.2    Wan, H.3    Sutton, T.C.4    Finch, C.5    Perez, D.R.6
  • 51
    • 84862618108 scopus 로고    scopus 로고
    • Airborne transmission of influenza A/H5N1 virus between ferrets
    • Herfst S, Schrauwen EJ, Linster M et al. Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336(6088), 1534-1541 (2012).
    • (2012) Science , vol.336 , Issue.6088 , pp. 1534-1541
    • Herfst, S.1    Schrauwen, E.J.2    Linster, M.3
  • 52
    • 84880713109 scopus 로고    scopus 로고
    • H7N9 influenza viruses are transmissible in ferrets by respiratory droplet
    • Zhang Q, Shi J, Deng G et al. H7N9 influenza viruses are transmissible in ferrets by respiratory droplet. Science 341(6144), 410-414 (2013).
    • (2013) Science , vol.341 , Issue.6144 , pp. 410-414
    • Zhang, Q.1    Shi, J.2    Deng, G.3
  • 53
    • 84898662125 scopus 로고    scopus 로고
    • Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus
    • Linster M, van Boheemen S, de Graaf M et al. Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus. Cell 157(2), 329-339 (2014).
    • (2014) Cell , vol.157 , Issue.2 , pp. 329-339
    • Linster, M.1    Van Boheemen, S.2    De Graaf, M.3
  • 54
    • 84901291255 scopus 로고    scopus 로고
    • Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets
    • Sutton TC, Finch C, Shao H et al. Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets. J. Virol. 88(12), 6623-6666 (2014).
    • (2014) J. Virol. , vol.88 , Issue.12 , pp. 6623-6666
    • Sutton, T.C.1    Finch, C.2    Shao, H.3
  • 55
    • 84947201563 scopus 로고    scopus 로고
    • New small-molecule drug design strategies for fighting resistant influenza A
    • Shen Z, Lou K, Wang W. New small-molecule drug design strategies for fighting resistant influenza A. Acta Pharm. Sin. B 5(5), 419-430 (2015).
    • (2015) Acta Pharm. Sin. B , vol.5 , Issue.5 , pp. 419-430
    • Shen, Z.1    Lou, K.2    Wang, W.3
  • 57
    • 84877785371 scopus 로고    scopus 로고
    • Human infection with a novel avian-origin influenza A (H7N9) virus
    • Gao R, Cao B, Hu Y et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N. Engl. J. Med. 368(20), 1888-1897 (2013).
    • (2013) N. Engl. J. Med. , vol.368 , Issue.20 , pp. 1888-1897
    • Gao, R.1    Cao, B.2    Hu, Y.3
  • 58
    • 67650407532 scopus 로고    scopus 로고
    • Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
    • Garten RJ, Davis CT, Russell CA et al. Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science 325, 197-201 (2009).
    • (2009) Science , vol.325 , pp. 197-201
    • Garten, R.J.1    Davis, C.T.2    Russell, C.A.3
  • 59
    • 80053375600 scopus 로고    scopus 로고
    • Influenza virus vaccines: Lessons from the 2009 H1N1 pandemic
    • Broadbent AJ, Subbarao K. Influenza virus vaccines: lessons from the 2009 H1N1 pandemic. Curr. Opin. Virol. 1, 254-262 (2011).
    • (2011) Curr. Opin. Virol. , vol.1 , pp. 254-262
    • Broadbent, A.J.1    Subbarao, K.2
  • 60
    • 84861872090 scopus 로고    scopus 로고
    • Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells
    • Li GM, Chiu C, Wrammert J et al. Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells. Proc. Natl Acad. Sci. USA 109(23), 9047-9052 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.23 , pp. 9047-9052
    • Li, G.M.1    Chiu, C.2    Wrammert, J.3
  • 61
    • 84952637482 scopus 로고    scopus 로고
    • Persistence and avidity maturation of antibodies to A(H1N1)pdm09 in healthcare workers following repeated annual vaccinations
    • Eidem S, Tete SM, Jul-Larsen A et al. Persistence and avidity maturation of antibodies to A(H1N1)pdm09 in healthcare workers following repeated annual vaccinations. Vaccine 33(33), 4146-4154 (2015).
    • (2015) Vaccine , vol.33 , Issue.33 , pp. 4146-4154
    • Eidem, S.1    Tete, S.M.2    Jul-Larsen, A.3
  • 62
    • 84940659978 scopus 로고    scopus 로고
    • H5N1 influenza virulence, pathogenicity and transmissibility: What do we know?
    • Neumann G. H5N1 influenza virulence, pathogenicity and transmissibility: what do we know? Future Virol. 10(8), 971-980 (2015).
    • (2015) Future Virol. , vol.10 , Issue.8 , pp. 971-980
    • Neumann, G.1
  • 63
    • 34047228863 scopus 로고    scopus 로고
    • H5N1 viruses and vaccines
    • Subbarao K, Luke C. H5N1 viruses and vaccines. PLoS Pathog. 3(3), e40 (2007).
    • (2007) PLoS Pathog. , vol.3 , Issue.3 , pp. e40
    • Subbarao, K.1    Luke, C.2
  • 64
    • 84901314963 scopus 로고    scopus 로고
    • Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge
    • Mann AJ, Noulin N, Catchpole A et al. Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge. PLoS ONE 9(5), e93761 (2014).
    • (2014) PLoS ONE , vol.9 , Issue.5 , pp. e93761
    • Mann, A.J.1    Noulin, N.2    Catchpole, A.3
  • 65
    • 33746141255 scopus 로고    scopus 로고
    • Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge
    • Govorkova EA, Webby RJ, Humberd J, Seiler JP, Webster RG. Immunization with reverse-genetics-produced H5N1 influenza vaccine protects ferrets against homologous and heterologous challenge. J. Infect. Dis. 194, 159-167 (2006).
