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Volumn 54, Issue , 2014, Pages 15-20

Epitope-based approaches to a universal influenza vaccine

Author keywords

Influenza; Multimeric 001; Pandemic; Peptide; Seasonal; Vaccines

Indexed keywords

EPITOPE; INFLUENZA VACCINE;

EID: 84908376119     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2014.07.005     Document Type: Article
Times cited : (50)

References (67)
  • 1
    • 85028100615 scopus 로고    scopus 로고
    • Arnold, N. Cox, Y. Kawaoka (Eds.)
    • Orthomyxoviruses: influenza 1998, Arnold. N. Cox, Y. Kawaoka (Eds.).
    • (1998) Orthomyxoviruses: influenza
  • 2
    • 0020050946 scopus 로고
    • Molecular mechanism of variation in influenza viruses
    • Webster R., Laver W., Air G., Schild G. Molecular mechanism of variation in influenza viruses. Nature 1982, 296(5853):115-121.
    • (1982) Nature , vol.296 , Issue.5853 , pp. 115-121
    • Webster, R.1    Laver, W.2    Air, G.3    Schild, G.4
  • 4
    • 84896019901 scopus 로고    scopus 로고
    • Eliciting broadly protective antibody responses against influenza
    • Kirchenbaum G.A., Ross T.M. Eliciting broadly protective antibody responses against influenza. Curr Opin Immunol 2014, 12(28C):71-76.
    • (2014) Curr Opin Immunol , vol.12 , Issue.28 C , pp. 71-76
    • Kirchenbaum, G.A.1    Ross, T.M.2
  • 5
    • 85028118855 scopus 로고    scopus 로고
    • http://www.cdc.gov/flu/about/qa/vaccineeffect.htm.
  • 6
    • 32044453088 scopus 로고    scopus 로고
    • Antibody response to influenza vaccination in the elderly: a quantitative review
    • Goodwin K., Viboud C., Simonsen L. Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine 2006, 24(8):1159-1169.
    • (2006) Vaccine , vol.24 , Issue.8 , pp. 1159-1169
    • Goodwin, K.1    Viboud, C.2    Simonsen, L.3
  • 7
    • 85028102374 scopus 로고    scopus 로고
    • http://www.cdc.gov/flu/about/qa/flushot.htm.
  • 8
    • 25844467829 scopus 로고    scopus 로고
    • Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review
    • Jefferson T., Rivetti D., Rivetti A., Rudin M., Di Pietrantonj C., Demicheli V. Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review. Lancet 2005, 366(9492):1165-1174.
    • (2005) Lancet , vol.366 , Issue.9492 , pp. 1165-1174
    • Jefferson, T.1    Rivetti, D.2    Rivetti, A.3    Rudin, M.4    Di Pietrantonj, C.5    Demicheli, V.6
  • 9
    • 85028114619 scopus 로고    scopus 로고
    • http://www.cidrap.umn.edu/cidrap/content/influenza/panflu/news/may2110vaxprod.html.
  • 10
    • 85028099281 scopus 로고    scopus 로고
    • http://www.cidrap.umn.edu/news-perspective/2012/11/fda-clears-first-cell-based-flu-vaccine.
  • 11
    • 7044263390 scopus 로고    scopus 로고
    • Vaccine adjuvants: current state and future trends
    • Petrovsky N., Aguilar J.C. Vaccine adjuvants: current state and future trends. Immunol Cell Biol 2004, 82:488-496.
    • (2004) Immunol Cell Biol , vol.82 , pp. 488-496
    • Petrovsky, N.1    Aguilar, J.C.2
  • 12
    • 85028122176 scopus 로고    scopus 로고
    • http://www.cdc.gov/vaccinesafety/Concerns/h1n1_narcolepsy_pandemrix.html.
  • 13
    • 70349771206 scopus 로고    scopus 로고
    • Potential for a global dynamic of influenza A (H1N1)
    • 12
    • Flahault A., Vergu E., Boëlle P.Y. Potential for a global dynamic of influenza A (H1N1). BMC Infect Dis 2009, 9:129. 12.
    • (2009) BMC Infect Dis , vol.9 , pp. 129
    • Flahault, A.1    Vergu, E.2    Boëlle, P.Y.3
  • 14
    • 85028092095 scopus 로고    scopus 로고
    • http://www.phe.gov/Preparedness/mcm/H1N1-retrospective/Documents/H1N1-retrospective.pdf.