    • (2006) J. Infect. Dis. , vol.194 , pp. 159-167
    • Govorkova, E.A.1    Webby, R.J.2    Humberd, J.3    Seiler, J.P.4    Webster, R.G.5
  • 66
    • 38849209040 scopus 로고    scopus 로고
    • Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine
    • Baras B, Stittelaar KJ, Simon JH et al. Cross-protection against lethal H5N1 challenge in ferrets with an adjuvanted pandemic influenza vaccine. PLoS ONE 3, e1401 (2008).
    • (2008) PLoS ONE , vol.3 , pp. e1401
    • Baras, B.1    Stittelaar, K.J.2    Simon, J.H.3
  • 67
    • 67650901824 scopus 로고    scopus 로고
    • Evaluation of vaccines for H5N1 influenza virus in ferrets reveals the potential for protective single-shot immunization
    • Middleton D, Rockman S, Pearse M et al. Evaluation of vaccines for H5N1 influenza virus in ferrets reveals the potential for protective single-shot immunization. J. Virol. 83, 7770-7778 (2009).
    • (2009) J. Virol. , vol.83 , pp. 7770-7778
    • Middleton, D.1    Rockman, S.2    Pearse, M.3
  • 68
    • 33646162162 scopus 로고    scopus 로고
    • Interfering vaccine (defective interfering influenza A virus) protects ferrets from influenza, and allows them to develop solid immunity to reinfection
    • Mann A, Marriott AC, Balasingam S et al. Interfering vaccine (defective interfering influenza A virus) protects ferrets from influenza, and allows them to develop solid immunity to reinfection. Vaccine 24, 4290-4296 (2006).
    • (2006) Vaccine , vol.24 , pp. 4290-4296
    • Mann, A.1    Marriott, A.C.2    Balasingam, S.3
  • 71
    • 77954982419 scopus 로고    scopus 로고
    • A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets
    • Bodewes R, Kreijtz JH, van Amerongen G et al. A single immunization with CoVaccine HT-adjuvanted H5N1 influenza virus vaccine induces protective cellular and humoral immune responses in ferrets. J. Virol. 84, 7943-7952 (2010).
    • (2010) J. Virol. , vol.84 , pp. 7943-7952
    • Bodewes, R.1    Kreijtz, J.H.2    Van Amerongen, G.3
  • 72
    • 74349124127 scopus 로고    scopus 로고
    • Animal models for the preclinical evaluation of candidate influenza vaccines
    • Bodewes R, Rimmelzwaan GF, Osterhaus AD. Animal models for the preclinical evaluation of candidate influenza vaccines. Expert Rev. Vaccines 9, 59-72 (2010).
    • (2010) Expert Rev. Vaccines , vol.9 , pp. 59-72
    • Bodewes, R.1    Rimmelzwaan, G.F.2    Osterhaus, A.D.3
  • 73
    • 1342268100 scopus 로고    scopus 로고
    • Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland
    • Mutsch M, Zhou W, Rhodes P et al. Use of the inactivated intranasal influenza vaccine and the risk of Bell's palsy in Switzerland. N. Engl. J. Med. 350, 896-903 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 896-903
    • Mutsch, M.1    Zhou, W.2    Rhodes, P.3
  • 74
    • 84859054098 scopus 로고    scopus 로고
    • AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland
    • Nohynek H, Jokinen J, Partinen M et al. AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland. PLoS ONE 7, e33536 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e33536
    • Nohynek, H.1    Jokinen, J.2    Partinen, M.3
  • 75
    • 84902332892 scopus 로고    scopus 로고
    • Development of live attenuated influenza vaccines against pandemic influenza strains
    • Coelingh KL, Luke CJ, Jin H, Talaat KR. Development of live attenuated influenza vaccines against pandemic influenza strains. Expert Rev. Vaccines 13(7), 855-871 (2014).
    • (2014) Expert Rev. Vaccines , vol.13 , Issue.7 , pp. 855-871
    • Coelingh, K.L.1    Luke, C.J.2    Jin, H.3    Talaat, K.R.4
  • 76
    • 84879780087 scopus 로고    scopus 로고
    • The prospects and challenges of universal vaccines for influenza
    • Subbarao K, Matsuoka Y. The prospects and challenges of universal vaccines for influenza. Trends Microbiol. 21(7), 350-358 (2013).
    • (2013) Trends Microbiol. , vol.21 , Issue.7 , pp. 350-358
    • Subbarao, K.1    Matsuoka, Y.2
  • 77
    • 78649336570 scopus 로고    scopus 로고
    • Pre-pandemic and pandemic influenza vaccines
    • Rockman S, Brown L. Pre-pandemic and pandemic influenza vaccines. Hum. Vaccin. 6(10), 792-801 (2010).
    • (2010) Hum. Vaccin. , vol.6 , Issue.10 , pp. 792-801
    • Rockman, S.1    Brown, L.2
  • 78
    • 0035858117 scopus 로고    scopus 로고
    • Live attenuated vaccines against influenza: An historical review
    • Wareing MD, Tannock GA. Live attenuated vaccines against influenza: an historical review. Vaccine 19, 3320-3323 (2001).
    • (2001) Vaccine , vol.19 , pp. 3320-3323
    • Wareing, M.D.1    Tannock, G.A.2
  • 79
    • 0035987429 scopus 로고    scopus 로고
    • Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines
    • Murphy BR, Coelingh K. Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines. Viral Immunol. 15, 295-323 (2002).
    • (2002) Viral Immunol. , vol.15 , pp. 295-323
    • Murphy, B.R.1    Coelingh, K.2
  • 81
    • 37549045609 scopus 로고    scopus 로고
    • Flu myths: Dispelling the myths associated with live attenuated influenza vaccine
    • Tosh PK, Boyce TG, Poland GA. Flu myths: dispelling the myths associated with live attenuated influenza vaccine. Mayo Clin. Proc. 83(1), 77-84 (2008).