  • 15
    • 85028113612 scopus 로고    scopus 로고
    • http://www.examiner.com/x-29691-Boulder-Healthy-Living-Examiner~y2010m1d4-H1N1-Swine-Flu-Vaccine-Update-European-countries-selling-excess-H1N1-swine-flu-vaccine.
  • 16
    • 85028108269 scopus 로고    scopus 로고
    • http://www.cdc.gov/flu/professionals/acip/2013-summary-recommendations.html.
  • 17
    • 52049100400 scopus 로고    scopus 로고
    • Stockpiling prepandemic influenza vaccines: a new cornerstone of pandemic preparedness plans
    • Jennings L.C., Monto A.S., Chan P.K., Szucs T.D., Nicholson K.G. Stockpiling prepandemic influenza vaccines: a new cornerstone of pandemic preparedness plans. Lancet 2008, 8:650-658.
    • (2008) Lancet , vol.8 , pp. 650-658
    • Jennings, L.C.1    Monto, A.S.2    Chan, P.K.3    Szucs, T.D.4    Nicholson, K.G.5
  • 19
    • 85028120137 scopus 로고    scopus 로고
    • The macroeconmic costs of a global influenza pandemic
    • In press,
    • Keogh-Brown M, McDonald S, Edmunds WJ, Beutels P, Smith RD. The macroeconmic costs of a global influenza pandemic. In press, https://www.gtap.agecon.purdue.edu/resources/download/3828.pdf.
    • Keogh-Brown, M.1    McDonald, S.2    Edmunds, W.J.3    Beutels, P.4    Smith, R.D.5
  • 20
    • 84870557383 scopus 로고    scopus 로고
    • The economic value of a quadrivalent versus trivalent influenza vaccine
    • Lee B.Y., Bartsch S.M., Willig A.M. The economic value of a quadrivalent versus trivalent influenza vaccine. Vaccine 2012, 30:7443-7446.
    • (2012) Vaccine , vol.30 , pp. 7443-7446
    • Lee, B.Y.1    Bartsch, S.M.2    Willig, A.M.3
  • 21
    • 0018950287 scopus 로고
    • Outcome of influenza infection: effect of site of initial infection and heterotypic immunity
    • Yetter R., Lehrer S., Ramphal R., Small Pj Outcome of influenza infection: effect of site of initial infection and heterotypic immunity. Infect Immun 1980, 29(2):654-662.
    • (1980) Infect Immun , vol.29 , Issue.2 , pp. 654-662
    • Yetter, R.1    Lehrer, S.2    Ramphal, R.3    Small, P.4
  • 22
    • 67650457114 scopus 로고    scopus 로고
    • Infection of mice with a human influenza A/H3N2 virus induces protective immunity against lethal infection with influenza A/H5N1 virus
    • Kreijtz J.H., Bodewes R., van den Brand J.M., de Mutsert G., Baas C., van Amerongen G., et al. Infection of mice with a human influenza A/H3N2 virus induces protective immunity against lethal infection with influenza A/H5N1 virus. Vaccine 2009, 27(36):4983-4989.
    • (2009) Vaccine , vol.27 , Issue.36 , pp. 4983-4989
    • Kreijtz, J.H.1    Bodewes, R.2    van den Brand, J.M.3    de Mutsert, G.4    Baas, C.5    van Amerongen, G.6
  • 23
    • 0031066918 scopus 로고    scopus 로고
    • Mechanisms of heterosubtypic immunity to lethal influenza a virus infection in fully immunocompetent, T cell-depleted, beta2-microglobulin-deficient, and J chain-deficient mice
    • Epstein S.L., Lo C.Y., Misplon J.A., Lawson C.M., Hendrickson B.A., Max E.E., et al. Mechanisms of heterosubtypic immunity to lethal influenza a virus infection in fully immunocompetent, T cell-depleted, beta2-microglobulin-deficient, and J chain-deficient mice. JImmunol 1997, 158(3):1222-1230.
    • (1997) JImmunol , vol.158 , Issue.3 , pp. 1222-1230
    • Epstein, S.L.1    Lo, C.Y.2    Misplon, J.A.3    Lawson, C.M.4    Hendrickson, B.A.5    Max, E.E.6
  • 24
    • 70449571952 scopus 로고    scopus 로고
    • Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication
    • Wunderlich K., Mayer D., Ranadheera C., Holler A.S., Mänz B., Martin A., et al. Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication. PLoS One 2009, 4(10):e7517.