    • (2008) Mayo Clin. Proc. , vol.83 , Issue.1 , pp. 77-84
    • Tosh, P.K.1    Boyce, T.G.2    Poland, G.A.3
  • 82
    • 0035858122 scopus 로고    scopus 로고
    • Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains
    • Tree JA, Richardson C, Fooks AR, Clegg JC, Looby D. Comparison of large-scale mammalian cell culture systems with egg culture for the production of influenza virus A vaccine strains. Vaccine 19(25-26), 3444-3450 (2001).
    • (2001) Vaccine , vol.19 , Issue.25-26 , pp. 3444-3450
    • Tree, J.A.1    Richardson, C.2    Fooks, A.R.3    Clegg, J.C.4    Looby, D.5
  • 83
    • 67449102487 scopus 로고    scopus 로고
    • Trivalent MDCK cell culture-derived influenza vaccine Optaflu (Novartis Vaccines)
    • Doroshenko A, Halperin SA. Trivalent MDCK cell culture-derived influenza vaccine Optaflu (Novartis Vaccines). Expert Rev. Vaccines 8(6), 679-688 (2009).
    • (2009) Expert Rev. Vaccines , vol.8 , Issue.6 , pp. 679-688
    • Doroshenko, A.1    Halperin, S.A.2
  • 84
    • 84865414271 scopus 로고    scopus 로고
    • Preflucel(R): A Vero-cell culture-derived trivalent influenza vaccine
    • Chan CY, Tambyah PA. Preflucel(R): A Vero-cell culture-derived trivalent influenza vaccine. Expert Rev. Vaccines 11(7), 759-773 (2012).
    • (2012) Expert Rev. Vaccines , vol.11 , Issue.7 , pp. 759-773
    • Chan, C.Y.1    Tambyah, P.A.2
  • 85
    • 84862814417 scopus 로고    scopus 로고
    • A cell-based backup to speed up pandemic influenza vaccine production
    • Lee MS, Hu AY. A cell-based backup to speed up pandemic influenza vaccine production. Trends Microbiol. 20(3), 103-105 (2012).
    • (2012) Trends Microbiol. , vol.20 , Issue.3 , pp. 103-105
    • Lee, M.S.1    Hu, A.Y.2
  • 86
    • 84864226154 scopus 로고    scopus 로고
    • A/H5N1 prepandemic influenza vaccine (whole virion, Vero cell-derived, inactivated) (Vepacel®)
    • Plosker GL. A/H5N1 prepandemic influenza vaccine (whole virion, Vero cell-derived, inactivated) (Vepacel®). Drugs 72(11), 1543-1557 (2012).
    • (2012) Drugs , vol.72 , Issue.11 , pp. 1543-1557
    • Plosker, G.L.1
  • 87
    • 71549137759 scopus 로고    scopus 로고
    • Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses
    • Li IW, Chan KH, To KW et al. Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses. J. Clin. Virol. 46(4), 325-330 (2009).
    • (2009) J. Clin. Virol. , vol.46 , Issue.4 , pp. 325-330
    • Li, I.W.1    Chan, K.H.2    To, K.W.3
  • 88
    • 43049120930 scopus 로고    scopus 로고
    • Development of stable influenza vaccine powder formulations: Challenges and possibilities
    • Amorij JP, Huckriede A, Wilschut J, Frijlink HW, Hinrichs WL. Development of stable influenza vaccine powder formulations: challenges and possibilities. Pharm. Res. 25(6), 1256-1273 (2008).
    • (2008) Pharm. Res. , vol.25 , Issue.6 , pp. 1256-1273
    • Amorij, J.P.1    Huckriede, A.2    Wilschut, J.3    Frijlink, H.W.4    Hinrichs, W.L.5
  • 89
    • 8444250949 scopus 로고    scopus 로고
    • Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material
    • Luykx DM, Casteleijn MG, Jiskoot W, Westdijk J, Jongen PM. Physicochemical studies on the stability of influenza haemagglutinin in vaccine bulk material. Eur. J. Pharm. Sci. 23, 65-75 (2004).
    • (2004) Eur. J. Pharm. Sci. , vol.23 , pp. 65-75
    • Luykx, D.M.1    Casteleijn, M.G.2    Jiskoot, W.3    Westdijk, J.4    Jongen, P.M.5
  • 90
    • 29244437487 scopus 로고    scopus 로고
    • Stability of influenza sub-unit vaccine. Does a couple of days outside the refrigerator matter?
    • Coenen F, Tolboom JT, Frijlink HW. Stability of influenza sub-unit vaccine. Does a couple of days outside the refrigerator matter? Vaccine 24, 525-531 (2006).
    • (2006) Vaccine , vol.24 , pp. 525-531
    • Coenen, F.1    Tolboom, J.T.2    Frijlink, H.W.3
  • 91
    • 34547603658 scopus 로고    scopus 로고
    • Rational design of an influenza subunit vaccine powder with sugar glass technology: Preventing conformational changes of haemagglutinin during freezing and freeze-drying
    • Amorij JP, Meulenaar J, Hinrichs WL et al. Rational design of an influenza subunit vaccine powder with sugar glass technology: preventing conformational changes of haemagglutinin during freezing and freeze-drying. Vaccine 25, 6447-6457 (2007).
    • (2007) Vaccine , vol.25 , pp. 6447-6457
    • Amorij, J.P.1    Meulenaar, J.2    Hinrichs, W.L.3
  • 93
    • 84948073656 scopus 로고    scopus 로고
    • Considerations of strategies to provide influenza vaccine year round
    • Lambach P, Alvarez AM, Hirve S et al. Considerations of strategies to provide influenza vaccine year round. Vaccine 33(47), 6493-6498 (2015).
    • (2015) Vaccine , vol.33 , Issue.47 , pp. 6493-6498
    • Lambach, P.1    Alvarez, A.M.2    Hirve, S.3
  • 94
    • 43049120930 scopus 로고    scopus 로고
    • Development of stable influenza vaccine powder formulations: Challenges and possibilities
    • Amorij JP, Huckriede A, Wilschut J, Frijlink HW, Hinrichs WL. Development of stable influenza vaccine powder formulations: challenges and possibilities. Pharm. Res. 25(6), 1256-1273 (2008).
    • (2008) Pharm. Res. , vol.25 , Issue.6 , pp. 1256-1273
    • Amorij, J.P.1    Huckriede, A.2    Wilschut, J.3    Frijlink, H.W.4    Hinrichs, W.L.5
  • 96
    • 84908376119 scopus 로고    scopus 로고
    • Epitope-based approaches to a universal influenza vaccine
    • Gottlieb T, Ben-Yedidia T. Epitope-based approaches to a universal influenza vaccine. J. Autoimmun. 54, 15-20 (2014).
    • (2014) J. Autoimmun. , vol.54 , pp. 15-20
    • Gottlieb, T.1    Ben-Yedidia, T.2
  • 97
    • 0032977751 scopus 로고    scopus 로고
    • Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus
    • Hsu SC, Chargelegue D, Obeid OE, Steward MW. Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus. J. Gen. Virol. 80(Pt 6), 1401-1405 (1999).
    • (1999) J. Gen. Virol. , vol.80 , pp. 1401-1405
    • Hsu, S.C.1    Chargelegue, D.2    Obeid, O.E.3    Steward, M.W.4
  • 98
    • 2942652411 scopus 로고    scopus 로고
    • Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses
    • Snyder JT, Belyakov IM, Dzutsev A, Lemonnier F, Berzofsky JA. Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses. J. Virol. 78(13), 7052-7060 (2004).
    • (2004) J. Virol. , vol.78 , Issue.13 , pp. 7052-7060
    • Snyder, J.T.1    Belyakov, I.M.2    Dzutsev, A.3    Lemonnier, F.4    Berzofsky, J.A.5
  • 99
    • 37349026910 scopus 로고    scopus 로고
    • Viral peptide immunogens: Current challenges and opportunities
    • Azizi A, Diaz-Mitoma F. Viral peptide immunogens: current challenges and opportunities. J. Pept. Sci. 13(12), 776-786 (2007).
    • (2007) J. Pept. Sci. , vol.13 , Issue.12 , pp. 776-786
    • Azizi, A.1    Diaz-Mitoma, F.2
  • 100
    • 0032708913 scopus 로고    scopus 로고
    • HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients
    • Pinto LA, Berzofsky JA, Fowke KR et al. HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients. AIDS 13(15), 2003-2012 (1999).
    • (1999) AIDS , vol.13 , Issue.15 , pp. 2003-2012
    • Pinto, L.A.1    Berzofsky, J.A.2    Fowke, K.R.3
  • 101
    • 0033787408 scopus 로고    scopus 로고
    • Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes
    • Nardin EH, Oliveira GA, Calvo-Calle JM et al. Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes. J. Infect. Dis. 182(5), 1486-1496 (2000).
    • (2000) J. Infect. Dis. , vol.182 , Issue.5 , pp. 1486-1496
    • Nardin, E.H.1    Oliveira, G.A.2    Calvo-Calle, J.M.3
  • 102
    • 0035657435 scopus 로고    scopus 로고
    • Peptide vaccines against hepatitis B virus: From animal model to human studies
    • Engler OB, Dai WJ, Sette A et al. Peptide vaccines against hepatitis B virus: from animal model to human studies. Mol. Immunol. 38(6), 457-465 (2001).
    • (2001) Mol. Immunol. , vol.38 , Issue.6 , pp. 457-465
    • Engler, O.B.1    Dai, W.J.2    Sette, A.3
  • 103
    • 0037157260 scopus 로고    scopus 로고
    • Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21
    • Kashala O, Amador R, Valero MV et al. Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21. Vaccine 20(17-18), 2263-2277 (2002).
    • (2002) Vaccine , vol.20 , Issue.17-18 , pp. 2263-2277
    • Kashala, O.1    Amador, R.2    Valero, M.V.3
  • 104
    • 33745969130 scopus 로고    scopus 로고
    • New CD4+ and CD8+ T cell responses induced in chronically HIV type-1-infected patients after immunizations with an HIV type 1 lipopeptide vaccine
    • Gahery H, Daniel N, Charmeteau B et al. New CD4+ and CD8+ T cell responses induced in chronically HIV type-1-infected patients after immunizations with an HIV type 1 lipopeptide vaccine. AIDS Res. Hum. Retroviruses 22(7), 684-694 (2006).
    • (2006) AIDS Res. Hum. Retroviruses , vol.22 , Issue.7 , pp. 684-694
    • Gahery, H.1    Daniel, N.2    Charmeteau, B.3
  • 105
    • 44849109375 scopus 로고    scopus 로고
    • Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
    • Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, van der Burg SH, Offringa R. Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation. Eur. J. Immunol. 38(4), 1033-1042 (2008).
    • (2008) Eur. J. Immunol. , vol.38 , Issue.4 , pp. 1033-1042
    • Bijker, M.S.1    Van Den Eeden, S.J.2    Franken, K.L.3    Melief, C.J.4    Van Der Burg, S.H.5    Offringa, R.6
  • 106
    • 38449106129 scopus 로고    scopus 로고
    • CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity
    • Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, Offringa R, van der Burg SH. CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity. J. Immunol. 179(8), 5033-5040 (2007).