    • (2009) PLoS One , vol.4 , Issue.10 , pp. e7517
    • Wunderlich, K.1    Mayer, D.2    Ranadheera, C.3    Holler, A.S.4    Mänz, B.5    Martin, A.6
  • 25
    • 77956415891 scopus 로고    scopus 로고
    • Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus
    • Skountzou I., Koutsonanos D.G., Kim J.H., Powers R., Satyabhama L., Masseoud F., et al. Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus. JImmunol 2010, 185(3):1642-1649.
    • (2010) JImmunol , vol.185 , Issue.3 , pp. 1642-1649
    • Skountzou, I.1    Koutsonanos, D.G.2    Kim, J.H.3    Powers, R.4    Satyabhama, L.5    Masseoud, F.6
  • 26
    • 77954476468 scopus 로고    scopus 로고
    • Cross-reactive neutralizing antibodies directed against pandemic H1N1 2009 virus are protective in a highly sensitive DBA/2 mouse influenza model
    • Boon A.C., deBeauchamp J., Krauss S., Rubrum A., Webb A.D., Webster R.G., et al. Cross-reactive neutralizing antibodies directed against pandemic H1N1 2009 virus are protective in a highly sensitive DBA/2 mouse influenza model. JVirol 2010, 84(15):7662-7667.
    • (2010) JVirol , vol.84 , Issue.15 , pp. 7662-7667
    • Boon, A.C.1    deBeauchamp, J.2    Krauss, S.3    Rubrum, A.4    Webb, A.D.5    Webster, R.G.6
  • 27
    • 77953295181 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus
    • Tu W., Mao H., Zheng J., Liu Y., Chiu S.S., Qin G., et al. Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus. JVirol 2010, 84(13):6527-6535.
    • (2010) JVirol , vol.84 , Issue.13 , pp. 6527-6535
    • Tu, W.1    Mao, H.2    Zheng, J.3    Liu, Y.4    Chiu, S.S.5    Qin, G.6
  • 28
    • 0037456637 scopus 로고    scopus 로고
    • N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication
    • Liu W., Li H., Chen Y. N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication. FEMS Immunol Med Microbiol 2003, 35:141-146.
    • (2003) FEMS Immunol Med Microbiol , vol.35 , pp. 141-146
    • Liu, W.1    Li, H.2    Chen, Y.3
  • 29
    • 61549132283 scopus 로고    scopus 로고
    • Auniversal epitope-based influenza vaccine and its efficacy against H5N1
    • Adar Y., Singer Y., Levi R., Tzehoval E., Perk S., Banet-Noach C., et al. Auniversal epitope-based influenza vaccine and its efficacy against H5N1. Vaccine 2009, 27(15):2099-2107.
    • (2009) Vaccine , vol.27 , Issue.15 , pp. 2099-2107
    • Adar, Y.1    Singer, Y.2    Levi, R.3    Tzehoval, E.4    Perk, S.5    Banet-Noach, C.6
  • 30
    • 77950831046 scopus 로고    scopus 로고
    • Cytotoxic T cells are the predominant players providing cross-protective immunity induced by {gamma}-irradiated influenza a viruses
    • Furuya Y., Chan J., Regner M., Lobigs M., Koskinen A., Kok T., et al. Cytotoxic T cells are the predominant players providing cross-protective immunity induced by {gamma}-irradiated influenza a viruses. JVirol 2010, 84(9):4212-4221.
    • (2010) JVirol , vol.84 , Issue.9 , pp. 4212-4221
    • Furuya, Y.1    Chan, J.2    Regner, M.3    Lobigs, M.4    Koskinen, A.5    Kok, T.6
  • 31
    • 0036772366 scopus 로고    scopus 로고
    • Aretro-inverso peptide analogue of influenza virus hemagglutinin B-cell epitope 91-108 induces a strong mucosal and systemic immune response and confers protection in mice after intranasal immunization
    • Ben-Yedidia T., Beignon A., Partidos C., Muller S., Arnon R. Aretro-inverso peptide analogue of influenza virus hemagglutinin B-cell epitope 91-108 induces a strong mucosal and systemic immune response and confers protection in mice after intranasal immunization. Mol Immunol 2002, 39(5-6):323-331.