    • (2007) J. Immunol. , vol.179 , Issue.8 , pp. 5033-5040
    • Bijker, M.S.1    Van Den Eeden, S.J.2    Franken, K.L.3    Melief, C.J.4    Offringa, R.5    Van Der Burg, S.H.6
  • 107
    • 34247849183 scopus 로고    scopus 로고
    • Effector and memory CTL differentiation
    • Williams MA, Bevan MJ. Effector and memory CTL differentiation. Annu. Rev. Immunol. 25, 171-192 (2007).
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 171-192
    • Williams, M.A.1    Bevan, M.J.2
  • 108
    • 79955649866 scopus 로고    scopus 로고
    • Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells
    • Taneichi M, Tanaka Y, Kakiuchi T, Uchida T. Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells. PLoS ONE 5(11), e15091 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.11 , pp. e15091
    • Taneichi, M.1    Tanaka, Y.2    Kakiuchi, T.3    Uchida, T.4
  • 109
    • 78649953803 scopus 로고    scopus 로고
    • Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes
    • Wang TT, Tan GS, Hai R et al. Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes. Proc. Natl Acad. Sci. USA 107(44), 18979-18984 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.44 , pp. 18979-18984
    • Wang, T.T.1    Tan, G.S.2    Hai, R.3
  • 110
    • 0037135673 scopus 로고    scopus 로고
    • Intranasal administration of a synthetic peptide vaccine encapsulated in liposome together with an anti-CD40 antibody induces protective immunity against influenza A virus in mice
    • Ninomiya A, Ogasawara K, Kajino K, Takada A, Kida H. Intranasal administration of a synthetic peptide vaccine encapsulated in liposome together with an anti-CD40 antibody induces protective immunity against influenza A virus in mice. Vaccine 20(25-26), 3123-3129 (2002).
    • (2002) Vaccine , vol.20 , Issue.25-26 , pp. 3123-3129
    • Ninomiya, A.1    Ogasawara, K.2    Kajino, K.3    Takada, A.4    Kida, H.5
  • 111
    • 73949118947 scopus 로고    scopus 로고
    • A CTL-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in HLA-A∗0201 transgenic mice
    • Matsui M, Kohyama S, Suda T et al. A CTL-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in HLA-A∗0201 transgenic mice. Biochem. Biophys. Res. Commun. 391(3), 1494-1499 (2010).
    • (2010) Biochem. Biophys. Res. Commun. , vol.391 , Issue.3 , pp. 1494-1499
    • Matsui, M.1    Kohyama, S.2    Suda, T.3
  • 112
    • 79955649866 scopus 로고    scopus 로고
    • Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells
    • Taneichi M, Tanaka Y, Kakiuchi T, Uchida T. Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells. PLoS ONE 5(11), e15091 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.11 , pp. e15091
    • Taneichi, M.1    Tanaka, Y.2    Kakiuchi, T.3    Uchida, T.4
  • 113
    • 80052891501 scopus 로고    scopus 로고
    • Cross-protective peptide vaccine against influenza A viruses developed in HLA-A∗2402 human immunity model
    • Ichihashi T, Yoshida R, Sugimoto C, Takada A, Kajino K. Cross-protective peptide vaccine against influenza A viruses developed in HLA-A∗2402 human immunity model. PLoS ONE 6(9), e24626 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.9 , pp. e24626
    • Ichihashi, T.1    Yoshida, R.2    Sugimoto, C.3    Takada, A.4    Kajino, K.5
  • 114
    • 84875311358 scopus 로고    scopus 로고
    • Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses
    • Ichihashi T, Satoh T, Sugimoto C, Kajino K. Emulsified phosphatidylserine, simple and effective peptide carrier for induction of potent epitope-specific T cell responses. PLoS ONE 8(3), e60068 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.3 , pp. e60068
    • Ichihashi, T.1    Satoh, T.2    Sugimoto, C.3    Kajino, K.4
  • 115
    • 84922432043 scopus 로고    scopus 로고
    • A novel peptide-based pan-influenza A vaccine: A double blind, randomised clinical trial of immunogenicity and safety
    • Francis JN, Bunce CJ, Horlock C et al. A novel peptide-based pan-influenza A vaccine: A double blind, randomised clinical trial of immunogenicity and safety. Vaccine 33(2), 396-402 (2014).
    • (2014) Vaccine , vol.33 , Issue.2 , pp. 396-402
    • Francis, J.N.1    Bunce, C.J.2    Horlock, C.3
  • 116
    • 0033959835 scopus 로고    scopus 로고
    • Induction of cytotoxic T lymphocyte activity by fusion-active peptide-containing virosomes
    • Arkema A, Huckriede A, Schoen P, Wilschut J, Daemen T. Induction of cytotoxic T lymphocyte activity by fusion-active peptide-containing virosomes. Vaccine 18(14), 1327-1333 (2000).
    • (2000) Vaccine , vol.18 , Issue.14 , pp. 1327-1333
    • Arkema, A.1    Huckriede, A.2    Schoen, P.3    Wilschut, J.4    Daemen, T.5
  • 117
    • 84908080093 scopus 로고    scopus 로고
    • Priming by a novel universal influenza vaccine (Multimeric-001)-A gateway for improving immune response in the elderly population
    • Atsmon J, Caraco Y, Ziv-Sefer S et al. Priming by a novel universal influenza vaccine (Multimeric-001)-A gateway for improving immune response in the elderly population. Vaccine 32(44), 5816-5823 (2014).