    • (2002) Mol Immunol , vol.39 , Issue.5-6 , pp. 323-331
    • Ben-Yedidia, T.1    Beignon, A.2    Partidos, C.3    Muller, S.4    Arnon, R.5
  • 32
    • 0022504418 scopus 로고
    • Functional analysis of influenza-specific helper T cell clones invivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin
    • Scherle P., Gerhard W. Functional analysis of influenza-specific helper T cell clones invivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. JExp Med 1986, 164(4):1114-1128.
    • (1986) JExp Med , vol.164 , Issue.4 , pp. 1114-1128
    • Scherle, P.1    Gerhard, W.2
  • 33
    • 0019133770 scopus 로고
    • Cell cooperation in antibody responses to influenza virus. I. Priming of helper T cells by internal components of virion
    • Russell S., Liew F. Cell cooperation in antibody responses to influenza virus. I. Priming of helper T cells by internal components of virion. Eur J Immunol 1980, 10(10):791-796.
    • (1980) Eur J Immunol , vol.10 , Issue.10 , pp. 791-796
    • Russell, S.1    Liew, F.2
  • 34
    • 33750980717 scopus 로고    scopus 로고
    • Current status of short synthetic peptides as vaccines
    • Hans D., Young P., Fairlie D. Current status of short synthetic peptides as vaccines. Med Chem 2006, 2(6):627-646.
    • (2006) Med Chem , vol.2 , Issue.6 , pp. 627-646
    • Hans, D.1    Young, P.2    Fairlie, D.3
  • 36
    • 0030842457 scopus 로고    scopus 로고
    • Design of peptide and polypeptide vaccines
    • Ben-Yedidia T., Arnon R. Design of peptide and polypeptide vaccines. Curr Opin Biotechnol 1997, 8(4):442-448.
    • (1997) Curr Opin Biotechnol , vol.8 , Issue.4 , pp. 442-448
    • Ben-Yedidia, T.1    Arnon, R.2
  • 37
    • 2942652411 scopus 로고    scopus 로고
    • Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses
    • Snyder J., Belyakov I., Dzutsev A., Lemmonier F., Berzofsky J. Protection against lethal vaccinia virus challenge in HLA-A2 transgenic mice by immunization with a single CD8+ T-cell peptide epitope of vaccinia and variola viruses. JVirol 2004, 78:7052-7060.
    • (2004) JVirol , vol.78 , pp. 7052-7060
    • Snyder, J.1    Belyakov, I.2    Dzutsev, A.3    Lemmonier, F.4    Berzofsky, J.5
  • 38
    • 0032977751 scopus 로고    scopus 로고
    • Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus
    • Hsu S., Chargelegue D., Obeid O., Steward M. Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus. JGen Virol 1999, 80(Pt 6):1401-1405.
    • (1999) JGen Virol , vol.80 , pp. 1401-1405
    • Hsu, S.1    Chargelegue, D.2    Obeid, O.3    Steward, M.4
  • 39
    • 37349026910 scopus 로고    scopus 로고
    • Viral peptide immunogens: current challenges and opportunities
    • Azizi A., Diaz-Mitoma F. Viral peptide immunogens: current challenges and opportunities. JPept Sci 2007, 13(12):776-786.
    • (2007) JPept Sci , vol.13 , Issue.12 , pp. 776-786
    • Azizi, A.1    Diaz-Mitoma, F.2
  • 40
    • 0037157260 scopus 로고    scopus 로고
    • Safety, tolerability and immunogenicity of new formulations of the plasmodium falciparum malaria peptide vaccine spf66 combined with the immunological adjuvant QS-21
    • Kashala O., Amador R., Valero M.V., Moreno A., Barbosa A., Nickel B., et al. Safety, tolerability and immunogenicity of new formulations of the plasmodium falciparum malaria peptide vaccine spf66 combined with the immunological adjuvant QS-21. Vaccine 2002, 20(17-18):2263-2277.
    • (2002) Vaccine , vol.20 , Issue.17-18 , pp. 2263-2277
    • Kashala, O.1    Amador, R.2    Valero, M.V.3    Moreno, A.4    Barbosa, A.5    Nickel, B.6
  • 41
    • 0033787408 scopus 로고    scopus 로고
    • Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes
    • Nardin E.H., Oliveira G.A., Calvo-Calle J.M., Castro Z.R., Nussenzweig R.S., Schmeckpeper B., et al. Synthetic malaria peptide vaccine elicits high levels of antibodies in vaccinees of defined HLA genotypes. JInfect Dis 2000, 182(5):1486-1496.