    • (2014) Vaccine , vol.32 , Issue.44 , pp. 5816-5823
    • Atsmon, J.1    Caraco, Y.2    Ziv-Sefer, S.3
  • 118
    • 84862678279 scopus 로고    scopus 로고
    • Towards tailored vaccine delivery: Needs, challenges and perspectives
    • Amorij JP, Kersten GF, Saluja V et al. Towards tailored vaccine delivery: needs, challenges and perspectives. J. Control. Release 161(2), 363-376 (2012).
    • (2012) J. Control. Release , vol.161 , Issue.2 , pp. 363-376
    • Amorij, J.P.1    Kersten, G.F.2    Saluja, V.3
  • 119
    • 84955292261 scopus 로고    scopus 로고
    • Engineering of the PapMV vaccine platform with a shortened M2e peptide leads to an effective one dose influenza vaccine
    • Carignan D, Thérien A, Rioux G et al. Engineering of the PapMV vaccine platform with a shortened M2e peptide leads to an effective one dose influenza vaccine. Vaccine 33(51), 7245-7253 (2015).
    • (2015) Vaccine , vol.33 , Issue.51 , pp. 7245-7253
    • Carignan, D.1    Thérien, A.2    Rioux, G.3
  • 120
  • 121
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of the M2 protein
    • Neirynck S, Deroo T, Saelens X, Vanlandschoot P, Jou WM, Fiers W. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat. Med. 5(10), 1157-1163 (1999).
    • (1999) Nat. Med. , vol.5 , Issue.10 , pp. 1157-1163
    • Neirynck, S.1    Deroo, T.2    Saelens, X.3    Vanlandschoot, P.4    Jou, W.M.5    Fiers, W.6
  • 122
    • 84884555137 scopus 로고    scopus 로고
    • Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection
    • Kim MC, Lee JS, Kwon YM et al. Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection. Antiviral. Res. 99(3), 328-335 (2013).
    • (2013) Antiviral. Res. , vol.99 , Issue.3 , pp. 328-335
    • Kim, M.C.1    Lee, J.S.2    Kwon, Y.M.3
  • 123
    • 82355170321 scopus 로고    scopus 로고
    • Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza
    • Shim BS, Choi YK, Yun CH et al. Sublingual immunization with M2-based vaccine induces broad protective immunity against influenza. PLoS ONE 6(11), e27953 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.11 , pp. e27953
    • Shim, B.S.1    Choi, Y.K.2    Yun, C.H.3
  • 124
    • 84908073773 scopus 로고    scopus 로고
    • Influenza M2 virus-like particles confer a broader range of cross protection to the strain-specific pre-existing immunity
    • Kim MC, Lee YN, Hwang HS et al. Influenza M2 virus-like particles confer a broader range of cross protection to the strain-specific pre-existing immunity. Vaccine 32(44), 5824-5831 (2014).
    • (2014) Vaccine , vol.32 , Issue.44 , pp. 5824-5831
    • Kim, M.C.1    Lee, Y.N.2    Hwang, H.S.3
  • 125
    • 84958781249 scopus 로고    scopus 로고
    • Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice
    • Rappazzo CG, Watkins HC, Guarino CM et al. Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice. Vaccine 34(10), 1252-1258 (2016).
    • (2016) Vaccine , vol.34 , Issue.10 , pp. 1252-1258
    • Rappazzo, C.G.1    Watkins, H.C.2    Guarino, C.M.3
  • 126
    • 84966702213 scopus 로고    scopus 로고
    • Mechanisms of cross-protection by influenza virus M2-based vaccines
    • Lee YN, Kim MC, Lee YT, Kim YJ, Kang SM. Mechanisms of cross-protection by influenza virus M2-based vaccines. Immune Netw. 15(5), 213-221 (2015).
    • (2015) Immune Netw. , vol.15 , Issue.5 , pp. 213-221
    • Lee, Y.N.1    Kim, M.C.2    Lee, Y.T.3    Kim, Y.J.4    Kang, S.M.5
  • 127
    • 84874277923 scopus 로고    scopus 로고
    • Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: A randomised, double-blind, placebo-controlled, Phase 1 study
    • Gurwith M, Lock M, Taylor EM et al. Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: A randomised, double-blind, placebo-controlled, Phase 1 study. Lancet Infect. Dis. 13(3), 238-250 (2013).
    • (2013) Lancet Infect. Dis. , vol.13 , Issue.3 , pp. 238-250
    • Gurwith, M.1    Lock, M.2    Taylor, E.M.3
  • 128
    • 84895508255 scopus 로고    scopus 로고
    • Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved influenza A antigens
    • Antrobus RD, Coughlan L, Berthoud TK et al. Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved influenza A antigens. Mol. Ther. 22(3), 668-674 (2014).
    • (2014) Mol. Ther. , vol.22 , Issue.3 , pp. 668-674
    • Antrobus, R.D.1    Coughlan, L.2    Berthoud, T.K.3
  • 130
    • 0034465117 scopus 로고    scopus 로고
    • Improving vaccine performance with adjuvants
    • Vogel FR. Improving vaccine performance with adjuvants. Clin Infect Dis. 3(Suppl. 3), S266-S270 (2000).
    • (2000) Clin Infect Dis. , vol.3 , pp. S266-S270
    • Vogel, F.R.1
  • 135
    • 0034623979 scopus 로고    scopus 로고
    • A randomized, double blind study in young healthy adults comparing cell mediated and humoral immune responses induced by influenza ISCOM vaccines and conventional vaccines
    • Rimmelzwaan GF, Nieuwkoop N, Brandenburg A et al. A randomized, double blind study in young healthy adults comparing cell mediated and humoral immune responses induced by influenza ISCOM vaccines and conventional vaccines. Vaccine 19(9-10), 1180-1187 (2000).
    • (2000) Vaccine , vol.19 , Issue.9-10 , pp. 1180-1187
    • Rimmelzwaan, G.F.1    Nieuwkoop, N.2    Brandenburg, A.3
  • 136
    • 80053645706 scopus 로고    scopus 로고
    • Evaluation of a virosomal H5N1 vaccine formulated with Matrix M adjuvant in a Phase i clinical trial
    • Cox RJ, Pedersen G, Madhun AS et al. Evaluation of a virosomal H5N1 vaccine formulated with Matrix M adjuvant in a Phase I clinical trial. Vaccine 29(45), 8049-8059 (2011).
    • (2011) Vaccine , vol.29 , Issue.45 , pp. 8049-8059
    • Cox, R.J.1    Pedersen, G.2    Madhun, A.S.3
  • 138
    • 79951922551 scopus 로고    scopus 로고
    • PCPP-formulated H5N1 influenza vaccine displays improved stability and dose-sparing effect in lethal challenge studies
    • Andrianov AK, Decollibus DP, Marin A, Webb A, Griffin Y, Webby RJ. PCPP-formulated H5N1 influenza vaccine displays improved stability and dose-sparing effect in lethal challenge studies. J. Pharm. Sci. 100(4), 1436-1443 (2011).
    • (2011) J. Pharm. Sci. , vol.100 , Issue.4 , pp. 1436-1443
    • Andrianov, A.K.1    Decollibus, D.P.2    Marin, A.3    Webb, A.4    Griffin, Y.5    Webby, R.J.6
  • 139
    • 84864008199 scopus 로고    scopus 로고
    • Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax polysaccharide adjuvant
    • Gordon DL, Sajkov D, Woodman RJ et al. Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax polysaccharide adjuvant. Vaccine 30(36), 5407-5416 (2012).
    • (2012) Vaccine , vol.30 , Issue.36 , pp. 5407-5416
    • Gordon, D.L.1    Sajkov, D.2    Woodman, R.J.3
  • 140
    • 84864000393 scopus 로고    scopus 로고
    • Advax, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses
    • Honda-Okubo Y, Saade F, Petrovsky N. Advax, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses. Vaccine 30(36), 5373-5381 (2012).
    • (2012) Vaccine , vol.30 , Issue.36 , pp. 5373-5381
    • Honda-Okubo, Y.1    Saade, F.2    Petrovsky, N.3
  • 141
    • 84904332164 scopus 로고    scopus 로고
    • Intranasal chitosan-DNA vaccines that protect across influenza virus subtypes
    • Sawaengsak C, Mori Y, Yamanishi K et al. Intranasal chitosan-DNA vaccines that protect across influenza virus subtypes. Int. J. Pharm. 473(1-2), 113-125 (2014).
    • (2014) Int. J. Pharm. , vol.473 , Issue.1-2 , pp. 113-125
    • Sawaengsak, C.1    Mori, Y.2    Yamanishi, K.3
  • 142
    • 84906089277 scopus 로고    scopus 로고
    • Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity
    • Pérez-Girón JV, Belicha-Villanueva A, Hassan E et al. Mucosal polyinosinic-polycytidylic acid improves protection elicited by replicating influenza vaccines via enhanced dendritic cell function and T cell immunity. J. Immunol. 193(3), 1324-1332 (2014).
    • (2014) J. Immunol. , vol.193 , Issue.3 , pp. 1324-1332
    • Pérez-Girón, J.V.1    Belicha-Villanueva, A.2    Hassan, E.3
  • 143
    • 3843052308 scopus 로고    scopus 로고
    • Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine
    • Cooper CL, Davis HL, Morris ML et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine 22, 3136-3143 (2004).
    • (2004) Vaccine , vol.22 , pp. 3136-3143
    • Cooper, C.L.1    Davis, H.L.2    Morris, M.L.3
  • 144
    • 0033526828 scopus 로고    scopus 로고
    • Augmentation of human influenza A virus-specific cytotoxic T lymphocyte memory by influenza vaccine and adjuvanted carriers (ISCOMS)
    • Ennis FA, Cruz J, Jameson J, Klein M, Burt D, Thipphawong J. Augmentation of human influenza A virus-specific cytotoxic T lymphocyte memory by influenza vaccine and adjuvanted carriers (ISCOMS). Virology 259(2), 256-261 (1999).
    • (1999) Virology , vol.259 , Issue.2 , pp. 256-261
    • Ennis, F.A.1    Cruz, J.2    Jameson, J.3    Klein, M.4    Burt, D.5    Thipphawong, J.6
  • 145
    • 34047189362 scopus 로고    scopus 로고
    • Humoral and cell-mediated immune responses of humans to inactivated influenza vaccine with or without QS21 adjuvant
    • Mbawuike I, Zang Y, Couch RB. Humoral and cell-mediated immune responses of humans to inactivated influenza vaccine with or without QS21 adjuvant. Vaccine 25(17), 3263-3269 (2007).
    • (2007) Vaccine , vol.25 , Issue.17 , pp. 3263-3269
    • Mbawuike, I.1    Zang, Y.2    Couch, R.B.3
  • 146
    • 80052508960 scopus 로고    scopus 로고
    • Meta-analysis of the immunogenicity and tolerability of pandemic influenza A 2009 (H1N1) vaccines
    • Manzoli L, De Vito C, Salanti G, D'Addario M, Villari P, Ioannidis JP. Meta-analysis of the immunogenicity and tolerability of pandemic influenza A 2009 (H1N1) vaccines. PLoS ONE 6(9), e24384 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.9 , pp. e24384
    • Manzoli, L.1    De Vito, C.2    Salanti, G.3    D'Addario, M.4    Villari, P.5    Ioannidis, J.P.6
  • 147
    • 78649759121 scopus 로고    scopus 로고
    • Intranasal immunization with influenza VLPs incorporating membrane-anchored flagellin induces strong heterosubtypic protection
    • Wang B-Z, Xu R, Quan F-S, Kang S-M, Wang L, Compans RW. Intranasal immunization with influenza VLPs incorporating membrane-anchored flagellin induces strong heterosubtypic protection. PLoS ONE 5(11), e13972 (2010).