    • (2000) JInfect Dis , vol.182 , Issue.5 , pp. 1486-1496
    • Nardin, E.H.1    Oliveira, G.A.2    Calvo-Calle, J.M.3    Castro, Z.R.4    Nussenzweig, R.S.5    Schmeckpeper, B.6
  • 42
    • 0035657435 scopus 로고    scopus 로고
    • Peptide vaccines against Hepatitis B virus: from animal model to human studies
    • Engler O.B., Dai W.J., Sette A., Hunziker I.P., Reichen J., Pichler W.J., et al. Peptide vaccines against Hepatitis B virus: from animal model to human studies. Mol Immunol 2001, 38(6):457-465.
    • (2001) Mol Immunol , vol.38 , Issue.6 , pp. 457-465
    • Engler, O.B.1    Dai, W.J.2    Sette, A.3    Hunziker, I.P.4    Reichen, J.5    Pichler, W.J.6
  • 43
    • 33745969130 scopus 로고    scopus 로고
    • New cd4+ and cd8+ T cell responses induced in chronically hiv type-1-infected patients after immunizations with an HIV type 1 lipopeptide vaccine
    • Gahery H., Daniel N., Charmeteau B., Ourth L., Jackson A., Andrieu M., et al. New cd4+ and cd8+ T cell responses induced in chronically hiv type-1-infected patients after immunizations with an HIV type 1 lipopeptide vaccine. AIDS Res Hum Retroviruses 2006, 22(7):684-694.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , Issue.7 , pp. 684-694
    • Gahery, H.1    Daniel, N.2    Charmeteau, B.3    Ourth, L.4    Jackson, A.5    Andrieu, M.6
  • 44
    • 0032708913 scopus 로고    scopus 로고
    • HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients
    • Pinto L.A., Berzofsky J.A., Fowke K.R., Little R.F., Merced-Galindez F., Humphrey R., et al. HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients. AIDS 1999, 13(15):2003-2012.
    • (1999) AIDS , vol.13 , Issue.15 , pp. 2003-2012
    • Pinto, L.A.1    Berzofsky, J.A.2    Fowke, K.R.3    Little, R.F.4    Merced-Galindez, F.5    Humphrey, R.6
  • 45
    • 60849088256 scopus 로고    scopus 로고
    • Neutralizing anti-influenza virus monoclonal antibodies: therapeutics and tools for discovery
    • Martinez O., Tsibane T., Basler C. Neutralizing anti-influenza virus monoclonal antibodies: therapeutics and tools for discovery. Int Rev Immunol 2009, 28(1):69-92.
    • (2009) Int Rev Immunol , vol.28 , Issue.1 , pp. 69-92
    • Martinez, O.1    Tsibane, T.2    Basler, C.3
  • 46
    • 62049083943 scopus 로고    scopus 로고
    • Structural and functional bases for broad-spectrum neutralization of avian and human influenza a viruses
    • Sui J., Hwang W.C., Perez S., Wei G., Aird D., Chen L.M., et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza a viruses. Nat Struct Mol Biol 2009, 16(3):265-273.
    • (2009) Nat Struct Mol Biol , vol.16 , Issue.3 , pp. 265-273
    • Sui, J.1    Hwang, W.C.2    Perez, S.3    Wei, G.4    Aird, D.5    Chen, L.M.6
  • 47
    • 77649242815 scopus 로고    scopus 로고
    • Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins
    • Wang T.T., Tan G.S., Hai R., Pica N., Petersen E., Moran T.M., et al. Broadly protective monoclonal antibodies against H3 influenza viruses following sequential immunization with different hemagglutinins. PLoS Pathog 2010, 6(2):e1000796.
    • (2010) PLoS Pathog , vol.6 , Issue.2 , pp. e1000796
    • Wang, T.T.1    Tan, G.S.2    Hai, R.3    Pica, N.4    Petersen, E.5    Moran, T.M.6
  • 48
    • 84883859603 scopus 로고    scopus 로고
    • Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease
    • Khurana S., Loving C.L., Manischewitz J., King L.R., Gauger P.C., Henningson J., et al. Vaccine-induced anti-HA2 antibodies promote virus fusion and enhance influenza virus respiratory disease. Sci Transl Med 2013, 5(200):200ra114. 28.
    • (2013) Sci Transl Med , vol.5 , Issue.200 , pp. 200
    • Khurana, S.1    Loving, C.L.2    Manischewitz, J.3    King, L.R.4    Gauger, P.C.5    Henningson, J.6
  • 49
    • 38749151911 scopus 로고    scopus 로고
    • Structural basis for the function and inhibition of an influenza virus proton channel
    • Stouffer A., Acharya R., Salom D., Levine A.S., Costanzo L.D., Soto C.S., et al. Structural basis for the function and inhibition of an influenza virus proton channel. Nature 2008, 451(7178):596-599.
    • (2008) Nature , vol.451 , Issue.7178 , pp. 596-599
    • Stouffer, A.1    Acharya, R.2    Salom, D.3    Levine, A.S.4    Costanzo, L.D.5    Soto, C.S.6
  • 50
    • 18744377200 scopus 로고    scopus 로고
    • Influenza type A virus escape mutants emerge invivo in the presence of antibodies to the ectodomain of matrix protein 2
    • Zharikova D., Mozdzanowska K., Feng J., Zhang M., Gerhard W. Influenza type A virus escape mutants emerge invivo in the presence of antibodies to the ectodomain of matrix protein 2. JVirol 2005, 79(11):6644-6654.
    • (2005) JVirol , vol.79 , Issue.11 , pp. 6644-6654
    • Zharikova, D.1    Mozdzanowska, K.2    Feng, J.3    Zhang, M.4    Gerhard, W.5
  • 51
    • 67349085540 scopus 로고    scopus 로고
    • Monoclonal antibody recognizing SLLTEVET epitope of M2e protein potentialy inhibited the replication of influenza viruses in mdck cells
    • Wang Y., Zhou L., Shi H., Xu H., Yao H., Xi X.G., et al. Monoclonal antibody recognizing SLLTEVET epitope of M2e protein potentialy inhibited the replication of influenza viruses in mdck cells. Biochem Biophys Res Commun 2009, 385(1):118-122.
    • (2009) Biochem Biophys Res Commun , vol.385 , Issue.1 , pp. 118-122
    • Wang, Y.1    Zhou, L.2    Shi, H.3    Xu, H.4    Yao, H.5    Xi, X.G.6
  • 52
    • 84868695189 scopus 로고    scopus 로고
    • MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response
    • Testa J.S., Shetty V., Hafner J., Nickens Z., Kamal S., Sinnathamby G., et al. MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response. PLoS One 2012, 7(11):e48484.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e48484
    • Testa, J.S.1    Shetty, V.2    Hafner, J.3    Nickens, Z.4    Kamal, S.5    Sinnathamby, G.6
  • 53
    • 80052891501 scopus 로고    scopus 로고
    • Cross-protective peptide vaccine against influenza A viruses developed in HLA-A*2402 human immunity model
    • Ichihashi T., Yoshida R., Sugimoto C., Takada A., Kajino K. Cross-protective peptide vaccine against influenza A viruses developed in HLA-A*2402 human immunity model. PLoS One 2011, 6(9):e24626.
    • (2011) PLoS One , vol.6 , Issue.9 , pp. e24626
    • Ichihashi, T.1    Yoshida, R.2    Sugimoto, C.3    Takada, A.4    Kajino, K.5
  • 54
    • 85028103480 scopus 로고    scopus 로고
    • http://www.its-innovation.com/index.php.
  • 55
    • 34548711911 scopus 로고    scopus 로고
    • Synthetic multi-epitope peptides identified in silico induce protective immunity against multiple influenza serotypes
    • Stoloff G., Caparros-Wanderley W. Synthetic multi-epitope peptides identified in silico induce protective immunity against multiple influenza serotypes. Eur J Immunol 2007, 37(9):2441-2449.
    • (2007) Eur J Immunol , vol.37 , Issue.9 , pp. 2441-2449
    • Stoloff, G.1    Caparros-Wanderley, W.2
  • 56
    • 84861963299 scopus 로고    scopus 로고
    • Synthetic influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled phase I trial
    • 29
    • Pleguezuelos O., Robinson S., Stoloff G.A., Caparrós-Wanderley W. Synthetic influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled phase I trial. Vaccine 2012, 30(31):4655-4660. 29.
    • (2012) Vaccine , vol.30 , Issue.31 , pp. 4655-4660
    • Pleguezuelos, O.1    Robinson, S.2    Stoloff, G.A.3    Caparrós-Wanderley, W.4
  • 57
    • 85028125174 scopus 로고    scopus 로고
    • http://www.clinicaltrials.gov/ct2/show/NCT01226758?term=flu+v%26rank=2.