    • (2010) PLoS ONE , vol.5 , Issue.11 , pp. e13972
    • Wang, B.-Z.1    Xu, R.2    Quan, F.-S.3    Kang, S.-M.4    Wang, L.5    Compans, R.W.6
  • 148
    • 78649741148 scopus 로고    scopus 로고
    • Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults
    • Treanor JJ, Taylor DN, Tussey L et al. Safety and immunogenicity of a recombinant hemagglutinin influenza-flagellin fusion vaccine (VAX125) in healthy young adults. Vaccine 28(52), 8268-8274 (2010).
    • (2010) Vaccine , vol.28 , Issue.52 , pp. 8268-8274
    • Treanor, J.J.1    Taylor, D.N.2    Tussey, L.3
  • 149
    • 84864945063 scopus 로고    scopus 로고
    • Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response
    • Taylor DN, Treanor JJ, Sheldon EA et al. Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response. Vaccine 30(39), 5761-5769 (2012).
    • (2012) Vaccine , vol.30 , Issue.39 , pp. 5761-5769
    • Taylor, D.N.1    Treanor, J.J.2    Sheldon, E.A.3
  • 150
    • 84878527308 scopus 로고    scopus 로고
    • Replication and immunogenicity of swine, equine, and avian h3 subtype influenza viruses in mice and ferrets
    • Baz M, Paskel M, Matsuoka Y et al. Replication and immunogenicity of swine, equine, and avian h3 subtype influenza viruses in mice and ferrets. J. Virol. 87, 6901-6910 (2013).
    • (2013) J. Virol. , vol.87 , pp. 6901-6910
    • Baz, M.1    Paskel, M.2    Matsuoka, Y.3
  • 151
    • 0025775165 scopus 로고
    • Passive transfer of local immunity to influenza virus by IgA antibody
    • Renegar KB, Small PAJ. Passive transfer of local immunity to influenza virus by IgA antibody. J. Immunol. 146, 1972-1978 (1991).
    • (1991) J. Immunol. , vol.146 , pp. 1972-1978
    • Renegar, K.B.1    Small, P.A.J.2
  • 152
    • 0033913482 scopus 로고    scopus 로고
    • Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine
    • Belshe RB, Gruber WC, Mendelman PM et al. Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. J. Pediatr. 136, 168-175 (2000).
    • (2000) J. Pediatr. , vol.136 , pp. 168-175
    • Belshe, R.B.1    Gruber, W.C.2    Mendelman, P.M.3
  • 153
    • 3142682239 scopus 로고    scopus 로고
    • Mapping the antigenic and genetic evolution of influenza virus
    • Smith DR, Lapedes AS, de Jong JC et al. Mapping the antigenic and genetic evolution of influenza virus. Science 305(5682), 371-376 (2004).
    • (2004) Science , vol.305 , Issue.5682 , pp. 371-376
    • Smith, D.R.1    Lapedes, A.S.2    De Jong, J.C.3
  • 154
    • 84880626687 scopus 로고    scopus 로고
    • Integrative genomic analysis of the human immune response to influenza vaccination
    • Franco LM, Bucasas KL, Wells JM et al. Integrative genomic analysis of the human immune response to influenza vaccination. Elife 2, e00299 (2013).
    • (2013) Elife , vol.2 , pp. e00299
    • Franco, L.M.1    Bucasas, K.L.2    Wells, J.M.3
  • 155
    • 70349967937 scopus 로고    scopus 로고
    • M2e-based universal influenza A vaccine
    • Fiers W, de Filette M, El Bakkouri K et al. M2e-based universal influenza A vaccine. Vaccine 27, 6280-6283 (2009).
    • (2009) Vaccine , vol.27 , pp. 6280-6283
    • Fiers, W.1    De Filette, M.2    El Bakkouri, K.3
  • 156
    • 84873023493 scopus 로고    scopus 로고
    • Toward a universal influenza virus vaccine: Prospects and challenges
    • Pica N, Palese P. Toward a universal influenza virus vaccine: prospects and challenges. Annu. Rev. Med. 64, 189-202 (2013).
    • (2013) Annu. Rev. Med. , vol.64 , pp. 189-202
    • Pica, N.1    Palese, P.2
  • 158
    • 47649085021 scopus 로고    scopus 로고
    • Correlation of cellular immune responses with protection against culture-confirmed influenza virus in young children
    • Forrest BD, Pride MW, Dunning AJ et al. Correlation of cellular immune responses with protection against culture-confirmed influenza virus in young children. Clin. Vaccine Immunol. 15, 1042-1053 (2008).
    • (2008) Clin. Vaccine Immunol. , vol.15 , pp. 1042-1053
    • Forrest, B.D.1    Pride, M.W.2    Dunning, A.J.3
  • 159
    • 84862776631 scopus 로고    scopus 로고
    • Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans
    • Wilkinson TM, Li CKF, Chui CSC et al. Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. Nat. Med. 18, 274-280 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 274-280
    • Wilkinson, T.M.1    Li, C.K.F.2    Chui, C.S.C.3
  • 160
    • 84887473368 scopus 로고    scopus 로고
    • Cellular immune correlates of protection against symptomatic pandemic influenza
    • Sridhar S, Begom S, Bermingham A et al. Cellular immune correlates of protection against symptomatic pandemic influenza. Nat. Med. 19, 1305-1312 (2013).
    • (2013) Nat. Med. , vol.19 , pp. 1305-1312
    • Sridhar, S.1    Begom, S.2    Bermingham, A.3


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