  • 58
    • 0032813525 scopus 로고    scopus 로고
    • Intranasal administration of peptide vaccine protects human/mouse radiation chimera from influenza infection
    • Ben-Yedidia T., Marcus H., Reisner Y., Arnon R. Intranasal administration of peptide vaccine protects human/mouse radiation chimera from influenza infection. Int Immunol 1999, 11:1043-1051.
    • (1999) Int Immunol , vol.11 , pp. 1043-1051
    • Ben-Yedidia, T.1    Marcus, H.2    Reisner, Y.3    Arnon, R.4
  • 59
    • 84908076255 scopus 로고    scopus 로고
    • Preparedness ahead of pandemic outbreaks
    • Gottlieb T., Hassin S., Ben-Yedidia T. Preparedness ahead of pandemic outbreaks. BioProcess Int 2013, 11(S9):20-25.
    • (2013) BioProcess Int , vol.11 , Issue.S9 , pp. 20-25
    • Gottlieb, T.1    Hassin, S.2    Ben-Yedidia, T.3
  • 60
    • 61549132283 scopus 로고    scopus 로고
    • Auniversal epitope-based influenza vaccine and its efficacy against H5N1
    • 26
    • Adar Y., Singer Y., Levi R., Tzehoval E., Perk S., Banet-Noach C., et al. Auniversal epitope-based influenza vaccine and its efficacy against H5N1. Vaccine 2009, 27(15):2099-2107. 26.
    • (2009) Vaccine , vol.27 , Issue.15 , pp. 2099-2107
    • Adar, Y.1    Singer, Y.2    Levi, R.3    Tzehoval, E.4    Perk, S.5    Banet-Noach, C.6
  • 61
    • 85028125126 scopus 로고    scopus 로고
    • http://www.BiondVax.com.
  • 62
    • 84862776631 scopus 로고    scopus 로고
    • Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans
    • Wilkinson T.M., Li C.K., Chui C.S., Huang A.K., Perkins M., Liebner J.C., et al. Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans. Nat Med 2012, 18:274-280.
    • (2012) Nat Med , vol.18 , pp. 274-280
    • Wilkinson, T.M.1    Li, C.K.2    Chui, C.S.3    Huang, A.K.4    Perkins, M.5    Liebner, J.C.6
  • 63
    • 85028116571 scopus 로고    scopus 로고
    • Priming by a novel universal influenza vaccine (multimeric-001) - a gateway for improving immune response in the elderly population
    • in press.
    • Atsmon J, Caraco Y, Ziv-Sefer S, Shaikevich D, Abramov E, Volokhov I, etal. Priming by a novel universal influenza vaccine (multimeric-001) - a gateway for improving immune response in the elderly population. Vaccine, in press.
    • Vaccine
    • Atsmon, J.1    Caraco, Y.2    Ziv-Sefer, S.3    Shaikevich, D.4    Abramov, E.5    Volokhov, I.6
  • 64
    • 85028125486 scopus 로고    scopus 로고
    • http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/BloodVaccinesandOtherBiologics/VaccinesandRelatedBiologicalProductsAdvisoryCommittee/UCM330392.pptx.
  • 65
    • 84865366747 scopus 로고    scopus 로고
    • Pierre Youinou: when intuition and determination meet autoimmunity
    • Jamin C., Renaudineau Y., Pers J.O. Pierre Youinou: when intuition and determination meet autoimmunity. JAutoimmun 2012, 39:117-120.
    • (2012) JAutoimmun , vol.39 , pp. 117-120
    • Jamin, C.1    Renaudineau, Y.2    Pers, J.O.3
  • 66
    • 84884352609 scopus 로고    scopus 로고
    • Rethinking mechanisms of autoimmune pathogenesis
    • Pillai S. Rethinking mechanisms of autoimmune pathogenesis. JAutoimmun 2013, 45:97-103.
    • (2013) JAutoimmun , vol.45 , pp. 97-103
    • Pillai, S.1
  • 67
    • 84884284703 scopus 로고    scopus 로고
    • Abul Abbas: an epitome of scholarship
    • Gershwin M.E., Shoenfeld Y. Abul Abbas: an epitome of scholarship. JAutoimmun 2013, 45:1-6.
    • (2013) JAutoimmun , vol.45 , pp. 1-6
    • Gershwin, M.E.1    Shoenfeld, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.